Aspartate aminotransferase mụbara, gịnị ka ọ pụtara, na ihe

Ahụ anyị, ma eleghị anya, e nwere ike ikwu kasị "elu technology", nke kere Nne Nature. Na ya, na onye ọ bụla ahụ bụ ihe pụrụ iche na ya "Ọdịdị" na ya ike, ọ bụghị dị ka ihe ijuanya dị ka ọ bụ pụtara ìhè. Ma ọ bụrụ na ị na-amụ n'ime ọmụmụ nke dum organism, ọ bụ ike izute a ọnụ ọgụgụ nke mgbagwoju okwu. Mgbe mgbe, ike na ule i nwere ike ịhụ ndị dị otú ahụ unpronounceable ahịrịokwu dị ka aspartate aminotransferase ụba. Ka ọ dịgodị, ọ na-ezo aka amino acid cleavage isiokwu. Ọ bụ uru na-matakwuo na a okwu a obere nso.

Olee ụdị okwu?

N'okpuru nyere okwu a pụtara ihe enzyme nke atụ ke cleavage ọrụ, fọrọ nke nta ka ọ bụla amino acid ke idem. Belatara, ọ kpọrọ SGOT ma ọ bụ AST na-owụt ke isi obodo leta. The enzyme dị na anụ ahụ nke ọtụtụ akụkụ, ndị dị ka:

• imeju;
• obi;
• akwara anụ ahụ;
• akụrụ;
• muscle;
• pancreas;
• splin;
• ìhè;
• ụbụrụ anụ ahụ.

Ọzọkwa, ọtụtụ n'ime ndị na enzyme na anụ ahụ nke obi, akụrụ, akwara sel, imeju.

N'ihi ya, nchoputa nke ọ bụla ọrịa metụtara ndị a ozu pụtara na aspartate aminotransferase ụba. Na akpa ume, splin na pancreas enzyme ego bụghị otú nnukwu. Ebe nwoke ahụ bụ dị iche iche si a nwanyi elu ọrụ iwu.

arụmọrụ AST

The enzyme bụ a protein molekul nke a na-agbala cellular anụ ahụ nke esịtidem akụkụ. Ya Ọdịdị guzobere Russian ọkà mmụta sayensị na 70s. The ọrụ nke enzyme bụ iji mee ngwangwa Biochemical Jeremaya mere na mkpụrụ ndụ. Na òkè nke vitamin B6, ọ bụ omume na mgbanwe nke amino asịd. Na mgbagwoju mgbanwe nke ọtụtụ amino asịd, gụnyere aspartic, e guzobere ọhụrụ compound. Ọ bụ ekele ya na njikọ nke glucose, nke bụ otú ọ dị mkpa maka ahụ anyị.

atụmatụ AST

Onye ọ bụla n'ime anyị n'oge ọ chere ihu na okwu ndị dị ka aspartate aminotransferase ụba. Gịnị ka ọ pụtara, ọ maara bụghị onye ọ bụla. Na nke a, anyị na-kpughee ákwà mgbochi. Na a ike organism na enzyme ẹdude ke sel nke si esịtidem akụkụ, bụ norm. Naanị a obere akụkụ nke AST nwere ike iru n'ime ọbara. Ozi - ịta nke enzyme na obi karịa ego nke ọbara na 10 puku ugboro.

Ma ọ bụrụ na anụ ahụ nke ihe ngwa mebiri emebi, ndị aspartate aminotransferase, na-atọhapụ, n'ime ọbara na ego nke enzyme-amalite na abawanye. Uto ọnụego na-adabere na ogo nke anụ ahụ mebiri. Ihe atụ, na nchoputa nke myocardial infarction, AST ịta esịmde a ọnụ ọgụgụ kasị elu mgbe ụbọchị.

Mgbe ụfọdụ, ndị enzyme ozo nwere ike gafere na ọnụego nke 5 ugboro, na ndị dị otú ahụ na-egosi nwere ike nọ maka 7 ụbọchị. Ma mgbe ahụ, mmadụ pụrụ ịnọ na-eche ma ọ bụrụ na ndị aspartate aminotransferase (AST) ụba, gịnị ka ọ pụtara? Nke a na elu ọrụ bụ ihe e ji mara oké ọnọdụ onye ọrịa, bụ nke na-agwụ ọjọọ pụta.

Ọ bụrụ na-abawanye na enzyme kasịnụ nwayọọ nwayọọ ma na-amụba ọnụego, ọ pụtara na infarct mpaghara enwekwu. aspartate aminotransferase ọrụ pụrụ ịkpata a anwu nke imeju anụ ahụ.

Gịnị nwere ike ize elu ọrụ nke AST?

Ọtụtụ mgbe, a elu ịta nke AST n'ime ọbara stream akpata ya myocardial infarction. Mgbe a ego nke enzyme nwere ike karịa ugboro 10 na norm, na elu ya bụ, nke ukwuu nke ebe gbasara obi muscle ọnya. N'ụbọchị nke anọ nke ọgwụgwọ a na-emekarị nyere reanalysis. Ya pụta na-egosi, aspartate aminotransferase ụba ma ọ bụ. Bụrụ na nke irè ọgwụ ga ibelata ya ịta.

Elu nke AST pụrụ hụrụ na ọnya nke imeju n'ihi ọtụtụ ihe:

• Oncological ọrịa.
• Mmanya nsi.
• Ibu oké ibu.
• Ọnụnọ nke HCV.

Naanị na nke a, na-eme ezi ihe nchoputa, ọ dị mkpa iji na-eduzi ọzọ ule. Otú ọ dị, elu-etoju nke enzyme nwere ike ịbụ na ma ndị ahụ siri ike. Dị ka ihe atụ, ọrụ nwere ike ịbụ:

• The ụmụaka na ọnụnọ nke mbufụt.
• Na inyom n'oge mbụ trimester nke afọ ime.
• Ọ bụrụ na oké mmanya na-aba n'anya.
• Mgbe na-ewere ọgwụ ụfọdụ eme: valerian, dị iche iche ọgwụ nje ma ọ bụ paracetamol.

Great omumu, kwa, nwere na nke a a-ezighị ezi mmetụta. Ke adianade do, ma ọ bụrụ na aspartate na-amụba, ndị mere nwere ike ezobe na ojiji nke preparations dabere na barbituric acid oriri nke gbochie afọ nwekwara ike iduga na-abawanye na AST.

Mere amụba AST

Akpata ụba etoju nke enzyme, ka ugbua kwuru n'elu, nwere ike ịbụ a myocardial infarction. Na a nchoputa na 95-98% niile ọrịa aha elu ọrụ nke aspartate aminotransferase. The uru pụrụ ịbụ ruo 3,000 nkeji egosi. / L. N'ọnọdụ ndị ọzọ, elu-etoju nke enzyme hụrụ imeju necrosis. The ọrịa a, n'aka nke ya, nwere ike mere site na iche iche iche iche nke ịba ọcha n'anya. Larịị nke AST na nke a karịa ndị nkịtị ụkpụrụ 10-100 ugboro.

Tinyere ihe ndị ọzọ ọrịa uru arịba rịaworo, nnukwu pancreatitis, mgbochi nke opi mgbailu, cancer mkpụrụ ndụ ma ọ bụ imeju metastases. Ọzọ enzyme ịta nwere ike ụba n'ihi ihe ọjọọ, a apa ọkụ usoro malite ịnwụ muscle mkpụrụ ndụ gụrụ ikpo ujo. Nke a nwere ike na-agụnye inwe ndidi na postoperative oge.

Gịnị aspartate aminotransferase mụbara nwa, o nwere ike na-egosi na ọnụnọ nke ịba ọcha n'anya, muscular dystrophy, nnukwu myocarditis, jaundice.

Ihe mere ẹsụhọde AST

enzyme etoju nwere ike ọ bụghị nanị na-amụba ma na-ibelata. Nke a na-eme dị iche iche ihe. Dị ka a na-achị, ọ pụtara na ụmụ nwaanyị dị ime. N'ọnọdụ ndị ọzọ na ụmụaka na ndị okenye ruru muscular dystrophy, unan ná mgbanwe nke ogo, ọrịa ụbụrụ infarction, hypothyroidism ma ọ bụ nnukwu pancreatitis hụrụ a belatara larịị aspartataminotraferazy. N'ihi a enweghị vitamin B6 ma ọ bụ site na -agbawa nke imeju na-chọpụtara erughi nke protein molekul.

Egosi maka analysis nzube

The analysis chọpụta larịị nke enzyme AST ga-rụrụ iji ịchọpụta ọnụnọ nke ụfọdụ dị oké njọ pathologies:

• ime ma ọ bụrụ cancer Filiks ke imeju mkpụrụ ndụ;
• ma e nwere metastases;
• aspartate aminotransferase ụba ọbara nwere ike na-egosi na ọnụnọ nke na-efe efe mononucleosis ma ọ bụ malitere ịrịa ọrịa nke lymphatic usoro;
• ụdị autoimmune ọrịa (e.g., DMD-Becker) ;
• myocardial infarction;
• imeju;
• analysis na-egosikwa ọnụnọ nke ọ bụla na ụdị nke ịba ọcha n'anya, gụnyere imeju necrosis.

Ke adianade do, nhata nke uru ahụ na-imeju, dị ka a kacha nta, na-eme ndị mmadụ na-eche banyere nnyefe nke analysis.

Naanị n'ihi guzosi ike ma ọ bụ ịgbagha nchoputa. Nke a ga-ekwe ka na-dị mkpa jikoro na oge. Ọ bụrụ na ọ bụla isi mgbanwe weere ọnọdụ, ọ bụ naanị ka mma.

Nkwadebe - otu ihe dị mkpa ọnọdụ

Ka Itie ụfọdụ ule ruo analysis ga-emeso kpọrọ dị ka na-ewere ọgwụ, ma ọ bụ a dọkịta oru ọgwụ ma ọ bụ herbal decoction, nwere ike imetụta pụta nke analysis na-etịbe.

Ya mere, ịmata kpọmkwem, aspartate aminotransferase ụba ma ọ bụ, i kwesịrị ịkwụsị ịṅụ ọgwụ. Ọ bụrụ na n'ihi ihe ọ bụla nke a bụ ekwe omume, ọ ga-agwa ndị dọkịta kwesịrị inye ndị niile na ozi banyere ọgwụ. Ya bụ, na onunu ogwu na oge nke ya nkuchi. Women laabu ule nwere ike ibibi a ime.

Analysis na arụmọrụ ụkpụrụ

Ihe maka nnyocha bụ nanị venous ọbara ma ọ bụ ọbara. Ya nlele a rụrụ na ihe efu afo nke ụtụtụ. The dum usoro anaghị a otutu oge na-ewe ebe na-enweghị ihe mgbu. N'ihi bụ njikere mgbe 6-10 awa. The ọbara nwere ike ịchekwa maka 48 awa na okpomọkụ nke 15-25 ogo. Na oyi na ọnọdụ (2-8 ° C) na ọ nọgidekwara banyere 6 ụbọchị.

Ma ajụjụ, ebe ọ bụ omume na-agabiga ihe dị otú ahụ analysis, ọ dị mkpa itinye na pụrụ iche laboratories na-arụ ọrụ Biochemical nyochara. Mgbe ụfọdụ, na-amụta AST (aspartate aminotransferase) ụba ma ọ bụ otú o kwesịrị, ị nwere ike ịga ọmụmụ ụlọọgwụ na ya obi ma ọ bụ ihe ọ bụla ọgwụ na ahụ ike ikwu alụmdi. Naanị ị ga-akpa ịchọpụta ma ya lab ndị dị mkpa ngwá na ngwaọrụ maka analysis.

Nkịtị etoju ke ọ bụla otu nke ndị mmadụ nwere onwe ha. Ka ihe atụ, ịta nke AST na nwa ọhụrụ bụ 25-75 U / L, mgbe ubé okenye ụmụaka (1-18 afọ), ọ bụ 15-60 U / L. Nkịtị etoju ke inyom mbio 10 36 U / l, na ụmụ nwoke - 14 ruo 20 U / L.