Drug "mebendazole". Ntuziaka maka ojiji

Drug "Mebendazole" ( "Vermoxum", "Vormin") na-atụle ga ukwuu irè anthelmintics. The ọgwụ dị na mbadamba ụdị na kwụsịtụrụ. Ya nọ n'ọrụ mgwa - mebendazole.

The ọgwụ nwere a iche iche sara mbara anthelmintic ọrụ. Ndị kasị dị irè ọgwụ maka trihotsefaleze na enterobioze. Ọgwụ nkanka njikọ nke cellular tubulin na ikpuru, disrupts ịrụ ọrụ nke cytoplasmic microtubules na-egbochi glucose itinye n'ọrụ na-egbochi guzobe ATP.

Mgbe e na agwọ ọrịa a na-etinye obi gị dum na a obere ókè. The ọgwụ nwere a dịtụ ala bioavailability, ruru akwa mbụ metabolism na zuru ezu ala solubility. Agwọ ọrịa "Mebendazole" (ndu nwere ihe ọmụma dị otú) anyụpụ na na nsị fọrọ nke nta kpamkpam.

The ọgwụ na-kenyere iji kpochapụ cestodes, nematodes. Egosi n'ihi na ya n'ikuku gụnyere hookworm, ascariasis, Enterobiasis, trichinosis, trichocephalosis. Drug "mebendazole" ntụziaka ntuziaka na-atụ aro na ị na-eji na echinococcosis, taeniasis, strongyloidiasis. The agwọ ọrịa na-kenyere na weere mwakpo.

Drug "mebendazole" ntuziaka maka ojiji adịghị ekwe ka eji na oké ọrịa nke imeju, hypersensitivity ya. Ọ bụghị na-atụ aro ọgwụ na ụmụ n'okpuru afọ afọ abụọ.

N'itinye ọgwụ na a ndabere nke oke helminthic mbuso agha na-zuru ezu ngwa mwepụ nke nje nwere ike ime (na ụfọdụ), abdominal mgbu (-akwụsị akwụsị), isi ọwụwa, afọ ọsịsa. Mgbe ụfọdụ, e nwere ọgbụgbọ ma ọ bụ vomiting. Ruo ogologo oge ọgwụgwọ na elu doses nke agwọ ọrịa echinococcosis n'ọnọdụ ụfọdụ hụrụ neutropenia. Ekwe Omume n'akụkụ Jeremaya mere na-eosinophilia, na anaemia. Mgbe ụfọdụ, na ọrịa n'oge ọgwụgwọ na ọgwụ pụtara nfụkasị Jeremaya (ọkụ ọkụ, angioedema, itching ma ọ bụ aṅụ). Adịkarịghị hụrụ ntutu ọnwụ, nakwa dị ka cylindruria, hematuria.

Ọrịa okenye karịrị afọ iri na enterobioze na nkà mmụta ọgwụ "mebendazole" ntụziaka ntuziaka na-atụ aro na ego nke otu narị milligrams. Children n'okpuru afọ iri inye iri-na-ise ma ọ bụ iri ise milligrams. The nkwadebe na nke a na-e ozugbo. Na nke abụọ ojiji nke ihe ize ndụ nke ibute ọrịa a rụrụ ọzọ agwọ ọrịa - mgbe abụọ ma ọ bụ izu anọ, n'otu usoro onunu ogwu.

Mgbe ankilostomidoze, ascariasis, trihotsefaleze ụmụaka na ndị okenye ọgwụ na-kenyere ugboro abụọ kwa ụbọchị maka otu narị milligrams (ụtụtụ na mgbede). Ọgwụgwọ a rụrụ maka ụbọchị atọ.

Mgbe mbuaha mwakpo, strongyloidiasis, taeniasis na-atụ aro dose n'ihi na ndị okenye - abụọ na narị abụọ milligrams ugboro abụọ n'ụbọchị. Children na-atụ aro ugboro abụọ n'ụbọchị maka otu narị milligrams. Ọgwụgwọ ahụ gaa n'ihu ruo ụbọchị atọ.

Na trichinosis ọgwụ "mebendazole" ntụziaka ntuziaka tụrụ aro iji na-esonụ atụmatụ: na-atọ ndị mbụ ụbọchị - ugboro atọ n'ụbọchị maka 200 ma ọ bụ 400 milligrams, nke anọ na iri ụbọchị - ugboro atọ n'ụbọchị maka 400-500 milligrams.

Mgbe echinococcosis ndinọ ugboro abụọ kwa ụbọchị 500 milligrams nke ọgwụ (na-atọ ndị mbụ ụbọchị). N'oge ọzọ ụbọchị atọ, ugboro nke ngwa na-ụba na ugboro 3 (otu onunu ogwu ekpe). Mgbe e mesịrị, ndị na-atụ aro kwa ụbọchị dose nke 25 ma ọ bụ 30 milligrams kwa kilogram nke ahu aro, atọ ma ọ bụ anọ doses.

Na ihe ovadozu ego hụrụ vomiting, afọ ọsịsa, na ọgbụgbọ. E nwekwara abdominal cramps. Na ndị a a gastric lavage eji a potassium permanganate ngwọta bụ ọtọ pink. Ekwe na-eji na-arụ ọrụ carbon.

The feasibility nke na-eji ọgwụ ọjọọ eme ihe "mebendazole" n'oge ime na lactation ọkachamara na-ekpebi. N'oge dum nke ọgwụ kwesịrị nlezianya ọcha. Ọ na-atụ aro ka ịbịa ọgwụgwọ maka niile ndị òtù ezinụlọ.

Tupu iji ọgwụ "mebendazole" mkpa ịkpọ onye dọkịta.