"Rosuvastatin": ntuziaka maka ojiji, reviews. Cheap analogue "rosuvastatin"

Ọgwụ "Rosuvastatin" a mara ebe 2003 na na-awa dị ka a statin Generation IV. Ọ bụ oge a na na elu-àgwà inhibitor nke gamma-methylglutaryl-CoA reductase. Nke a enzyme bụ maka na njikọ nke cholesterol na ahụ mmadụ. Ya mgbochi na-eduga ná a Mbelata endogenous cholesterol ma belata ihe ize ndụ nke ọrịa obi na ọrịa.

Ke adianade "rosuvastatin" e nwere ọtụtụ klas ogbo, òtù nke statin otu. Nke a "Simvastatin" "Pravastatin", "cerivastatin," "Lovastatin," "Fluvastatin," "Atorvastatin", "pitavastatin." Clinical nrụpụta na ọsọ mbenata ngụkọta cholesterol na ala-na-njupụta "Rosuvastatin" nke ọ bụ nanị "pitavastatin," nke a na-adịghị ma mee n'ọtụtụ ebe ruru ka obere akwakọba nchekwa data nke na-adakarị ọnwụnwa.

Ka ụbọchị, "atorvastatin" a na-eji ọtụtụ ugboro karịa ndị ọzọ statins n'ihi na nke ahụ bụ kasị saa mbara research isi na-egosi na ya na-adakarị irè. Ọzọkwa, ya na generics dị nnọọ ọnụ ala, "rosuvastatin". Ma, dị ka ndị ikpeazụ mmetụta (normalisation nke lipid profaịlụ nke ọbara plasma) bụ ngwa ngwa, na mgbe ọ na-amalite itinye ndị ọzọ ọtụtụ ebe. Nke a bụ a n'ezie àgwà ngwaahịa, nke na ọ ga-akwụ ụgwọ.

Ebe "rosuvastatin" na pharmacotherapy

Na nkwadebe "Rosuvastatin" ngwa, n'agbanyeghị na ịdị adị nke klas ogbo, pụtara sara mbara. Ọ na-akọwa ndị na-egosi na contraindications ejedebeghị. The na-egosi ugbu a na ọ fọrọ nke nta niile ụdị hypercholesterolemia na nke ọgba aghara nke lipid metabolism. The ọnụ atherogenic lipid fractions nwere uru ndị na organism. N'ihi nke a, ndị likelihood nke mmepe nke atherosclerotic ọnya na-ebelata, na ndu ndimmadu (na àgwà) dịkwuo dịtụ.

Nkwadebe "Rosuvastatin" mee ihe mgbochi nke ọrịa obi, ọrịa na-emeso ha. Ikpeazụ niche pharmacotherapy dị n'ihi na mmegbu nke ndị Filiks nke atherosclerosis na endothelial stabilization nke ihe e dere ede. Ebe ọ bụ na ọrịa ụbụrụ infarction na obi ịzụlite si nnukwu thrombosis eduga akwara, mgbe ahụ na-adakarị mmetụta n'ezie aka egbochi nnukwu akwara ihe.

Ntuziaka maka ojiji

Mmasị ka ọgwụ ọjọọ "Rosuvastatin" ntụziaka ntuziaka (analogues dị otú ahụ akwụkwọ dị) nwere a warara iche nke na-egosi maka ojiji. Otú ọ dị, ọ na-adịghị nwere ihe ọ bụla ndidi ozi na a chọrọ tupu iji chọpụta ihe na-nta nke cholesterol. N'ọdịnihu, ha mgbanwe ga-enyocha adakarị nrụpụta ọrụ nke ọgwụgwọ na a ụfọdụ onunu ogwu. Ọzọkwa okwu e dere ozi banyere nchebe anya na atụmatụ nke ọgwụgwọ, contraindications, na ihe ndị kasị ugboro ugboro na ịrịba mmetụta.

egosi

N'etiti ọrịa niile metụtara na ụba plasma lipid fractions, pụta ìhè ụfọdụ adakarị egosi:

• heterozygous butere n'aka (ezinụlọ) hypercholesterolemia;
• nkewa site Fredrickson polygenic hypercholesterolemia ụdị IIa;
• jikọtara dyslipidemia, nkewa site Fredrickson otú IIb;
• Homozygous ezinụlọ (ezinụlọ) hypercholesterolemia;
• akwara, ọrịa ụbụrụ ma ọ bụ gbasara akụrụ ọrịa mgbasi akwara, occluding na lumen nke akwara;
• Atherosclerosis nke akwara nke ala na nsọtụ, gụnyere Leriche syndrome ;
• hypertriglyceridemia (IV ụdị dị ka Fredrickson);
• ọgwụgwọ nke myocardial infarction na ụbụrụ, ebe ọ bụ na nnukwu oge;
• mgbochi nke myocardial infarction na ọrịa strok.

contraindications

Ọ bụla dị ọnụ ala karịa analọg "rosuvastatin" nwere otu mmetụta dị ka ihe mbụ "Crestor". Na ndabere nke ha ụdịdị dị iche iche contraindications guzobere, nke ndị dị ka ndị:

• hepatic cytolysis syndrome ọrịa na hepatocytes na ndị ọzọ karịa atọ-n'ogige atụrụ na-abawanye na transaminase kasịnụ;
• mmebi imeju, imeju na scores nke 9 Child-Pugh;
• adịghị ala ala gbasara akụrụ odida egosi na ọrụ na creatinine nwechapụ erughị 30 ml \ min.;
• Myopathy nke ọ bụla si;
• nfụkasị Jeremaya ka Nwa mmiri ma ọ bụ "Rosuvastatin".

E nwere otu ìgwè ndị ọzọ contraindications 40 mg onunu ogwu:

• adịghị ala ala gbasara akụrụ odida na-egosi creatinine nwechapụ erughị 60 ml \ min.;
• ọ bụla ketara eketa myopathies;
• concomitant ojiji na fibrates;
• aṅụrụma;
• Mongoloid agbụrụ;
• iji nke a statin maka oge mbụ.

Atụmatụ nke ọgwụ

All "rosuvastatin" - ọgwụ ọjọọ, analogues nke ndị a dị ọtụtụ ebe na ahịa. Na site na ị na-ahọrọ a akpan akpan ika aha, onye ọrịa kwesịrị na-na nkà mmụta ọgwụ na na. Ya bụ, ịgbanwe ọzọ ọgwụ enweghị ezi uche. Sam ọgwụ ẹka enweghị banyere nri mgbe ọ bụla nke ụbọchị. E nwere ihe ole na ole ndị ọzọ na-atụ aro nke ndị ọkachamara ndị na mbụ na-arụ ọrụ na nke mbụ ọgbọ statins. Ha na-ebu ozi na statins kwesịrị iwere na alakpu ụra. Ọ bụ ezie na ọ bụghị dị oké mkpa, dị ka ogologo dị ka ọgwụ e weere na banyere otu oge na nọgidere.

Ejikwa ha onwe ha ala ga-mgbe niile ruo mgbe nabata "Rosuvastatin" (analogues). Nyocha ekwe ọkachamara na-arụ ọrụ kasị mma si eme nke chọpụtara. Karịsịa, mgbe oruru nke ọnụnọ nke hypercholesterolemia-amalite na-ewere ọgwụ na a ofu dose. Mgbe 2 ọnwa nke nyochaa - lipidogram ugboro ugboro rụrụ na inyocha ọrụ nke aminotransferases.

Ọ bụrụ na e a normalisation nke lipid profaịlụ nke ọbara plasma, ọ na-achọrọ iji nọgide na-enweta n'ime otu dose. Ọ bụrụ na ngụkọta cholesterol anọgide elu, na ego nke ala njupụta cholesterol budata belata, na-amụba dose chọrọ. Ọ bụrụ na transaminase ụba ugboro atọ, na-achọ mwepụ nke statins. Ọ ga-karịsịa kwuru na ndị kasị nta na ime ka ihe cytolysis nke niile statins bụ "Rosuvastatin." Analogs (Ukraine nwekwara nwayọọ nwayọọ shifting si "atorvastatin" na "rosuvastatin") klas ndị na-erughị ala. A "pitavastatin" na-anọgide na-dịghị ihe ọzọ na-amụ.

Analogs "rosuvastatin"

Dị ka ihe ntụnyere, "rosuvastatin" ( "Crestor") ama enye ihe karịrị 10 ngwaahịa. N'etiti ha, "AKORT", "Merten", "Rozart", "Rozistark" "Rosuvastatin Canon", "Rosuvastatin SOTEX" "Rosuvastatin Nsụgharị Ụwa Ọhụrụ", "Rozulip", "Rozukard", "Roxer", "Rustor" " Tevastor ". The na-eri nke na-emeso ha dị iche iche, nakwa dị ka arụmọrụ. N'ihi na price nke ndị a ọgwụ ọjọọ nwere ike kere atọ ige:

• ala ahịa (site na 250 na 650 rubles), "Rosuvastatin Nsụgharị Ụwa Ọhụrụ", "Rosuvastatin Canon", "AKORT" "Rosuvastatin SOTEX";
• Nkezi ahịa (site na 400 na 900 rubles), "Merten", "Rozart", "Roxer", "Rozukard", "Tevastor", "Rozulip";
• elu ahịa (site na 1100 ka 2200 rubles): "Crestor".

price analysis e rụrụ site atụnyere ndị na-eri ọgwụ, ibu nke nọ n'ọrụ compound nke bụ 10 mg. The price nso na-egosipụta ndị na-eri otu ọnwa nke cholesterol-ẹsụhọde ọgwụ. The ọnụ ala analọg "rosuvastatin" arụpụtara site "Northern Star". "Rosuvastatin Canon" na "AKORT" bụkwa ubé dị iche iche na price. Ha na-eri bụ obere yiri ka ịgbanwe dabere na ọnụego mgbanwe fluctuations.

Otu nnyocha nke ndị dị ọnụ ala ọnyà "CRESTOR"

Ọgwụ "Rosuvastatin" wepụtara site Astrazeneca, a na-akpọ "Crestor". Nke a bụ mbụ na nkà mmụta ọgwụ, nke a ga-eji tụnyere ndị ọzọ niile. The otu na-emetụta comments: ndị e ji mara nke a akpan akpan ọnyà ngwaahịa a ga-dabere na ya tụnyere "Krestorom". Ma n'ihi na nke dịtụ elu na-eri, ọtụtụ ndị ọrịa ozugbo amalite ọgwụgwọ nke hypercholesterolemia na dị ọnụ ala karịa generics.

Ebumnobi ọmụma nanị ọkachamara nwere ike inye na a nyochaa, onye na-abụkarịkwa ndị ojiji nke generics na "rosuvastatin" na mbụ "CRESTOR". A etinyere ọgwụ "Rosuvastatin 'ntuziaka maka ojiji, ndidi testimonials na-adakarị ahụmahụ ga-ekwe ka ndị ọzọ ọrịa na-ahọrọ a akpan akpan ahia aha.

Nyocha nke ọkachamara "Crestor" na generics

Tụlee "CRESTOR" rụrụ naanị site ọkachamara nke Russian Society of Cardiology. Nke a na ozi a na-e bipụtara na magazin "ò pharmacotherapy na Cardiology." Karịsịa, ọ na-agwa okwu nke bioequivalence nke ọnyà ọgwụ ọjọọ, "Crestor". Dị ka ihe pharmacoeconomic ọmụmụ gosiri na ọgwụ ọjọọ "Merten", "Rozart", "Roxer", "Rozukard" na "Rozulip" bioequivalent "Crestor".

Nke a pụtara na ihe ọ bụla "rosuvastatin" Nke a ntụnyere nwere a ọgwụgwọ mmetụta yiri mbụ ọgwụ nwere otu nọmba na ogo nke mmetụta. Mgbe ọgwụ "Rosuvastatin Nsụgharị Ụwa Ọhụrụ", "Rosuvastatin Canon", "Rosuvastatin SOTEX" na "AKORT" dị otú ahụ ule na-adịghị mee ihe. N'ihi na ndị a mgbakọ na mwepụ ọmụmụ na-adịghị kwụrụ ụgwọ site na-emepụta ọgwụ na ụlọ ọrụ, na n'ihi ozi bụ ebumnobi na-ezukọ na-adakarị atụmatụ nke ọgwụgwọ nke hypercholesterolemia. Otú ọ dị, na-arụpụta nanị maka mba ọzọ generics.

Nyocha nke ọkachamara cheap generics "rosuvastatin"

Modern analogue nke a ọnụ ala "rosuvastatin" ga ha bioequivalence "Crestor" na mgbe ahụ, ọ na-akpaghị aka ọkọkpọhi ùgwù nke ndị ọkachamara. Enweghị bioequivalence ọmụmụ ọkachamara nwere ike banyere naanị adakarị atụmatụ nke ngwa. Otu n'ime ha bụ nke a: ma ọ bụrụ na-eji anọgide dị ọnụ ala karịa ndị ogbo "rosuvastatin" (ọgwụ ọjọọ e depụtara n'elu), ugboro nke oghom ihe yiri hụrụ mgbe iji ọnyà bioequivalent "Crestor".

Fluctuations na plasma ịta "rosuvastatin" ịda site na ojiji nke a siri ike onunu ogwu ụdị na a dị iche iche mejupụtara, na-atụle na-adịghị mkpa na nke a. N'ihi na ọnụ ala Russian analogue nke "rosuvastatin" pụrụ n'ezie dochie mbụ ọgwụ "Crestor" na ya ọnyà ọgwụ ọjọọ maka ọgwụgwọ nke hypercholesterolemia.

Njirimara nke ọrịa reviews

Dị ka Ibọrọ nke ọrịa na-ekere òkè ha amụta banyere iji ọgwụ ọjọọ eme ihe na dọkịta gị, e nwere ọtụtụ nkwubi okwu ezi uche. Firstly, ọrịa ikpe banyere àgwà nke ọgwụ na-abụchaghị eziokwu. Nke abuo, n'ihi na nke imperceptible onye ọrịa na-adakarị mmetụta nke a na-agbaso na ọgwụ bụ ala, ọ bụ ezie na ọgwụgwọ dị mkpa iji gbochie ihe ize ndụ nke nnukwu akwara ihe. Nke atọ, ndị ọrịa na-imebiga ihe ókè dị mkpa nke mmetụta na-eleda Ọnọdụ nke plasma lipid profaịlụ.