Triptans maka migraine. Triptans: ọgwụ ọjọọ ahịa

Migraine - a nsogbu n'ihi na ọtụtụ ndị ọrịa. Fọrọ nke nta onye ọ bụla dịkarịa ala otu n'ime a ndụ ahụmahụ mgbu na isi. Dị ka a na-achị, ha na-esonyere dizziness, ọgbụgbọ, vomiting, nakwa dị ka nkụnwụ, tingling ma adịghị ike na nsọtụ, photo- na phonophobia. Mgbe otu agha, ọrịa mkpesa nke ike ọgwụgwụ, lethargy na iro ụra. Mgbe ụfọdụ, e nwere otu mgbe ọrịa na otú na-agba ọsọ, na ike na-enyere onye ọrịa triptans isi ọwụwa. Ọ ga-kwuru na migraine - a ọrịa nke ndị inyom, ka ha na ndị ọzọ susceptible ka ndị dị otú ahụ daa ọrịa, karịa mmadụ. Odika 10-18% nke ndị toworo eto chọpụtara na migraine.

The nsogbu nke isi ọwụwa maara onye ọ bula

Ọtụtụ ndị na-adịghị achọ enyemaka si a ruru eru ọgwụ na-agba mbọ iji nagide ọrịa, mgbe na-ewere analgesics. Ọ baghị uru ikwu, otú ahụ anaghị aka, ma naanị njọ ọrịa. The na-achịkwaghị achịkwa ojiji nke analgesics nwere ike ime ka mmepe nke ọgwụ ruru ala ala isi ọwụwa. Ya mere, ọ bụghị ihe ijuanya na e nwere nnukwu ọtụtụ ajụjụ banyere ụdị isi ọwụwa ọgwụ - kasị dị irè.

Kpamkpam gwọọ migraine agaghị ekwe omume, ma iji melite ogo nke ndụ bụ na o kwere omume pụrụ iche na ngwaahịa, nke na-họpụtara a ọkà mmụta ọrịa akwara. E nwere ugbu a mara a nnukwu ego nke migraine na-zuru ezu irè ma n'oge agha, na na interictal oge. Ọzọ, a Ilerukwu ọgwụ maka migraine: a ndepụta nke ego na nnukwu agha-free ọgwụ. E gosipụtara na triptans - kasị irè ọgwụ ọjọọ iji kpochapụ oké isi ọwụwa. Na prophylactic ọgwụ ọjọọ na-kenyere ndị na-esonụ iche iche:

• β-blockers;
• antidepressants;
• antiemetic;
• mmiri-soluble vitamin B;
• calcium blockers;
• anticonvulsants.

Ịnakwere niile n'elu họọrọ dị ka pharmaceuticals ga-ahọpụta a ruru eru onye.

Gịnị mere a isi ọwụwa?

Tupu ị na-aghọta otú na-eme ihe triptans isi ọwụwa, ego nke nke na-adabere na emeputa, ọ dị mkpa ịghọta na usoro nke daa ọrịa. Isi ọwụwa amalite n'ihi mmetuta nke anabata nke meninges na ọrịa ụbụrụ arịa. Mgbe oké nrụgide ma jupụtara ọbara arịa, karịsịa veins, emi odude ke a hypotonic ala amalite n'oké ihe mgbu, nke a pụrụ tutu amama naanị site pụrụ iche pharmaceuticals. Ọtụtụ na-eme nnyocha na-anya ruo ogologo oge, preparations maka ọgwụgwọ nke migraine, kwubiri na triptans - kacha mma n'aka ka adreesị a daa ọrịa.

Njirimara triptans

The ọgwụ iji na ibelata dilated arịa nke ụbụrụ. Triptans - a na nkà mmụta ọgwụ na-eme na ntọala na-anabata ya nke trigeminal akwara, nke n'aka nke na-ebelata ihe uche nke ihe mgbu mbata. Triptans - oge a antimigraine ọgwụ ọjọọ, nke nwere a kama elu selectivity na ọbara arịa nke Dura mater (Dura mater encephali) na dịtụ obere na elu na akwara arịa.

Ọkọnọ ọgwụ dị irè na mbenata mgbu n'ogo nke spinal ntọala nke trigeminal akwara. Ke adianade niile n'elu triptans - ọgwụ ọjọọ eme ihe na-apụghị naanị belata omume nke ọrịa nlọghachi azụ, ma na-ewepụ Associated adakarị ngosipụta nke ya (eg, ọgbụgbọ, vomiting, photophobia, na ụda).

Isi uru nke triptans

Ndị a pharmacological Njirimara nke elu na-agba webatara N'ihi. N'ụzọ nkịtị na ọkara otu awa na e nwere ihe ịrịba ama nke uru nke ọgwụ na ọrịa ahụ. The ọgwụgwọ mmetụta nọgidere na-enwe ofụri migraine agha. Ihe ka nnọọ ọtụtụ nke ọrịa isi ọwụwa na-adịghị lọghachiri.

Ụbọchị ndị a, ndị ọkà mmụta sayensị gosi na nchọpụta nke precursors nsogbu kwesịrị ozugbo triptans maka migraine. Tupu mgbe e nwere na nchepụta nke na migraine ọgụ a ga-emeso na nkebi, malite na n'ikuku nke mfe ọgwụ.

Drugs maka migraine: a ndepụta nke kasị ewu ewu na ọgwụ

Na triptan ìgwè nke ọgwụ ọjọọ na-agụnye ndị na-esonụ:

• 'Zomig'.
• "Amigrenin".
• "Sumatriptan".
• "Imigran".
• "Relpaks".
• "Trimigren".
• "Sumamigren".
• "Rapimed".
• "Almotriptan".
• "Naramig".
• "Naratriptan."
• "Frovatriptan."
• "Zolmitriptan."

The ọgwụ ọjọọ ọ bụla ndidi ike nditịm onye, ya mere iji hụ na irè nke a ma ọ bụ ndị ọzọ ọgwụ, ndị dọkịta nwere ike ikwu na-agbalị na-ewere ya maka atọ migraine ọgụ. Tryptamine ìgwè nke ọgwụ ọjọọ e ji elu bioavailability, ha ndị dịtụ mfe imeri ọbara-ụbụrụ mgbochi, bụ irè na mbenata migraine ọgụ, ọbụna na-egbu mgbu na-adọ. A ọgwụ kwesịrị ekwesị nye iwu ka ọrịa na-agafeghị oke ka oké ọrịa ntaramahụhụ.

ngwa Notes

Ọtụtụ mgbe anyị na-anụ otu ajụjụ: ihe isi ọwụwa ọgwụ dị mma? Na ọmụmụ gosiri na ndị kasị dị irè iji kpochapụ ihe mgbaàmà nke migraine bụ triptans. Ọ kasị mma na-triptans maka migraine mgbe ọ na-achọpụta na mbụ ihe ịrịba ama nke agha. The kacha analgesic mmetụta e hụrụ ruo awa abụọ mgbe na-ewere ọgwụ. Tupu ewere a ọgwụ, jiri nlezianya na-agụ ntụziaka na ịkpọ a dibịa. Ọ dị ezigbo mkpa iji gbochie ọgwụ ovadozu. Triptans maka migraine adịghị atụ aro iji ọnụ na ọgwụ nje, antifungal, antiviral mmadụ, nakwa dị ka na antidepressants.

Iji nweta chọrọ N'ihi ya, ọrịa ga-esoro ndị na-esonụ ụkpụrụ nduzi maka inweta triptans:

• na nke dị nwayọọ na agafeghị oke isi ọwụwa lee 1 mbadamba (ma ọ bụ onye na dose ịgba);
• abụọ dose-e bụghị tupu 2 chasa;
• n'oge ụbọchị adịghị karịa abụọ doses;
• triptans na-atụ aro ka ewe ihe karịrị ụbọchị abụọ n'izu.

N'oge ọgwụgwọ nke ihe oriri gị ga-ekwe tiraminsoderzhaschie Ngwaahịa:

• koko;
• chocolate;
• agwa;
• àkwá;
• celery;
• citrus;
• ekwukwa n'akwụkwọ Mmeju;
• chiiz;
• tomato;
• mkpụrụ;
• na-aba n'anya.

Otu gaghịkwa eri oyi nri.

Na omume nke migraine triptane, na price nke ga-egosi n'okpuru, nwekwara ike ga-eji na ndị ọzọ ọgwụ ọjọọ eme ihe, dị ka metoclopramide ma ọ bụ domperidone.

mmetụta

Mgbe a ọgwụ ovadozu, ọrịa na-eche ihu na-esonụ nsogbu:

• dizziness;
• anaphylactic ujo;
• tightness;
• ọgbụgbọ;
• mmetụta nke ịhụnanya;
• infarction nke splin, eriri afọ;
• vomiting;
• akọrọ ọnụ;
• myalgia;
• abdominal mgbu;
• iro ụra;
• ere ọkụ sensashion na akpụkpọ;
• Angioedema;
• tachycardia;
• aṅụ;
• polyuria;
• muscle adịghị ike;
• ebelata anya;
• sensory disturbances;
• haemorrhagic afọ ọsịsa;
• Ugboro urination;
• akwara vasospasm.

N'agbanyeghị ihe a nile, triptans maka migraine - a ngwa ngwa-eme ọgwụ. Isiokwu onunu ogwu na ugboro ole nke na-aṅụ ọgwụ ize ndụ nke mmetụta dị ntakiri. Ke ofụri ofụri, ihe niile triptans anabata ahụ kwesịrị. Mmetụta, ma ọ bụrụ na ha ga-eme, mgbe ahụ kwuru nwayọọ na-edozi spontaneously enweghị ọgwụ aka. Isi drawback nke triptans - a bụ na ha na-eri. N'ụzọ dị mwute, ọ bụghị ihe niile ndị ọrịa nwere ike imeli otú a ọgwụ.

contraindications

Triptans maka migraine adịghị ike ikwu iji na-esonụ mgbe:

• strok;
• angiospastic rịaworo;
• ime;
• cerebrovascular mberede;
• n'oge ara-udia a nwa;
• coagulopathy (ọbara clotting);
• na-eto eto;
• ọrịa nke obi usoro;
• hypersensitivity ka bioactive bekee nke Nwa;
• n'echeghị echiche ọbara mgbali;
• arrhythmia;
• imeju na-na akụrụ ọrịa;
• atherosclerosis.

Tupu prescribing ụfọdụ triptans, na ịga dibịa kwesịrị mata ihe ize ndụ ihe maka atherosclerosis. A ihe na-agụnye ndị na-esonụ:

• arịa ọrịa shuga;
• post-menopausal inyom;
• ise siga;
• ọbara mgbali;
• ibu oké ibu;
• a elu larịị nke ndiiche ọbara cholesterol;
• afọ karịrị afọ 40 n'ihi na ndị ikom;
• mkpụrụ ndụ ihe nketa pụrụ ịrịa a obi ọgụ.

Ụfọdụ ndị ọrịa na n'ihe ize ndụ ga-enweta ihe mbụ dose of tryptamine n'okpuru nlekọta nke a ọkachamara na n'okpuru ECG akara.

Scheme n'imeso migraine

E nwere n'ozuzu ụkpụrụ nke ọgwụgwọ ọgwụgwọ nke ọrịa na-agu n'onye ezi omume ọtụtụ mgbe:

• dị mkpa na-amalite usoro ọgwụgwọ na analgesics ma ọ bụ n'ịgwa ya (gụnyere ndị so ná ndị mgbochi mkpali ọgwụ ọjọọ);
• Ọ bụrụ na ịnụ ọgwụ ojiji adịghị enye a nti utịp, mgbe ahụ, mgbe minit 45 ga-ewere a triptan;
• ma ọ bụrụ na a triptan kemgbe adighi ike, na-esote agha ga-eji ọzọ ọgwụ si triptanovoy otu;
• na gbara gharịị isi ọwụwa bụ mkpa na-eji ndị na-abụghị steroidal mgbochi mkpali ọgwụ ọjọọ.

The ojiji nke oge a na ngwá ọrụ maka ọgwụgwọ nke migraine, kere na ndabere nke triptans, na-enyere eme ka ndụ mfe n'ihi na ọtụtụ ọrịa. Echefula na-ewere ndị a ọgwụ pụrụ kenyere onye dọkịta, na na mgbe nchoputa. E nwere ọnọdụ mgbe triptans na ndị ọzọ na nonspecific analgesics adịghị enye chọrọ N'ihi na adịghị ewepụ ihe mgbu. Na nke a, ndị dọkịta na-emekarị nye iwu a mgbagwoju ọgwụ na anticonvulsant ọgwụ, na beta-blockers. Ọgwụ ndị a na-agụnye ndị na-esonụ ọgwụ ọjọọ:

• "Penbutolol".
• "Nadolol."
• "Betaxolol."
• "Topiramate".
• "Neurontin."
• "Phenobarbital".
• "Timolol".
• "Propranolol".
• "Labetanol".
• "Bellataminal".
• "Metoprolol".
• "Topamax".
• "Acebutolol".

Olee otú iji belata omume nke ọgụ?

Iji belata ugboro nke migraine ọrịa aghaghị ịgbaso ụkpụrụ ndị a:

• eri mgbe nile;
• ewepu gị nri oriri na ọṅụṅụ na-akpalite ọgụ (biya, chocolate, cheese, champeenu, citrus mkpụrụ osisi, red wine);
• ịkwụsị ịṅụ sịga
• dị ka ọ bụ kwe omume na-n'èzí ọzọ;
• zere nchegbu;
• Mgbatị (ezigbo - igwu);
• zere ogologo njem ụgbọ ala, ụgbọ mmiri, ụgbọ ala.

Triptans bụ a isi ọwụwa: na price

Triptans na-emepụta dị iche iche onunu ogwu iche: injection ngwọta, ọ dịghị òkè ịgba, mbadamba, rectal suppositories. On na-eri nke ọgwụ ọjọọ na-emetụta ntọhapụ ụdị, onunu ogwu, ọnụ ọgụgụ nke mkpụrụ ọgwụ na a ngwugwu. Dị ka a N'ihi ya, price nke ọgwụ ndị a dịgasị na a dịgasị iche iche - 150-1500 rubles kwa mkpọ.