Akpụ welara ca 19-9. Analysis nke ca 19-9: norm na mgbe ọ kpọlitere

Akpụ welara ca 19-9 bụ a elu molekụla ibu glycoprotein. Ọ na-emepụta site na mkpụrụ ndụ na epithelium nke digestive usoro. Dị ka a nnyocha usoro eji immunohemilyuminestsentny analysis. Ca 19-9 jikọtara kansa pathologies.

ozi izugbe

Na-amụ ndu ihe onwunwe dị ka a na-eji venous ọbara. Ca 19-9 - irè akpụ welara. Ya definition na-eji na nchoputa, nlekota na n'oge nchọpụta nke metastasis na afo, pancreas, imeju, eriri afọ (colon na ikensi). Ca 19-9 etoju mụbara na fọrọ nke nta niile ọrịa na eriri afọ etuto ahụ, karịsịa nke pancreas. Ịmịpụta mkpụrụ ndụ na etuto ahụ, glycoprotein penetrates n'ime systemic mgbasa. Idebe ihe na-eleru ọdịnaya, ndị ọkachamara nwere ohere ịgbaso ụzọ nke ọrịa. Analysis nke CA19-9, ọnụego nke na onye ahụ dị mma karịa 10 U / ml na-adịghị eji na isi nchoputa.

Gịnị bụ pancreatic cancer? nchịkọta

Nke a oncological ọrịa ụbọchị a gụnyere na ndepụta nke kasị dị ize ndụ pathologies. About 90% nke ọrịa anwụ n'ime afọ mbụ nke ọrịa. Mgbe oge nke nchoputa na 80% nke ọrịa chọpụtara na n'ime ime obodo ma ọ bụ mpaghara metastases. Ọkachamara na-ekwu nke a tumadi na-ezo n'elu daa ọrịa. The ọrịa mgbe nwogharia dị ka ala ala mkpali Filiks ke eruba mpaghara hepatopancreatoduodenal akụkụ (cholelithiasis, cholecystitis, ala ala pancreatitis). Na njikọ na nke a mkpa ka anya dị ka o kwere omume na-ebu a esi nchoputa, ewepu ọnụnọ nke malignancy. Nke a, n'aka nke ya, ga-họrọ ndị kasị dị irè ọgwụgwọ atụmatụ nke ndị a na-adịghị ala ọnọdụ.

Antigen ca 19-9. ịta

Na cancer nke pancreas e a elu larịị nke glycoprotein. Analysis nke CA19-9, bụ nke nwere n'elu-achị, na-achọ nchọpụta nke carcinoma, na-eleru omume resection. Na a ịta nke ihe karịrị 1000 U / ml neoplasm lere operable naanị 5% nke ọrịa. Ọ bụrụ na ọdịnaya bụ n'okpuru gosiri na ọnụ ọgụgụ, na-akpụ na-emekarị ga-ewepụ. Otú ọ dị, mgbe ndị na aka nke a oge nke otu na ọnwa asaa, e nwere ihe ize ndụ nke nlọghachite. Akpụ welara ca 19-9 bụ nke abụọ kasị mkpa mgbe welara CEA maka ịchọputa malignancy ke afo. Ke adianade do, ọmụmụ ihe ọzọ elu molekụla ibu glycoprotein kenyere Alfa-fetoprotein na nchoputa na nlekota nke ọgwụgwọ nke imeju cancer, biliary tract na eriri afo.

abawanye nke

Elu etoju nke glycoprotein pụrụ hụrụ na a ndabere nke dị iche iche na mkpali na benign pathologies na imeju na digestive usoro (ruo 500, ma na-emekarị ka 100 U / ml), na cystic fibrosis. Ke akpa idaha ịta na-ụba na 12% nke ọrịa. The kacha larịị na nke a - adịghị karịa 45 U / ml. Glycoprotein anyụpụ na bile. Na nke a, ọ bụla cholestasis nwere ike so onye na-abawanye na ya ọdịnaya. N'ọnọdụ dị otú ahụ, ọ dị mkpa na-eduzi nnyocha n'out oge GGT (gamma-glutamattransferazy) na alkaline phosphatase. Mụbara ịta nwekwara ike-hụrụ na a ndabere nke ọzọ localizing etuto ahụ (na nke eriri cancer, ovarian cancer), ọrịa imeju (imeju, ịba ọcha n'anya).

Enweghị ma ọ bụ belata larịị

Ndị ọkachamara achọpụtala na nkịtị ịta anaghị ewepu ọnụnọ nke cancer na pancreas. Na nke a, ọ ga-chọpụtara n'oge ogbo ọrịa mgbe larịị bụghị ma nwere oge ebili. The ọmụmụ ndị ọrịa na-anata ọgwụgwọ, ẹsụhọde ọdịnaya nke glycoprotein nwere ike na-egosi na ịdị irè nke ọgwụgwọ adọ.

Nke na-achọ nnyocha

Ule ruo akpụ welara ca 19-9 dị mkpa iji nyochaa irè nke ọgwụgwọ adọ maka pancreatic cancer, nakwa dị ka oge mbụ nchọpụta ọrịa nlọghachite. The ọmụmụ na-enye ohere a esi nchoputa nke malignancy na ọrịa ndị ọzọ (e.g., pancreatitis). Egosi ca 19-9 na-egosi na njupụta nke ịza usoro, ọnụnọ nke cancer na ndabere nke anya metastases nke ọrịa.

Mgbe ụfọdụ, ihe ọmụmụ e kenyere

Ule ruo akpụ welara ca 19-9 na-atụ aro maka ngosipụta nke mgbaàmà nke ọrịa cancer nke pancreas: ọgbụgbọ, ihe mgbu ke afo, jaundice, arọ ọnwụ. N'oge ruo n'oge ọmụmụ e kenyere ọrịa na ihe ibido akwa ịta nke glycoprotein na inweta ọgwụgwọ. Analysis akwadoro maka-enyo enyo na cancer na ńsí eriri afo ma ọ bụ biliary tract, imeju, afọ ma ọ bụ colon. Research otú ndinọ na Nchikota na ndị ọzọ bịara.

transcript

The akwụkwọ uru nso nke ga-abụ larịị nke antigen - 0-35 U / ml. Ka ugbua kwuru n'elu, na-akwa ịta nke glycoprotein egosi ọnụnọ nke malignancy n'anyịnya. The elu ọdịnaya, ihe ọzọ dị elu ogbo ọrịa. Oké etoju na-egosi akpụ metastasis.

ozi dị mkpa

Test content atụle glycoprotein dị mkpa karịsịa ke akpa nchọpụta nke metastatic mgbasa nke cancer na pancreas. About 7-10% nke ndị mmadụ na-adịghị site n'usoro na-ebu ụzọ amata elu molekụla ibu glycoprotein. Ntem, ke idem e a mkpụrụ ndụ ihe nketa ike synthesize na antigen ca 19-9. N'ihi ya, ọbụna na nchoputa nke malignancy larịị nke glycoprotein na-adịghị ahụrụ na ọbara.

Maka ozi ọzọ,

Tupu ị onyinye ọbara, ndị ọkachamara nwere ike ikwu na agaghị m aṅụ sịga n'ihi na ọkara otu awa. The na-achọpụta ọrịa uru nke ule na-abawanye, mgbe ọmụmụ na CEA. Ke adianade mwube kasị ọma chọpụta na ihe kwesịrị ekwesị oru mkpa ọgwụgwọ na-atụ aro ule ca 72-4, ngụkọta bilirubin, Azu 242. Laboratory ọmụmụ inye ndị dị otú ahụ ndị ọkachamara dị ka hepatologist, internist, dọkịta na-awa ma ọ bụ oncologist.

ọgwụgwụ

Ndị ọkachamara kwuru na taa cancer na pancreas bụ esiwanye nkịtị na ọrịa mgbe afọ 30. Nke a daa ọrịa bụ otu n'ime-agụghị oké achọpụtara na-agụghị oké amenable ka ọgwụ. Na nke a, ihe ndị kasị enwe mmetụta ọsọ ọsọ ule na-ọ dị mkpa ka a mara ya. N'ụzọ dị mwute, na-amụ antigen ịta ike ga-eji maka mbụ nchoputa nke ọrịa ogbo. O sina dị, nke a ule bụ ihe kasị enwe mmetụta ọsọ ọsọ na ihe ọmụma maka eleru irè nke ọgwụgwọ, nchọpụta nke n'oge nkebi nke metastasis nke cancer. Obi abụọ adịghị ya, a ọkachamara na nnyocha na-eji ihe ndị dị iche iche achọpụta na usoro. Na mgbakwunye na ime nnyocha, onye ọrịa na-họpụtara na instrumental nnyocha. The kasị inweta nke a bụ ugbu a US. Na-eduzi ya ọkachamara nwere ike ịmata akpụ size si abụọ sentimita. Iji dokwuo anya size, ọnọdụ, na mgbasa nke malignancy nye iwu a CT iṅomi. Iji usoro a, ọ nwere ike achọpụtara site akpụ size atọ sentimita. Ọ ga-kwuru na omume nke CT na jikọọ na-emepụta a na-dose of X-ụzarị. Ya mere, nke a na-amụ adịghị rụrụ ugboro ugboro ma ọ bụ dị ka prophylaxis. Obere nchegbu na ọrịa ahụ na-enye ihe MRI. Ma nke a ụdị nnyocha na-adịghị rụrụ mmadụ nwere ọ bụla metal implants. All ndị a na-achọpụta ọrịa jikoro, tinyere ọbara ule nwere ike ịchọpụta n'oge nkebi nke cancer mmepe ma ọ bụ metastasis n'anyịnya.