-Alụso ọrịa ọgụ na thyroid peroxidase

Thyroid peroxidase enzyme bụ a glycoprotein okike. Nke a microsomal antigen bụ ihe kasị mkpa na njikọ nke thyroid homonụ.

The autoimmune usoro metụtara autoantibodies na nsụkọrọ akpụ thyroid gland. Aghara nke thyroid ọrụ a na-ejikọta ya na ya. Nke dị oké mkpa na nke a na-alụso ọrịa ọgụ megide thyroid peroxidase.

The kasị elu ịta ojoo Hashimoto si thyroiditis. Na ikpeazụ nkebi nke atrophic Filiks ke thyroid ha larịị na-lowered na ụfọdụ na undetectable etoju.

-Alụso ọrịa ọgụ na thyroid peroxidase na-mata na ili 'ọrịa. Na oge nke ha njirimara maka ọrịa metụtara ihe ize ndụ ihe maka ụdi guzobere hypothyroidism.

Mgbe susceptibility ka tireoditu Hashimoto inyom nwere alụso ọrịa ọgụ na tireperoksidaze nwere ike achọpụtara n'oge ime. Na ha ụba ịta ke akpa trimester e bụ likelihood nke na-emepe emepe na ọrịa mgbe amuchara nwa.

-Alụso ọrịa ọgụ na thyroid peroxidase na ike na-egosi na ọnụnọ nke ọzọ thyroid pathologies. A na-agụnye, karịchaa, kwesịrị gụnyere adenoma, goiter, thyroid cancer. Ọzọkwa,-alụso ọrịa ọgụ na-detectable na ike mmadụ (ihe dị ka 10% nke ndị inyom na 5% ndị ikom).

Laboratory nnyocha na ha njirimara ga-rụrụ n'agbanyeghị nke ụdị nke autoimmune usoro. Ọ bụ ma e wezụga na -arịa ọrịa shuga (insulin-ndabere), pernicious anaemia, adrenal insufficiency (autoimmune), systemic lupus erythematosus.

Ngwa nke onye ọgwụ ọjọọ pụrụ ịkpata mmepe nke hypothyroidism, nke a na-ejikọta ya na ọdịdị autoantibodies. A na-agụnye, akpan akpan, lithium ọgwụ ọjọọ, "Amiodarone". Mmetụta dị otú ahụ bụ ihe e ji mara nke immunostimulatory ọgwụ (eg, interferon).

Mkpebi siri ike nke-alụso ọrịa ọgụ bụ ya zuru ezu mwute ule maka nchọpụta nke autoimmune mbibi nke ndị na thyroid gland. N'ihi ya ukwuu-achọpụta ọrịa uru ka kpọmkwem akara.

Rịba ama na guzosie ike na ịdị adị nke ihe autoimmune ọrịa nke thyroid gland na na ndabere nke kwuru na ọ bụ elu index-alụso ọrịa ọgụ agaghị ekwe omume.

Zuru oke na-egosi maka ọmụmụ bụ ili 'ọrịa, ihe ize ndụ amụma nke hypothyroidism on dịpụrụ adịpụ ndabere nke na-amụba ịta nke thyroid-akpali akpali hormone. Ke adianade do, mkpa maka analysis n'akparamagwa autoimmune thyroiditis na isi hypothyroidism, nakwa dị ka ndị amụma nke mmepe nke ọbara thyroiditis na ọrịa na n'ihe ize ndụ.

Maka ikwu na-egosi na-agụnye

- esi nchoputa nke subacute na autoimmune (lymphocytic) thyroiditis na ndabere nke transistor thyrotoxicosis,

- Diagnosis nke autoimmune forms na ndabere nke euthyroid asị ibe ma ọ bụ nodular goiter,

- ịkọ hypothyroidism na ọrịa na n'ihe ize ndụ, n'oge ime.

Na ọgwụgwọ nke kwuru na ọ bụ ọrịa na-elu-na-amụ bụ na-ekwesịghị ekwesị. Nke a bụ n'ihi na eziokwu na ya larịị nwere dịghị prognostic uru mgbe a chọpụtara na ọrịa.

Na ọnụnọ nke likelihood nke autoimmune thyroid ọrịa na-atụ aro retested na mbụ na nke abụọ afọ nke chọpụtara na ikpe ke akpan ọmụmụ, ọ dịghị-alụso ọrịa ọgụ na thyroid peroxidase. The norm maka ahụ ike mmadụ bụ ruo 35 IU / ml.

Taa e nweghị ọkà mmụta sayensị pụtara na ụda usoro ọgwụgwọ na Ait (autoimmune thyroiditis). Ọnụ na nke a, na ndabere nke ike hypothyroidism, thyroid peroxidase-alụso ọrịa ọgụ mgbe, a na-ọgwụgwọ nke ọrịa abụghị a nsogbu n'ihi na dọkịta. Họpụtara ndị hormone nnọchi ọgwụ ọgwụ ọjọọ, "Levothyroxine."