Erosion nke afọ: etiology na pathogenesis

Ozize nke afo - a pụtara nkịtị ọrịa, e ji guzobe erosions n'elu mucous akpụkpọ nke afo. Akwụsị ndị a na-egosi na ha bụ necrosis dị elu. Mgbe ha na-agwọ ọrịa, a naghị emepụta ụdọ anụ ahụ njikọ. Mgbu nke afọ bụ usoro nosology nke na-ejikọta usoro mmebi ihe na-adịghị ala ala na mucosa gastric. Mgbe ụfọdụ, ọ na-egosipụta onwe ya dị ka ihe mgbaàmà nke gastritis. Ya mere, n'ime akwụkwọ ndị a, a na-akpọ ọrịa a ka ọ bụrụ eriri afọ nke afọ.

The isi na-akpata ọrịa na-oké gburugburu ebe obibi ihe na-mgbe niile na-eme na ahụ mmadụ. Ihe ndị a na-akpata nchekasị (ọkụ, frostbite, mmerụ, ujo, polytrauma) na-akpata mmebi nke usoro nchịkwa nke usoro nke ọtụtụ akụkụ, karịsịa, trophic na secretory ọrụ nke afọ na eriri afọ, belata nkwụsị nke organism. Enwekwara mkpụrụ ndụ ihe nketa na ọrịa ahụ. Mgbu nke afọ nwere ike ime na ọgwụ (nitrofurans, corticosteroids, ethacrynic acid, veroshpiron, tolbutamide), ịṅụbiga mmanya ókè, na ọrịa endocrine (ọrịa shuga, hyperparathyroidism).

Ọtụtụ ndị kweere na erosive mgbu na-ebilite si pathogenic edinam nke Campylobacter (Helicobacter pylori) na ahụ mmadụ. Ihe ndị mere eme gosiri na pasent 95 nke ndị nwere ọnya duodenal nwere ụdị ọrịa campylobacteria, mana ndị ọrịa nwere ọnyá ahụ na-enwe nanị pasent 6% nke ndị niile nwere ọrịa a.

Mgbaju nke afo: pathogenesis (mmepe nke ọrịa)

N'okpuru mmetụta nke ihe isi ike ndị dị na ahụ, e nwere mgbagwoju anya na mmekorita usoro ọgwụgwọ nke na-esote site na mmebi nke ụjọ na usoro humoral nke usoro iwu nke ọrụ nile, karịsịa afo na eriri afọ. Mụbara secretion nke adrenal cortex homonụ na histamine, nke welie secretion nke gastric ihe ọṅụṅụ na onye na-abawanye na ọrụ nke pepsin na ya ọdịnaya nke free hydrochloric acid. N'otu oge ahụ, secretion na viscosity nke imi na-ebelata, nke na-ebelata ọrụ nchebe nke mucosa. Tụkwasị na nke ahụ, enwere mkparịta ụka nke uru na afo na eriri afọ, ọnwu nke capillaries na-abawanye, trovism nke anụ ahụ kwụsịrị, bụ nke na-eduga na mmeghachi omume mkpali, mmepụta ero na ọnya nke mucosa gastric. Onye kwesiri iburu n'uche ihe ndi mmadu na-egbu egbu na abuo mucous. Ya mere, na ngwọta nke oke mmiri, njikọ bụ isi bụ ọdịiche dị n'etiti ọrụ mgbochi nke mucosa na ikike mbibi nke ọdịnaya ọdịnaya nke eriri afọ ma ọ bụ eriri afọ. N'inye ọnụ ọgụgụ nke arịa ọbara, ọbara ọgbụgba na-apụta n'ebe ahụ na ọnya afọ. Na ọrịa a ịzụlite ufọk ufene ọtọ afo ọrịa, eriri afọ, imeju, pancreas na ndị ọzọ na akụkụ na usoro.

Ọtụtụ mgbe (30-90%) na ndị na-eto eto, ọrịa ahụ na-agafe n'enweghị ihe ịrịba ama ụfọdụ. Mgbe ụfọdụ, enwere nrekasi obi, belching utoojoo, enweghi ike inwe mgbu na afo. Oge na-adịghị ala ala nke gastritis erosive gosipụtara onwe ya na njirimara nke ihe omuma. Ihe dị ka pasent 80 nke ndị ọrịa na-eme mkpesa nke nrekasi obi, mmebi, ihe mgbu na njiri elu nke elu, flatulence, afọ ọsịsa na afọ ntachi.

Ndị a chọpụtara na ha ga-erute gastritis nke afọ kwesịrị ịgbaso nri e ji mee ihe iji belata ọrụ nke ihe ọṅụṅụ mmiri. Iji mezuo ihe mgbaru ọsọ a, i kwesịrị iri nri. Nke mbụ, ihe oriri na mbido nke afọ gụnyere ịjụ ihe oriri na-edozi ahụ, bụ nke bara ọgaranya na cellulose (radish, meat veins, turnips, bread flour, etc.). Ị gaghị eri nri ndị e ghere eghe. Ọ kwesịrị izere na-aba n'anya, carbonated mmiri, citrus, kọfị, aja aja nri, nakwa dị ka oyi na-ekpo ọkụ oriri.