"Mirapex": ntuziaka maka ojiji, nkọwa, reviews

Ke ibuotikọ emi ị ga-amụta ihe niile banyere nkwadebe "mirapex": otú dochie a ọgwụ, ihe bụ nke ya mmetụta, contraindications, mmetụta, ntụziaka a kapịrị ọnụ na aka ya. Mkpụrụ ọgwụ ndị a nwere ike ime ka ndiiche omume na mmetụta na ọrịa omume. Ya mere, tupu ewere nke a ọgwụ "mirapex" ntuziaka maka ojiji ga-nlezianya mụọ. Anyị na-agwa gị banyere ndakọrịta nke mkpụrụ ọgwụ ndị a na ndị ọzọ ọgwụ ọjọọ.

Ruo ogologo oge "mirapex": general ọmụma banyere ọgwụ na-egosi maka ojiji

N'ọrụ umi nke nkwadebe "mirapex" bụ pramipexole. Inyeaka mmiri Mbadamba: povidone, mannitol, starch, aerosil, magnesium stearate.

Na nke a na-aṅụ ọgwụ na-rụrụ mgbawa (onwe ha nke ọzọ ọnya) syndrome nke "na-erughị ala ụkwụ" na ọrịa Parkinson nakwa dị ka ndị ọzọ a nụchara anụcha moto na extrapyramidal ọrịa.

Product: mkpụrụ ọgwụ "mirapex PD" 3 mg, 4.5 mg, 1.5 mg, 0,75 mg, 0,375 mg. Ha na-juru n'ọnụ na blisters nke 10 mbak, na mgbe ahụ na katọn.

ọcha ọgwụ. Ha nwere a beveled ihu na ewepụghị udi na abụọ, na otu onye nke nwere a ukwuu n'ihe ize ndụ.

Mbadamba kwesịrị iwere ọnụ, n'agbanyeghị nri. Rie ọgwụ na-ekwe na n'oge ọ bụla. Na nke a, ọ ga-asa ala na mmiri. Aro ya kwa ụbọchị dose ekewa atọ.

The usoro nke edinam (pharmacodynamics) "mirapex" Mbadamba

Irè pramipexole àkù nke ihe mejupụtara nkwadebe "mirapex" kpọmkwem na na elu selectivity enhances nzaghachi nke subgroup nke dopamine anabata D2. N'ihi ya, ụgwọ atụrụ maka adịghị emega ahụ na ihe banyere ọrịa Parkinson. Nke a bụ n'ihi ebighị nke dopamine anabata na striatum. N'ihi ya pramipexole egbochi ndị mbelata nke akwara ozi na-adị n'ihi na neurotoxicity ma ọ bụ ischemia. Ọ na-egbochi ma ọ bụ na-ebelata ọnụego njikọ, metabolism, ma hapụ dopamine. Ekele pramipexole akwara ozi na-echebe site na-egbu egbu na mmetụta nke mgbochi Parkinson mmadụ "Levodopa". Ọzọkwa ruru ya mmetụta mbelata prolactin (dose-ndabere).

Na ikpe nke ruo ogologo oge iji mkpụrụ ọgwụ "mirapex" maka ọgwụgwọ nke ọrịa Parkinson (karịa afọ atọ) na syndrome nke "na-erughị ala ụkwụ" (ihe karịrị otu afọ) ekpugheghị belata arụmọrụ nke pramipexole.

Biochemical Filiks metụtara nkwadebe "mirapex 'na a ọrịa ahu (pharmacokinetics)

Active umi "mirapex" ọgwụ na-kpam kpam na ngwa ngwa etinye obi gị dum mgbe onu ochichi. Ya ike maka assimilation (bioavailability) bụ fọrọ nke nta zuru - karịrị 90%. The kacha ịta nke ọgwụ na plasma hụrụ mgbe 1-3 awa mgbe eri. Na nri pramipexole absorption ọnụego mbelata. Na nke a, na ego nke digestible nri na-agbanwebeghị.

C-edozi ejikọ pramipexole ubé (erughị 20%). Ọ nwere nnukwu nkesa olu - 400 lita, nke pụtara na ịta na ọbara bụ ala. Iji a obere n'ókè gụrụ ọgwụ metabolism usoro. Odika 90% nke dose "mirapex" pellets anyụpụ site akụrụ, na 80% - na-agbanweghi agbanwe. The na nsị pramipexole a hụrụ na ego nke na-erughị 2% nke iwesa ego nke ọgwụ. Anụ ahụ na mmiri ahụ na-ọcha site "mirapex" mbadamba na nkezi ọnụego nke 500 ml / min.

Eji "mirapex" ọgwụ ọjọọ n'oge ime

Enwere m ike iji n'oge ime "mirapex" mbadamba? Ntuziaka maka ojiji nke ọgwụ na-eme ka o doo anya na mmetụta nke ọgwụ na mmepe nke nwa ebu n'afọ na akpa nwa na lactation bụghị e nyochaworo.

The omume mmetụta nke pramipexole na usoro na ndị ọchịchị na-akpata njikọta usoro e mụọ nwere na ụmụ anụmanụ. Ọ na-adịghị na-egosipụta imebi nke nwa ebu n'afọ na mmepe n'oge ime na òké bekee oke.

Excretion nke pramipexole n'ime mmiri ara na a na-amụ. Otu nwere ike na-iche na umi nwere ike inhibit lactation, ebe na-egbochi mmepụta luteotrophic hormone. Ya mere, na-adịghị-"mirapex" Erere n'oge ara.

N'oge ime, ọgwụ kwesịrị iwere na ọ bụrụ na ndị nwere uru nne kari n'ọdịnihu n'ihe ize ndụ ka nke nwa ebu n'afọ.

Contraindications ojiji nke mbadamba 'mirapex "

Drug "mirapex" ike iwere na ikpe nke na hypersensitivity ka pramipexole, nakwa dị ka ndị na-erubeghị afọ 18.

Na pụrụ iche ịkpachara anya na-atụ aro iji mbadamba nkume n'okpuru belata ọbara mgbali na akụrụ odida.

Mmetụta "mirapex" ọgwụ ọjọọ na ụjọ usoro

Nkwadebe "mirapex" - mbadamba nke nwere ike ime ka ụjọ usoro na-esonụ kwuru:

• mgbagwoju anya;
• oké agụụ maka ụra ma ọ bụ enweghị ya;
• ịmụ anya arọ nrọ;
• obi nchefu;
• asthenia;
• dizziness;
• extrapyramidal syndrome;
• hypoesthesia;
• tremor;
• myoclonus;
• dystonia;
• ịda mbà n'obi;
• delirium;
• igbu onwe;
• hypokinesia;
• ataxia;
• nchegbu;
• neuroleptic ajọ syndrome.

Ikpeazụ hụrụ na ụdị hyperthermia, disturbances nke nsụhọ na-eche, muscle rigidity, autonomic lability, akathisia.

Mmetụta nke ọgwụ "mirapex" na ndị ọzọ na usoro nke ahụ mmadụ

Nweekwa usoro nwere ike ime ojiji nke ọgwụ "mirapex" dị ngosipụta:

• hypertonic mọzụlụ, ha ụfụ, twitching;
• omume nke ogbu na nkwonkwo, myasthenia gravis ma ọ bụ bursitis;
• mgbu obi, olu ma ọ bụ ọkpụkpụ azụ (na lumbosacral).

Ha nwekwara ike ime ka ọdịiche na digestive usoro. Mgbe nke a emee:

• ọnwụ nke agụụ;
• ntachi;
• ọgbụgbọ;
• dyspepsia;
• flatulence;
• afọ ọsịsa;
• vomiting;
• akọrọ ọnụ;
• ịcha mmetụta ke afo.

Akụkụ okuku ume na n'ikuku "mirapex" nke ọgwụ pụrụ ịkpata mmepe nke Sinusitis, pharyngitis, rhinitis, flu-dị ka syndrome. Ọ dịkwa ike omume nke iku ume ọkụ ọkụ, mụbara ụkwara na olu mgbanwe.

Gịnị bụ mmetụta na obi usoro "mirapex" mbadamba? Ntuziaka maka ojiji nke ọgwụ na-agwa banyere omume development tachycardia, arrhythmia, rịaworo pectoris, orthostatic hypotension.

Ọzọ mmetụta

Mgbe anata ọgwụ "mirapex" dị nsogbu nwere ike ime na urogenital usoro, dị ka ndị ọzọ Ugboro bowel mmegharị, ọrịa. N'ihi ya ọbụna kwesŽrŽ ọnwụ nke libido na potency.

Ke adianade do, ị nwere ike okpukpu abụọ ọhụụ, cataract, conjunctivitis, mkpọnwụ nke ulo, allergies, na mkpọchị ntị, ndị intraocular nsogbu.

Ndị ọzọ siri Jeremaya mere nke ahụ:

• retroperitoneal fibrosis;
• pleural effusion;
• akpa ume infiltration;
• arọ ọnwụ;
• elu edema.

Ọnụọgụ ọgwụ na Administration "mirapex" Mbadamba

Iji ọgwụ gị mkpa n'ime, kwa ụbọchị ugboro 3. Mbụ dose "mirapex PD" mbadamba - 0,375 mg kwa ụbọchị. Nke nta nke nta dịkwuo ego nke ọgwụ dị mkpa (ọ bụla 7 ụbọchị) nweta chọrọ ọgwụgwọ mmetụta. Na nke abụọ n'izu nke ọgwụgwọ ọ bụla ụbọchị ga-gwusia site 0,75 mg nke-atọ - ka 1,5 mg nke anọ - by 2,25 mg nke ise mkpa aṅụ ọgwụ "mirapex" 3 mg kwa ụbọchị, na nke isii - 3,75 mg, asaa - 4.5 mg.

Na-adịghị ala ala gbasara akụrụ odida, na onunu ogwu na-gbanwee dabeere na arụmọrụ larịị nke creatinine nwechapụ. Kpọmkwem ego nke ọgwụ ga-họpụtara a dọkịta.

Kpatara ovadozu Erere "mirapex"

Ọ bụrụ na ị na-eji "mirapex" ọgwụ onunu ogwu e tiwara, ndị a mgbaàmà nwere ike ime presumably ịmụ anya arọ nrọ, hyperkinesia, ọgbụgbọ, vomiting, ebelata ọbara mgbali na agụụ.

N'ihi ọnọdụ a, ihe ngwọta na-adịghị arụnyere. Ikpe nke ọgwụ ovadozu "mirapex" bụ ofu. Na-atụ aro symptomatic ọgwụ, gastric lavage na ike chọpụtara. Ọ bụrụ na e nwere ihe ịrịba ama nke ihe ovadozu nke excitation nke Central ụjọ usoro, ọ dị mkpa itinye preparations, neuroleptics.

Mmekọrịta mbadamba "mirapex" na ndị ọzọ ọgwụ ọjọọ eme ihe

Pramipexole metụtara plasma protein ubé ma biotransformation. Ya mere, ya na mmekọrịta ya na ndị ọzọ ọgwụ ọjọọ na-emetụta nke a Filiks bụ eleghi anya.

Drugs nke inhibit ma ọ bụ ebelata mmepụta nke-arụ ọrụ bekee ma ọ bụ cationic samovyvodyaschiesya site gbasara akụrụ tubules, nwere ike na-eme na mkpụrụ ọgwụ "mirapex". Ntuziaka maka ojiji na-akọwa na nke a na-agba ibelata pụta ìhè ọcha anụ ahụ na ndu oke mmiri ma ọ bụ site ma ọgwụgwọ ma ọ bụ otu n'ime ha.

Ọ bụrụ na n'out oge na mkpụrụ ọgwụ 'mirapex "mee ndị a ọgwụ ọjọọ eme ihe, ị ga-akwụ ụgwọ ntị na o kwere omume ịmụ anya arọ nrọ, dyskinesia, n'ahụhụ. Ọ bụrụ na ndị a ihe ịrịba ama ga-eme, na onunu ogwu nke ọgwụ ga-belata.

Ndakọrịta mbadamba "mirapex" ọgwụ "Amantadine" na "L-dopa"

Gịnị mere mgbe ndị jikọtara n'ikuku "Levodopa" ọgwụ ọjọọ na "selegiline" mkpụrụ ọgwụ "mirapex PD"? Ntụziaka na-ekwu na pharmacokinetics nke nọ n'ọrụ gị n'ụlọnga adịghị emetụta ma ndị mbụ ma ọ bụ abụọ. N'otu oge ahụ na full assimilation na excretion nke ọgwụ na a eke ụzọ "Levodopa" mbadamba "mirapex" na-adịghị ghọtara.

Pramipexole adịghị amụ mmekọrịta nke ọgwụ "Amantadine". Ma ndakọrịta bụ omume na ọgwụ, ebe ha nwere yiri usoro nke excretion.

Mgbe dose "mirapex" nkwadebe ụba, ngwa ego "Levodopa" na-atụ aro ka ibelata. The ọnụ ọgụgụ nke ndị ọzọ antiparkinsonian ọgwụ ọjọọ ga-aka iso mgbe niile na otu larịị.

Atụmatụ Ndakọrịta nkwadebe "mirapex" na ndị ọzọ ọgwụ ọjọọ eme ihe

N'ihi na o na-cumulative mmetụta na oké ịkpachara anya na-atụ aro iji mbadamba "mirapex" na Nchikota na sedatives, na mmanya, na ọgwụ ọjọọ na-enyere ntọt pramipexole ịta n'ime ọbara (e.g., a ọgwụ ọjọọ, "Cimetidine").

Specific nduzi na iji "mirapex" mbadamba

Anyị na-akọwa ọgwụ adịghị atụ aro na-na njikọ na antipsychotics.

Na ọgwụgwọ nke dopamine agonist mara mmetụta dị mgbagwoju anya na ịmụ anya arọ nrọ. N'ọnọdụ "mirapex" mbadamba na Nchikota na ọgwụ "Levodopa" dị abnormalities ndị ọzọ Ugboro na mgbe e mesịrị nkebi nke ọrịa karịa ná mmalite monotherapy.

The dọkịta ga-agwa onye ọrịa nke na o kwere omume omume nke visual ịmụ anya arọ nrọ. Nke a n'akụkụ mmetụta na-emetụta ikike iji ụgbọala ugbo ala na-eme ka ọrụ mkpebi.

Na nkọ discontinuation nke mbadamba na ihe banyere ọrịa Parkinson na-ahụrụ onye ahụ nke mgbaàmà na yiri neuroleptic ajọ syndrome.

Anomalous omume na ojiji nke "mirapex" ọgwụ

Ọrịa na ndị na-elekọta ha, ọ dị mkpa ịmata na n'ikuku nke dopaminergic ọgwụ ọjọọ, gụnyere "mirapex" mbadamba (reviews gosi na nke a), mgbe mgbe, na-akpata ọrịa ntutu ịdapụsị omume nke onye ọrịa. Ị nwere ike hyperphagia (iribiga nri ókè riri ahụ), enweghị nchịkwa shopping (oké ọchịchọ na-eme ka a otutu ịzụrụ), chaa chaa chaa na hypersexuality. N'ọnọdụ dị otú ahụ, ọ dị mkpa iji belata na onunu ogwu nke ọgwụ ma ọ bụ nwayọọ nwayọọ kwụsị ịṅụ ya.

Ịkpachara anya na iji "mirapex" mbadamba

Medicine "mirapex" ga-iwesa na-elezi anya ka ọrịa na ọnụnọ nke oké ọrịa nke obi usoro. Na-eduzi ọgwụ na dopaminergic ọgwụ e nwere ihe ize ndụ nke orthostatic hypotension. Ya mere, a ọbara mgbali akara, karịsịa na mbụ ogbo nke ọgwụgwọ.

Mgbe visual impairment dị mkpa mgbe nile na-elele ya ozugbo mgbe nhọpụta nke mbadamba "mirapex" na n'ihu kọwaa etiti oge.

Ọrịa e kwesịrị eziokwu na ọgwụ nwere ike a ogwuura mmetụta. E nwere mgbe nke mberede ụra na ịṅụbiga ụra n'oge ụbọchị na-eme. Gụnyere nke a nwere ike ime mgbe ọ bụla oge na management nke mgbagwoju ígwè ma ọ bụ na-akwọ ụgbọala ugbo ala.

Ekwe omume nke na-emepe emepe melanoma

Dị ka a n'ihi nke epidemiological ọmụmụ gosiri na ọrịa na ọrịa Parkinson nọ n'ihe ize ndụ nke melanoma. Ọ kpatara ọrịa a, ma ọ bụ ihe ndị ọzọ, dị ka iji "mirapex" ọgwụ ka e guzobere.

Iwusi nke syndrome nke "na-erughị ala ụkwụ"

Olee otú ndị syndrome nke "na-erughị ala ụkwụ" ọgwụ "mirapex"? Nleba na-egosi na dopaminergic ọgwụ ọjọọ nwere ike welie ya. Nke a na-egosipụta na ụdị nke mbụ mmalite nke mgbaàmà na mgbede syndrome na mgbe ụfọdụ na ehihie. Na nke a, ihe mgbaàmà igbasa na aka na ụkwụ. The ẹkenịmde maka 26 izu a na-adakarị achịkwa ọmụmụ, nke e mere na-amụ otú a, a ịrịba dị iche n'etiti pramipexole na placebo iche iche na ime atụmatụ nke syndrome e kwuru.

Nchekwa na ọnọdụ na adị ndụ

"Mirapex" mbadamba na-ezo aka a nkwadebe nke ndepụta B. Store ha ga-a gbara ọchịchịrị. Na nke a na-ụlọ okpomọkụ ekwesịghị gafere 30 Celsius C.

Adị ndụ nke ọgwụ - 36 ọnwa (3 afọ) site na ụbọchị nke mmepụta.

The iji "mirapex" mbadamba nwata na ọnọdụ nke zuo

The ọgwụ na-contraindicated maka ojiji na ụmụ. Ikike e nyere ikike mmadụ anata mbadamba, nke ruru afọ 18. Medicine "mirapex" wepụtara na pharmacies na ngosi nke a ọgwụ.

Drug analogues "mirapex"

Ị nwere ike, n'ihi na ihe ọ bụla mere, iji nweta mbadamba bụ "mirapex"? Gịnị nwere ike dochie ọgwụ, ị ga-agwa ndị na ọgwụ ma ọ bụ na dọkịta. Na anyị na-enye ndị na-esonụ analogues.

1. "Motopram" mkpụrụ ọgwụ. Egosi maka ojiji: Parkinson oria. Ọ nwere ike na-rụrụ naanị ma ọ bụ jikọtara na ọgwụ na nkà mmụta ọgwụ 'levodopa'. Ọ na-eji oké ma ọ bụ agafeghị oke mgbawa ụdị syndrome nke "na-erughị ala ụkwụ".
2. "Oprimeya" mkpụrụ ọgwụ. Nzube: antiparkinsonian usọbọ stimulant dopaminergic nnyefe ke Central ụjọ usoro.
3. "Pramipexole" mkpụrụ ọgwụ. The ọgwụgwọ gị n'ụlọnga eji na Parkinson oria. Ọ na-kweere na usoro nke edinam na-na na njikọ aka ike nke a umi pramipexole akpali dopamine anabata na striatum.

Mbadamba "mirapex" - analogues ma ọ bụ mbụ? Ọ dịghị onwe!

Na n'elu depụtara na ngwaahịa, nke na-analogues nke 'mirapex "mbadamba. Ha nwere otu ihe pụrụ iche, mba ndị na-abụghị proprietary aha (ma ọ bụ ATC-koodu), nke a na-atụ aro ndị WHO (Òtù Ahụ Ike Ụwa).

Ọ bụrụ na ị chọrọ ịbịa ọgwụgwọ iji mbadamba "mirapex" analogs nwekwara ike ịbụ oké ọzọ. Ma tupu i dochie họpụtara n'aka ọgwụ, jide n'aka na ịkpọ a ọkachamara. Ọ dịghị ihe ọ na-adịghị onwe! Nke a nwere ike ime ka irreversible-ezighị ezi pụta n'ihi na ike gị.

Warning! Isiokwu a bụ nkọwa nke "mirapex" nkwadebe gbakwunyere na mfe version nke ukara ntuziaka maka ojiji. Drug ozi ọkọnọ n'ihi nzube nke nyochaa. Na ọ bụrụ na-adịghị eji ya dị ka a na ndu ka onwe-ọgwụ.