Niacin ndu

Niacin, ntuziaka maka ojiji nke a ga-atụle n'isiokwu a, na-anọchi anya a vitamin na-agụnye oxidative Filiks aa na ihe dị ndụ na bụ ọgwụ. The ọgwụ na-dị n'ụdị a na-acha ọcha ntụ ntụ utoojoo uto na odorless. O siri ike igbari mmiri oyi.

Ọ ga-kwuru na nicotinic acid (ma ọ bụ vitamin eyi) bụ a vitamin, antiallergic, detoxification na gipolipedimicheskim gị n'ụlọnga nke na-eme ka mma nke carbohydrate metabolism, vasodilatation, gụnyere ụbụrụ, wega nke oxygen na anụ ahụ. Ọ na-agụnye abụba metabolism Filiks, amino asịd, ndi na-edozi na purines, nakwa dị ka na biosynthesis usoro.

Niacin, nke na-enye ntụziaka maka ojiji nke vitamin na iri abụọ na ise milligrams kwa ụbọchị, na elu doses (ruo anọ grams kwa ụbọchị) ebelata ego nke lipoproteins, triglycerides na cholesterol ke iyịp.

A ọgwụ na-ngwa ngwa etinye obi gị dum na eriri afọ tract, ma ghọọ nicotinamide iri anọ nkeji. Vitamin metabolized na imeju, na-synthesized na eriri afọ, nke na ngosipụta ebe nchekwa dị ka a metabolite.

Egosi maka ojiji nke ọgwụ na-: avitaminosis, parenteral oriri na-edozi, malabsortsiya, ịrịba ama na arọ ọnwụ, ọrịa amino acid assimilation, ọrịa eriri afọ tract, mụbara ahụ na-achọkwu eyi vitamin, fever, ịba ọcha n'anya, na-efe efe, nke nwere ala ala na ọdịdị, nakwa dị ka ịza aza etuto ahụ, afọ ime, lactation, nchegbu. Ọzọkwa, nicotinic acid, ntuziaka maka ojiji nke a na-mmasị ka ọgwụ kenyere ogbenye mgbasa ke ụbụrụ, ọrịa nke aka na ụkwụ, tinyere ha apịajighị apịaji, ọrịa nke urogenital usoro, polyneuropathy na microangiopathy.

Nicotinic acid nwere ndị na-esonụ contraindications: hypersensitivity ọgwụ, gastric ọnyá afọ, mgbu, gout, glaucoma, hypotension, ụmụ n'okpuru afọ abụọ. Ọzọkwa ọma iji nke a ọgwụ maka ọrịa nke ọdịdị ihu akwara, afọ, enterocolitis, trophic na nonhealing ọnyá ogologo oge.

Nicotinic acid nwere ndị na-esonụ mmetụta: flushing nke anụ, nācha ọbara-ọbara nke anụ ahụ, akọrọ mucous membranes nke anya na akpụkpọ, nakwa dị ka arrhythmia, dizziness, ọgbụgbọ na vomiting, pruritus, myalgia, hyperglycaemia, paresthesia. All ndị a phenomena pụrụ hụrụ mgbe na-ewere nnukwu doses nke ọgwụ. Ọ bụrụ na vitamin eyi na-eji maka a ogologo oge, e nwere ike ịbụ imeju dystrophy, ọdịdị ihu flushing, asthenia, dizziness, isi ọwụwa, na-abawanye nke AST, ALP na LDH ke iyịp.

Jiri ọgwụ mgbe a nri na ndị na-esonụ Dosages: okenye na - iri-na-ise milligrams kwa ụbọchị, ụmụ tọrọ afọ abụọ - ruo iri abụọ milligrams kwa ụbọchị.

Ọ ga-eti na nicotinic acid a na-eji na-ekwesịghị na Nchikota na anticoagulants na antihypertensive ọgwụ ọjọọ. Na nke ọ bụla, mgbe eji na ndị ọzọ ọgwụ ọjọọ eme ihe kwesịrị ịkpọ a ọkachamara.

Ọzọkwa, site na iji nicotinic acid ga-guzozie eguzozie nri (ngwaahịa nwere methionine) na mgbe nile na-akara nke imeju ọrụ. N'ihi na mma absorption na eriri afọ tract na-atụ aro ka na-aṅụ mmiri ara ehi nkwadebe.

N'ihi ya, nicotinic acid, nke ndu kọwawo n'elu bụ ihe dị oké ọgwụ maka igbochi na ọgwụgwọ nke ọtụtụ ọrịa. Ọ na-ewe akụkụ ke metabolic na oxidative Filiks na-erukwa ke idem, dị ka nke ọma dị ka na usoro nke na metabolism.