The ọgwụ 'Divigel'. ntụziaka

Nkwadebe "Divigel" - transdermal mmanya dabeere jel nwere a sịntetik analogue nke eke estradiol yiri ya (estradiol) ndu ọrụ. Usoro nke ihe nke ọgwụ ahụ yiri nke ndị ọnụ na estrogen-nwere preparations. Na-eji ọgwụ "Divigel" iji wulite endometrium.

The nkwadebe ụgwọ enweghị estrogen, na-ebelata ịdị njọ nke ọrịa metụtara na menopause na ovariectomy.

Na-agbanwe agbanwe na ojiji nke ọgwụ ọjọọ, "Divigel" na progestagen maka na ọtụtụ ndị inyom bụ mgbe menstrualnopodobnoe agba ọbara, oge nke nke nkezi nke ise ma ọ bụ ụbọchị isii. Malite na-agba ọbara, na-emekarị n'oge izu nke ikpeazụ dose of progestogen. Minor ntọhapụ a kọrọ na 4-5% nke ọrịa. N'afọ mbụ nke ọgwụ na 3-5% nke ndị inyom nwere amenorrhea.

Mgbe a transdermal (akpụkpọ) itinye estradiol ọnụ na medroxyprogesterone acetate a ojuju na ngụkọta cholesterol egosi.

Mgbe ngwa ka akpụkpọ mmanya anwụ na-amịrị. Estradiol na-ngwa ngwa etinye obi gị dum na-abatakwa systemic mgbasa. Ime ọgwụ "Divigel" na mpaghara 400 200 sq. cm (hà ebe nke otu ma ọ bụ abụọ aka), na-enweghị mmetụta na penetration ego nke nọ n'ọrụ mgwa ke n'ọbara. Otú ọ dị, mgbe etinyere a ọzọ ọtụtụ ogo absorption ngalaba nwere ike ịdị iche iche.

a ụfọdụ ego nke estradiol na-akwakọba na adipose subcutaneous anụ ahụ, site na nke ọ nwayọọ nwayọọ na-abanye n'ọbara iyi. Transdermal ngwa-enye gị ohere iji zere ida nke mbụ ngafe nke ọgwụ "Divigel", ke akpa ngafe site imeju. Ya mere fluctuations na plasma estradiol etoju ndị na-erughị akpọ mgbe eji ọgwụ ka tụnyere onu preparations.

Pụtara "Divigel" ntuziaka na-atụ aro maka ọgwụgwọ nke menopausal syndrome, nke e mere site ovariectomy ma ọ bụ menopause, nakwa dị ka ikwado ọnọdụ mere site estrogen erughi. Ọzọkwa, nkwadebe na-egosi dị ka isi mgbochi nke osteoporosis.

The onunu ogwu nke ọgwụ ọjọọ, "Divigel" nduzi aro mwube n'otu n'otu. Dị ka a n'ozuzu na-achị, inye 0.5-1.5 milligrams kwa ụbọchị. The onunu ogwu nwere ike ịgbanwe site dọkịta. The ọgwụgwọ N'ezie nwere ike na-aga n'ihu ma ọ bụ cyclical.

Mgbe ihe na-emebibeghị akpanwa ọgwụgwọ na "Divigel" ntuziaka na-atụ aro a okirikiri mgbe na-ewere progestin iri ma ọ bụ iri na abụọ ụbọchị ọ bụla okirikiri (maka mgbochi nke hyperplastic Filiks ke endometrium). On ẹkụre a N'ezie nke menstrualnopodobnoe ọbara ọgbụgba kwesịrị ime.

Mgbe ihe akp ma ọ bụ ruo ogologo oge eriri akpa nwa ọbara ọgbụgba aghaghị ịmata ihe kpatara ya. Cycle oge na postmenopausal ọrịa nwere ike ịbụ ruo ọnwa atọ.

The onunu ogwu nke ọgwụ ọjọọ, "Divigel" ntuziaka na-atụ aro ka ete ke ala afo ma ọ bụ n'ọrụ na ike ebe ke kiet ke otu ma ọ bụ abụọ aka, nwetụ ekpe na nri n'akụkụ. Na etinye ọgwụ ga-enye idebaihe maka a nkeji ole na ole.

Nkwadebe "Divigel" contraindicated na-agafere, atụmatụ ma ọ bụ ike ara cancer, estrogen-dabere cancer (endometrial cancer, n'ihi na ihe atụ), mmamiri bleedings nke na-amaghị na okike. Ekwela idepụta ọgwụ ma ọ bụrụ na untreated hyperplasia nke endometrium, bufee thromboembolic akpa ume embolism ma ọ bụ miri emi akwara thrombosis, myocardial infarction n'ime ikpeazụ afọ abụọ, re thromboembolism. Contraindications gụnyere nnukwu ma ọ bụ ala ala ọrịa imeju, hypersensitivity, lactation. Ọgwụ "Divigel" Pregnancy nwekwara na-adịghị kenyere.

Tupu iji ọgwụ kwesịrị ịkpọ na dọkịta chọpụta niile kwere omume mmetụta nke ọgwụ.