Norma-alụso ọrịa ọgụ megide TPO nwanyi: akpata na ọgwụgwọ

The thyroid gland emeputakwa homonụ na-enye uche na nke anụ mmepe, ibu nke ahụ ahụ, regulates ọnụego nke metabolism ke idem. Ozu synthesized site ọtụtụ homonụ nke nwere a nkịtị aha - thyroid. Thyroid dysfunction akpali oké nsogbu ke idem. N'ihi na n'oge nchọpụta nke daa ọrịa nyochara na-ekpebi ma ọ bụ karịa nkịtị alụso ọrịa ọgụ na TPO n'ihi na ndị inyom na ndị ikom na ahu.

Gịnị ka okwu ahụ bụ "-alụso ọrịa ọgụ na TPO"?

TPO - enzyme synthesized site thyroid gland, a na-akpọ thyroid peroxidase ma ọ bụ microsomal peroxidase. TPO abuana ke kpụworo thyroid homonụ na Jeremaya mere bụ ihe dị mkpa antigen ke idem. Na pathologies nke dịghịzi na endocrine usoro thyroperoxidase ọdịnaya Ịchọpụta Otú Nsogbu akpata. N'ihi ya, na-amụ ihe nke ndị akacha eji bụ ihe dị otú dị ka a "nkịtị TPO-alụso ọrịa ọgụ na ndị inyom na ndị ikom na" rụrụ a ọgwụ ule iji chọpụta ọrịa ahụ.

-Alụso ọrịa ọgụ na TPO - a protein okụre (immunoglobulins) synthesized na ụmụ mmadụ na-anaghị ekwe nke dịghịzi usoro. N'ihi ya, ha na-amalite ịghọta na enzyme thyroid peroxidase dị ka a mba ọzọ ahụ. N'okpuru ihe nke-alụso ọrịa ọgụ na enzyme ya ọrụ mbelata sharply, mmọdo guzobe thyroid hormone nke ọ na-ekere òkè na-kwụsị. N'ihi ya, na ibu ihe TPO na-ebibi, nta iche nke thyroid homonụ. Uto-alụso ọrịa ọgụ na TPO eduga dysfunction nke gland. Ya mere ọrịa na hypofunction ikpo a ọbara ule iji mata ma antibody ka TPO ọnụego karịa. Women na ụmụ na-enwekarị elu ụkpụrụ, ka ndị mmadụ na ọnụego nwere ike ịbụ elu karịa eke.

Norm-alụso ọrịa ọgụ na TPO

The eke ọnụego nke-alụso ọrịa ọgụ na thyroid peroxidase nwere otu uru niile ìgwè ọmụmụ. N'ihi ya, analysis of-alụso ọrịa ọgụ na TPO ọnụego n'ihi na ndị inyom na ndị ikom nke dị iche iche afọ bụ 35 IU / ml. N'ihe banyere ebe n'elu akụrụngwa nkeji 35, ọ ga-rụrụ ụka na thyroid immunoglobulins nwere a-ezighị ezi mmetụta. Ọ ga-kwuru na 10% nke e nyochara inyom nwere elu fọrọ maka norms, ma ọ bụ a nta karịa nke-alụso ọrịa ọgụ, na thyroid gland ọrịa na-adịghị akara. Ya mere, inwale nke a mma dị mkpa na njikọ na n'ihu ule na ọmụmụ ahụ.

Antecedents na-esi nke na-azụ-alụso ọrịa ọgụ na TPO

Kpụ ọkụ n'ọnụ mmepe nke-alụso ọrịa ọgụ megide thyroid peroxidase na-adị mgbe ndị dịghịzi usoro na-amalite ibibi ha thyroid mmiri. N'otu oge ịzụlite dị iche iche pathologies:

• mbufụt nke prostate - subacute na-adịghị ala ala (latent) thyroiditis;
• hypothyroidism - a-enweghị nchịkwa na usoro na-amalite na a erughi nke thyroid homonụ, nke na-eduga ndị ọzọ ọrịa nke endocrine akụkụ. Na ndị inyom, ọ na-eduga ná dysfunction nke mmekọahụ glands na ibu oké ibu;
• uto nke ahu - asị ibe goiter. Ọ bụ na ya pụta nke a enweghị thyroid homonụ na ayodiin erughi.

E nwere mgbe, mgbe karịa ọnụego-alụso ọrịa ọgụ na TPO nwanyi mgbe na-amụ nwa. Imebi mere site rearrangements nke dịghịzi usoro na endocrine glands n'oge ime. Nke a na onu nwere ike onwe rue a ọnwa ole na ole, ma ọ bụ mgbe ọ dị mkpa na-ekenye endocrinologist ọgwụgwọ siri na dysfunction bụghị ghọọ a na-adịgide adịgide ụdị.

Egosi immunoglobulins ka TPO nwere ike gafere ọnụego ọzọ autoimmune ọrịa na ndị na-abụghị thyroid ọrụ, n'ihi na ihe atụ n'okpuru lupus erythematosus, scleroderma.

Subacute thyroiditis na latent

The causative gị n'ụlọnga nke subacute thyroiditis a na-ewere a virus. Mgbe n'ịnwụ elu akụkụ okuku ume na tract-efe efe na ụmụ mmadụ echekwara adịghị ike, malaise, apụta agafeghị oke mgbu n'olu, inyịme ka azụ nke isi na agha na kawanye njọ site mbịne isi. N'ozuzu, picture bụghị nnọọ akpọ, ya mere ha nwere ike na-izu tupu ọ na-enyo enyo na mara ezi akpata ọrịa na-ogbenye ala nke ahụ ike.

Na nwayọọ mgbe, mgbaàmà na-tutu amama na ọrịa na-anata aspirin. Na ọzọ siri ọ na-achọ na ojiji nke glucocorticoids. The mkpali usoro na subacute thyroiditis wee dịruo ọtụtụ ọnwa, ma n'ozuzu a benign, na mgbe gland kpamkpam weghachiri eweghachi.

Mgbe zoro thyroiditis bụ ihe nkịtị na-abawanye na ọnụego nke-alụso ọrịa ọgụ na TPO na nwanyi. Na-akpata ọrịa, na-e kwuru na. Symptomatology owụt nwayọ: nta ngosipụta nke hyperthyroidism na a nta na-abawanye na cancer. Against ndabere nke ọgwụgwọ nke hyperthyroidism, ndị a mgbaàmà akwụsị n'ime 2-5 ọnwa. Otú ọ dị, ọtụtụ ndị ọrịa nwere Ugboro ugboro nke ọrịa, na ike na-amalite-agụghị oké kọwaa na ọ bụ ngwọta hypothyroidism.

Autoimmune thyroiditis (Hashimoto si thyroiditis)

N'ọnọdụ ka ukwuu, ihe na-akpata ọgba aghara nke thyroid gland jikọtara ọrịa ndị dị ka autoimmune thyroiditis. Mgbe ọrịa a na-hụrụ exceedances nke-alụso ọrịa ọgụ na TPO nwanyi mgbe afọ 50. Ndị kasị dị ịrịba ediyarade nke ọrịa - goiter. Ọzọkwa, izugbe contours nke prostate na-azọpụta, ma ụfọdụ asymmetry nwere ike hụrụ na ụfọdụ. Nke nta nke nta, na mmepe nke enweghị nchịkwa mgbanwe ara anụ ahụ ịzụlite hypothyroidism onu. Mgbe ụfọdụ, n'otu oge na ihe ịrịba ama nke Hashimoto si thyroiditis, e mgbaàmà nke ili 'oria. Nke a bụ ihe kasị mgbagwoju anya banyere thyroiditis.

The ọrịa bụ amenable ọgwụgwọ ma ọ bụrụ na achọpụtara na n'oge ogbo, ubara ọnụego nke mgbochi TPO na nwanyi. Ọgwụgwọ nke pathologies a rụrụ iji ịwa usoro, hormone nnọchi ọgwụ, nakwa dị ka ndinọ antiinflammatories.

Ụdị hypothyroidism - myxedema

Erughi nke thyroid gland, bụ nke a na-egbu oge nke metabolic Filiks ke idem, na-akpọ myxedema. Ọtụtụ mgbe a na ọrịa na-emetụta ndị inyom. The daa ọrịa e ji ala ahu okpomọkụ, onye na-adịghị mmeghachi omume mpụga stimuli, onye na-adịghị ekwu okwu, mgbe nile lethargy, acha akpụkpọ. The mbọ na akpụkpọ na-thickened. E nwere onye na-arụsi ọrụ ike na ọnwụ nke ntutu isi na nku anya. Women myxedema emee na njikọ na ovarian hypofunction, ọrịa shuga na ibu oké ibu.

Ka eso hypothyroidism na ọrịa na usoro ọbara ji erugharị: mkpụmkpụ nke ume, ibelata obi ọnụego, ala ọbara mgbali, ngwa mmepe nke atherosclerotic mgbanwe ọbara arịa, gụnyere ihe nile nke n'obi na ụbụrụ. Mgbe ndị dị otú ahụ ihe mgbaàmà, ọ bụrụ na ọ bụghị ngwa ngwa mepụta eru ọgwụgwọ, yikarịrị ịzụlite obi ọdịda.

Nchoputa na ọgwụgwọ nke myxedema

Myxedema nwere a na-egbuke egbuke mgbaàmà na-ewe ebe a latent ụdị, n'ihi ya, ọ na-esi ike nchọpụta. Ọ bụrụ na ị na-enyo a ọrịa ọ dị mkpa itinye a eru ọkachamara endocrinologist.

Nzọụkwụ na-esonụ ga-a quantitative ọmụmụ nke larịị nke secretion nke homonụ. Ọzọkwa, ndị ọzọ na-achọpụta ọrịa usoro nwere ike na-kenyere: ọmụmụ nke size na Ọdịdị nke thyroid gland; amụ ya ọtọ ikike, na organism na-ndinọ redioaktivu (kpọrọ) na ayodiin a hụrụ, osisi ike nke na ọ banye dị iche iche nke gland. Mgbe ụfọdụ, a biopsy a rụrụ na - samples maka laabu ule mikrokusochka prostate anụ ahụ.

Ozugbo nchoputa na-rụrụ mmiri ọgwụ ọgwụ. Ọtụtụ mgbe, ndị mgbaàmà kpamkpam tutu amama mgbe ewere thyroid hormone na Erere ụdị.

Elu-etoju nke-alụso ọrịa ọgụ na TPO na ime

N'oge ime, e nwere ike n'elu nbata-uzọ nke-alụso ọrịa ọgụ na TPO na nwanyi. The egosi bụ na ọ dị mkpa, ọ bụrụ na nnọọ ibu nke thyroid gland na, mmọdo, nwere ike dịkwuo larịị nke pituitary hormone - TSH, nke akara njikọ nke thyroid homonụ. Na nke a, na ọdịnaya nke ikpeazụ na-anọgide na nkịtị.

Antibody ule na-enyere aka ịmata nwaanyị latent hypothyroidism, nke nwere ike ime n'oge ime, n'ihi na oge a nke thyroid enwe oké nchegbu. Mụbara ọnụego immunoglobulins ọnụ na onye na-abawanye nke TSH egosi mmepe nke prostate dysfunction na ndị inyom na na ẹdude ize ndụ nwa, dị ka enweghị hormone na-emetụta ya mmepe. Ke idaha emi, iji gbochie nwa ebu n'afọ na ọnwụ, ọmụmụ nke nwa ọhụrụ na abnormalities ime nye iwu mmiri ọgwụ ọgwụgwọ.