Ntuziaka "Gonal-F." Description of nkwadebe, contraindications, analogs na reviews

Otu n'ime ndị nkịtị ụzọ nke infertility ọgwụgwọ bụ na-akpali ovulation. N'ihi ọtụtụ ihe àkwá adabara njikọta, ọ dị mkpa na-akpa àgwà a pụrụ iche tupu aṅụ ọgwụ. "Gonal-F" a na-ewere otu n'ime ndị kasị dị irè ọgwụ ọjọọ eme na mpaghara ebe a. Ntuziaka "Gonal-F" ike na-atụ aro ọgwụgwọ n'okpuru ike ike na-elekọta.

Description of

Onye ọ bụla maara na enweghị ovulation ime ike ime. Ya mere, ọtụtụ n'ime ndị ngosi mmekọahụ, chere ihu dị otú ahụ a siri ike nsogbu ga-edozi na mmalite na na vitro Fertilization. The ịga dibịa ga-akpa mepụta a ọgwụ nnyocha, bulie kwekọrọ ekwekọ atụmatụ nke usoro na ihe kwesịrị ekwesị preparations.

The kasị mma ma dị irè ngwá ọrụ na-dabeere na follicle na-akpali akpali hormone - FSH (recombinant), nke bụ maka na maturation nke follicles na nwanyi. Ntuziaka "Gonal-F" na-akọ na ọgwụ bụ nke a, Atiya, na usoro nke edinam bụ dị ka nso eke FSH. Ịzụta ọgwụ na na ndenye ọgwụ nke dọkịta.

egosi

Drug ina ke gynecological ubi na e kenyere mgbe rụọ ọrụ ibu nke follicles. Egosi maka ojiji "Gonal-F" nwere ndị na-esonụ:

• Enweghị ovulation na unsatisfactory N'ihi na etinye "Clomiphene".
• Polycystic ovarian syndrome (daa ọrịa metụtara mmiri ọgwụ ọrịa na-eme ka malfunction nke ovaries).
• The mkpa mmetuta nke multiple follicles maka IVF.

Ọtụtụ ọmụmụ ọgwụ nwere enen ndị nrụpụta nke ọgwụ mgbe ọ dị mkpa na mmepe nke multiple follicles na usoro nke ovarian hyperstimulation (achịkwa). E guzobere ya na-arụsi ọrụ ike mgwa na-akwalite uto nke follicles, ma si otú ukwu ebelata ihe ize ndụ nke ovarian hyperstimulation.

Ngwa maka ndị ikom

Mgbe ndị na-abụghị nnabata ya na nkiti ọrụ nke nwoke gonads nke spermatogenesis usoro - guzobere na mmepe nke spam - kụrie. Follicle akpali akpali hormone dị mkpa maka "na-amalite" nke usoro a, nke dịruru 75 ụbọchị. Ịchọpụta enweghị nchịkwa ala-ekwe omume nanị mgbe Itie ọgwụ nchọpụta nsogbu na nnyefe nke semen.

Mmalite (ma ọ bụ weghachi) nkịtị guzobere nwoke mmekọahụ gametes mgbe ụfọdụ na-ewe ogologo oge karịa a usoro yiri na nwanyi. N'ihi na a mma n'ihi omume ga-esoriri n'ụzọ zuru ezu na-atụ aro andrologist. Ị ga-esoro a pụrụ iche nri, enye ojiji nke mmanya na nicotine. Ọ bụ amanyere bụ iwu inye pụrụ iche preparations. Ntuziaka "Gonal-F" na-egosi na ọgwụ ike ga-eji welie spermatogenesis na ndị ikom na ndị nwere congenital ma ọ bụ enwetara hypogonadism. Agwọ kwesịrị n'okpuru elekọta ya mgbe nile nke a ọkachamara nwere ahụmahụ na ọgwụgwọ nke infertility.

ọgwụ

Active akụrụngwa nke ọgwụ eme follitropin Alfa - a umi na-akpali uto nke follicles na ụmụ nwanyị na-enwe nsogbu hypothalamic-pituitary usoro. The bioavailability nke ọgwụ mgbe ndinọ subcutaneously bụ banyere 70%.

Active mgwa amalite imubanye na organism mgbe ugboro ugboro ochichi. N'oge mbụ 3 ụbọchị hụrụ atọ dịkwuo ịha ịta nke follitropin Alfa, nke na-amalite mkpali usoro.

Inyeaka mmiri dị na ọgwụ nke sodium hydroxide na hydrogen phosphate dihydrate, phosphoric acid, methionine, sucrose, polysorbate 20.

ntọhapụ Ụdị

"Gonal F" na-arụpụta ihe Italian na-emepụta ọgwụ na ụlọ ọrụ "Industry Farmasyutika Serono SpA". Ụdị tọhapụ gị n'ụlọnga - ngwọta maka subcutaneous injection na lyophilisates maka mmiri mmiri.

The ndụdụ n'ụdị itienna nwere ike ibu 0,5, 0,75 na 1.5 ml. The kasị ala dose kwekọrọ 22 micrograms nke follitropin Alfa (300 IU), ọkara - 33 mg nke nọ n'ọrụ mgwa (450 IU). The kasị ibu ego nke nọ n'ọrụ gị n'ụlọnga ndị e dere na 1.5 ml - 66 micrograms ( "Gonal-F 900"). The price nke ọgwụ na-adabere na ịta nke nọ n'ọrụ umi.

Pen nwere a pụrụ iche dispenser na ọnụ ọgụgụ, na-enyere gị aka ịchịkwa dose. Na nke a n'ụdị na nkà mmụta ọgwụ na ịzụta kasị uru ekele dị iche iche Dosages. The uru nwere ike ekewet, na ọ dịghị mkpa maka nkwadebe nke a ngwọta n'ihu onye ọ bụla ogwu ogbugba.

Lyophilizate maka nkwadebe nke ihe ngwọta maka ọgwụ E jiriwo mmiri mmiri n'ihu onye ọ bụla aghụghọ. The chọrọ onunu ogwu nke tupu wepụtara a ọkachamara ka onye ọ bụla ikpe.

Olee otú ọgwụgwọ nke "Gonalom-F"?

Na enweghị ovulation ọgwụ amalite n'izu mbụ nke ịhụ nsọ okirikiri, nyere mgbe menses (ụfọdụ na o kwere omume ugboro ndiiche). The usoro nke mmalite ga-emejuputa atumatu n'okpuru akara nke ultrasound ọmụmụ, nke-enye gị ohere ịchịkwa size nke follicles. Malite dose - 0,13-0,25 ml ọgwụ "Gonal-F 75". Price ngwọta nwere 5.5 mg nke follitropin Alfa, bụ nke kasị ala na bụ na gburugburu 110 rubles. Dịkwuo dose n'elu 1-2 izu na 225 IU (kacha).

Ọ bụrụ na n'ime otu ọnwa ọgwụgwọ adịghị enye ezi ihe, usoro ọgwụ ga-kwụsịrị. mbụ onunu ogwu ga-amụba maka inwekwu ọgwụgwọ.

Mgbe ọ dị mkpa ka na-achịkwa ovarian hyperstimulation ọgwụ na-ndinọ na a onunu ogwu nke 150-225 IU. The kacha kwa ụbọchị dose ekwesịghị gafere 450 IU. Agwọ-amalite na 2-3 ụbọchị nke ịhụ nsọ okirikiri. Site n'enyemaka nke ultrasound ọkachamara ga-nyochaa uto nke follicles. Na oge nke ọgwụgwọ nwere ike si 5 ụbọchị 20. Mgbe ikpeazụ infusion, 48 awa ka e mesịrị, ntụtụ mmadụ chorionic gonadotropin.

Ndị ikom na-enwe nsogbu na usoro spermotogenez na-egosikwa mmalite. "Gonal-F" na nke a na-eji na Nchikota na mmadụ chorionic gonadotropin. Na mbụ ọgwụgwọ Usoro bụ subcutaneous ogwu ogbugba nke ọgwụ ugboro atọ n'izu (dose 150 IU). Duration nke ọgwụ kwesịrị dịkarịa ala 4 ọnwa, mgbe nke a nwoke kwesịrị ka a na-enyocha. Na obere ma ọ bụ ọ mma na-arụpụta nke ọgwụgwọ nwere ike ịgbatị na ọnwa 18.

dosing

The mbụ ntụtụ ọgwụ kwesịrị a ọkachamara na a ọgwụ. Ebe gwara, n'ọdịnihu ọrịa nwere ike iji pen na-eme ka a ogbugba, "Gonal-F." Ga-akpa ga-emehe ye ntuziaka ka ọgwụ.

Ndị na-esonụ nwere ikwu maka ndị ụlọrụ nọọrọ onwe ojiji nke ọgwụ:

1. Tupu ịma, "Gonal-F", ga-akwọ aka juputara na ncha na mmiri na ikekwe n'ihu esichara antiseptik.
2. Akadiahade na ọcha n'elu chọrọ ihe: pen ntụtụ, mkpọ ntụ ntụ na mmiri ogwu ogbugba, mmanya swabs.
3. Ọ dị mkpa iji dozie pen, wepụ okpu, setịpụrụ chọrọ onunu ogwu na itinye na agịga.
4. Lyophilisate (powder) jiriwo mmiri maka ọgwụ site ewebata mmiri mmiri n'ime vial na a akọrọ umi. The roba cover ga-mgbapu agịga na-emeghe a karama ọ dịghị mkpa. The mmiri mmiri ga-ẹkenam nwayọọ nwayọọ.
5. Ọ bụ pịa n'ime ikuku ntụtụ ruo mgbe achọrọ dose, inserting a agịga n'ime mkpọ na a ngwọta nke (mbụ n'elu si n'ala zuo), ịme ikuku na pịa chọrọ ego nke ọgwụ.
6. The ntụtụ kwesịrị ikuku egosipụta. Iji bibie ha, mkpa ka enweta gị na mkpịsị aka na mgbidi nke ntụtụ na-egosipụta ime ka top. Mgbe ahụ, ọ dị mkpa iji sọ plunger na nyak ngafe ikuku.
7. Skin e kwesịrị ihe antiseptik (mmanya) na ọgwụ na saịtị.
8. The ọgwụ na-eme subcutaneously na 45 ma ọ bụ 90 degrees. Sharply pịa plunger adịghị mkpa. The ọgwụ ga-ndinọ nwayọọ nwayọọ.
9. N'ihi nlekọta "Gonal-F" via ntụtụ itienna bụ zuru ezu iji pịa mmalite button. The agịga dị na ngwaọrụ dị gịrịgịrị, ma obere, otú ahụ mgbu nwayọọ ma ọ bụ fọrọ nke nta na-anọghị.
10. Mgbe ọgwụ ndị a na saịtị nke ọgwụ ga-esonyere a owu swab tinye ke nje.
11. Disposable ntụtụ tụfuo mgbe usoro.
12. Na agịga-ntụtụ ịṅụ ga-ewepụ, na-etinye na okpu. N'ihi na ndị ọzọ aghụghọ bụ mkpa na-eji a ọhụrụ agịga, nke-abịa zuru ezu na ọgwụ.

mmetụta

Nkwadebe "Gonal-F" nwere ike ime ka mmetụta n'oge ọgwụgwọ. Ụfọdụ ụmụ nwaanyị kwuru na-esonụ mgbaàmà:

• Omumu usoro - ọtụtụ mgbe ịzụlite ovarian cysts.
• Na-ezighị ezi mmetụta nke ọgwụ ọjọọ nwere ike na-emetụta akụkụ nke digestive tract. Ọ na-kwupụtara ọdịdị ọgbụgbọ, vomiting, afọ ọsịsa, ahụ erughị ala na ihe mgbu na afo.
• The ọgwụ saịtị ahụ nwere ike ime ozizi ma ọ bụ nācha ọbara-ọbara nke anụ ahụ.
• ikpe nke nfụkasị Jeremaya bụ nnọọ obere: ọkụ ọkụ, itching, ike iku ume, ihe ọkụ ọkụ.
• Na akụkụ nke Central ụjọ usoro - nwere ike ịghọ ndị ọzọ Ugboro isi ọwụwa.
• Dịkarịa ala mgbe e nwere otu nke na-ezighị ezi mmetụta na obi usoro (thromboembolism).

Ntuziaka "Gonal-F" na-egosi na ndị mmadụ na ọgwụgwọ nwere ike iyi ihe otutu, ubé ụba ahu aro. E nwere obere okwu nke varicocele, gynecomastia.

contraindications

The ọgwụ nwere ike mmetụta na ahu na mere ike ga-ndinọ enweghị tupu ọgwụgwọ. N'ọrụ umi na ndị ọzọ mmiri nwere ụfọdụ na-agaghị emeli mgbe eji. The dibịa ga-a n'ime akaụntụ na ịgbanwe ọgwụgwọ Usoro.

Ntuziaka "Gonal-F" dọrọ aka ná ntị na ọgwụ na-aju iji n'ihi na ndị mmadụ na-ekweghị ibe nọrọ ma ọ bụ hypersensitivity na bekee na Nwa. Na nke a, nwere ike ịzụlite oké anabata ma ọ bụ ndị ọzọ nsogbu. Ọzọkwa contraindications na-agụnye:

• Eriri akpa nwa ọbara ọgbụgba nke na-amaghị etiology.
• Oncologic daa ọrịa nke esịtidem kenwe.
• Sporadik ovarian cysts na mepụtara na ndabere nke polycystic.
• Pregnancy na lactation.
• Congenital abnormalities nke akụkụ, nke chere na ime.

A ọkachamara na-elebara niile comorbidities na dị ke ọrịa mere eme. Mgbe ụfọdụ, ọ dịghị mkpa na-eji ngwá ọrụ, "Gonal-F." Price ọgwụgwọ na-adabere na oge nke ọgwụgwọ na onunu ogwu nke ọgwụ, ma, ọbụna oké ọnụ ọgwụgwọ ka ndị na-atụ anya n'ihi na ndị dị otú ahụ pathologies dị ka eriri akpa nwa fibroids, akaghi menopause, mgbochi nke fallopian akpa.

Atụmatụ nke ngwa

Tupu ị na-ekenye a ọgwụ na-akpali ovulation ma ọ bụ spermatogenesis usoro, a dọkịta ọkachamara na ọgwụgwọ nke infertility, kwesịrị iduzi ọgwụ nchoputa di na nwunye, na-enyere achị si n'iru contraindications na mkpa ọgwụgwọ. Ọ dịkwa mkpa na onunu ogwu atụmatụ ga-arụnyere.

Ọrịa ndị na-ata mkpali "Gonalom-F" tupu IVF enwekwu inweta ime ejima. The dọkịta na iwu ji na-agwa ndị nwaanyị tupu mmalite nke ọgwụgwọ.

Imekotaotuugbo ojiji nke ọgwụ ndị ọzọ na-elekọta mmadụ na-emetụta uto nke follicles, pụrụ ịkpasu mmepe nke hyperstimulation. Kemgbe nke ọgwụ dị mkpa iji na-eduzi ultrasonic nchoputa na nyochaa uto nke follicles.

"Gonal-F": price na reviews

Italian ọgwụ na-akpali ovulation nwere ama ruo ogologo oge na kenyere maka ọgwụgwọ nke infertility na ma ndị ikom ma ndị inyom. Nke a bụ otu n'ime ndị kasị dị irè ngwaọrụ (ọtụtụ ndị dọkịta na-ezo aka na ya dị ka "arọ ogbunigwe"). "Gonal-F" gosiri ezi ihe ọbụna n'ebe ndị ọzọ mara n'aka dị ike. Ihe bụ isi na-achị ga-esochi ọrịa, dị zuru ike akara usoro nke merela agadi follicles na spermatogenesis.

Na ọgwụgwọ onunu ogwu nwere ike-agbanwe nta ma na a nnukwu ụzọ. The na-eri nke ọgwụ dịgasị iche n'ebe 1,100 rubles. ruo 16 000 rubles. ( "Gonal-F" 900 IU). Na mgbakwunye na ojiji nke oké ọnụ ngwaọrụ, o dikwa oke mkpa na-eso ụfọdụ iwu na ihe oriri na kpamkpam kpochapụ nri ratụ ratụ, ọkara okokụre ngwaahịa.

N'oge ọrịa, a machibidoro iwu ịṅụ mmanya, nke nwere a-ezighị ezi mmetụta na spam mmepụta, na-emetụta ndị pituitary gland na hypothalamus, ịkpaghasị metabolism mmekọahụ Steroid. Mụbara uche na spam na nicotine.