Ọgwụ "Fluorouracil": ntuziaka maka ojiji, nkọwa, mejupụtara, analogs na reviews

Cancer, dị mwute ikwu, e nwere ugbu a nke ukwuu mgbe. Kwesịrị ịdị, anyị nwere ike mbà, anyị ga na-alụ ọgụ a na ọrịa. Na nke ọ bụla na-ekwesịghị-emeso onwe ha. Enweghị ọkachamara enyemaka dị oké mkpa. The eziokwu na ụfọdụ ọgwụ ọjọọ nwere ike na-kenyere ọgwụ na a na-eji naanị na pụrụ iche Usoro. Na ọtụtụ mgbe, ndị dọkịta ji nye iwu ka a ọgwụ dị ka "Fluorouracil". Ntuziaka maka ojiji nke ọgwụ ga-setịpụrụ dịrị gaba n'ime ebe.

General e ji mara

Ya mere, n'ihu ọgwụ na-eji na oncology, dị ka nwere mgbochi akpụ mmetụta. Ọ nwere ike na-eso ná ndị antimetabolite. Ya bụ, umi dị mmiri mmiri, nwere ike budata akwụsịlata mgbanwe nke bekee n'etiti mkpụrụ ndụ.

"Fluorouracil" (ntuziaka maka ojiji na-mgbe na packaged na ọgwụ) nwere a dị mfe owuwu. Ọ na-agụnye akpali mmasị na mmiri na sodium hydroxide. Ma isi n'ọrụ akụrụngwa bụ fluorouracil.

Hapụ forms na atụmatụ nke ọgwụ

Ọ ga-kwuru na nke a na nkà mmụta ọgwụ nwere ọtụtụ iche-iche. Ọ bụrụ na ị chọrọ ya, "Fluorouracil" ntụziaka ntuziaka na-ekwu banyere ndị dị otú ahụ n'ụdị ya:

1. A mmiri mmiri ngwọta maka igba ogwu n'akwara ma ọ bụ intracavitary ochichi. Ọtụtụ mgbe ọ na-eme nke okenye 5% ngwakọta nke 5 ml ampoules. E nwekwara a lekwasị ngwọta nke a na enịm ke a 10 ml karama.

2. Ude. Ọ bụkwa na-emekarị 5% nke nke. Ọ na-eji na-emeso akpụkpọ ọrịa, e.g., Basile.

Ọ bụrụ na ị na-ahọpụta dị ka "Fluorouracil" ntụziaka ntuziaka nwere ndị na-esonụ ọmụma banyere n'ikuku na sekit na sekit:

- Kwa ụbọchị na-enweta 0,5 g / m. ma ọ bụ 12 mg / n'arọ. ọgwụ bụ karịa 5 ụbọchị. Mgbe na kwesịrị otu ọnwa ezumike.

- otu ugboro na 7 ụbọchị nke 0,6 g / m. N'ezie nke ọgwụ bụ banyere 6-10 izu.

- Yana ọzọ anticancer ọgwụ - 1st na 8th ụbọchị nke N'ezie nke 0,6 g / m.

Otú ọ dị, mgbe nile, onunu ogwu na usoro nke ochichi nke ọgwụ na-kenyere n'otu n'otu. Ọ niile na-adabere na n'ogo na na ogbo nke ọrịa, izugbe ala onye ọrịa, ọrịa ya dị ka nke ọma dị ka atụmatụ maka ọgwụ.

Liquid ike ga-ndinọ bolus ma ọ bụ infusion. Buru n'uche na ụfọdụ ọgwụ ndị na-e nyere onye ọrịa na njikọ na nke a, enye fluorouracil dose Mbelata site 20-30%.

Pharmacological mmetụta na na nkwukọrịta ndị ọzọ ọgwụ ọjọọ eme ihe

N'ihi ya, "Fluorouracil" (ntuziaka maka ojiji, a nkọwa nke nkwadebe ga-agụ site ndidi) na-enye mgbochi mkpali mmetụta ma na budata slows chemical mmeghachi omume nke ndị na-akwalite nkewa nke ịza mkpụrụ ndụ. Nke ahụ bụ, umi nkanka guzobe DNA.

Mmiri pụtara ngwa ngwa, akpụ ftoruridinmonofosfat. Ọ na-rapara na imeju maka banyere 20 awa. The ndọrọ ego akụkụ okuku ume na aka (60-80%) na akụrụ (7-10%, na-agbanweghi agbanwe).

Ọ bụrụ na ị mkpa iji "Fluorouracil" ntụziaka ntuziaka (akụkụ nke na nkà mmụta ọgwụ, anyị na-ama tụlere) na-ekwu na e nwere ụfọdụ bekee a na-apụghị jikọtara ha. Ka ihe atụ, sulfa ọgwụ ọjọọ, na phenylbutazone chere na kwuru n'aka. Ma Alfa-interferon na cytotoxic mmadụ, na Kama nke ahụ, na-amụba na mmetụta nke "Fluorouracil". Ọ ga-akpọrọ n'ime na akaụntụ na oru nke usoro onunu ogwu.

Rịba ama na ịgba ọgwụ mgbochi ọrịa nke ọrịa, n'ihi na ya ebelatawo dịghịzi usoro a ga-rụrụ bụghị tupu ọnwa 3 - a afọ.

Egosi maka ojiji

Ọ bụrụ na ị na-achọ "Fluorouracil", ntuziaka maka ojiji (ọgwụ ego na nkezi 3000-3990 rubles) agwa akụkọ ndị a ọgwụ ọnọdụ:

• Cancer nke mkpa ma ọ bụ ikensi, na nkọlọ na afo. N'ihi ya, ọbụna mgbe ọgwụ e nyere ogbo ma ọ bụ unresectable metastases.
• Primary imeju cancer.
• Ịza aza ọrịa nke ńsí eriri afo, ovary, nke ara, cervix.
• Cancer nke adrenal glands.
• Cancer nke prostate lesion.
• Kartsinoz ma ọ bụ penile cancer.
• Etuto ahụ na olu na isi.
• A precancerous ọnọdụ, na obere etuto ahụ.

Osụk site ọgwụ ike ga-eji ọbụna mgbe fungal anụ ọnya.

Gịnị na-na contraindications adị?

Kwesịrị ịdị, onye ọ bụla nke chemical nkwadebe pụkwara bara uru n'ihi na mmadụ nile. Na nke a, ihe nwere ụfọdụ contraindications.

• Kwa elu a uche na ụfọdụ mmiri nke ngwá ọrụ.
• Pregnancy na lactation. A ọgwụ nwere nnọọ na-egbu egbu utịp ke nwa ebu n'afọ. Ọ bụrụ na n'ikuku họpụtara n'oge ara, nwa si ara-ewe.
• Peptic ọnyá afọ ọrịa 12 duodenal ọnyá afọ ma ọ bụ na afo, bụ nke dị na nnukwu ogbo.
• Siri ike anaemia na Ugboro ọbara ọgbụgba ndị siri ike ma ọ bụ gaghị ekwe omume ka ọ kwụsị (hemophilia).
• Leukopenia.
• Mkpọchị gbasara akụrụ ọrụ ma ọ bụ a imeju.
• Health onye ọrịa tupu ndu ọnwụ.
• Kemgwucha ike ogo ike gwụrụ.

Ke adianade do, e nwere ụfọdụ na-agaghị emeli. Dị ka ihe atụ, na-elekọta nye iwu a ọgwụ ndị mmadụ na-ata ahụhụ site na shingles ma ọ bụ chikinpoksi. Ọ dị mkpa ka etinye uche pụrụ iche na-oru nke ọgwụ ma ọ bụrụ na onye ọrịa a na-ama na-ewere cytostatics.

Ekwe Omume mmetụta

Ọ bụrụ na ị na-kenyere a N'ezie nke ọgwụ dị ka "Fluorouracil-Lance 'ntuziaka maka ojiji nke ọgwụ adịghị si dị iche na mbụ e dere. A ajụjụ na-amasị ọtụtụ ndị ọrịa, na-mmetụta. The eziokwu na ha nwere ike mgbe ụfọdụ sie ike karịa ọrịa ahụ n'onwe ya. N'ihi ya, na-anata umi pụrụ hụrụ mmetụta:

• Mbenata ọnụ ọgụgụ nke leukocytes na platelet na ọbara.
• Nosebleeds, nke bụ ike ịkwụsị ya.
• Bịara ikiri ọhụụ, ngwa ngwa anya.
• Ọgbụgbọ, nke nwere ike mmasị na vomiting na afọ ọsịsa. Na nke a, ọgwụgwọ a ga-kwụsịtụrụ ma ọ bụ gbanwetụrụ.
• Peptic ọnyá afọ.
• Stomatitis.
• Ele Mmadụ Anya n'Ihu ma ọ bụ ngụkọta alopecia (nkwọcha).
• Ischemic obi ọdịda, arrhythmia, rịaworo, obi ọdịda, myocardial infarction, cardiomyopathy, thrombophlebitis.
• Mgbu na nọgidere na isi, mụbara adọka mmepụta, na egwu nke ìhè, mgbagwoju anya, ọnwụ nke nsụhọ doo anya.
• Dysarthria.
• The uto, gastric agba ọbara, nrekasi obi, anorexia na hepatic arụmọrụ.
• Mkpụmkpụ nke ume, ụkwara, bronchospasm.
• Abnormalities na omumu usoro: inyom - enweghị ịhụ nsọ, ndị ikom - azoospermia.
• hyperpigmentation nke anụ ahụ, nkụ na cracking.
• Urticaria, ọkụ ọkụ, dermatitis.
• Muscular adịghị ike na isonye na-efe efe nke dị iche iche iche iche.

Dị ka ị pụrụ ịhụ, nyere mmiri mmiri ma ọ bụ "Fluorouracil" ude, ntụziaka ntuziaka na i nwere doro anya, na-adị nnọọ ize ndụ ọgwụ ọjọọ. Ke adianade do, nnyocha ụfọdụ na-atụ aro a siri ike ga-ekwe omume nke toxigenic na carcinogenic mmetụta nke ọgwụ ahụ.

Ọnọdụ nke nchekwa ngwaahịa

Ya mere, ị na-ama natara a ọtụtụ ihe ọmụma na osụk gbasirila. Ugbu a, anyị kwesịrị ịtụle ihe e ji mara ya nchekwa. Ịbụ "Fluorouracil" ga-ke a gbara ọchịchịrị ebe. nchekwa okpomọkụ kwesịrị 15-25 degrees. N'ezie, ọgwụ kwesịrị nọ n'ebe iru nke ụmụ. Akpụkọta mmiri mmiri na-adịghị na ukwuu tụrụ aro.

Adị ndụ nke ọgwụ bụ 2 afọ. Mgbe ngafe nke ngwaahịa a enweghị ike na-oge.

E nwere mgbe ụfọdụ sedimenti na-egosi na ala nke vials. Na nke a emee mgbe ogologo oge nchekwa. Gbalịa ka ikpo mmiri mmiri na 60 Celsius na ike aka. Next jụụ umi 35 degrees. Ọ bụrụ na ndị ịkpali etisasịwo, na mmiri mmiri ghọrọ uzo ọzọ, ya mere, nkwadebe bụ njikere maka ojiji.

analogues na nkà mmụta ọgwụ

Ndị isi ihe bụ ihe mkpa ka ị mara tupu ewere "Fluorouracil" ọgwụ - ntuziaka maka ojiji. Nyocha ga-n'ekpere. Ị ga-ahụ mgbe e mesịrị.

Ọ bụrụ na onye ọrịa nwere ike imeli ya ịzụta ọgwụ, dọkịta nwere ike nye iwu ka analogues ya. Ha nwere otu Isi nọ n'ọrụ mgwa - fluorouracil. Ugbu a, e nwere analogues nke a ọgwụ:

1. "Fluor-uracil."

2. "Efundeks".

3. "EPF-Ricks."

4. "Fluoropleks".

5. "Fluratsil".

6. "ntụ ọka".

7. "Kveropleks".

8. "Timazin".

Nyocha

Ọ ga-kwuru na nkà mmụta ọgwụ na-eji ezi mgbe. Ọtụtụ ndị ọrịa kọrọ elu nrụpụta na-alụso etuto ahụ.

Otú ọ dị, ha na-ekwu, na ọnụ ọgụgụ buru ibu nke mmetụta: ọgbụgbọ, vomiting, isi ọwụwa, mgbagwoju anya na mbara igwe. Nke a abụghị ihe ijuanya, n'ihi na ọgwụ bụ ukwuu na-egbu egbu.

N'ihi ya, anyị nyere ihe ọmụma banyere ọgwụ "Fluorouracil": ntuziaka maka ojiji, price, reviews. Cheta na onwe aṅụ ọgwụ a, ị na-ekwesịghị. Jide n'aka na-hụ dọkịta. Ma ọ bụghị ị n'ihe ize ndụ imerụ onwe gị ọbụna karị. The ọzọ na a ziri ezi nchoputa naanị ike ịtọ a warara ọkachamara, mgbe nnyocha kwesịrị ekwesị. Nọrọ mma!