Ọgwụgwọ nke ehighị ụra nke ọma. hypnotics

Ọ bụla dị ndụ nke dị na-enwe mmetụta circadian rhythms. Karịsịa ndị a circadian dabere pụta ìhè mgbanwe site wakefulness-ehi ụra na azụ. Fọrọ nke nta niile n'ahụ Filiks na-emetụta a periodicity. Na aza ala nke a onye na-arụsi ọrụ ike mmekọrịta n'èzí ụwa. Ọkpara ya, nke a na mmekọrịta anaghị akwụsị, ma ọ na-ewebata a ọnụ ọgụgụ nke iche.

The peculiarity nke nkịtị n'ahụ ụra bụ na ọ na-ewe ebe nditịm na ụfọdụ ogbo. A onye ahụ gbasiri ike ụra, na-agafe na ogbo A, ma ọ bụ "ala wakefulness." Mgbe nke na-abịa na ogbo B, na latent oge nke na-ehi ụra, e ji backfilling na kasị elu elu bed. Na Nzọụkwụ C, na-ehi ụra onye nwere dịghị mmeghachi omume na-adịghị ike stimuli. Nzọụkwụ D e ji moderately oké ụra. Ụra miri emi ogbo kwekọrọ E. wee pụrụ iche ogbo tupu edemede. Ọ mgbe ụfọdụ so site ngwa ngwa anya mmegharị-ewere ọnọdụ, e nwere atony nke ọzọ striated muscle.

Nsogbu nke ụra eruba nwere ịrịba ọjọọ mmetụta na n'ozuzu anụ ahụ, echiche na inwe obi ala. Tupu pharmacology ka ogologo nwere a ọrụ ike a hypnotic mmadụ na-enwe ike ọ bụghị naanị ime ka iro ụra, ma na-enye a zuru N'ezie nke n'ahụ Filiks.

N'ihi na oge mbụ nsogbu a ka e merie n'etiti ndị ọkà mmụta sayensị nke iri na itoolu na narị afọ. Hypnotics malitere ya akụkọ ihe mere eme na sịntetik ọgwụ chloral hydrate. Ọzọkwa nyere ụra nkwadebe na calming mmetụta. Dream mere site chloral hydrate, nso na e ji mara ya na n'ahụ, ya oge ruru n'etiti isii na awa asatọ. Ma iji ya eme ihe mere ka iwe mmetụta na akpụkpọ mucous membranes, e nwere ọgwụ dependency. Mbenata uru nke chloral hydrate n'ihi na nke mmetụta emewo ka eziokwu na nke a ọgwụ bụ ugbu a ka a hypnotic na-adịghị mee ihe.

A ịrịba itunanya na search maka n'aka hypnotic edinam bụ ọdịdị na 1902 nke ọgwụ ndị na-emepụta nke barbituric acid. N'ihi na nke a chọpụtara, na German mmiri ọgwụ E. Fischer natara Nobel Nrite. Ma na nke a, irè nke nke nwere ọhụrụ ọgwụ ụra, E ji a ọnụ ọgụgụ nke mmetụta. Iji barbiturates dugara eziokwu na ụtụtụ, e nweghị uche nke ntatido na freshness, mgbe ụfọdụ pụtara ntakịrị n'ozuzu ike ọgwụgwụ, na-akpata na-ebelata ikike o nwere ịrụ ọrụ, na-akawanye njọ nke ọnọdụ.

The sixties nke iri abụọ na narị afọ nyere ụwa a ọhụrụ ìgwè nke ọgwụ ọjọọ - nkwekọrịta nke benzodiazepines. Ndị a na-agụnye "Diazepam", "Hlordiadepoksid", "Phenazepam" na ndị ọzọ. Ndị bekee bụghị naanị a ogwuura mmetụta, ma na-eme soothingly. Action benzodiazepine ọzọ n'ahụ na eke na-eru nso nkịtị ụra, ọ malitere ọtụtụ-eji na ọgwụgwọ nke na ehighị ụra nke ọma dị iche iche nke pụta ìhè.

Ma, ebe a bụ na-enweghị mmetụta nke ya na-adịghị mma ngosipụta, karịsịa, na okwu nke ọgwụ na nduzi, gosiri na ya siri ike ka nke barbiturates. Fọrọ nke nta niile ọgwụ ụra na-adịghị a ọgwụgwọ maka ehighi ura, ma choro ha n'ikuku site na akara nke dọkịta.

More na nso nso, ọgwụ e ji mee na ọgwụ na ahụ ike omume, a emepụta nke ethanolamine. Ọgwụ ụra "Donormil" ozugbo nile na Central na Western Europe na Middle East, wdg, Ọ ọbụna gụnyere a ìgwè nke ọgwụ ọjọọ na-ekesa na-enweghị a ọgwụ. Ịmịpụta "Donormil" dị ka n'ụdị ntekwasa mbadamba, ma ọ bụ dị ka effervescent mbadamba. Onye ọ bụla mbadamba nwere 15 mg doxylamine succinate, hypnotic na-adịghị rụrụ ke tụlee.

Taa, ọ bụ ihe kasị kwesị ekwesị usọbọ maka ehighị ụra nke ọma. Ọ na-adị mfe ewepụtara ahụ mmadụ. Mere site a ọgwụ nwere otutu ụra obshego n'ahụ ala.