Prothrombin index, ọnụego na uru

Prothrombin index, ọnụego nke bụ hà 95-105%, - bụ otu n'ime ihe na-egosi ihe e ji mara ọbara clotting. Blood clotting - a nnọọ mgbagwoju usoro nke a rụrụ na òkè nke a cascade nke pụrụ iche na-edozi na-akpọ coagulation ihe. The ebighị nke usoro a bụ na o kwere omume na ụzọ abụọ - esịtidem na mpụga.

Ọ prothrombin index e ji mara ndị ebighị nke coagulation site na extrinsic ụzọ. Ọ bụ dị ka ndị: mebiri nke ike n'ezi ihe nke anụ ahụ (ọnya) na-ekenyela na-akpọ anụ ahụ thromboplastin, a pụrụ iche protein ndị dị na niile ahụ arọ. Ọ na-akpalite a cascade mmeghachi omume nke tinye ọzọ clotting ihe (V, VII, na X, II, m), successively rụọ ọrụ ọ bụla ọzọ. Mee elu mee ala, a ọbara clot a kpụrụ na ọbara ọgbụgba akwụsị.

Nso ke prothrombin index

Clotting ihe na-guzobere imeju. N'ime ndị a, II, V, X bụ vitamin K-ndabere. Na enweghị vitamin ha njikọ na-akwusila. Ntem, e nwere imebi nke hemostasis. Ịmata prothrombin index, nke a maara ọnụego, dọkịta gị nwere ike:

1. Arụ Ọrụ Rate emetụgodị II, V, VII na X nwekwara clotting ihe
2. The ịdị ukwuu nke a na-egosi na-ekpe ikpe ndị ọrụ nke imeju
3. On saturation nke vitamin K
4. Izugbe ala nke ọbara coagulation usoro
5. Dị ka nke a na-egosi, ị nwere ike inyocha irè nke anticoagulant ọgwụ.

Dị ka akọwapụtara site na prothrombin index

Prothrombin index kpebisiri ike na capillary ma ọ bụ venous ọbara. Nke abụọ ahụ na-ebu ọnụ ọbara ẹka n'ime a ule tube ihe anticoagulant na a ruru nke 9: 1. Mee anticoagulant sodium citrate. Na laabu, ọbara na-centrifuged. Ihe plasma na-eji maka mkpebi siri ike nke prothrombin oge (pt). Norm MF bụ na a nso si 12 20 sekọnd, dabere na ọrụ nke thromboplastin eji na N'ezie nke mmeghachi omume na laabu.

Ịmata ọrịa pt, ị nwere ike gbakọọ PI, ie, prothrombin index, nke bụ norm dị iche iche laboratories nwekwara ike ịbụ a bit dị iche iche. Ọ bụ hà ruru px onye ahụ gbasiri ike ka a PV ndidi, ọtụtụ site 100:

PI = PV ike. / SA arịa ọrịa. X 100 (nkịtị 95-105%)

The adakarị pụtara PI

Na elu pt coagulation ma ọ bụ prothrombin onye norm nke 12 na 20 sekọnd na-shortened, na PI abawanye. Nke a pụrụ ịbụ n'oge ime, na a oke mmerụ mgbe ọbara na-abịa a ọtụtụ anụ ahụ thromboplastin.

Ọzọ, MF-abawanye na mbelata na a ọnụ ke PI clotting, dị ka n'ihe banyere congenital erughi nke clotting ihe, na oké ọrịa imeju, na a erughi nke vitamin K (nke nwere ike ime cholestasis, dysbacteriosis, na-akpaghasị gootu ọrụ). PI mbelata na ala fibrinogen ma ọ bụ a ọtọ nkwarụ, na syndrome DIC, na ọnụnọ nke bekee inhibit clotting.

Gịnị bụ INR

Ọgwụgwọ nke anọ anticoagulants ndammana ebelata prothrombin index. Ya norm nwere ike ịbụ ya na-ọ bụla laabu. Ya mere, iji na-enwe ike iji ya tụnyere ule pụta nwetara dị iche iche laboratories, ọ ẹkenam a etozu ule ndị dị otú ahụ dị ka INR. Nke a ngụkọta oge index. Ọ na-ekpebisi ike dabeere ruru nke prothrombin oge onye ọrịa, na nkịtị uru MF na ogo thromboplastin uche index (isi).

INR = (pt b nke / MF ọnụego) na ogo nke isi

Na onye ahụ gbasiri ike na INR na nso 0, 8-1,2.

Nke a na egosi na-eji na nlekota irè nke anticoagulants edinam. Na ọgwụgwọ nke anticoagulant mgbe coagulation na-ebelata (atụ mgbe ịwa obi) INR ga-amụba ka 2-3. Na-amụba INR clotting na-ebelata. The ruru n'etiti PI na INR bụ dị otú ahụ na a ọnụ na PI index ụba INR.