"Teopeka" (300 mg): ntuziaka maka ojiji, na-egosi, emeputa

Ndị na-arịa ụkwara ume ọkụ, maara otú mkpa oge iji nyere aka na bronchospasm. Mgbe ụfọdụ, ndị ziri ezi ihe na nke a siri ike ọnọdụ nwere ike ịzọpụta ndụ. A ịrịba ama ọrụ ime ka ndị mmadụ si akpa ume nsogbu na-akpọ bronchodilators.

Description of nkwadebe

"Teopeka" (300 mg), ntuziaka maka ojiji nke a na-egosi na nke a akwụkwọ bụ a na-acha ọcha mbadamba ploskotsilindricheskoy okirikiri udi, nke na-juru n'ọnụ ke mbukota ngwe. Isi nọ n'ọrụ mgwa nke ọgwụ bụ theophylline. Ya ịta na otu mbadamba nkume nke nkwadebe nke a ụdị bụ 300 mg.

Olee otú nke a na nkà mmụta ọgwụ?

Site ya pharmacological edinam nke theophylline, nke bụ a emepụta nke purine, nwere inhibiting utịp ke phosphodiesterase. The n'ọrụ mgwa nke ọgwụ nkanka kpọmkwem purine anabata, akpali Camp ìgwè ke anụ ahụ depots, lowers ikike ire ụtọ muscle anụ ahụ kpum, na-ebelata ego nke free calcium ion, nke akwaga site cell membranes.

Akara akpọ vasodilating mmetụta n'ikuku "teopeka" nkwadebe (300 mg). Ntuziaka maka ojiji na-akọwa na ihe onwunwe dị ka ihe mmetụta na elu ọbara arịa. Theophylline enwekwu ọbara site na gbasara akụrụ usoro, na-akwalite ntụrụndụ nke bronchial ezigbo muscle na ọbara arịa. Ọzọkwa, ihe nke nọ n'ọrụ akụrụngwa e ji dị ka nwayọọ mamịrị. Theophylline egbochi ntọhapụ nke bekee na ya, akpali iche adịghị anabata omume nakwa dị ka na-enwekwu nkwụsi ike nke poolu cell membranes. Ọ bụrụ na onye ọrịa hypokalemia ifịk umi-amụba ventilashion.

Theophylline enyere normalize ịrụ ọrụ nke akụkụ okuku ume na, rụọ ọrụ kwekọrọ ekwekọ center na ụbụrụ, dapụtara na a mma ọbara oxygen saturation, ọ mbelata ịta nke carbon dioxide. Drug "teopeka" akpali diaphragm, na-eme ya ka ebipụ. Ọ na-enwekwu ndị na-uru nke egosi mucociliary nwechapụ ọrụ amụba akụkụ okuku ume na intercostal uru.

Theophylline eduga nkịtị ọbara mikrotsirkullyatsiyu ebelata thrombus guzobere, kpọmkwem ihe na-akpata suppresses na eliminates aggregation nke platelet mkpụrụ ndụ. ọgwụ na-mma na oruru ọbara quality, enwekwu iguzogide deforming erythrocytes ihe.

"Teopeka" (300 mg), si otú mbenata ngụkọta mgbali na akpa ume mgbasa, na-ebelata-eguzogide na akpa ume vaskụla usoro. N'ihi ya, ụda olu nke akpụkpọ integuments, akụrụ na ụbụrụ mbelata. N'ihi nke na-anata theophylline akara mmalite nke akwara ọbara, mụbara gbasara obi ọrụ, na-abawanye nke myocardial pụtara mkpụrụ ndụ kwesịrị oxygen, quickens usu, ike nke obi contractions ụba.

Pharmacokinetics na pharmacodynamics nke ọgwụ

Mgbe onye ọrịa were Erere na theophylline, umi kpamkpam etinye obi gị dum na eriri afọ tract. Food ọṅụṅụ nwere mmetụta na ọnụego nke absorption nke ọgwụ, ma ogo absorption na nwechapụ anọgide na-agbanweghi agbanwe. Ebe ọ bụ na plasma protein ejikọ 40% nke nọ n'ọrụ umi. Theophylline metabolism pụtara na imeju site cytochrome P450.

Excretion nke metabolites emepụta na-arụ ọrụ n'ụdị via akụrụ, ma 10% nke ọgwụ na-tutu amama ke akpasarade ụdị. Ihe ụfọdụ nwere ịrịba utịp ke metabolism nke theophylline. Ịṅụ Sịga, na-ewere ụfọdụ ọgwụ, dietary àgwà, comorbidities, afọ, ike ime mgbanwe iji mgbanwe nke nọ n'ọrụ umi ke ahụ mmadụ. Mbenata nwechapụ nke theophylline a hụrụ na akpa ume edema, ọrịa imeju, COPD, na n'obi ọdịda.

Ònye pụrụ ịnabata ngwá ọrụ a?

E nwere ụfọdụ ọnọdụ nke a "teopeka" (300 mg). Ntuziaka maka ojiji na-akọwa ndị na-esonụ ọrịa:

• okpo bronchitis na-adịghị ala ala ụdị;
• ụra apnea;
• emphysema;
• ụkwara ume ọkụ;
• akpa ume ọbara mgbali;
• akpa ume n'obi.

Ọzọkwa, ọgwụ "teopeka" mma nzaghachi nke ike-etinyere na njikọ na ndị ọzọ ọgwụ ọjọọ eme ihe na ọgwụgwọ nke gbasara akụrụ edema okike. Ọrịa lee elu arụmọrụ nke ngwá ọrụ na ya anabata na maka ọgwụgwọ nke ọrịa na nke akụkụ okuku ume na usoro.

contraindications

Otú ọ dị, a ọgwụ ike ga-eji ọ bụghị mmadụ, n'ihi na nke ọnụnọ nke a ọnụ ọgụgụ nke ịdọ aka ná ntị si ego. "Teopeka" contraindications ndị dị ka ndị:

• hemorrhagic ọrịa strok ụdị;
• akwụkwụ na-adọ;
• agba ọbara si eriri afọ tract na akụkọ ihe mere eme;
• ọnyá afọ guzobere na digestive akụkụ;
• tachycardia elu severities;
• mgbali elu hypotension;
• hypersensitivity;
• mgbu, Bilie elu acidity;
• Children ruo afọ 12 na afọ.

Na ọnụnọ nke ọ dịkarịa ala otu n'ime ndị a ọrịamkpokọta ma ọ bụ ọnọdụ nke ọgwụ theophylline hapụ

mmetụta

E nwere nnọọ ihe a nnukwu ìgwè n'akụkụ-mmetụta si ewere "teopeka" nkwadebe (300 mg). Ntuziaka maka ojiji nke ha mbak na systemic ngosipụta:

• ọrịa nke ụjọ usoro: isi ọwụwa, dizziness, ụra n'ọgba aghara, erughị ala, inwekwu nchegbu na ogwe, ịma jijiji;
• dysfunction nke obi na ọbara arịa: tachycardia, arrhythmia, hypotension, mụbara ugboro ole nke rịaworo ọgụ, ụgha rịaworo;
• mebiri eriri afọ kwesịrị ịrụ ọrụ: ọgbụgbọ, gastralgia, vomiting, nrekasi obi, reflux, exacerbation ọnyá, afọ ọsịsa, na-ebelata agụụ;
• ngosipụta nke nfụkasị Jeremaya: akpụkpọ ọkụ ọkụ, ọkụ, itching;
• ndị ọzọ oghom ihe si na-ewere ọgwụ na-kwuru, sị: tachypnea, albuminuria, mụbara diuresis, ihe mgbu na sternum, hematuria, flushing, mụbara sweating, gipoglekemiya.

A, mgbazi nke dose ka ibelata mmetụta na-ebelata ma ọ bụ na-akwụsị kpam kpam.

Olee na-ọgwụ?

Pụtara site bronchitis, dị ka "teopeka" e kenyere naanị site ịga dibịa na ha onunu ogwu na-họrọ na n'otu n'otu. The nkezi, kwa ụbọchị Nome nhata 400 mg theophylline. Ọ bụrụ na onye ọrịa na-eburu ọgwụ ọma, mgbe ahụ, mgbe 2-3 ụbọchị si mbụ dose nke ịṅụ ọgwụ, olu mụbara site 25% na n'ihu site dọkịta ezi uche.

Mgbe e n'aka si bronchitis "teopeka" na a kwa ụbọchị dose nke na-erughị 900 mg theophylline content akara dịghị mkpa na onye ọrịa ahụ ọbara. Ọ bụrụ na ị na-elele mpụta ìhè nke igbu egbu, mkpa dị ngwa ka akara n'elu larịị nke ịta nke isi n'ọrụ mgwa ke iyịp. Best atụle egosi 10-20 micrograms kwa ml. Ọ bụrụ na ndị theophylline ọdịnaya nke ọrịa ọbara dị elu karịa nkịtị, ndị hụrụ mmepe nke iwe. Na nke a ọ dị mkpa iji belata na onunu ogwu nke ọgwụ, na a ọgwụgwọ mmetụta ga-mbà.

Ga na-ịṅụfe ọgwụ ike ókè?

Bronchodilators dị ka "teopeka" nwere ike ime ka oké njọ ọrịa nke ahụ ahụ na ihe omume nke ovadozu. Mgbe kwesịrị ekwesị adịkwa kwa ụbọchị ọnụego nke na-anata n'aka ndị na-esonụ mgbaàmà nwere ike ibili:

• ebelata agụụ;
• ehighị ụra nke ọma;
• afọ ọsịsa;
• ventricular arrhythmias udi;
• tachycardia;
• agba ọbara nke digestive usoro;
• tachypnea;
• tremor;
• nchegbu;
• flushing nke anụ ;
• ụba excitability;
• egwu ìhè;
• na-agbọ ọbara.

Ọ nwekwara ike ịzụlite oké nsi, nke na-egosipụta onwe ya na ndị na-esonụ mgbaàmà:

• omume nke akwụkwụ ọdịdọ;
• hypokalemia;
• gbasara akụrụ odida, myoglobinuria;
• hypotension;
• mgbagwoju anya;
• hyperglycemia;
• metabolic acidosis.

Gịnị na-eme na nke a?

Ọ bụrụ na e nwere ihe gosiri nke ihe ịrịba ama ma ọ bụ enyo nke ha mkpa ka a gastric lavage, nye onye ọrịa chelators, laxatives, ọgwụ ọjọọ, dị ka nke ọma dị ka ịhazi diuresis plasmasorption, hemodialysis na hemosorption. Ọ bụrụ na onye ọrịa na-enwe ihe ọdịdọ ahụ, ọ na-atụ aro ka ịme oxygen ọgwụ na igba ogwu n'akwara "Diazepam" nke ga-enyere n'ụzọ dị irè-ijide ọdịdọ. N'ihe banyere akpọ ọgbụgbọ na vomiting ga-ahọpụta igba ogwu n'akwara "Ondansetron" ọgwụ ọjọọ na "Metaklopromida".

Gịnị ọgwụ ike ga-achọkwa "teopeka"?

Bronchodilators dị ka "teopeka 'ikpenyeneke ọnụ na a macrolide-ọgwụ nje" Allopurinol "," cimetidine "," Lincomycin "," isoprenaline ", nakwa dị ka ọnụ na gbochie afọ n'ihi na ndị a ọgwụ ọjọọ aka belata nwechapụ nke theophylline.

Ọ na-adịghị na-atụ aro na ikpokọta oriri nke beta-blockers, karịsịa ndị na-abụghị nhọrọ, na ọgwụ ọjọọ, "teopeka", nke nwere ike ịzụlite bronchial constriction na ọnụ bronchodilator mmetụta nke theophylline.

Ọ bụrụ na "teopeka" etinyere ọnụ na "Furosemide" caffeine na ndị ọzọ na bekee na-akpali beta-2 adrenergic anabata, ọrụ nke ya bụ isi akụrụngwa na-budata ụba. Ọ bụrụ na jikọtara na theophylline "Aminoglutitemidom", akpa ihe onwunwe na-amalite ifịk ifịk anyụpụ si ahụ na ya arụmọrụ tụlee.

"Acyclovir" bụ ike dịkwuo ịta nke isi n'ọrụ mgwa "teopeka" na-enwekwu ndị na-ezighị ezi mmetụta nke ya n'ikuku. Yiri phenomena na-hụrụ mgbe co-ndinọ na theophylline ọgwụ ọjọọ "Dialteazem", "Felodipine" "Verapamil", "Nefedipin". A ọgwụ na-adịghị agbanwe bronchodilator mmetụta, Otú ọ dị, onye ọrịa nwere ike mgbaàmà nke oghom Jeremaya mere ma ọ bụ ovadozu.

Umi "Disulfiram" ike nke na-amụba theophylline ọbara oké egwu na-egosi ihe ize ndụ na-egbu egbu lesion. "Propranolol", na iche, na-ebelata "teopeka" nwechapụ nke nọ n'ọrụ umi. Ịta nke theophylline na-amụba site somestnom ya n'ikuku na "enoxacin" na fluoroquinolones. Mgbe theophylline ọgwụ mbelata arụmọrụ nke lithium salts.

Ọ bụrụ na jikọtara ọgwụgwọ na "pentobarbital", "Carbamazepine", "Isoniazid", "rifamycins", "sulfinpyrazone" ụba nwechapụ "teopeka" na-ebelata ya irè. Mgbe concomitantly na theophylline "phenytoin" e ibe mgbochi nke nọ n'ọrụ akụrụngwa na onye ọrịa ahụ ọbara.

Ụkpụrụ nduzi ndị a bụ mkpa karịsịa, na-eleghara ha bụ fraught na nsogbu ahụ ike. Ya mere, tupu ewere "teopeka", na-agụ ntụziaka ọma. Na ọ bụrụ na ị na-na-emeso n'ihi na ihe ọ bụla nke dị n'elu ọgwụ, ịkpọ gị dọkịta.

Olee otú ịzụta ọgwụ na otú ọgwụ bụ uru?

Na echiche nke ndị dị oké njọ contraindications na mmetụta nke a ọgwụ, "teopeka" wepụtara na pharmacies naanị site ọgwụ.

Drug "teopeka" price bụ nkezi na Russia bụ 160 rubles, adade ke pharmacies site iche iche na-emepụta. Otu ụdị - ọgwụgwọ maka "Borschagovsky CPP SPC" Ukrainian ọgwụ na ụlọ ọrụ. Ya na-eri bụ 155 rubles. Russian mmepụta nke "teopeka" ọgwụ ọjọọ, 300 mg a rụrụ na ụlọ ọrụ nke JSC "Pharmaceutical azụmahịa" na "Valens". ọgwụ ndị a na-eri 290 rubles na 190 rubles karị.

Ke ofụri ofụri, ọgwụ ọjọọ, "teopeka", na price na-anara, na-ewere ọnụ na nkà mmụta ọgwụ na ọtụtụ ndị anyị na ụmụ amaala. Tụnyere European ogbo ngwá ọrụ a dị ukwuu dị ọnụ ala karịa. Russian mmepụta nke "teopeka" ọgwụ mere ka ọ oké ọnụ.

Adọ aka ná ntị mgbe na-ewere ọgwụ

Mgbe inweta "teopeka" ọgwụ ọjọọ, reviews nke ọma, na-elekọta ndị na-esonụ ozi. Ọ bụrụ na onye ọrịa nwere akwara ma ọ bụ gbasara obi insufficiency, atherosclerosis, cardiomyopathy, eriri afọ ọnyá afọ, ọrịa imeju, prostate cancer, oesophageal reflux, afọ ime, hypothyroidism ma ọ bụ na ụba propensity ka ihe ọdịdọ, ọgwụ theophylline kwesịrị iwere na ịkpachara anya.

Children n'okpuru afọ 12 na ndị okenye ọrịa "teopeka" họpụtara adịkarịghị.

Ikekwe iji rectal forms nke ọgwụ, ma ha ga-eji anya akpachapuru anya nke na pathologies nke ikensi na afọ ọsịsa syndrome. Ọrịa na riri ahụ na-ese anwụrụ mgbe ẹsụhọde mmetụta nke ọgwụgwọ "teopeka".

Weere inadmissible nkwonkwo ọgwụgwọ theophylline na xanthine emepụta. Ọ bụrụ na onye ọrịa na-agadi kwuo concomitant ọrịa, malitere ịrịa ọrịa, ọrịa imeju, obi na ọbara arịa, dọkịta dị mkpa iji gbazie dose nke nkà mmụta ọgwụ.

M ga a ọgwụ ka ụmụ nwaanyị dị ime?

A nwaanyị dị ime na-agwọ ọrịa na-egosi na n'ihi na ọnụnọ nke oké na-egosi ebe theophylline bụ ike banye n'ime Plasenta. Ọ bụrụ na n'ikuku "teopeka" na-egosi ara na nne, lactation ga-kwụsịrị.

Nke a ntuziaka bụ a mfe version nke zuru ezu na ntụziaka, nke a na-mmasị ka ọgwụ ọjọọ, "teopeka". Ọ ga-agụ nke ọma n'ihu na-eji ya. Ọ bụrụ na e nwere ihe ị na-mgbagwoju anya ma ọ bụ abụọ, ịkpọ gị dọkịta.