Analogs na ntuziaka maka ojiji "lomefloxacin"

Gịnị nwere ike dochie ndị dị otú ahụ a ọgwụ dị ka "lomefloxacin"? Analogs nke ọgwụ, nzube ya, na ihe mgbochi na ojiji nke ọgwụgwọ Njirimara na-atụle n'isiokwu n'okpuru. Ị ga-amụtakwa banyere otú kwesịrị ekwesị iji ngwá ọrụ a, na ihe onunu ogwu.

Ụdị nke ọgwụ, ya nkwakọ, na ya akụrụngwa akụkụ

Nke ngwugwu dị nke ego? Ebe ọ na-enye ntụziaka na ngwa? "Lomefloxacin" - a mbadamba, enịm ke blisters na packaged ke akwụkwọ Ukwu, ọnụ na nchịkọta.

Gịnị bụ ndị Efrata na-agụnye ọgwụ? The n'ọrụ mgwa nke ọgwụ bụ lomefloxacin hydrochloride. Ọzọkwa ọ na-agụnye ndị ọzọ inyeaka mmiri.

The ọgwụgwọ Njirimara nke ọgwụ

Gịnị bụ mkpụrụ ọgwụ "lomefloxacin"? Manual na-ekwu na nke a bactericidal antimicrobial ọgwụ ahụ bụ nke a otu antibiotikopodobnyh ego, ya bụ, fluoroquinolones, na-anọchite anya nke abụọ ọgbọ nke ndị a ọgwụ ọjọọ.

Gịnị na-akpata na antimicrobial nrụpụta nke ọgwụ na-atụle? Dị otú ahụ Njirimara "lomefloxacin" Mbadamba (400 mg) e nwetara ekele eziokwu na ha nọ n'ọrụ umi bụ ike nke na a igbochi utịp ke DNA gyrase (i.e. nje enzyme) nke na-enye supercoiling. Ọzọkwa, a gị n'ụlọnga na-emepụta a ufọk ufene compound (mgbagwoju) na ya tetramer na disrupts DNA transcription na replication nke nje na mkpụrụ ndụ, na-eme ha ụdi mbibi.

The kwuru na ọrụ nke agwọ ọrịa na-egosi dịtụ ọjọọ aerobic bacteria dị ka gonococci, Salmonella, pseudomonas, Haemophilus na Escherichia coli, ọrịa ọgbụgbọ na ọnyụnyụ pathogen, meningococci, Shigella, Morganella na na. Ọzọkwa agwọ ọrịa "lomefloxacin" (400 mg) mwute mmetụta a Proteus, chlamydia, Campylobacter, mycoplasma, legionella, ụfọdụ pneumococci na staphylococci.

Anyị apụghị ikwu na kwuru ọgwụ bụ ukwuu irè megide Mycobacterium ụkwara nta. Ọ bụ ike belata usoro iheomume nke ha mwepụ, nakwa dị ka n'oge resorption nke dị infiltrates.

Therapeutic mmetụta "lomefloxacin" ka ọbụna ke ala kasịnụ na ọbara. Ọ bụrụ na a na-eguzogide na- hụrụ nnọọ adịkarịghị.

Kinetic ike ọgwụ mbadamba

Olee otú etinye obi gị dum, sị agwọ ọrịa? Ihe o kwuru ntuziaka maka ojiji? "Lomefloxacin" nwere ezi absorbency. Mgbe na-anata ọgwụ ya elu plasma ịta enweta n'ime 55-85 nkeji.

The plasma protein ejikọ ọgwụ naanị na 10%. Ọzọkwa, ọ na-ezi absorption Njirimara dị iche iche akụkụ na anụ ahụ (gụnyere kenwe, njikọ, akụkụ okuku ume na ụzọ, ENT akụkụ, pelvic akụkụ, ọkpụkpụ, afo, adụ anụ ahụ, wdg), ebe ya ọdịnaya bụ 5-7 ugboro elu plasma.

Ọ ga-kwuru na ụfọdụ n'ime lomefloxacin metabolized na Nleta ọtụtụ emepụta.

Oge nke excretion nke ọgwụ bụ 9 awa. Mmepụta ya site na tubular secretion na mmamịrị (70-85%) na na nsị (25-30%).

Egosi maka designation nke n'aka

Mmadụ ole na ole maara na, ma na-ere ọgwụ ígwè pụrụ ịchọta bụghị naanị Erere "lomefloxacin", ma na-ọgwụ ọjọọ, "lomefloksatsin + pyrazinamide + ethambutol + Prothionamide + Pyridoxine". Na nke a ma nke si agwọ ọrịa na-egosi maka ojiji na:

• na-efe efe (purulent) akpụkpọ adụ anụ ahụ (gụnyere Burns, nje ọnyá, wdg);
• osteomyelitis;
• chlamydia na gonorrhea (gụnyere Blepharoconjunctivitis na chlamydial conjunctivitis);
• Eriri afọ tract na-efe efe (e.g., ọrịa ọgbụgbọ na ọnyụnyụ, ọnyụnyụ ọbara, ọrịa ịba ahụ ọkụ, salmonellosis);
• Akụkụ okuku ume na-efe efe (gụnyere-adịghị ala ala bronchitis, ntighari ụdị);
• biliary tract-efe efe;
• efe efe na urogenital ebe (e.g., urethritis, prostatitis, cystitis, pyelonephritis);
• akpa ume ụkwara nta (gụnyere na ọgwụgwọ nke ndị na-ngwa ngwa na-enwe ọganihu forms nke ọrịa, nakwa dị ka ụba iguzogide "isoniazid" na "Rifampicin" na iguzogide ọgwụ);
• tupu mgbe transurethral ịwa ahụ (naanị maka prophylactic nzube).

Bans nhọpụta nke antimicrobial mbadamba

Mgbe ụfọdụ, i nwere ike iji ọgwụ ọjọọ na-atụle? Gịnị a na-agwa ntụziaka ntuziaka? "Lomefloxacin" na-contraindicated maka ojiji na:

• gestation;
• ara;
• onye uche nke ọgwụ ọjọọ nke na fluoroquinolone otu;
• ka umuaka (ikekwe mgbochi nke skeletal development).

Ntuziaka maka ojiji

"Lomefloxacin" - ọgwụ na-na na-egosi na ingestion. Ha kwesịrị iwere otu ugboro n'ụbọchị, n'agbanyeghị nke nri, na-aṅụ ihe 230 ml nke nkịtị mmiri.

Na oge nke ọgwụgwọ na a na nkà mmụta ọgwụ na-adabere na nchoputa, nakwa dị ka ogo nke ọrịa na uche nke nje ahụ.

-Adịghị mgbagwoju nnukwu bronchitis na bronchopneumonia eruba emeso onunu ogwu nke 400 mg nke ọgwụ n'elu ụbọchị iri.

Na ọgwụgwọ nke chlamydia (urogenital), gụnyere nje na chlamydial, gonococcal na chlamydial-efe efe, ọrịa ndinọ 400-600 mg nke ọgwụ kwa ụbọchị, na oge nke ngwa 28 ụbọchị.

Ọgwụgwọ nke nlọghachi mgbagwoju anya oyi baa na-adịghị ala ala bronchitis ụdị rụrụ na a kwa ụbọchị onunu ogwu hà 400-800 mg nke ọgwụ, maka izu abụọ.

Mgbe mycoplasma ọrịa na-ewere ọgwụ ọjọọ na kenyere ka 400-800 mg kwa ụbọchị, na oge nke ochichi nke mbadamba nkume ndị 3 izu.

Urinary tract-efe efe ọrịa amenable ọgwụ 400 mg nke ọgwụ. Na nke a na ọgwụgwọ nke na-adịghị mgbagwoju ikpe rụrụ maka 5 ụbọchị, na mgbagwoju anya - 14 ụbọchị.

Na gonorrhea nnukwu ọgwụ "lomefloxacin" na-atụ aro na-a onunu ogwu nke 600 mg. Ma ihe ndị na-adịghị ala ụdị ọrịa ahụ, ya ọgwụgwọ a rụrụ ke ukem kpọmkwem immunotherapy. Na nke a, na-ọgwụ na otu kwa ụbọchị dose maka 5 ụbọchị.

Ọgwụgwọ nke akpa ume ụkwara nta nwere ike buru 14-30 ụbọchị (na ụfọdụ ruo ọnwa 3). Ndị dị otú ahụ na ọrịa na-emeso ọgwụ dose nke 200 mg ugboro abụọ n'ụbọchị.

Mgbe kwuru gbasara akụrụ pathologies ma ọ bụ agafeghị oke uwa, nakwa dị ka ndị mmadụ n'ịnwụ hemodialysis, "lomefloxacin" na-ndinọ ke ichekwa 400 mg kwa ụbọchị, na ya n'ihu ọnụ 200 mg.

Onu nke a na-adịghị mma agwa

Gịnị mmetụta ọjọọ nwere ike ime ka mkpụrụ ọgwụ "lomefloxacin"? Eduzi ihe ndị na-esonụ omume:

• bronchoconstriction, mụbara imi secretion, ọgbụgbọ, ụkwara, dysphagia;
• dyspnea, vomiting, akụkụ okuku ume na-efe efe, afọ ọsịsa, goiter;
• flu-dị ka ihe mgbaàmà, dysgeusia, epigastric mgbu, bloating;
• elu nke imeju enzymes, nkụ ọnụ, eriri afọ ọbara ọgbụgba;
• ntachi, arthralgia, nwa ehi cramps,-agbanwe asụsụ nke agba, myalgia;
• pseudomembranous afọ, isi ọwụwa, mgbanwe agụụ, vasculitis, dizziness;
• ehighi ura, ara nro na azụ, ike ọgwụgwụ, ahụ ịma jijiji, a n'echiche nke general malaise, ịda mbà n'obi, ala ịma jijiji;
• hyperkinesia, ike ọgwụgwụ, ụfụ, ịmụ anya arọ nrọ;
• mgbu na anya, mkpọtụ, na ihe mgbu na nti;
• dysuria, mụbara agụụ, hematuria, paresthesias;
• crystalluria, bịara ikiri ọhụụ;
• albuminuria, glomerulonephritis, Leucorrhœa, edema, polyuria, epididymitis, ike nwoke, orchitis, tenesmus;
• cyanosis, anuria, hypotension, vaginitis, tachycardia, arrythmia, perineal mgbu, bradycardia;
• intermenstrual agba ọbara, thrombocytopenia, mmamiri candidiasis, myocardial infarction, cardiomyopathy, phlebitis;
• na progression obi odida na rịaworo, purpura, cerebrovascular ọrịa, itching nke anụ;
• akpa ume embolism, photosensitivity, dịkwuo fibrinolysis, ọkụ ọkụ, lymphadenopathy, ọkụ ọkụ;
• epistaxis, erythema (ịza aza), na-eche akpata oyi, gout, na-ekpo ọkụ mgbukepụ;
• superinfection, hypoglycemia, candida, na adịghị emetụ ha n'ahụ nke akpịrị ịkpọ nkụ.

An ovadozu ọgwụ

Na ihe ovadozu nke mkpụrụ ọgwụ "lomefloxacin" ọrịa na-enwe ọgbụgbọ, erosive ọnya nke eriri afọ mucosa, amụba nke QT-oge, dizziness, ọdụdọ, mgbagwoju anya, nakwa dị ka ụba oghom Jeremaya mere.

N'ihi hemodialysis ovadozu pụtara atụle adighi ike ọgwụ n'elu ọnọdụ a rụrụ na ndabere nke ẹdude mgbaàmà.

Mmekọrịta ndị ọzọ ọgwụ ọjọọ eme ihe

Na Nchikota "lomefloxacin" na "theophylline" ya metabolism fọrọ nke nta eru.

Mgbe imekotaotuugbo ochichi nke antacids na sucralfate ii chelate okụre na belata bioavailability nke lomefloxacin. Ọ bụ ya mere n'agbata n'ikuku nke kwuru ka ọgwụgwọ kwesịrị dịkarịa ala 4 awa.

Joint iji "lomefloxacin" na elu doses nke caffeine prolongs ọkara ndụ nke ikpeazụ.

Na ọgwụgwọ nke ụkwara nta na-ekwesịghị ekenịmde ke ukem na n'ikuku nke ego "Rifampicin", ma ọ ga-eduga adomokoro edinam.

Imekotaotuugbo ọgwụgwọ na NSAIDs enwekwu toxicity nke ọgwụ ọjọọ na nwere ike ime ka ihe ọdịdọ.

"Lomefloxacin" ike dịkwuo arụmọrụ nke anticoagulants maka onu ochichi.

Ọgwụ, nke na-blockers nke tubular secretion, inhibit excretion nke "lomefloxacin".

kpọmkwem na-atụ aro

Ọ bụrụ na gbasara akụrụ ọrịa na-achọ a amanyere bụ iwu ukpụhọde nke dose, nke na-adabere na QC metrics.

All na ọgwụ dị mkpa ka ị na-ezere ogologo mmetụta nke ọ bụla UV ìhè, gụnyere ìhè anyanwụ.

Vitamin mmadụ na-agụnye dị iche iche ịnweta nwekwara ga-120 nkeji mgbe ma ọ bụ tupu ewere anata mkpụrụ ọgwụ.

yiri ọgwụ ọjọọ

Agwọ ọrịa "lomefloxacin" nwere ọtụtụ analogues. Isi dochie ọgwụ ọkachamara tụlee: "Abaktal", "Elefloks", "Zanotsin", "TSifran", "Avelox", "Tsiprolet", "Zofloks", "tsiprinol", "Kvintor" "Ciprofloxacin", "Levofloxacin "" tarivid "," Levotek "," pefloksatsina "," Levofloks "," Ofloxacin "," Norbaktin "," Ofloks "," norfloxacin ".

Mbadamba "lomefloxacin": reviews

Mgbe o doro anya na kwuru na ọ bụ na-efe efe gị n'ụlọnga na-emetụ nke abụọ ọgbọ nke fluoroquinolones, nakwa dị ka ndị ziri ezi nhọrọ nke ọgwụ doses na ruo ogologo oge ọgwụgwọ, reviews banyere ugbu ụzọ kpere mma.

Dị ka okwu nke ọrịa, nke a ọgwụ ọjọọ abụrụwo onwe ya dị ka onye dị irè antimicrobial ọgwụ na ọma na-emekọ dị iche iche na-enweghị nchịkwa na microorganisms. Otú ọ dị, ụfọdụ ndị ọrụ na-ekwu na a ọgwụ mgbe ụfọdụ na-akpata mmepe nke ụfọdụ mmetụta, ma dị ka a na-achị, ha na-arịa ọrịa-kọwaa ọdịdị ma ọ bụ ndị onwe ha ozugbo mgbe ọgwụgwụ nke usoro ọgwụgwọ.