"Diferelin": reviews, analogs, na ntuziaka maka ojiji

Otu n'ime ihe ndị kasị dị irè ọgwụ e mere mbuso oké daa ọrịa nke nwanyi na nwoke omumu usoro, bụ ọgwụ "Diferelin". Ntụziaka, na price nke a ọgwụ a na-atụle site ọrịa na pụrụ iche forums. Dị na mbụ, na a ọgwụ nwere ya na-akwado ma na-emegide. Ke ibuotikọ emi anyị ga-atụle usoro nke ihe nke a ọgwụ na ya pharmacological e ji mara.

Therapeutic

Nkwadebe "Diferelin" bụ ọgwụ na antigonadotropnym edinam. N'eziokwu, ọ bụ ihe mgbochi-homonụ, dị ka ọ nwere ike na-ebelata mmepụta nke luteinizing hormone na follicle-akpali akpali hormone na nwanyi na testosterone na mmadụ. Ya mere, "Diferelin" ọgwụ ifịk ojiji maka ọgwụgwọ nke eriri akpa nwa fibroids, endometriosis, prostate cancer, n'oge mmalite oge uto na-eto eto na ọrịa ndị ọzọ.

Structure na mejupụtara

Nkwadebe "Difelerin" bụ ugbu a dị naanị na a otu onunu ogwu ụdị - lyophilisate ike ngwọta. N'otu oge ahụ, ọ na-eme atọ di iche iche nke ngwaọrụ, dị iche iche kasịnụ nke nọ n'ọrụ umi na-enwe a dị iche iche na nzube:

• "Diferelin" 11,25 mg na 3,75 mg - intramuscular injection;
• "Diferelin" 0,1 mg - maka subcutaneous ogwu ogbugba.

Na ojiji, dọkịta na ndị ọrịa n'oge na-adịghị kwuru na dị ka e hotara na mbụ iche nke ọgwụ, na-agbakwụnye ya aha na ọnụ ọgụgụ na-akọwa ọdịnaya nke isi umi.

Dị ka ihe na-arụsi ọrụ ike mgwa ọgwụ "Diferelin" Fim nke predominantly mma eme triptorelin pamoate. Na ya na-akpa na-enwe ndidi akpọ ọgwụgwọ na pharmacological mmetụta.

Agwọ ọrịa "Diferelin" ere katọn, nke e nwere na karama lyophilisate na ntụtụ agịga abụọ. Ọzọkwa, ha na-etinye vials nke mgbaze. Ọ nwere ike ịdị iche iche. Ọ bụrụ na lyophilizers "Diferelin" 3,75 na 11,25 mannitol na-eji ọkacha mma, na agwọ ọrịa na a ịta nke 0,1 mg a na-eji ọtụtụ saline.

Therapeutic mmetụta "Diferelin"

Site a Biochemical ele ihe anya n'ọrụ hormone ọgwụ bụ ihe analọg nke GnRH synthesized hypothalamus. Ọ na-emetụta ndị pituitary gland bụ maka mmepụta nke mmekọahụ homonụ, si otú inye iwu na-arụ ọrụ nke nwanyi na nwoke omumu usoro: na prostate gland, ovary, akpanwa, testicles. Ọ na-enyo na-achịkwakwa mmepụta nke mmekọahụ homonụ na nkà mmụta ọgwụ "Diferelin".

Nyocha nke ya ngwa na-atụ aro na ọ nwere ike mgbochi-akpụ na antigonadotropnym edinam na ọ dị irè na ọgwụgwọ nke ụfọdụ pathologies. Ka ihe atụ, infertility, a na nkà mmụta ọgwụ suppresses mmepụta nke luteinizing hormone, nke na-ezighị ezi na-emetụta ovulation, si otú amụba ohere nke ime. A prostate cancer agwọ ọrịa, nke a na-ebelata testosterone na ọkwa-efu, nke bụ ihe e ji mara maka castrates, na-enwekwu ndị ọrịa Ohere nke ịlụ Bibie cancer.

Irè anwansi "Diferelin" na endometriosis. Ha mmetụta na mmepụta nke mmekọahụ homonụ nwayọọ nwayọọ na-abanye a nwaanyị na keakamere steeti menopause na otú akpalite atrophy endometriodnyh foci.

egosi

Dabere na kasịnụ nwere dị iche iche mmetụta na organism ọgwụ "Diferelin". The ojiji nke a ọgwụ na nkà mmụta ọgwụ na-adabere na ọdịnaya Isi nọ n'ọrụ mgwa. Ka ihe atụ, injection "0,1 mg Diferelin" gosiri na infertility, maka revitalization nke ovarian mmalite na ovulation na IVF.

The ojiji nke a ọgwụ na a ịta nke 3,75 mg amamihe mgbe emeso prostate cancer, fibroid akpanwa, akaghi chaa, Genital na extragenital endometriosis, IVF ogbugba ndu.

Na kasị njọ ikpe nke prostate cancer na metastases na-adịghị ala ala endometriosis, họpụtara n'ikuku "Diferelin 11,25 mg." Ya iji ike budata melite ọrịa Ohere nke mgbake.

Ntuziaka maka ojiji

Medicine "Diferelin 0,1 mg" na-eji na obere na ogologo IVF ogbugba ndu n'okpuru ike ike na-elekọta. Ọ na-ndinọ kwa onye ampoule si ụbọchị nke abụọ nke oge ịhụ nsọ nwaanyị. Na oge nke a ọgwụgwọ na-ekpebisi ike site na onye e ji mara nwaanyị ahụ.

Ma ọgwụ ọjọọ, "Diferelin 11,25 mg" ndinọ ọrịa ọ bụla ọnwa atọ. Na ndị ikom nwere ike ime ka na-agbanye n'oge ọ bụla, na ndinyom - na na mbụ ụbọchị ise nke ịhụ nsọ okirikiri. Na oge nke ọgwụgwọ na a ọgwụ ekwupụtakwa na atọ ka ọnwa isii, dị ka ihe karịrị ọnwa isii, ọ na-adịghị atụ aro.

The widest nso nke ngwa na nkà mmụta ọgwụ "Diferelin 3,75". Nleba egosi na irè nke a ọgwụ. Ọzọkwa, ọ bụ nnọọ adaba iji, ebe ọ na-adịghị achọ kwa ụbọchị ochichi maka a ogologo oge. Ọgwụ "Diferelin 3,75 mg" nke ọgwụ na-na-emekarị mere otu ugboro a ọnwa. Nke a bụ zuru ezu iji hụ na nnyefe nke-arụ ọrụ bekee n'ime n'ọbara na ọgwụgwọ Dosages. Ka anyị tụlee ngwa nke a circuit agwọ ọrịa maka ọrịa dị iche iche.

prostate cancer

Men na-adịghị gosiri maka prostate cancer ọgwụgwọ "Diferelin". Ọgwụ nke onye ọrịa na-enịm ọ bụla iri abụọ na asatọ ụbọchị, nke mere na n'agbata ochichi nke ọgwụ bụ izu anọ. A otu dose of agwọ ọrịa ngwa - otu mkpọ 3,75 mg. Na oge nke ọgwụ ochichi na-ekpebisi ike site na ọnụego nke na-agwọ ọrịa nke onye ọrịa.

endometriosis

Ọgwụ nke ọgwụ "Diferelin" ndị inyom na endometriosis dị na mbụ ụbọchị ise ọzọ nsọ ya. A ụdi dose ọgwụ na-emepụta izu anọ, na ọgwụgwọ N'ezie dịruru a ngụkọta nke 3 ruo 6 ọnwa. Ọ ga-eti na a ọgwụ ike ga-achọkwa na ojiji nke ọnụ na gbochie afọ.

Na ọgwụgwọ nke endometriosis akpata wuru menopause (amenorrhea) nkwadebe "Diferelin". Nyocha nke ọrịa, Otú ọ dị, na-egosi na mgbe cessation ọgwụgwọ ịhụ nsọ okirikiri a weghachiri eweghachi n'ime ọnwa ole na ole, mgbe ụfọdụ, a afọ. Ugboro ugboro ọgwụgwọ na a na nkà mmụta ọgwụ na ntighari endometriosis, dị ka a na-achị, na-adịghị kenyere - n'ihi nzube a, ndị ọzọ, na-erughị irè ọgwụ.

Adrenarche

Children na-ejide akaghi pubati ọgwụ "Diferelin" ndinọ ozugbo ọ bụla 28 ụbọchị. N'ihi ya otu dose nke ngwa gbakọọ si arọ nke onye ọrịa. The ụmụaka na a arọ n'elu 20 kilogram ẹkenam a vial (3.75 mg), na ụmụaka na-nta indices - ọkara ampoule (1.875 mg). Na oge nke ọgwụ kpebisiri ike site ịga dibịa dabere na ọsọ nke normalisation nke ọrịa na-arịa.

eriri akpa nwa fibroids

Na ọgwụgwọ nke ọrịa a na-ndinọ ozugbo a ọnwa maka otu na nkà mmụta ọgwụ na karama "Diferelin". Na ya n'ikuku ga-rụrụ n'oge mbụ ụbọchị ise nke ịhụ nsọ okirikiri nke onye ọrịa. Ụdi injections nke ọgwụ ime anọ ọ bụla izu. Duration nke ọgwụ bụ a na-erughị ọnwa atọ.

ovadozu

Ugbu mata ihe ọ bụla ikpe nke ọgwụ "Diferelin" ovadozu. Nleba egosi ya ikwu nchekwa. Ke adianade do, ọgwụ nwere dịghị utịp ke ịta na ikike ịchịkwa na-akpali akpali usoro. Ya mere, n'oge ọ na nke ọgwụ na a ọgwụ na ọ bụ nchebe ụgbọala.

mmetụta

Mgbe iji "Diferelin" ọgwụ nwere ike ndị na-esonụ mmetụta:

• mgbaàmà nke ọgidigi azụ mkpakọ;
• ihe mgbu ka ukwuu;
• Angioedema, urticaria, itching;
• ureteral mgbochi;
• isi ọwụwa;
• ọkpụkpụ demineralization;
• ebelata potency;
• mmamiri nkụ;
• ọsụsọ na-agba;
• Mbelata testes;
• mgbanwe ara size;
• hypogonadotropic amenorrhea;
• hypertrophy nke ovaries;
• menorrhagia;
• asthenia;
• ọgbụgbọ, vomiting;
• ọbara mgbali;
• na-ekpo ọkụ mgbukepụ;
• bịara ikiri ọhụụ ;
• obi lability;
• hematuria;
• ntoputa nke ngafe arọ;
• elu edema;
• fever;
• anorexia;
• ịda mbà n'obi;
• tachycardia;
• alopecia;
• dyspnea;
• nācha ọbara-ọbara na ọgwụ saịtị;
• paresthesia.

contraindications

Na ọgwụ "Diferelin" E nwere ụfọdụ contraindications maka ojiji. Ha na-metụtara ọrịa na-ala nke ahụ ike, nakwa dị ka onye n'ahụ mara. Dị ka ihe atụ, ndị ikom na-apụghị iri a ọgwụ na hormone-onwe ha prostate cancer na mgbe mwepụ nke testicles, na ndị inyom na-adịghị atụ aro n'oge ime, ara, na polycystic ovary syndrome. Onye ọ bụla, na-enweghị isịneke, mkpa na-eji ọgwụ na-elezi anya "Diferelin" osteoporosis na hypersensitivity ka ya mmiri. Ọ bụrụ na ọ bụla oghom mgbaàmà, onye ọrịa kwesịrị ozugbo ịkpọ onye dọkịta.

General ala mgbe ngwa

Dị ka e kwuru n'elu, na ọgwụ ọjọọ, "Diferelin" egbochi mmepụta nke mmekọahụ homonụ na ndị ikom na ndị inyom, si otú na-ewebata ha n'ime a kwuo nke wuru castration. O doro anya na nmikpu na ndị dị otú a kwuo na mmepụta ya na-esonyere site iche iche na psychological, endocrine-metabolic na neuro-vegetative ọrịa.

Mgbe mmezu nke ọgwụ na a ọgwụ homonụ weghachiri eweghachi, ma n'oge a na usoro nwere ike ịdị mgbagwoju anya n'ihi ọrịa ogwe, ike ọgwụgwụ, isi ọwụwa, sweating, na-ekpo ọkụ mgbukepụ, ịda mbà n'obi, ahụ ọkụ na ndị ọzọ wetara ihe mgbaàmà. Otú ọ dị, otu onye na ọkara ọnwa mgbe ọgwụgwụ nke ọgwụ ndị ọrịa ọnọdụ bụ kpamkpam nkịtị. Nke ahụ bụ, n'ozuzu mgbe ikpeazụ injection "Diferelin 11,25 mg" hormone itule na-weghachiri eweghachi mgbe 4.5 ọnwa, na ihe nke ọgwụ na a ịta nke 3,75 mg risịrị mgbe 2.5 ọnwa. N'oge ndị a oge na ndị inyom na ndị ikom n'ụzọ zuru ezu gbanwee omumu na mmekọahụ ọrụ na libido afiakde nkịtị.

Pregnancy

Mgbe nwa-amị ọgwụgwọ "Diferelin" contraindicated. Otú ọ dị, nke a na nkà mmụta ọgwụ na ọtụtụ-eji aka ovulation. Ọtụtụ ndị inyom na-enwe ike na-atụrụ ime mgbe ọtụtụ injections nke ọgwụ, ma na-enweghị ebe ọ maara na ya, anọgidewo na-na-na nkà mmụta ọgwụ "Diferelin". Mmetụta nke a ọgwụ bụ ike iru, adịghị emerụ ahụ nwa e bu n'afọ: bụghị akpasu ihe ize ndụ nke ime ọpụpụ na a anaghị eme ka mmepe nke congenital malformations. Otú ọ dị, usoro nke ihe nke ọgwụ ọjọọ na nwanyi omumu usoro n'oge ime ka na-achọ ịkpachara anya na-amụ.

Drug analogues "Diferelin"

Na nke ugbu a na-emepụta ọgwụ ahịa e nwere nanị otu ọgwụ ọjọọ na-agakọta, ebe ya mejupụtara bụ otu ihe ahụ nọ n'ọrụ mgwa - bụ "Dekapeptil". Ke adianade do, pharmacies pụrụ ịchọta ọgwụ ọjọọ ndị nwere otu ọgwụgwọ mmetụta dị ka ọgwụ "Diferelin". A mmetụta yiri na ozu na-nyere site: ịgba "Buserelin" lyophilisate "Buserelin ebusa", "Zoladex" Capsule formulations "Eligardt" na "Lyukrin ebusa".

Nyocha

E nwere ma nke oma ma na-ezighị ezi nzaghachi na ojiji nke ọgwụ "Diferelin". Ọgwụ nke a ọgwụ dị iche iche mmetụta na ndị ọrịa. Ọtụtụ ndị inyom na ọbụna hụrụ a akara ọgwụgwọ mmetụta agwọ fibroids na ọrịa ndị ọzọ, Otú ọ dị, mkpesa nke mmetụta na-agụghị oké anabata ha na ọgwụgwọ: ibu ibu, na-ekpo ọkụ mgbukepụ, ogwe, ike ọgwụgwụ. N'otu oge, ihe niile ọrịa na-ekweta na a ule siri ike na-aṅụ ọgwụ ka mma oghere n'ịwa ahụ.

Na ọgwụgwọ nke prostate cancer na ndị ọzọ pathologies na ndị ikom na-erukwa mbuaha reviews na mmetụta nke ọgwụ ọjọọ "Diferelin". The price nke ọgwụ o yiri ka ọtụtụ na-anabata usoro nke ngwa nwekwara adịghị eju afọ, nakwa na ọ bụ irè ma ọ ekewet e ji otuto, n'ihi na ọ bụghị naanị na ewepu akpụ onwe ya, ma na-eliminates metastases na ọkpụkpụ. Otú ọ dị, e nwere adịghị mma reviews banyere ọgwụ "Diferelin" ruru ka isi ihe abụọ kpatara: ogbenye arụmọrụ ọgwụ ọjọọ na ụfọdụ kpọmkwem mgbe, na mmetụta ndị na-agụghị oké anabata ụfọdụ ọrịa na-eme ka ha kwụsị ịhọpụta ọgwụ ma ọ bụ kpam kpam dapụ nkịtị n'afọ iri na ụma nke ndụ.

ahịa

Gịnị bụ na-eri nke a ọgwụ ọjọọ, "Diferelin"? The price nke a na nkà mmụta ọgwụ dịgasị dabere dịgasị iche iche, ndị na-ere ọgwụ yinye, na nke ọ na-ere ere, na oke na ngwongwo. N'ihi ya, na nke ugbu a ahịa uru nke asaa vials "Diferelin 0,1 mg" àmà site 2597-3107 rubles. Kasị onunu ogwu ga-achọ ihe dị oké njọ investments: 1 karama "Diferelin 3,75 mg," onye na-azụ ga-akwụ site na 7632 ka 9076 rubles. Kwesịrị ịdị, ndị kasị oké ọnụ ọgwụ bụ a ukwuu ịta. Otu ampoule "Diferelin 11,25 mg" nwere ike zụrụ maka 18 269-23 100 rubles.

Kama elu bụ price nke ọgwụ "Diferelin". Yiri ngwaọrụ dị ọnụ ala, ma ha oru nwere ike obi naanị ahụmahụ dọkịta, n'ihi na ha nwere nnọọ iche pharmacological àgwà, contraindications na mmetụta.

ọgwụgwụ

Ugbu a na ị maara ihe niile banyere "Diferelin" Njirimara nke ọgwụ. Nke a mmiri ọgwụ ọgwụ irè megide ọtụtụ ọrịa, ma nwere ike ime ka a ọtụtụ mmetụta. Tupu mmalite nke ọgwụgwọ, ọ bụla ndidi ga-akwadebe maka eziokwu na ndị dị otú ahụ ọgwụ nwere ike ịbụ a siri ike ịma aka. Otú ọ dị, ọ bụla n'ihe ize ndụ bụ ziri ezi, ma ọ bụrụ na na eto bụ ahụ ike na mgbe ụfọdụ ndụ nke mmadụ. Ya mere adịghị enye ojiji nke ọgwụ ọjọọ, "Diferelin" ma ọ bụ dochie ya dị ọnụ ala karịa analogues. Ọ dị mma na-amalite usoro ọgwụgwọ na kasị irè n'aka na otú hụ na ọ bụ a mma pụta. Nọrọ mma!