Gịnị bụ neurosyphilis? Mgbaàmà, iche-iche, ọgwụgwọ, pụta

N'okpuru syphilis na-ezo aka Venereal ọrịa uwa, nke etịbede ụfọdụ esịtidem ngwa usoro. Na-anọghị nke eru ọgwụgwọ mgbe a obere oge, ọ pụrụ ịzụlite neurosyphilis, ji penetration nke ibute ọrịa n'ime ụbụrụ. Ọ bụ nnọọ ize ndụ ụmụ mmadụ ike daa ọrịa, egwu ngụkọta nkwarụ ma ọ bụ ọnwụ.

Gịnị bụ neurosyphilis?

N'okpuru neurosyphilis na-ezo aka ọrịa na-efe ọrịa nke Central ụjọ usoro nke mmadụ. Mmepe nke ọrịa a na-mere site penetration nke ahụ causative gị n'ụlọnga nke syphilis. The ọrịa nwere ike aka na-enweghị nchịkwa na usoro nke n'akụkụ nile nke ụjọ usoro si ụbụrụ na-agwụcha na uche ziri ezi. Clinically, ọrịa na-egosipụta site a ọnụ ọgụgụ nke akwara ozi ọrịa: dizziness, muscle adịghị ike, mkpọnwụ, ọdụdọ, mgbaka.

N'ihi na oge mbụ banyere syphilis ekwu okwu na Middle Ages. N'oge ahụ alchemists amaghị ihe neurosyphilis. Ahụhụ si na ọrịa, sonyere nke Crusades. N'oge Narị Afọ War syphilis ma ọ na-akpọ French ọrịa, dị ka British "ada" ya na Chile. Ọtụtụ iri afọ gara aga, syphilis e weere a ahiriokwu nke contagion. N'ihi ngwa mmepe nke sayensị taa, a na ọrịa nwere ike gwọrọ na a izu ole na ole. Otú ọ dị, elu forms na-abụkarị ndị na-akpata ọnwụ. Karịsịa mkpa maka elu enwe ọnụego nke neurosyphilis.

The ọrịa nwere ike isi gosipụta onwe gị na ihe ọ bụla oge nke syphilitic ọrịa. Diagnosis dabeere na ihe serological ụzọ nke nnyocha na-adakarị n'obiọma. Maka ọgwụgwọ nke ọtụtụ ndị na-eji ọgwụ nje na-warara-ụdịdị dị iche iche. Taa neurosyphilis ọrịa emee ọtụtụ obere ugboro ugboro karịa na narị afọ gara aga. Nke a bụ n'ihi na mma nke àgwà nke na-achọpụta ọrịa na usoro, mgbochi ule nke ndị bi na, n'oge ọgwụ.

The isi na-akpatara ndị ọrịa

Nje neurosyphilis - icha mmirimmiri treponema akpata. Ofufe Ọrịa emee kpọmkwem site onye ọrịa. A, nke a emee site unprotected mmekọahụ. Nje abatakwa ahụ mmadụ site ọnya na mucous membranes ma ọ bụ akpụkpọ. The ọrịa mgbe ahụ na-agbasa, tinyere n'ọbara.

The ahụ mkpatụ mba ọzọ bacteria site antibody mmepụta. Site na mbenata ọbara-ụbụrụ mgbochi icha mmirimmiri treponema ẹkenam n'ime ụjọ usoro. N'ihi ya nwayọọ nwayọọ na-emepe emepe neurosyphilis.

Na-akpata ọrịa a nwekwara ike na-eyi nonspecific. Development nke ọrịa na-egbu oge ọgwụgwọ na-akwalite na mbụ iche nke ọrịa, nsogbu mmetụta uche, belata ọgụ, isi unan, ike ọgwụgwụ.

Isi ụzọ nke ọrịa:

1. Mmekọahụ. Ọ bụ ihe kasị nkịtị ụdị nnyefe. Nje penetrates na mucous membranes na microdamages na akpụkpọ. Ụdị mmekọahụ na kọntaktị na-emekarị anaghị egwu a ọrụ pụrụ iche. The ojiji nke mgbochi gbochie afọ (condom) ebelata ihe ize ndụ nke ofufe, ma anaghị belata ya efu.
2. Transfusion (mmịnye ọbara, eze manipulations).
3. Ezinụlọ. N'ihi na ọrịa site kwa ụbọchị mkpa nnọọ nso na kọntaktị na onye ọrịa. Ọ na-adịghị ekwe nnyefe via akwa nhicha, ọsọ ezinụlọ ihe, iji a aguba ma ọ bụ atu.
4. Transplacental (nne-nyefe ozugbo na nwa ebu n'afọ).
5. Professional. Mbụ niile, ọ na-echegbu onye ahụ ike ndị ọkachamara ndị na-na mgbe niile zutere mmiri ahụ (ọbara, semen, asu). Ofufe Ọrịa bụ omume na obstetrics, ịwa ahụ adọ, otopsii.

Ọ bụla na kọntaktị na a onye na-oria na neurosyphilis, mgbe nile na-eburu ihe iyi egwu.

adakarị picture

Mgbaàmà nke neurosyphilis nwere ike akpọ ma ọ bụ na-ehichapu, mgbe ọrịa bụ na n'oge ogbo nke development. Ụfọdụ n'ime ndị nkịtị mgbaàmà e ji mara nke ọrịa, ndị dọkịta kwuru na ntighari isi ọwụwa, ike ọgwụgwụ, nkụnwụ nke aka na ụkwụ.

Ọkachamara iche n'oge, mbubreyo na congenital variant nke ọrịa. First mepụtara maka ọtụtụ afọ mgbe ọrịa. Ma ọ bụghị ya na-akpọ mesenchymal e isi aka na-enweghị nchịkwa na usoro arịa na ụbụrụ membranes. Mbubreyo ụdị daa ọrịa ayarade onwe ke afọ ise kemgbe penetration nke Treponema pallidum ke idem. Ọ na-esonyere a lesion nke akwara sel emep uta eri. Congenital neurosyphilis eto ka a n'ihi nke transplacental nnyefe nke ibute ọrịa site nne nwa ebu n'afọ na doro anya n'ime akpa ọnwa ole na ole nke ndụ.

The n'oge neurosyphilis

Nke a na ụdị nke ọrịa na-emekarị na-amalite n'ime 2-5 afọ mgbe penetration nke ibute ọrịa ke idem. Nke a ọnọdụ na-esonyere a lesion nke ụbụrụ membranes na ọbara arịa. Ya isi ngosipụta bụ syphilitic meningitis, a syphilis na latent neurosyphilis. Mgbaàmà na ihe ịrịba ama e ji mara onye nke ọ bụla ụdị, atụle N'ịkọwakwu.

1. Asymptomatic (latent) neurosyphilis nwere ike na-akpọ a "random" chọta. Na ọnọdụ a, nke e ji mara mgbaàmà na-abụghị hụrụ, na nchoputa nwere ike ike ike naanị site a mgbanwe ke mejupụtara nke mmanya.
2. Syphilitic meningitis esiwak chọpụtara na-eto eto. Otu n'ime ihe ndị mbụ mgbaàmà nwere ike mata ọgbụgbọ na vomiting, oké isi ọwụwa. The ahu okpomọkụ adahade nnọọ adịkarịghị. Ekwe Omume itinye aka na-enweghị nchịkwa na usoro nke cranial irighiri akwara na gosipụtara anya isi na mmepe nke sensorineural ntị ọnwụ.
3. A syphilis e ji isi ọbara na-ụbụrụ. Clinical daa ọrịa gosipụtara sensory disturbances, mụbara na-aghọ nkọ, na-ebelata ntị ma na ebe nchekwa impairment. Enweghị adọ ọgwụgwọ pụrụ iduga ischemic ọrịa strok. Ọ na-adịkarị na-kpọkwasịwo oké isi ọwụwa, ụra impairment, na o kwere omume ọdịdọ.

mbubreyo neurosyphilis

Nke a daa ọrịa na-ekewa n'ime ọtụtụ iche:

• Progressive mkpọnwụ.
• Tabes dorsalis.
• Gummy neurosyphilis.
• Atrophy nke optic akwara.
• Meningovascular neurosyphilis (mgbaàmà ndị yiri ụdị mbụ nke ọrịa).

Mgbe ọ na-abịa na-aga n'ihu mkpọnwụ, na-agụnye-adịghị ala ala meningoencephalitis. Ọ na-emekarị na-amalite mgbe 5-15 afọ mgbe ọrịa na syphilis. Isi kpatara nke a ụdị ọrịa - icha mmirimmiri treponemes penetration n'ime mkpụrụ ndụ ụbụrụ na ha ụdi mbibi. Ná mmalite, ọrịa na-ahụrụ mgbanwe nke elu ụjọ ọrụ (arịa ọrịa nke uche na ebe nchekwa, ogwe). Dị ka progression nke ọrịa na-isonyere nsogbu uche (ịda mbà n'obi, delusions na ịmụ anya arọ nrọ). N'etiti akwara ozi mgbaàmà nwere ike kwuru tremor ire, dysarthria na mgbanwe ji aka dee. The ọrịa amalite ngwa ngwa ma n'ime ọnwa ole na ole bụ na-egbu egbu.

Ọ bụrụ na ọ na-emetụta ndị dorsal mgbọrọgwụ na spinal udọ, ndị dọkịta na-ekwu tabes dorsalis. Clinical daa ọrịa na-egosipụta onwe n'ụdị ọnwụ nke ụkwụ na-aghọ nkọ, akwusighi na Romberg ọnọdụ. Dị ka a N'ihi nke na-agbanwe agbanwe mmadụ gait. Ọ bụ omume ntoputa nke optic akwara atrophy. Ọzọ e ji mara ọrịa bụ trophic onya.

Atrophy nke na optic akwara , mgbe ụfọdụ, na-eme dị ka otu nọọrọ onwe ha ụdị ọrịa dị ka neurosyphilis. Ndị na-esi nke ọrịa budata ebelata àgwà nke ndụ. The mbụ enweghị nchịkwa usoro emetụta naanị onye anya, ma mgbe a ka ọ na-aghọ bilateral. Belata visual acuity. Na-anọghị nke na-adọ ọgwụgwọ nke na-emepe emepe ìsì.

Gummy neurosyphilis. Gummi bụ ahazi formations nke na-guzobere n'ihi nke mbufụt mere site treponema. Ha na-emetụta ụbụrụ na ọgidigi azụ, irighiri akwara compressing. Clinical daa ọrịa na-egosipụta site mkpọnwụ nke aka na ụkwụ na pelvic ọrịa.

congenital neurosyphilis

Nke a na ụdị ọrịa a na-chọpụtara nnọọ adịkarịghị. N'oge ime, expectant ọhụrụ nne ugboro ugboro n'ịnwụ ule mata-efe efe. Ọ bụrụ na intrauterine ọrịa ka mere, ọ bụ nnọọ mfe ịghọta. The adakarị picture e ji otu ihe mgbaàmà dị ka nke okenye ọrịa, ma e wezụga tabes dorsalis.

Congenital ụdị ọrịa nwere pụrụ iche ihe mgbaàmà. Nke a na-akpọ hydrocephalus na Hutchinson chi atọ n'ime: ntị ochichi, keratitis na deformation nke elu incisors. Bịara n'Ezi Oge ọgwụgwọ nwere ike ịkwụsị ọrịa usoro, ma akwara ozi mgbaàmà ndị ahụ adịgide ná ndụ.

nchoputa nke neurosyphilis

Gịnị bụ neurosyphilis, a gwara anyị. Olee otú iji gosi na ọrịa? Eziokwu nchoputa nwere ike dabere na atọ isi ibiere: ndị e ji mara na-adakarị picture, pụta nke ule syphilis, ịmata mgbanwe mejupụtara nke cerebrospinal ọmụmụ. Ezigbo ntule nke ọrịa na-arịa bụ nanị nti mgbe akwara ozi nnyocha.

Banyere laabu ule, ha na-rụrụ emejuputara. Mgbe ụfọdụ, a ule ugboro ugboro. The kasị ihe ọmụma laabu achọpụta ọrịa ụzọ gụnyere RPR-analysis RIBT, RIF, na njirimara nke na-efe efe gị n'ụlọnga ke ọdịnaya nke na-emetụta anụ.

Na enweghị akpọ mgbaàmà rụrụ lumbar mgbapu. Neurosyphilis na CSF show elu etoju nke protein, na causative gị n'ụlọnga nke ọrịa - icha mmirimmiri treponemu.

MRI na CT Doppler nke ọgidigi azụ na-kenyere nile ọrịa na-enyo enyo na neurosyphilis. Diagnosis site pụrụ iche apparatuses ekpughe atrophy hydrocephalus na ụbụrụ umi.

Esi merie neurosyphilis?

Ọgwụgwọ nke n'oge iche nke ọrịa dabeere eme ihe ike ike ọgwụ nje ọgwụ. N'ihi nke a, preparations nke penicillin na cephalosporin usoro. A, ọgwụ bụ mgbagwoju na-agụnye iji ihe ọtụtụ ọgwụ na n'otu oge ahụ. Ndị na-adị atụmatụ: "penisilini", "Probenecid", "Ceftriaxone". All ọgwụ ọjọọ na-ndinọ intravenously. Ọgwụ "penisilini" na-eme ka ndị spinal kanaal. The ọgwụgwọ na-emekarị ekwupụtakwa maka izu abụọ. Mgbe nke ahụ gasịrị, onye ọrịa dabara a re-nnyocha, nke i nwere ike na-ekpe ikpe na-arụpụta nke eziokwu ma ọ bụ na o kwere omume iji merie neurosyphilis. Ọgwụgwọ ogologo ma ọ bụrụ na ndị cerebrospinal ọmụmụ ngosi icha mmirimmiri treponemu.

N'ụbọchị mbụ nke usoro ọgwụ nwere ike njọ akwara ozi mgbaàmà (isi ọwụwa, ịrị elu okpomọkụ, tachycardia). N'ọnọdụ dị otú ahụ, usoro ọgwụgwọ complemented mgbochi mkpali ọgwụ ọjọọ na corticosteroids.

Mbuso mbubreyo iche nke neurosyphilis eji ọgwụ ọjọọ eme ihe na arsenic na bismuth, ji elu toxicity.

Amụma na ya pụta

Early iche nke neurosyphilis anabata nke ọma ọgwụgwọ, full mgbake bụ na o kwere omume. Mgbe ụfọdụ, nọgidere na-akpọ mmapụta mmetụta n'ụdị paresis na dysarthria na nwere ike ime ka nsogbu.

Mgbe e mesịrị iche nke daa ọrịa agụghị oké na ọgwụ ọgwụ. Akwara ozi mgbaàmà agbasaghị ịnọgide na-enwe ndidi n'ihi na ndụ.

Progressive Mkpọnwụ a afọ ole na ole gara aga rụpụtara a na-egbu egbu na ya pụta. Taa, na ojiji nke ọgwụ nje penicillin enye ohere mitigate mpụta ìhè nke mgbaàmà na ngwa ngwa neurosyphilis.

Photo nke ọrịa na a nchoputa na mgbe omume ọmụmụ-ekwe ka anyị ghọta ihe iyi egwu daa ọrịa na-ahụ. Ọ bụ ya mere onye ọ bụla kwesịrị ịma otú iji gbochie ọrịa a.

mgbochi

Iji gbochie ọrịa, ndị dọkịta nwere ike ikwu na ịgbahapụ n'echeghị echiche mmekọahụ. Ọ bụ na uche pụrụ iche na-adị ọcha. People nje Treponema pallidum, on a amanyere bụ iwu nke ndabere kwesịrị ịbịa mgbochi nnyocha site a ọkà mmụta ọrịa akwara.

Gịnị bụ neurosyphilis? Nke a bụ a dị ize ndụ ọrịa ji CNS. Na-anọghị nke na-adọ ọgwụgwọ kwesiri ịzụlite-eyi ndụ egwu nsogbu, nke na-emetụta àgwà nke ndụ, na mgbe ụfọdụ iduga ọnwụ. Ya mere, ị kwesịrị ị na-eleghara mgbochi nke ọrịa, na mgbe ọrịa ozugbo-achọ ọgwụ anya.