Kedu ihe analogue nke "Pregnil" iji mee ihe? Nkọwa nke analogues nke "Pregnil"

A na-eji "nyocha" mee ihe n'ịgwọ infertility n'ime ụmụ nwanyị, imepụ nwa ebu n'afọ, iyi egwu nke ime ime onwe ya, nakwa maka ịmịnye ọbara nke ovaries, ịmalite ịmụ nwa na mmụba nke estrogens. Ojiji ya dị irè n'ime atụmatụ nke ọgwụgwọ ngbanwere nke hormone na-egbuke egbuke iji kpalite maturation nke erulu.

Ntuba maka ojiji nke nwoke na-egbu oge na mmekorita mmekorita nke e jikọtara ya na hypofunction nke iyi egwu mmekọahụ, cryptorchidism, spermatogenesis na-adịghị mma. Chee echiche banyere okwu "Pregnil" a ma ama na isiokwu a.

Nkọwa nke ọgwụ "Pregnil"

"Pregnil" na-agụnye chorionic gonadotropin (HCG), mmadụ. Mmiri a na-amalite ịmịpụta anụ ahụ mgbe embrayo na-agwụcha. HG nwere arụ ọrụ na-akpali akpali ma na-arụ ọrụ nke ọma, na-eme ka nlezigharị nke estrogens dịkwuo elu ma na-ebido usoro ịzụ nwa. Ọzọ na-akwado ọrụ ọrụ nke ahụ na-acha ahụ edo tupu emepụta estrogen na procentterone site na placenta.

Ojiji nke gonadotropin chooicous choro ọ bụghị nanị na-eme ka nlezianya nke estrogens na-emegharị site na ovaries, kamakwa na-eme ka ọkpụkpụ pụta, na-eme ka ụbụrụ na-esote ọkpụkpụ ahụ na-aga n'ihu.

Iji ọgwụ ọjọọ eme ihe bụ HG kachasị dị irè n'ime atụmatụ ahụ na nhọpụta nke homone na-akpali agụụ mmekọahụ.

Atụmatụ Ahụike

"Nchọpụta" (okwu nke "Pregnil" dị na otu onodi ogwu) dị na dosages nke 1500 na 5000 MO. Eji ya mee ihe.

Na ọgwụgwọ nke infertility n'ime ụmụ nwanyị, a na-akwado otu nchịkwa nke 5,000-10,000 IU mgbe ọ gwụchara usoro ọgwụ FSH (hormone na-akpali akpali) ma ọ bụ CHMH (manopausal gonadotropin).

Tupu ntụpọ ahụ, maka nchịkwa nchịkwa nke ovaries, mgbe njedebe nke ọgwụgwọ gasịrị, 5000 IU na-arụ ọrụ.

A na-akwado usoro ọhụụ site na injections cyclic na nhazi nke 1000 ruo 3000 MO kwa ụbọchị atọ-ugboro atọ.

N'ime ụmụ nwoke, a na-eji ya maka hypofunction nke iyi egwu mmekọahụ na maka mmebi nke spermatogenesis na dosages nke 1000 ruo 2000 MO ọtụtụ ugboro n'izu (a pụrụ iji okwu ahụ nke "Pregnil" mee otu ụzọ ahụ).

Mgbe ị na-emeso cryptorchidism na ụmụ, a na-eji ọgwụ ahụ eme ihe ugboro abụọ n'izu, a na-atụ aro ya:

- ruo afọ 2 - 250 MO;

- ruo afọ isii, mee ka 500 ruo 1000 MO;

- mgbe afọ 6 gasịrị - 1500 MO.

Anyị nyochara atụmatụ nke itinye ọgwụ ahụ. Mana ọ kachasị mma ịkpọtụrụ dọkịta tupu ịmalite ọgwụgwọ ma nye ya ọgwụ.

Analogues nke "Pregnil"

Kedu ihe analogues nke Pregnil? N'ezie, enwere otutu n'ime ha, enwere ọgwụ ọjọọ dị ọnụ ala, ndị dị ọnụ.

"Gonadotropin chorionic"

"Gonadotropin chorionic" bu uzo di ala nke "Pregnil". Na-emepụta ihe dịka 500; 1000; 1500 nkeji. A na-eji ya na intramuscularly. A na-ede ya n'usoro ihe dị ka 1500 ED n'otu ụbọchị ma ọ bụ 3000 ED 2-3 ugboro n'izu n'ịgwọ infertility na ụmụ nwanyị. Na ọgwụgwọ nke mmekọahụ infantilism inye si 500 na 1000 IU otu ugboro n'izu, ọmụmụ ruo 2 ọnwa. A na-enye ụmụ ụmụaka 500-1000 MO ruo afọ iri, mgbe ahụ - maka 1500 ED ruo otu ọnwa na usoro ọmụmụ ugboro ugboro. Nke ahụ bụ, nkwadebe "Pregnil" nwere ihe analogues dị ala.

Ovitrel

"Ovitrel" nwere choriomonadotropin alfa. Eji ya mee ihe na 250 mcg (6500 IU). A na-etinye ya n'ọrụ. Na-eme ka ọkpụkpụ akpụkpọ ahụ pụta, na-eme ka ụbụrụ nke na-akpụ akpụ na-akpụ akpụ. 250 mcg dị ka mpaghara 5000 nke gonadotropin choro mmadụ. Mgbe ọ na-akpali ụmụ ovaries ma nweta superovulation, a na-eji 250 μg mee ihe, mgbe a gwọchara ọgwụ na ọgwụ ndị homopausal ma ọ bụ na-akpali agụụ mmekọahụ. N'iji ọgwụgwọ na-eme ihe, a na-edozi dose 1 ụbọchị tupu enwe mmekọahụ.

"Horagon"

Ihe omuma nke ozo. Ejiri ihe dị ka 1500 na 5000 MO. A na-enye ya na intramuscularly. A na-eji ya maka dysmenorrhea, hypoplasia nke na-enwe mmekọahụ, mmekọahụ infantilism maka nzube nke ịbawanye mmepe mmekọahụ, iyi egwu nke ime na-enweghị mmerụ, maka ịmepụta superovulation. Maka ntinye nke superovulation ka a na-ede n'usoro nke 5000 ruo 10 000 MO n'otu oge. Na ọgwụgwọ nke abortions mgbe nile, a na-atụ aro iji ụbọchị mbụ nke ime ime ruo izu 14, ugboro abụọ n'izu maka 10,000 MO. Ọgwụgwọ hypogonadism gụnyere nhazi nke 1500 na 6000 IU otu ugboro n'izu. A na-emeso etrogen deficiency na ụmụ nwoke na HCG n'otu ugboro kwa izu abụọ, maka ọnwa atọ.

"Horyomon"

Emepụta na usoro onunu ogugu nke 5000 IU / ml, maka injection intramuscular. Enwere ezigbo irè na ọgwụ amorrhea na usoro mgbanwe ndụ. A na-eji ya eme ihe na manopausal gonadotropin (75 MO) ruo ụbọchị 10 ma ọ bụ subcutaneously ma ọ bụ intramuscularly iji mụbaa eriri estrogen. Mgbe mkpịrịgwụ nke tozuru etozu na-apụta na ultrasound maka ịmịpụta nwa, site na 5000 ruo 10 000 MO "Choriomon" na-injected. A na-enye ọgwụ ahụ ruo ụbọchị 1-2 mgbe ọghachị ikpeazụ nke CHMG ma ọ bụ FSH. A na-atụ aro omume mmekọahụ kwa ụbọchị tupu a mụọ nwa.

Enweghị afọ ojuju n'ihi enweghị oke nke ngọngọ luteal nke "Chorion" ji mee ihe maka MO 5000 na iri abụọ na abụọ, nke 23 na nke 25 nke oge ahụ.

"Ọkwa"

"Prophase" bu okwu nke "Pregnil 5000". Ejiri ya mee ihe na 2000 na 5000 MO. A na-eji ya na intramuscularly. A na-eme ọgwụ nke infertility site na mmalite nke MO,000 10,000 n'etiti etiti ahụ, mgbe ọgwụgwọ na HMG ma ọ bụ FSH. Maka ntinye nke superovulation, a na-ede 10,000 IU kwa ụbọchị tupu nchịkọta ovum. N'adịghị ụbụrụ ahụ, a na - atụ aro mmalite nke 5000 MO, na nke ise na nke itoolu mgbe ọ gasịrị. "Prophase" dị nnọọ irè n'ịgwọ ọrịa nke ịmalite ime ọpụpụ. A na-eji ya maka 10,000 IU na mbido mbụ, mgbe ahụ - 5000 IU ugboro abụọ n'izu ruo izu 14.

Contraindications

Contraindications na iji ọgwụ ọjọọ eme ihe HG:

- Postmenopause.

- Ọkpụkpụ nke na-emepụta ụbụrụ nke mmekọahụ.

- Tumors nke hypothalamus na pituitary gland.

- Tumors nke akpanwa, na-ekwekọghị n'afọ ime.

- Thrombophlebitis.

- Hypothyroidism.

- Tubal ime akụkọ ihe mere eme maka ọnwa atọ tupu ọgwụ.

- Polycystic ovary.

- Oge nsị.

Mmetụta dị n'akụkụ

Mmetụta dị iche iche site n'iji ọgwụ gonadotropin mmadụ eme ihe:

- Nwee obi mgbawa, inwe mmetụta uche, isi ọwụwa, nchegbu.

- Nsogbu Dyspeptic (ọgbụgbọ, vomiting).

- Mmetụta nke ọnyá.

- Gynecomastia n'ime ụmụ nwoke.

- Rash, hives.

- ọrịa nke ovarian hyperstimulation.

- Ọdịdị nwa oge nke mkpịsị ọbara, nkwụsị ihe dị njọ.

- Mmebe ọrụ nke pituitary gland.

- Mbelata nke olu nke ikesa ọbara (hypovolemia).

- Ịchịkọta ọbara n'ime oghere abdominal.

- Thromboembolism.

- Ime otutu ime.

- Ntuchi mmiri, nke a kpọrọ, ọzịza nkịtị.

Otu okwu nke "Pregnil 1500" adịghị mma ma ọ bụrụ na enweghi nsogbu na mmepe nke akpanwa, ngwa ngwa na ikpu, ikpo ọkụ n'ime tublopis, ọdịda isi nke ovaries, na etuto ukwu fibrotic n'ime akpanwa.

Usoro ọgwụgwọ nile bụ n'okpuru nlekọta nke ọkachamara ọkachamara na nchịkwa nyocha ahụ, eji ọgwụ ndị a eme ihe n'ụlọ na-adịghị anakwere, ọ pụkwara iduga na ọrịa ndị na-enweghị atụ.

A ghaghị ịgwọ ọrịa infertility na-achịkwa na-achịkwa ọganihu follicular na nyocha mgbe nile nke ọnụọgụ ahụ.

Nyocha kwa ụbọchị nke concentradio estradiol dị mkpa. Na mgbaàmà nke hyperstimulation a na-achọghị na ovaries, ọgwụgwọ na gonadotropin chorionic akwụsị ozugbo.

Anyị atụlewo ihe analogues na nkwadebe "Pregnil", ntụziaka maka iji ha na-akọwa.