"Metformin" ọgwụ. Nyocha. Ajuju

"Metformin" ọgwụ na-ezo aka na ndị isi hypoglycemic oral nke nnukwu groupide. Mgbe ndị ọrịa na-arịa ọrịa shuga, ọgwụ ahụ na-ebelata glucose n'ime ọbara site n'imebi gluconeogenesis n'ime imeju, yana ịbelata absorption ya na usoro nsị. N'ihi mmụba nke insulin n'ahụ anụ ahụ, ejiji (glucose) emewanye. Agwọ ọrịa "Metformin" (kwuru ndị ọkachamara na nke a show) nwere mmetụta na lipid metabolism. The ọgwụ na-enyere aka belata triglycerides, LDL cholesterol na ọbara. Ngwá ọgwụ ahụ na-ebelata (na-eme ka ahụ dịkwuo njọ). Mgbe ịbanye n'ime, absorption nke onye ọrụ ahụ bụ nke 48-52%. Na iri nri otu ihe oriri nri na-ebelata. Ogologo kachasị elu ruru awa 2-3 mgbe e mesịrị. A na-ejikọta ọgwụ ahụ n'ụzọ dị mfe na protein protein plasma, na-eme ka ọ ghara ịdị ike.

Ihe Metformin pụtara. Ngwa

A na-enye ọgwụ maka ụdị ọrịa shuga abụọ (shuga) nke ndị okenye (karịsịa ndị na-ata ahụhụ n'oké ibu) na enweghi mmetụta nke ịmalite ahụ ike, usoro ọgwụgwọ. "Metformin" ọgwụ "(ihe ndị dọkịta na-agba akaebe na nke a) nwere ike iji dịka monotherapy ma ọ bụ dịka akụkụ nke ọgwụ ọgwụ hypoglycemic ma obu insulin. A na-enye ọgwụ maka ụmụaka ndị dị afọ iri na ụdị ọrịa shuga 2 dị ka monotherapy ma ọ bụ dịka akụkụ nke ọgwụgwọ siri ike.

Contraindications

Agwọ ọrịa "Metformin" (reviews nke dọkịta ná ntị banyere nke a) na-ekwesịghị ime ma ọ bụrụ a ọrịa Coma, precoma, ketoacidosis, hypersensitivity. Contraindications gụnyere ọnọdụ nke nnukwu ọdịdị nke na-etolite na ọ ga-abụ na ọ ga-abụ mmalite nke nkwụsị aka. A naghị atụ aro ọgwụ na stepo hypoxia, na mmiri agwụ, ọrịa bronchopulmonary, ọnya na-efe efe na akụrụ, nkwụsị, ujo, imeju umeji, nnukwu mmanya na-egbu egbu, lactic acidosis, gụnyere akụkọ ihe mere eme. A naghị atụ aro ọgwụ ahụ iji gosiputa mgbaàmà nke ọrịa ọrịa na-adịghị ala ala ma ọ bụ nnukwu nke nwere ike ịkpasu ahụ hypoxia anụ ahụ. Ọnọdụ ndị dị otú ahụ gụnyere nnukwu infarction myocardial, akụkụ iku ume, nkụda obi na ndị ọzọ. Ọ bụghị prescribers n'okpuru afọ iri afọ, n'okpuru a belatara kalori nri. A na-akpachara anya na ịgwọ ndị agadi (ihe karịrị afọ 60) ndị ọrịa na-arụ ọrụ na nrụgide anụ ahụ.

Mmetụta dị n'akụkụ

"Metformin" ọgwụ (ọkachamara ọkachamara na-egosi nke a) nwere ike iduga n'ịka njọ nke agụụ, vomiting, ọgbụgbọ, nsogbu nro, afọ ọsịsa, ọkụ ọkụ, erythema, ihe ngosi ahụ na-ekesa ahụ. Iji mee ka ahụ dịkwuo mma, ọ na-atụ aro ka ị jiri nwayọọ nwayọọ mụbaa ọgwụ ahụ. N'ihe gbasara ọgwụgwọ, ọnyá dị n'ime afọ, ịba ọcha n'anya, imebi iwu nke imeju. Dị ka a na-achị, mgbe a kpochapụrụ nkà mmụta ọgwụ ahụ, a ga-esi na ya pụta. N'iburu ihe eji eme ogologo oge, hypovitaminosis B12, folic acid nwere ike ịmalite.