Mụbara prolactin: akpata, mgbaàmà, ọgwụgwọ, pụta

Ọ bụrụ na elu hormone prolactin, ndị nsogbu n'obi ịhụ nsọ okirikiri na mmiri ọgwụ itule, na e nwere infertility ma ọ bụ nsogbu na-ebu a na nwa. Ya mere, ndị inyom kwesịrị ikpebi na ya ozo na ọbara n'oge ime atụmatụ.

Prolactin na-emepụta site na pituitary gland - endocrine gland dị na ụbụrụ. Hypothalamus akara usoro a. Ahụ ya na ndị dị nnọọ mwute na mpụga ihe. Ya mere, elu prolactin nwere ike ịbụ n'ihi ndị na-esonụ:

• ọgwụ ọjọọ;

• gbasara akụrụ odida;

• nchegbu;

• imeju;

• rahụ ụra;

• Cushing si syndrome;

• Addison ọrịa ;

• acromegaly;

• sarcoidosis;

• neyrotuberkulez;

• ozizi;

• na ọbara oge;

• ime;

• ọnụ ara mmalite;

• ara;

• mmekọahụ;

• Nkụnwụ;

• mmerụ na ịwa ahụ na obi.

N'oge dị iche iche nke okirikiri nke hormone larịị ke ọbara dịgasị si 6 na 28 and / ml. Iji nweta pụrụ ịdabere na ya pụta ike iwere mgbe analysis of ụra ma ọ bụ na usoro. The secretion nke prolactin etịbe pulsed, ugboro dabere na-adọ nke okirikiri. E nwekwara kwa fluctuations nke ya dị larịị, n'ihi na ihe atụ, mgbe aza hormone ịta nta. Mgbe ụra ya secretion na-abawanye na-etolite a nrọ.

Otu-atọ nke ọrịa ndị na-agwụla prolactin, hụrụ pituitary adenoma. Ọ bụrụ na ya size bụ nnukwu, bụ mmiri ọgwụ larịị bụ ihe karịrị 100 and / ml. Lower udu pụrụ microadenomas na obere nha, bụghị achọpụtara site X-ray.

The kasị ihe ọmụma usoro maka nchoputa nke pituitary etuto ahụ - a MRI. Ọ dị mkpa na-agafe na atụmatụ nke nwa, ọ bụrụ na e enyo nke ihe adenoma, dị ka nnukwu akpụ pụrụ iso kpata nsogbu.

Akụkụ pituitary microadenomas adịghị gafere 1 cm. Ha na-eto dị nnọọ nwayọọ nwayọọ na na-na-benign. Macroadenomas n'obosara ukwuu karịa 1 cm. Ha na-ebu isi ọwụwa, mgbanwe visual ubi na mgbe ụfọdụ zuru ezu ọnwụ nke ya. N'elu nchọpụta macroadenoma dị mkpa oge nke a neurosurgeon. Ọ na-eme ka a mkpebi banyere ịwa ahụ. N'oge ime microadenomas emekarị adịghị agbanwe agbanwe, ma etuto ahụ nke nnukwu size na 20% nke ikpe na-eto eto.

Prolactin na-ugboro ugboro elu na gbasara akụrụ odida (adịghị ala ala). Mgbe akụrụ transplantation a normalisation nke ya secretion.

Ọ bụrụ na prolactin na-elu, na ihe mgbaru ọsọ na ọgwụgwọ nke na-esonụ:

• belata ya larịị;

• weghachi okirikiri;

• belata akpụ size, ma ọ bụrụ na ugbu a.

Otu n'ime ihe ndị ọgwụ ọjọọ eme ihe Lower hormone - bụ Parlodel, nke bụ a dopamine agonist. Ọ na-egbochi ahụ secretion nke prolactin site na-akpali akpali na-anabata ya na ụbụrụ. Dose na-adabere na ogo na ọdịdị nke ọrịa ahụ. Mgbe iwebata bromocriptine okirikiri a na-weghachiri eweghachi mgbe nkezi nke 7 izu. Ọ bụ ezie na ụfọdụ ndị ọrịa ya emee na a ụbọchị ole na ole.

Bromocriptine emekarị buru ọtụtụ ugboro n'ụbọchị. ndị dose nwere ike ụba ma ọ bụrụ na ọ dị mkpa. Ọgwụgwọ kwesịrị adịru ọtụtụ cycles mgbe mweghachi nke ịhụ nsọ gbochie nlọghachite. Mmetụta nke bromocriptine:

• ike ọgwụgwụ;

• dizziness;

• isi ọwụwa;

• vomiting;

• akọrọ ọnụ;

• ọgbụgbọ.

Ntọt prolactin nwere ike ime ka hypothyroidism. Ịnata Gomonov na nke a na-eduga ná normalisation nke ya larịị.

Egosi maka prolactin nyochaa ndị na-esonụ:

• osteoporosis;

• gynecomastia;

• ala potency na libido;

• hirsutism;

• ibu oké ibu;

• Arọ njedebe;

• lactation ọrịa;

• infertility;

• anovulation;

• ara;

• nhọrọ nke ọnụ ara;

• amenorrhea, oligomenorrhea;

• cyclic ara mgbu.

N'ihi ya, prolactin mụbara, ọtụtụ mgbe n'ihi pituitary adenomas. Ke adianade do, a na-akpatakarị nke elu ịta bụ hypothyroidism. The ụba ịta nke prolactin na-eduga ná emeghasịkwa nke ịhụ nsọ ọrụ na enweghị ovulation, otú ahụ tụụrụ ime na ịmụ nwa na-aghọ ihe fọrọ agaghị ekwe omume. Ọgwụgwọ mejupụtara mbenata ya larịị, n'ikpochapụ ọrịa na-akpata na mgbake okirikiri.