Ọgwụ "famotidine": reviews ndị dọkịta na nke

Gastric hyperacidity akwalite bụghị nanị ọdịdị nke wetara sensations, ma mmepe nke oké njọ ọrịa ndị dị ka ozize na mucosal onya. Ya mere, ke akpa ihe ịrịba ama nke ndị dị otú ahụ ndiiche ga ozugbo ịkpọ onye dọkịta, a gastroenterologist.

The uru emepụta taa, ọtụtụ dị iche iche ọgwụ ọjọọ nke inhibit secretion nke hydrochloric acid. Ndị kasị oké ọnụ na inweta n'aka na-agụnye ọgwụ "famotidine". Nyocha nke dọkịta kwuru na ọgwụ ga-ọkọnọ n'okpuru.

ntọhapụ ụdị, nkwakọ, nkọwa na mejupụtara

Nkwadebe "nke famotidine" na-agbala n'ụdị obere pellets. Ha na-okirikiri na lenticular udi, na akpụkpọ odo ma ọ bụ aja aja.

The n'ọrụ mgwa nke a gị n'ụlọnga bụ famotidine. E wezụga ya, ngwaahịa nwere inyeaka mmiri ka magnesium stearate, ọka starch, microcrystalline cellulose, sịlịkọn dioxide, talc, na sodium croscarmellose.

Na-akwanyere ndị shei, ọ mejupụtara hypromellose, talc, Macrogol 6000, titanium dioxide (E171) na aja aja na ígwè oxide ink.

Drug "famotidine" foto na-e kwuru n'isiokwu a bụ ndị dị na ọnya Ukwu, nke na-ẹdude ke akwụkwọ katọn.

Pharmacology nke mgbochi ọnyá afọ ọgwụ

Gịnị dị ịrịba ama iji ọgwụ "famotidine"? Nyocha kọrọ na ọ bụ a asọmpi na-eti ọkpọ nke histamine. Emetụta histamine H2-anabata nke parietal mkpụrụ ndụ, ọ na-ebelata secretion nke hydrochloric acid, rata site iche iche stimuli. Ọ na-belatara basal mmepụta. Mgbe nke a mere ka a nta ruo n'ókè secretion mgbochi mere pepsinogen.

Ịnakwere ọgwụ n'okpuru nyochaa anaghị agbanwe ihe na-etoju nke gastrin ke iyịp. Na oge nke ya edinam n'elu otu ngwa dose-dabere na bụ 12-25 awa.

The kinetics nke ọgwụ

Ebe absorption nke ọgwụ "famotidine"? Nyocha na-ekwu na mgbe onu ochichi nke ọgwụ na-ngwa ngwa etinye obi gị dum na eriri afọ tract. Ọzọkwa, ya elu ịta a na-enweta n'ime ọbara maka 1-3 awa.

Communication plasma protein bụ 17-20%. A na nkà mmụta ọgwụ ọ na-anyụpụ na mmiri ara na penetrates site na placental mgbochi.

Odika 30-37% nke famotidine na-metabolized na imeju. Ya mmepụta anyụpụ site na akụrụ ya.

na-agba akaebe

Gịnị na-egosi na ọgwụ ọjọọ, "famotidine"? The ojiji nke a gị n'ụlọnga nwere mmetụta dị mma n'ebe ala nke digestive tract na:

• erosive gastroduodenitis;
• ọnyá afọ na mgbochi nke ya nlọghachite;
• ọtọ dyspepsia ;
• symptomatic na nrụgide ọnyá afọ;
• reflux esophagitis;
• multiple endocrine adenomatosis;
• Zollinger-Ellison syndrome;
• systemic mastocytosis;
• mgbochi nke nlọghachi azụ nke na-agba ọbara na postoperative oge;
• Prevention of ọchịchọ nke gastric ihe ọṅụṅụ na ndị mmadụ emume ịwa n'okpuru general ná Nkụnwụ (na Mendelson si syndrome) ;
• mgbochi nke ọchịchọ pneumonitis;
• na retrosternal dyspepsia ma ọ bụ epigastric mgbu nke ime abalị ma ọ bụ mgbe a nri.

Contraindications na-enweta mgbochi ọnyá mbadamba

Mgbe ị na-ekwesịghị iji Erere "famotidine"? Nyocha ikwu na contraindications nke a ọgwụ na-na-esonụ na-ekwu:

• ara;
• ime;
• afọ atọ na afọ na a arọ ahụ ruo 20 n'arọ;
• hypersensitivity ka famotidine na ndị ọzọ na blockers nke histamine H2-anabata.

Ihe ókè ịkpachara anya bụ a na nkà mmụta ọgwụ kenyere immunosuppression, imeju ma ọ bụ akụrụ odida na ụmụ na imeju nke imeju encephalopathy (portosystemic).

Olee otú m ga-ewe "famotidine" mbadamba?

Nyocha kọrọ na ọgwụ a na-e jikwa ọnụ, na-enweghị ịta.

Okenye na ọnyá nke digestive tract na erosive gastroduodenitis inye 20 mg ugboro abụọ n'ụbọchị. Ọ bụrụ na chọrọ, kwa ụbọchị onunu ogwu nwere ike mụbara 80 ma ọ bụ 160 mg. Nke a ọgwụ ga-adịru dịkarịa ala 4-8 izu.

Na ọnụnọ nke dyspepsia, a na-ejikọta na ụba secretion nke afo, ọrịa na-ndinọ 20 mg nke iji ọgwụ otu ugboro n'ụbọchị.

N'ihi mgbochi nke ọnyá afọ Nlọghachi ọgwụ ọjọọ 20 mg kwa ụbọchị na alakpu ụra.

Mgbe Zollinger-Ellison syndrome na onunu ogwu nke ọgwụ na oge nke ọgwụ ọmụmụ na-setịpụrụ n'otu n'otu. The mbụ dose of agwọ ọrịa mgbe ndị dị otú ahụ nchoputa na-abụkarị 20 mg. Ọ na-e ọ bụla 6 awa. Ọ bụrụ na ọ dị mkpa, ya nwere ike mụbara ka 160 mg.

Mgbe refpyuks esophagitis ọgwụ ọjọọ site 20-40 mg ugboro abụọ n'ụbọchị nke isii - iri na abụọ izu.

Children karịrị afọ atọ nke ọnyá afọ na reflux esophagitis ọgwụ kenyere na ọnụego nke 2 mg / n'arọ kwa ụbọchị.

mmetụta

Gịnị mmetụta ọjọọ ndị pụta ụwa ọgwụ "famotidine"? Nyocha nke dọkịta na-egosi ndị na-esonụ omume:

• akọrọ ọnụ, ike ọgwụgwụ, vomiting, dizziness, abdominal mgbu, iro ụra, afọ ntachi, nsogbu nke agụụ, nervousness, mụbara ọrụ nke imeju enzymes, anụ ọkụ ọkụ, nnukwu pancreatitis;
• aghara, bradycardia, ịmụ anya arọ nrọ, vasculitis, pyrexia;
• arrhythmia, akọrọ anụ ahụ, belata ọbara mgbali, AV-ngọngọ;
• alopecia, leukopenia, otutu vulgaris, bịara ikiri ọhụụ, antionevrotichesky ọzịza, itching, agranulocytosis, bronchospasm;
• isi ọwụwa, ọgbụgbọ, ehighi ura, nchegbu, bloating, tinnitus, afọ ọsịsa, ịda mbà n'obi, ịba ọcha n'anya, psychosis, paresis nke ulo;
• anaphylactic ujo, hypoplasia, ngosipụta nke hypersensitivity;
• thrombocytopenia, amenorrhea, pancytopenia, hyperprolactinemia, aplasia nke ụmị ọkpụkpụ;
• gynecomastia, enweghi ike, ahụ ọkụ, ihe mgbu na nkwonkwo;
• ebelata libido, muscle mgbu, na-abawanye na urea etoju ke ọbara.

Nyocha

Ọkachamara na-ekwu na ọgwụ "famotidine" abụghị ndị kasị dị irè mgbochi ọnyá gị n'ụlọnga. N'agbanyeghị nke a, ọ na-nnọọ na-eji na ọgwụgwọ nke eriri afọ ọrịa.

Dị ka ọrịa, ha na-ekwu na ná mmalite nke ọgwụgwọ na ọgwụ na-akpa àgwà ọma. Mgbe e mesịrị, ọ na-kwụsị.