Prednisolone: ntuziaka maka ojiji, na pharmacological Njirimara

Hapụ ụdị "Prednisolone" ọgwụ: adụ ọgwụ forms - ude.

Farmsvoystva

Prednisolone bụ a dehydrogenated analogue nke hydrocortisone. Antiallergic, antiinflammatory, antiexudative na antipruritic mmetụta mgbe eji topically Ude "prednisolone" ntụziaka na-akpata a ọnụ ke kpụworo, ntọhapụ na ọrụ nke mbufụt ogbugbo (kinin, a histamine, lysosomal enzymes, prostaglandins). Ọzọkwa eru cell Mbugharị ka mkpali ebe oria a kachaa mbelata vasodilation na ụba vaskụla permeability odu ke mbufụt. Mbenata exudation bụ n'ihi na vasoconstrictor edinam nke "Prednisolone" ọgwụ ọjọọ. Manual na-egosi na ọgwụ bụ ihe immunosuppressive mmetụta site inhibiting ihe nke antigen-antibody mgbagwoju na dum n'ịkpa na mgbidi ọbara arịa na ndị na-akpata nke anabata vasculitis. The ọgwụ na-egbochi ihe nke macrophages, cytokines, lekwasịrị mkpụrụ ndụ na-eme ka mmepe nke anabata ụdị na-efe efe dermatitis. N'ihi ya nkọ T-lymphocytes na macrophages nwere ike ghara inwe ohere ka lekwasịrị mkpụrụ ndụ.

Pharmacokinetics

Mgbe ngwa nke manu-otite "Prednisolone" etinye obi gị dum na-arụsi ọrụ ike umi bụ ke n'ọbara. Na ọbara plasma prednisolone bukwanu akụkụ bụ yiri ka albumin na transcortin. Biotransformation prednisolone emee site ọxịdashọn, tumadi na imeju, ebe glucuronidation ma ọ bụ sulfation emee oxidized iche-iche. N'ụdị metabolites anyụpụ na mmamịrị na feces, a akụkụ - na unmodified ala. Prednisolone agabiga placental mgbochi obere kasịnụ, ọ nwere ike dị na mmiri ara nke nwanyi.

Prednisolone: àmà

The ọgwụ na-eji na ikpe nke:

- anabata na irritant kọntaktị dermatitis,

- eczema,

- atopic dermatitis,

- seborrheic dermatitis,

- psoriasis.

Prednisolone: ntụziaka

The ude na-etinyere na ọnya saịtị evenly 1-3 ugboro / ụbọchị. Duration ọgwụgwọ e mere site ọdịdị nke ọrịa na-emekarị ekwupụtakwa maka 8-14 ụbọchị. Ude na ọgwụgwọ nke ụmụ oge nke ọgwụgwọ a ga-ebelata ka 3-7 ụbọchị, ebe ọ bụ na ahụ nwatakịrị ahụ bụ ihe mwute na ọgwụ "Prednisolone". Ntụziaka aro ahapụ-ekpokwu ọkụ, gwara na occlusive dressings.

Atụmatụ nke ngwa

Na oge nke ọgwụgwọ na manu-otite ekwesịghị ịbụ ihe karịrị 14 ụbọchị iji gbochie ekwe omume mmetụta si jiri "Prednisolone" ọgwụ ọjọọ. Ntụziaka edepụta na-emeso nanị n'okpuru nlekọta nke ndị ọrụ.

mmetụta

Abụkarị ọgwụ na-ọma na-anabata. Ufodu, karịsịa mgbe ogologo oge eji, nwere ike ime ka itching, ọkụ sensashion, erythema. Na ụfọdụ ndị ọrịa n'akụkụ mmetụta nwere ike gosi ka folliculitis, hypertrichosis, perioral dermatitis, nfụkasị Jeremaya ka ọgwụ mmiri. The n'elu mgbaàmà anaghị achọ ọgwụgwọ na ngwa ngwa wepụrụ na nchupu nke ngwa nke ọgwụ. Ọ ga-eti na ngwa nke ude na otụk akpụkpọ ogologo oge (karịsịa na-emeri nke nnukwu ebe nke anụ) nwere ike iyi mmetụta nke a systemic okike.

Mmekọrịta ndị ọzọ ọgwụ ọjọọ eme ihe

Prednisolone nwere ihe onwunwe iji na-akwalite anticoagulant mmetụta nke anticoagulants. Ọ enwekwu-ekwe omume nke na-agba ọbara mgbe na-ewere salicylates. Ọ na-enwekwu ohere electrolyte metabolism ọrịa na concomitant ochichi nke diuretics. E nwere a na-eto eto ihe ize ndụ nke toxicity mgbe eji gbasara obi glycosides. Mgbada n'usoro hypoglycemic antidiabetic mmetụta na mbelata antibacterial ọrụ nke rifampicin. Ọ bụghị na-atụ aro maka ojiji na njikọ na antacids.

contraindications

Ọgwụgwọ "Prednisolone" ude ntụziaka a ka amachibidoro na:

- hypersensitivity;

- nje, malitere ịrịa, fungal anụ ọnya;

- ụkwara nta, syphilis, anụ etuto ahụ, afọ ime, nkịtị otutu na pink otutu.

ovadozu

Ikpe nke ovadozu na-amaghị.

nchekwa ọnọdụ

Nọ na ndepụta B, na 5-15ºS. Adị ndụ - 2 afọ. Na ngafe nke adị ndụ ghara iji.

ọnọdụ nke ọkọnọ

Prescription.