Salmonella tifimurium - pathogen, nchoputa, ọgwụgwọ

Salmonella bacteria tifimurium mara na nkà mmụta ọgwụ dị ka Salmonella enterica serovar typhimurium. Ọ bụ a gram-adịghị mma, mkpanaka ekara bacteria na flagella (odo odo ntutu-dị ka akụkụ), nke organism Nkea.

Aha ya bụ bacteria - kacha akpata nri nje (salmonellosis) na ụmụ mmadụ. Ọ oria ọ bụ ihe kasị na-anụ ezi, ọkụkọ anụ, àkwá. Anu ulo nwekwara ike na-ebunye ya.

Olee otú Salmonella na-nkewa?

Ya mere, anyị nwere mmasị tifimurium Salmonella - causative gị n'ụlọnga nke ndị dị otú a dị ize ndụ ọrịa dị ka Salmonella. Ụdị Salmonella enterica na-emi esịnede 6 subspecies:

• enterica;
• salamae;
• arizonae;
• diarizonae;
• houtenae;
• indica.

Enterica subspecies enterica agụnye Salmonella esonụ serogroups:

• A (paratyphi A).
• B (derby, typhimurium, agona, Heidelberg).
• C (cholerae suis, Newport, muenchen, virchowinfantis).
• D (Dublin, enteritidis, Rostock, Sendai, typhi).
• E (anatum).

Tifimurium Salmonella (S. typhimurium)

View enterica-atụle ga-pathogenic ụmụ mmadụ na ụmụ anụmanụ nakwa ka nnụnụ, ma, kasị dị ịrịba ama bụ nanị ole na ole n'ime ha ka ụmụ mmadụ. Na ọtụtụ mgbe nke salmonellosis guru nke S. typhimurium.

Ọtụtụ nje Salmonella eguzogide oge a ọgwụ nje, na otú a na-ekesa n'ụwa nile. Ya mere, nosocomial salmonellosis - a oké nsogbu na oge. Na 80% nke ikpe na causative gị n'ụlọnga nke nosocomial (nosocomial) salmonellosis - bụ S. typhimurium.

pathogenicity ihe

Na ihe ize ndụ maka kwuru na-akpata ọrịa pathogenicity esonụ ihe:

• Flagella enye ngwa ngwa ije nke microorganism.
• Capsule nke nje bacteria na-echebe site na phagocytes. Ma n'ihi na nke erughị eru nke phagocytosis emepe sepsis.

• mwakpo penetration mma na-eme ya hassle-free na miri-dina anụ ahụ.
• N'ihi na ezi adhesion (mgbakwunye), na-enye fibrils, pectins, LP-saccharide mgbagwoju, na nje bacteria na-edebe ke idem.
• Exotoxins (ngwaahịa nke ya ọrụ) akpụ afọ ọsịsa na ụdi akpịrị ịkpọ nkụ, ngwa ngwa vaskụla permeability.
• Endotoxin guzo megide ebibi phagocytosis. Ọ lipopolysaccharide mgbagwoju na Nleta igbu egbu. Platelet aggregation na obere capillaries na-eduga ná mbufụt, e DIC. A secretion nke Na na cl ebelata ezigbo muscle na ụba nsia motility.

Olee eguzogide bacteria?

Salmonella tifimurium nwere iguzogide dị iche iche na gburugburu ebe obibi ihe:

1. Ọnwa atọ na ha na-echekwara na ụlọ okpomọkụ metụtara ihe.
2. Afọ anọ echekwara na akọrọ faeces nke ụmụ anụmanụ.
3. Ọnwa ise na - na mmiri, ọkara otu afọ na - na mmiri ara ehi na ngwaahịa na anụ, na eggshells - ruo a ọnwa.
4. Ọnwụ pụtara nanị na 100 Celsius C. The anụ na ngwaahịa nke elu iguzogide okpomọkụ na-abawanye (a pound nke anụ a ga-sie ruo awa abụọ, ma mgbe ahụ na ọ bụ nchebe). Site n'enyemaka nke salting na ise siga na-adịghị egbu Salmonella.
5. Nke a nje nwere ike idi a okpomọkụ ọnụ ka -80 Celsius C.
6. Ọ bụ eguzogide ọgwụ UV ìhè.
7. The disinfectant a chọrọ iji nagide 20 nkeji igbu bacteria.

Outbreaks nke salmonellosis omume hụrụ ke ndaeyo, mgbe mgbe, a chọpụtara na-eto eto ụmụ n'ihi ezughị okè nke ha dịghịzi usoro.

Pathology ebute site ná site alimentary nwekwara kpọtụrụ na kọntaktị-na ezinụlọ. Site n'ụzọ, ọ dị mkpa na-eji àkwá na ntị ka ụdị protein na nkochi ime akwa. Mgbe turbidity, hemorrhage, rere ure ísì, na egg yiri oria. Ọ ga-tụfuo, efere wụsa chlorine aka ka ha na-eme. Ncha na okwu ikpe ndị a na-adịghị aka.

Winter flash, elu enwe na kọntaktị-ulo nnyefe usoro nke nje iguzogide ọgwụ ime ihe na n'ihi na eziokwu na ihe oriri ịnọ ná ntụkwasị obi centralized.

incubation oge

The incubation oge dịruru si isii ka awa asatọ kwa ụbọchị, ma ihe na-mbụ mgbaàmà na-egosi n'ime ụbọchị mbụ ma ọ bụ abụọ mgbe eri a metọrọ emetọ na ngwaahịa.

Bụ imebi mmiri nnu metabolism n'ihi afọ ọsịsa, stool na-aghọ mmiri, frothy, aṅụrụma ruru na elu, na-echetara nke "mmiri na-adọ apịtị" na a ugboro ole nke ruo ugboro iri a n'ụbọchị ahụ, n'ihi a izu ma ọ bụ karịa.

The ọrịa amalite acutely, e ji adịghị ike, lethargy, nwayọọ abdominal mgbu (epigastric na umbilicus). Afo bụ na-egbu mgbu na palpation, audible ụzụ na ọzịza otú ahụ.

Salmonella tifimurium - Laboratory nchọpụta nsogbu

Na nchoputa emetụta ndị na-esonụ parameters:

• ụba erythrocyte sedimentation ọnụego;
• leukocytes na a nnofega-ekpe;

Nje achọpụtara si ndu oke mmiri (feces, ọbara, mmamịrị, ngwa emetụta) na-enyo anyị enyo ngwaahịa bacteriological usoro. The ikpeazụ n'ihi bụ, dị ka a na-achị, na-akwadebe site ise n'ọnwa.

N'elu ọrịa na Salmonella tifimurium, ndị na-esonụ mgbaàmà:

• fever;
• akpata oyi;
• oké afọ ọsịsa;
• vomiting.

ọgwụgwọ

Nke a na ọrịa nwere ike igbu na nwa ọhụrụ, ndị agadi, na na ọrịa na belatara ọgụ. Na nke a dị ize ndụ Salmonella tifimurium.

Ọgwụgwọ bụ na-eji ọgwụ nje na rehydration. Ọzọkwa nye iwu antispasmodics, enzyme preparations, sorbents, antidiarrheals. "Isiokwu №4» egosi na ihe oriri.

Agwọ ga-ẹkenịmde n'okpuru ike ike na-elekọta, na resuscitative jikoro eji na oké ikpe. Of sorbents maka detoxification nke ahụ ọ bụ ihe amamihe na-eji ndị na-esonụ ọgwụ ọjọọ:

• "Enterosgel";
• "Liferana";
• ọrụ carbon;
• "Smecta";
• "Enterodeza".

Na Ugboro persistent vomiting ọ bụ amanyere bụ iwu kpọọ ụgbọ ihe mberede iji gbochie akpịrị ịkpọ nkụ. Onye ọrịa na-emekarị kenyere "Regidron". Mụbara okpomọkụ mbelata antipyretics.

Active megide Salmonella Salmonella enterica ọgwụ nje

Antibacterial mmadụ nọ n'ọrụ megide Salmonella Salmonella enterica, igosi "furazolidone" "Ciprofloxacin", "Rifaximin", "nifuroxazide". Ma ha nwere ike na-nye iwu dibịa, atụtụ onye onunu ogwu na-ewere n'ime akaụntụ ọnọdụ onye ọrịa, na-oria na Salmonella tifimurium.