Antidepressant 'Azafen', ntuziaka maka ojiji, mmetụta

Drug "Azafen" na-ezo aka na ìgwè nke ndị tricyclic antidepressants. Ọ nwere nnukwu ogwuura, anxiolytic na antiaggressive mmetụta. A ọgwụ na ọtụtụ-eji maka ọgwụgwọ nke akpa ume na nke sekọndrị, Ikuku, dị ka:

- endogenous;

- astenodepressiya;

- exogenous;

- aba;

- mkpu;

- ala n'oge somatic ọnọdụ nke a adịghị ala ala uwa.

The n'ọrụ mgwa nke ọgwụ "Azafen" nkọwa na-ezo pipofezine. The usoro nke ihe nke a umi dabeere na mgbochi nke neuronal uptake nke nọrepinefrini na serotonin. Nke a na-eduga onye na-abawanye na ịta nke pipofezine na CNS na dara ya mbà mgbaàmà cropped.

E nwere otu uru n'elu yiri ọgwụ ọjọọ nke antidepressant ọgwụ edinam "Azafen" ntuziaka maka ojiji na-ezo aka na-anọghị nke ya cardiotoxic mmetụta. Ọ na-e kwuru dị ka a na mmetụta dị mma pụtara "Azafen" na affective ọrịa, ebelata somatic, psychic na autonomic ọrịa metụtara na ịda mbà n'obi. High nrụpụta "Azafen" ntụziaka ntuziaka akowa megide asthenia, nsogbu ịda ruru somatic mmadụ psyche. N'oge na ochichi nke ọgwụ na ọrịa kpamkpam nchegbu, nchegbu. Positive Ọnọdụ na ọrịa na anorexia nervosa, nkịtị ụra na ụra kpamkpam n'ụbọchị.

Medicine "Azafen", dabere na ha pharmacokinetic Njirimara nwere ezigbo digestibility, ọ na-ọma etinye obi gị dum site na digestive tract, nwere nnukwu bioavailability (80%), kacha ọbara ịta esịmde ama n'ime 2 awa. Na imeju na-adị site na biotransformation pipofezine na-adịghị ejekwa ozi metabolites-na-egosipụta na akụrụ ya. Full ntọhapụ nke ọgwụ si ahụ emee n'ime 16 awa.

Ọgwụgwọ nke ịda mbà n'obi nke dị iche iche si malite bụ a isi na-egosi maka ojiji nke ọgwụ "Azafen" ntụziaka ntuziaka ezipụta ala, na-edepụta ihe nile ụdị depressioy, gụrụ ọgwụ ọjọọ.

E nwere ọtụtụ contraindications maka inweta antidepressant "Azafen" ntuziaka maka ojiji na-egosi ndị na-esonụ na-ekwu na-adịghị agbanwe agbanwe na ọgwụ ọjọọ na omume:

- arịa ọrịa shuga;

- ekere òkè na Mao inhibitors ;

- myocardial infarction, obi ọdịda, akwara akwara ọrịa;

- hepatic ma ọ bụ gbasara akụrụ odida;

- nje ọrịa, oké;

- ala mgbe oké njọ cerebrovascular mberede (ọrịa strok);

- Pregnancy, lactation.

Ọ ga-eche nche megide ekwe omume omume nke mmetụta n'oge ọgwụgwọ, ha na-kwupụtara dizziness na isi ọwụwa, nfụkasị Jeremaya, vomiting na ọgbụgbọ. N'ụzọ dị mwute, ọ dịghị ihe ọmụma banyere ihe omume na ikpe nke na ọgwụ ovadozu, dị otú ahụ ikpe, ọ na-ewe symptomatic. Ke nsiondi contraindications ga-ahụ kwukwara na otu nsogbu nke "Azafen" na-aba n'anya. Ndị a na-abụọ kpamkpam ibe nanị echiche n'oge ọgwụgwọ a ga-kwụsịrị ịṅụ mmanya na nke imekotaotuugbo n'ikuku nke preparations nwere ethanol.

The "azafen" ahụghị anticholinergic Njirimara, n'ihi ya, anaghị enye ya ọgwụgwọ maka ọrịa na glaucoma. Ọzọkwa-emegide mmanya, e nwere ihe ize ndụ nke imekotaotuugbo ngwa nke ọgwụ na anticoagulants, Antihistamines na niile ọgwụ ọjọọ, CNS depressants. Biko mara na n'otu oge n'ikuku nke "azafen" na antiepileptic ọgwụ na-ebelata ịdị irè nke ikpeazụ.

Tọhapụrụ "Azafen" nditịm dị ka Ntụziaka, karịa adị ndụ bụ 5 afọ, ọ ga-echekwara na tmax 25.