BIMF - New Technology akwụsị ịka nká

The na nkà mmụta sayensị na teknuzu akụkụ

Izi Ezi Ụkpụrụ nke ndu-onye

Medical technology (BIMF)

Mgbe ede nkebi a, nsogbu chere ihu na-ede akwụkwọ: ihe asụsụ na ihe okwu ime ka ngosi. E kpebiri na-akọwa

ọtụtụ nanị, n'ihi BIMF agụnye a dịgasị iche iche nke teknụzụ, na a na nkwupụta ọ bụla "otu ụlọ ọrụ asụsụ" nwere ike ime ka-ezochi ma na nkọwa ndị ọzọ na ọkachamara.

The chọrọ technology BIMF mkpa n'ụzọ bụ isi dị a ọgwụgwọ Usoro n'ihi ọtụtụ narị ụdị achọpụta ọrịa usoro na-adịghị gwọrọ onye ọ bula.

1. Basic ụkpụrụ na ha nnyocha.

Ọ ga-kwuru, na echiche anyị, isi ihe na search maka

a onye nke ụkpụrụ na-esi n'aka ọgwụgwọ. N'ihi na ndị maara ya nwere ike ịgwụ ike, ma ị ka na-echeta otú ọ bụ.

Tupu biakwa obibia nke ọgwụ nje, na mgbe ahụ, mgbe ha na-egosi na ndi mmadu

na-ele anya iji nweta na-eji "kasị mma" pụtara na,

O yiri ihe a ga-emeghe. Onye ọ bụla nọ na-echere ụdị ụfọdụ nke "anwansi bullet"

(Ehrlich). Ọzọkwa, n'elu nchọpụta nke microbial iguzogide

ọgwụ nje, anuri nyere ụzọ nkụda mmụọ. N'otu oge ahụ ndị ọkà mmụta sayensị

mere nke abụọ "imikpu" na herbal na nkà mmụta ọgwụ na eke Efrata

(Mama, shark cartilage, Chaga, ụgwọ herbs) ná mgbalị ịchọta a ebube eke

pụtara. Mmepe nke mkpụrụ ndụ ihe nketa na proteomics chọpụtara nke antioxidants,

nchọpụta nke ọtụtụ biologically-arụ ọrụ bekee, ha na-anabata ya, mmepe nke dị ike chemical pharmacotherapy yiri egosi ụzọ nke impasse n'ọnụ na ihe pharmacology na ọgwụ. N'ezie, ihe ịga nke ọma-enweta na mgbanwe ọgwụgwọ nke ọrịa ụfọdụ, ọ dịghị onye na-agọnahụ. Otú ọ dị, ndị a ịga nke ọma na-ezughị.

Ịchọpụtacha ihe e dere chromosome mmadụ amịghịkwa obere. kpara njikọ ọgwụ ọjọọ na-adịghị agwọ AIDS. Ọbụna 30-35 puku mkpụrụ ndụ ihe nketa nke ụmụ mmadụ na genome enye fọrọ nke nta-adịghị agwụ agwụ nhọrọ na n'ịgwa, ọbụna theoretically-agaghị ekwe omume gbakọọ amụ site n'usoro ọrụ na ha na mmekọrịta nhọrọ.

Ihe kpatara nke odida na ọgwụgwọ nke cancer na ọrịa ndị ọzọ dị na polymorphism (mgbanwe) genomes protein n'ihi mmiri ọgwụ. Ọ dịghị, ọbụna ndị kasị mma, dị ka creators, ọgwụ mgbe n'ezie na-akawanye na 100% na "n'ihi mmiri ọgwụ" nke aru nke a akpan akpan ndidi, n'ihi na nke "ya n'ihi mmiri ọgwụ" na "nke mkpụrụ ndụ ihe nketa", pụrụ iche ya. Olee otú ha si dị iche onye onye? Azịza ya bụ: dị ka ndị mmadụ dị iche iche onye ọ bụla onye ọ bụla ọzọ. E nwere mgbalị iji nwa ebu n'afọ, na-amalite amalite usoro ọgwụgwọ, na n'ikpeazụ sel - "eluigwe na ala" ndu (cell, anụ ahụ) ọgwụ.

Ke ukem, Otú ọ dị, ọ bụ mmepe nke ahaziri na nkà mmụta ọgwụ.

Ọ mere na iberibe. Mee iwebata ọbara ya (autohemotherapy), e guzobere homeopathy (emeso dị ka) (Samuel Hahnemann), na ụkpụrụ e ji mee ihe na nhọrọ nke keonwe

homoeopathic ọgwụ (nditịm n'otu n'otu) na na imewe nke ụfọdụ ụdị ọgwụ (nosodes, renozody) na ihe onwunwe (ọrịa anụ ahụ) nke onye ọrịa. Ịkwadebe onye biologics ihe onwunwe (secretions, ọbara) ọrịa (usoro nke L. Yaschenko, Crimea, Ukraine). Taa, ka ihe atụ, ụfọdụ ndị mba ọzọ Biofirm (ụlọ ọrụ «Antigenics Corporation») na-mere si a kansa akpụ anụ ahụ nke ọrịa maka otu ọrịa - mgbochi cancer ogwu ihe maka nzube nke omume (immunotherapy) megide ha cancer.

N'ihi ya, anyị nwere ike ịmata ihe dị iche isi ihe abụọ na ọnọdụ na-mgbanwe ọgwụgwọ.

Mbụ.

Medicine na-agbalị-esi na-akpata (etiology), ma ọ bụ na mmepe nke ọrịa usoro (pathogenesis). Ntem, n'ihi na ihe atụ, ọgwụ nje, ọ na-atụle isi ịdaba mere: ibibi pathogens ke idem, e.g., na-efe efe. Antihypertensive ọgwụ ọjọọ na-emekarị-eme ihe dị iche iche usoro (pathogenesis) nke ọbara mgbali.

Rịba ama Otú ọ dị, karịsịa himiolecheniya. Ọbụna adịghị ala ala ọrịa, ọtụtụ mgbe, ọgwụ na-eji "mberede" enyemaka. Ntụgharị eji ọgwụ ọjọọ eme ihe ga-ekiri na mma - ụbọchị.

Drugs eme afọ na ọnwa, ọ dịghị. Ọ bụ ezie na, dị ka ha na-ekwu, ihe niile

adịghị ala ala ọrịa na-kpatara ogbenye ndụ nhọrọ, ya bụ,

ogologo oge na nnukwu ọrịa na nhụjuanya - a okwu nke ohere.

Na ọgwụgwọ nke ala ala ọrịa anwa ogologo ọgwụ eme ihe, dị ka iji ha na depositing ma ọ bụ itinye iche iche "nwere ọgụgụ isi lipid nanocontainers" ma ọ bụ ruo ogologo oge forms (e.g., Bitsillin). Ke adianade do, ọtụtụ mgbe adịghị ala ala ọrịa ọgwụ na-akwụsị na-arụ ọrụ, na ha nwere mgbe nile ịgbanwe: ịgbanwe "onwu" nke aru nke onye ọrịa ma ọ bụ mkpụrụ ndụ ihe nketa, nke antigenic mejupụtara nke nje ahụ. Ma ọ bụ, na mbụ ọgwụ anaghi ruru ka a mkpụrụ ndụ ihe nketa ma ọ bụ Biochemical polymorphism (iche iche) nke organism nke ọrịa na pathogens.

Nke ahụ bụ, na a na obibia nke ọgwụgwọ, ọgwụ ndị na-eji kpọọ ma ọ bụ na-emetụta naanị a òkè nke enweghị nchịkwa usoro, na site ha ọdịdị ha kpamkpam ọbịa aka ahu, na ebe ọ bụ na-emepụta site chemical ụzọ.

The abụọ na-emekarị.

Ọ bụ doro anya na anya onye, ma dabere na iju kwuru. Na homeopathy, na kacha mma, ọ na-akọwa "ụdị" onye ọrịa, a mmachi ndepụta homeopathic ịgba akwụkwọ. Autohemotherapy (ọgwụgwọ nke ọbara ya) emeghị-enye ezi mmetụta: bụghị naanị na ọbara maka ọgwụgwọ na bụ kpamkpam doro anya, n'ihi na ihe atụ, ndị feasibility nke na-ewebata a ọrịa ọbara sepsis. Na na ọ bụ n'ezie onye na-kwadoro anya feasibility nke n'ichepụta na ngwa nke ndu ngwaahịa mere si ha onwe ha, gbanwetụrụ ọrịa, ie pathologically gbanwere anụ ahụ. Na ngụkọta oge, mgbe a na-eme, Otú ọ dị, na ahụ ji alụso ọrịa omume. Ma nwere ike ịza a dị ike counter-agha nke dịghịzi usoro nke ọma, na-ama, ike agwụ site na ọrịa, dị ka ọrịa cancer?

Ahụhụ nrụpụta ọrụ nke influenza vaccines, na-apụghị ime nke inweta ọgwụ mgbochi megide AIDS na cancer jikọtara ma mkpụrụ ndụ ihe nketa mgbanwe nke pathogens, na site na mkpụrụ ndụ ihe nketa akwusighi nke organism onye ọrịa mkpụrụ ndụ (heterogeneity). Olee otú "catch" ndị mgbanwe enweghị nchịkwa ọnọdụ na-agbanwe agbanwe pathogenesis, na-agbanwe mkpụrụ ndụ ihe nketa nke ọrịa usoro na-agbanwe ngwa ngwa na mkpụrụ ndụ ihe nketa nke enweghị nchịkwa microorganisms (na-akpọ "pathomorphosis" mkpụrụ ndụ na anụ ahụ na cancer, HIV, heterogeneity nke AIDS)? Otú enwetaghị ihe a na-agbanwe n'ike n'ike? Dị ka "na friji" iche iche nke ọgwụ na-emeso nnọọ ngwa ngwa na-agbanwe agbanwe-enweghị nchịkwa na usoro ma ọ bụ ihe na-nnọọ ngwa ngwa genetically gbanwetụrụ?

Ọzọkwa, dị ka ọ na-e hụrụ: chromosome mmadụ nwere niile mara genomes, gụnyere pathogenic mmadụ nje (pathogens). (Na nke a "ikpe" evolushọn). Olee otú iji kwụsị ọgba aghara nke ha onwe ha DNA na cancer na AIDS? Gịnị ma ọ bụrụ na na mmalite nke DNA nke ọrịa naanị, na mgbe ahụ, ọ bụ dị iche iche? Bipụta odida nke mmepụta nke ọgwụ mgbochi maka cancer na AIDS. Olee otú ike a ndu agha (biobronyu) nke karịsịa ize ndụ na-efe efe?

E nwere ihe nke atọ, a ugboro ugboro na-emekarị - biologics, biotech - ọgwụgwọ ọbara, interferons, insulins, pirogenal (enwetara site na ịba), prodigiozan, bifidus, lacto-bacterins, etc .. All ndị a allotropic, nke na-enwetara site na mba ọzọ mkpụrụ ndụ na (Micro) ntule.

Ịgba ọgwụ mgbochi ọrịa ga-obibi ebe a, dị ka ọ bụ na-emekarị, na ma e wezụga ndị mgbochi.

Mgbe na-eji dochie anya ọgwụ (ọbara nọ n'ọnọdụ, protein preparations ...), isi nchegbu ndị dọkịta bụ ọgwụ iji n'ụzọ zuru okè ma n'ụzọ ziri ezi "na akara" na n'ihi mmiri ọgwụ nke ahụ: ga-enye ọ bụla mmetụta, ma ga-ọzọ na gwọrọ. Ya mere, mgbe agbara, iji dị iche iche n'omume maka "ndakọrịta" na onye ọrịa ahụ. nnọchi ọgwụ ọgwụ ọjọọ na-agaghị biologically mmadu.

Ihe mgbaru ọsọ nke ọgwụgwọ maka ọrịa cancer na AIDS - igbu genetically gbanwetụrụ mkpụrụ ndụ, na mgbe ahụ ka ndị uto nke ọdọ mmiri (nke puru na ha na ndị ezinụlọ) nke ha nkịtị mkpụrụ ndụ.

Taa mgbalị unit normalisation Jenetik nwere (autosomal) maka mmezi nzube arụpụtara nke ọrịa mkpụrụ ndụ na n'etiti manipulations na vitrum (-tube technology) eji nkà mgbanwe mkpụrụ ndụ usoro (nyefe na site n'usoro shuffling) iji plasmids, nje, "Vektọ", wdg Ndị dị otú ahụ ihe ịga nke ọma dị obi umeala, na ihe isi ike na nsogbu nke mkpụrụ ndụ ihe nketa mara na egwu.

Abụọ okwu banyere ife mkpụrụ ndụ ihe nketa. Na echiche anyị, e nwere nsogbu na-amụba na-aperiodic mgbaàmà si nkịtị DNA, n'ihi na nke E.Shredinger - DNA aperiodic. N'ihi ya, anya, ka anyị ihe ọmụma, ọ bụghị a guzosie ike generator ike nke na-amụba aperiodic n'ókè gafee n'obosara-akpa iche iche. Wave ọgwụ nditịm biologically azụmahịa ugbo ala, ọ na-"nkezi".

Nke ahụ bụ otú anya, na a Roundabout ụzọ nkà mmụta ọgwụ na pharmacology, iji, dị ka a na-achị, mba ọzọ bekee, ntule, Micro-ntule na ọbịa mkpụrụ ndụ ihe nketa - agbalị normalize na mkpụrụ ndụ ihe nketa na n'ihi mmiri ọgwụ ahụ nke a akpan akpan onye ọrịa, na na - na-agwọ ya.

Na ọgwụgwọ nke sel eji onye ọzọ bụ ma ọ bụ gị onwe gị na mkpụrụ ndụ. Isi nsogbu na ọgwụgwọ nke sel, na echiche anyị, bụ distortion nke ọgwụgwọ mmetụta n'ihi na undecidability nke ndị dị otú ahụ oge: 1. ọ dịghị ekwe omume mgbe nile na-emepụta a ezubere iche nnyefe nke sel n'ime chọrọ ngwa, anụ ahụ ma ọ bụ na-elekwasị anya; 2. ọ dịghị ekwe omume na-enye onye ọ bụla nke ha somatic cell a azuokokoosisi cell; 3. banyere ọbara sel na-ekesa na-enweghị usoro ofụri idem; 4. ọ dịghị nkwa nke na-sel nri ebe; 5. anaghị Eburu amuma n'ihi nke ọgwụgwọ n'ihi na random nkesa nke sel. 6. The ọgwụgwọ mmetụta nke sel a hụrụ naanị na ihe dị nso n'ubi n'ebe ya na ọnọdụ; 7. systemic mmetụta na aru dum si mmetụta nke azuokokoosisi sel na-adịghị karịsịa gosiri n'ihi ka obodo edinam nke azuokokoosisi sel na quantitative ndiiche n'ihi: ọnụ ọgụgụ nke somatic (anụ ahụ) na ọnụ ọgụgụ nke mkpụrụ ndụ ndinọ azuokokoosisi mkpụrụ ndụ.

Nso nso, anyị na-ekwukwa na na-emekarị n'ebe ndị dị warara selectivity nke edinam kere ọgwụ ọjọọ - ha egosipụta ọtụtụ ihe - ka ha edinam na na ọtụtụ iche.

N'ọnọdụ nile, na-emeso ma na-agwọ a onye na-agba mbọ iji ndị dị otú ahụ na mmetụta na ọgwụ, nke, n'ikpeazụ, normalized ya (ndidi) niile n'otu n'otu metabolism (homeostasis) na / ma ọ bụ niile nke ya mkpụrụ ndụ ihe nketa, nke pụtara a laghachi a steeti ahụ ike.

N'ihi ya, mgbanwe ọgwụgwọ (pharmacological) obibia nke n'inwe dum organism (ndụ dum usoro) na ya niile usoro, gụnyere mkpụrụ ndụ ihe nketa, - bụghị e meghere na ya ka e ji mee ihe.

Ndien ke akpatre, ndị ikpeazụ. Onye eziokwu nke n'amaghi (n'amaghi) olileanya na-adịghị na-agwọ ọrịa na ogbo 4 cancer na-atụ aro otu: e nwere a laghachi nkịtị onye na niile nzukọ etoju: molekụla, subcellular, cellular, anụ ahụ, ngwa, wdg Nke ahụ bụ, a laghachi nkịtị, "iji" iwu - bụ ihe mgbaru ọsọ kasịnụ nke na-agwọ ọrịa na ọgwụgwọ. Ya mere, gịnị na-eji maka ọgwụgwọ nke "nkịtị"?

Ọ na-aghọta na mgbake na-alaghachi ahụ nkịtị, na ahụ ike pụrụ na a ga-eme kpọmkwem iji gị otu nwa afọ ndu, Biochemical, mkpụrụ ndụ ihe nketa ọmụma nke ha onwe ha ike anụ ahụ (somatic) mkpụrụ ndụ na-agba zuru ndu ọmụma iji totipotent mkpụrụ ndụ.

Ọ dịghị mkpa ka na-a dibịa mara na ọ bụrụ na a onye a mụrụ na biri ndụ ya afọ na-enweghị anya mgbaàmà na nsogbu na pụrụ ịbụ indicative nke ya mkpụrụ ndụ ihe nketa ọrịa, ọ bụ na ndabara, nke yiri ka mmadụ mkpụrụ ndụ ihe nketa bụ na mbụ nkịtị. Ya mere, i nwere ike iji ya na BIMF gụrụ mkpụrụ ndụ maka nzube nke na-agwọ ọrịa na Iweghachi ahụ ike nke onye.

Otú ọ dị, maka nchoputa nke "nkịtị" somatic cell kwuo nwere ike ji mee ka sequencing (ịgụ) genome (oké ọnụ usoro, iru ala, ntugheriukwu iji na nlekota genome) ma ọ bụ "genome nchọpụta nsogbu na nrịbama nkịtị pathologies" - histone edozi (dị ma ọ bụghị obere ezi usoro nke adabere na ala nke genome, karịsịa - ya ike mmepe nke Russian -. Paponov ede Vladimir D. et al, Medical Jenetik Research center ebule, Moscow) ..

Goals - ịzụlite ụkpụrụ na nkà mmụta sayensị na ntọala nke ahaziri na nkà mmụta ọgwụ na ọgwụgwọ dabeere na ndị ọzọ karịa chemical pharmacotherapy ụkpụrụ (ụzọ) - e setịpụrụ dị ka mkpa na mkpa ngalaba nke Russian Technological Development Programme maka oge 2007 - 2011, edise ke Russian Government. Nzube ndị a na-enweta site na anyị.

Ka ụbọchị, maka nzube nke oma (site creators nke uche) na na kasị mma ọgwụgwọ - ụwa na-eduga na-emepụta ọgwụ na biotechnology ọgwụ eji karịa iru nke "individualization" nke nhọrọ na mmepụta nke ọgwụ.

N'ezie, e nwere a ọka nke eziokwu ke eziokwu na na imewe nke ọgwụ Nsukka, depụtara n'okpuru ebe a, n'ihi "eluigwe na ala" keonwe, individualization, biotechnological usoro na-tutu amama antigenic otu, kpọmkwem Njirimara nke ọgwụ ọjọọ nke ndu bekee na-eme ka ndị a otu ihe ahụ ọgwụ ọjọọ eme ihe, si otú tọgharịa (boo) ha antigenicity , allogeneic (ndu foreignness). N'ihi ya, ọ bụ mmasị na "universality" itinye "niile" dị otú ahụ ọgwụ ọjọọ.

Nke a na obibia imewe nke ọgwụgwọ dị nnọọ ka ojiji nke sel na biotherapy, na "zeroed" n'echiche nke ha heterogeneity (mba ọzọ), na otú - "eluigwe na ala" ntuziaka maka ojiji.

N'ihi ya, German mgbagwoju preparations «n'ikiri ụkwụ» na / ma ọ bụ Italian «OTI» (Officine Terapie Innovative) nwere (ma ọ bụ bu n'obi iji)

homeo (yiri) + + Organotropona nnọchi (nnọchi) Efrata.

(Lee., Karị, n'ihi na ihe atụ, katalọgụ nke preparations nke German ụlọ ọrụ "Biologishe Haylmittel n'ikiri ụkwụ GmbH" General Medicine 2011-2012, JSC "Alfa leporis», 2011. www.heel.com) (Ndenye Reference "Compendium" nke pharmaceuticals nchegbu OTI www. otiomeopatici.com).

Na, tutu ke akpatre, ọgwụ nwere pharmacologically-arụ ọrụ bekee - organic-na anụ ahụ-kpọmkwem cell bioregulators (peptides, wdg) Nke dị iche iche na akụkụ na sel (obi, ụbụrụ, pineal gland, obere eriri afọ, nnukwu eriri afọ, erythrocytes, imeju, ovaries, Lymph, mammary gland, muscle mkpụrụ ndụ, akụrụ, ụmị ọkpụkpụ, pancreas, pituitary, akpa ume na bronchus, afo, prostate, splin, ntorobịa thymus, thyroid, akpanwa, testicles, nwa ebu n'afọ na nwa anụ ahụ), agbala taa «vitOrgan» ụlọ ọrụ ( Germany).

Àjà ndị a ọgwụ ọjọọ, «vitOrgan» ekwuwàpụta dị ukwuu dị ka o kwere omume kpọmkwem individualization, keonwe nke ọgwụ ikpughe. Ọgwụ ndị a na-mere si akwa (ma) anụmanụ zụlitere na ọcha gburugburu ebe obibi na Cleaner faili ntanetịime.

Taa, echiche uche nke ndị Russia n'ụzọ doro anya gbanwere kwupụta naturalization ka a nri na nkà mmụta ọgwụ. All bụ obere yiri ka nọgide na-maka oriri na ojiji nke Chemical Pharmacology nke ọgwụ ọjọọ. People n'af ihu nke uwa, na-ahọrọ eke ọgwụ na nri, dị ka megide na ya synthesized na-abụghị onye.

Ịtụle niile n'elu, ọ ga-kwuru, sị obibia nke zuru ụwa ọnụ na-emepụta ọgwụ na biotechnology n'ihi keonwe, individualization nke ndu ọgwụ onwe ha na individualization (bio) teknụzụ maka ha mmepụta.

A obere oge, na "ga-eru na niile" ihe ọgwụ ga-enweta ma na-emeso ha site ndu-onye ahụ ike teknụzụ (BIMF).

N'ihi na onye ahụ ga-anọgide na a mkpa nke a technology?

Ụzọ nke eji

bio-ọgwụ onye teknụzụ (BIMF)

maka ọgwụgwọ ma ọ bụ onye nke ọkọlọtọ na-emepụta ọgwụ ọgwụ ọjọọ,

enweghị ngosi nke etu esi.

amịpụtara ọtụtụ ike ndụ nwere cell nuclei, maka nzube nke na-agwọ ndị ozu ọrịa, n'ahụ onye ọrịa ahụ.

Ịza ajụjụ.

Mmịpụta si mkpụrụ ndụ nke organism nwere ike ebu invasive (site na mbepụ, mgbapu) na noninvasive (n'ejighị ọbara) usoro (atụ, iko ma ọ bụ akara na cell akpụcha). Na ọ bụla na-arịa ọrịa ahụ, ma ọ bụrụ na ọ bụghị ihe ketara mkpụrụ ndụ ihe nketa ọrịa na 100% mmeri, mkpụrụ ndụ nile, bụ mgbe niile dị ka a ike, na ike mkpụrụ ndụ ihe nketa somatic (aru) mkpụrụ ndụ. Ọ bụrụ na ọ dị mkpa, amịpụtara si ọ bụla mkpụrụ ndụ nke organism, gụnyere sighting e si anụ ahụ ma ọ bụ akụkụ, ndị dị otú ahụ dị ka arụmọrụ ohere. Maka nzube nke BIMF amịpụtara na-eji nkịtị mkpụrụ ndụ nwere a ntọala (eukaryotic) na gbaa a diploid (full, abụọ) set of chromosomes, ya bụ, zuru genome - nwere totipotent mkpụrụ ndụ. Dị ka e kwuru site n'oge a mkpụrụ ndụ ihe nketa, ọ bụ totipotent mkpụrụ ndụ na-ebu zuru ọmụma (gụnyere mkpụrụ ndụ ihe nketa) nke ahụ site na nke ha na-jide: site nwere totipotent mkpụrụ ndụ ike nke na-emepe emepe a dum organism (Dolly atụrụ).

Help.

N'ezie - anụ ahụ (somatic) mkpụrụ ndụ, anụ ahụ nke, ọ bụghị taa na-akpọ totipotent, na differentiated. A totipotent akpọ naanị ẹmbrayo sel. Ọbụna rata pluripotent azuokokoosisi cell (IPS) na-akpọ pluripotent ...

Dị oké mkpa bụ eziokwu na diploid somatic (aru) mkpụrụ ndụ na-ebu zuru nwere totipotency.

Na amịpụtara mkpụrụ ndụ na a n'ụzọ pụrụ iche (technology) na-mma na omume dị ka a N'ihi nke n'anwụ, dịpụrụ adịpụ na wepụrụ niile dị na nke ọ bụla n'ime ndị a na mkpụrụ ndụ, ma ọ bụ niile ndu ọmụma ndị a na mkpụrụ ndụ. Na nke a, ma ọ bụrụ na ọ dị mkpa, na cell ụdị (anụ ahụ ngwa) mkpụrụ ndụ nwere ike ịnara ma ọ bụ neutralized ma ọ bụ echekwara, ma ọ bụ gbanwetụrụ. Mgbe ahụ dum cellular ọdịnaya, ma ọ bụ ndu ọmụma banyere cellular ọdịnaya amụba (ba uba) a n'ụzọ pụrụ iche, na a pụrụ iche na-ajụ (ụgbọelu).

Ịza ajụjụ.

Nke a bụ isi milestone na BIMF. Mgbe n'imeso mkpụrụ ndụ na a ogbo na-eji dị ka-ahụkarị na mara usoro na technology nakwa dị ka ihe pụrụ iche (ike), n'otu a otu na nkà na ụzụ okirikiri. Mkpụrụ ndụ na / ma ọ bụ ha ọdịnaya na-gụrụ, n'usoro, a chemical Solo-jel technology, micromanipulation, anọ ma ọ bụ na-eto eto na laabu cell omenala agụụ mmetụta, cryotherapy, mmetụta, na iji ahaziri ihe na Micro-nanolayers na pores ... ụfọdụ etinyere ha na ijikọta niile nkebi nke technology.

A pụrụ iche bụrụ na ụdị imepụtaghachi ndu ọmụma taa bụ, ihe atụ, PCR technology (Polymerase Chain Mmeghachi omume), kọwara theoretically na 1971 na ihe amụma na 1983.

Na PCR, dị ka a maara, pụtara multiplexing (multiplication, multiplication, ugboro ugboro Iṅomi, amplification) nke ndu ọmụma n'ụdị DNA (ya iberibe).

The ụgbọelu nwere ọtụtụ na ya ndu ihe onwunwe, bughi ihe ọmụma banyere a ike cell, nke na-- na cellular ahụ ike - na ẹkenam n'ime ahu nke onye-enwe ndidi, nke ya onwe ya ike somatic mkpụrụ ndụ na-na mbụ napụrụ.

Ịza ajụjụ.

A na-ajụ nwere a biologically-onye ozi, mgbe ndinọ ka a na-ekwe nkwa esịmde na penetrates n'ime niile somatic mkpụrụ ndụ. A ga-esi otú a gụrụ otu ugboro niile somatic mkpụrụ ndụ. Cheta: ngafe biologically-onwe na nkwado nye site na ya multiplication (multiplication). Ka ihe atụ, ndu ọmụma na-amịpụtara si mkpụrụ ndụ 10 nwere ike multiplexed ọtụtụ nde mmadụ ma ọ bụ ọtụtụ ijeri. N'ihi ya, ihe na ozi a ga-webatara site n'oru nke ọtụtụ nde mmadụ na ọtụtụ ijeri ndị a na mkpụrụ ndụ!

N'ihi ya, ọrịa ahụ na-enweta na ngafe nke ya (nditịm biologically onye!) Ozi banyere norm nke ahụ ike. Ngafe ike ọmụma na ahụ gị na-na-ekwe nkwa na-aghọ (ndetu) azụ-enweghị nchịkwa na ọmụma na Filiks, ie - apụta ma na-agwọ ọrịa. Ngafe nke ndu ahụ ike ọmụma ga-amụba n'ike n'ike n'elu nkịtị mgbe ụfọdụ ka ahụ na-eguzogide ọ bụla mmetụta.

Uru na atụmatụ BIMF

(Bio-onye ọgwụ technology).

BIMF bụ onye na-agwakọta ikekwe nile di iche iche nke taa elu teknụzụ - nano-, bio-, cryogenic, agụụ, cell, Sol-jel, pharma, ọla kọpa, mikroinstrumentalnye - dị nnọọ mkpa ka ngwa nke ndụ usoro na n'otu oge ahụ nwere a n'otu - na "ise mmewere". Eji na plasma technology, elu-okpomọkụ agụụ ngwá maka nhazi na n'ichepụta ngwá egwú na laabu glassware.

The technology-enye gị ohere naghachi (iji gwọọ) dị ka dum, na ya iche iche akụkụ na anụ ahụ - na nke kwesịrị ekwesị mgbanwe usoro technology.

Nkọwa.

BIMF usoro nwere ike ịga nke ọma ịzụlite ẹdude teknụzụ taa na-eto eto autologous akụkụ na anụ ahụ.

BIMF usoro na-eme ka o kwe omume na-eji ya maka nzube nke ịkwụsị ma ọ bụ revertirovaniya (laa azu) afọ metụtara mgbanwe ozugbo dum organism.

BIMF usoro na-enye ohere n'otu n'otu hazie ọkọlọtọ ọgwụ preparations, "ukpụhọde, na-agbanwe ha mebere atumatu" n'okpuru n'ihi mmiri ọgwụ nke organism ma ọ bụ ndidi mkpụrụ ndụ na anụ ahụ, ebe ndị gbasara ohere conformation nke ọgwụ ụmụ irighiri agaghị agbanwe ya ahụrụ anya usoro. (Adịghị emerụ ikike nke ọgwụ na-emepụta). Gbanwetụrụ site n'ụzọ zuru ezu BIMF ọgwụ nkwadebe adabara onye ọrịa ahụ, ya mere ga-jirichaa ya ọgwụgwọ mmetụta na n'otu oge n'ibelata ha oghom ma ọ bụ na-egbu egbu na mmetụta, ịbụ konformirovannym n'otu n'otu.

Nkọwa.

BIMF Nke a were ga-abụ "ọlaedo" n'etiti - ikwere n'etiti ọgwụ ọjọọ na-emepụta - farmfirm (farmbiznesa) na otu aka, na BIMF - kpere onye "bezhimicheskoy" ọgwụ technology, na aka nke ọzọ, nke a ọgwụ mere si igredientov nke organism. Mgbe niile, ndị technology nnoo eliminates BIMF iji na ọgwụgwọ nke chemical pharmacology, ie-eme ka ọ na-enweghị isi na-emepụta ọgwụ chemical ụlọ ọrụ dị ka ndị dị otú ahụ. Otú ọ dị, ndị dị otú ahụ a obi ike na nkwupụta, na i nwere ike ime iji ọkọlọtọ BIMF na chemical preparations na Nchikota, aka na ọgwụgwọ mmetụta nke nkwonkwo.

Ọ maara na ihe atụ, na-ewu ewu vitamin C (ascorbic acid), ndị nwere otu ahụrụ anya usoro dị ka molekul nwere 28 gbasara ohere configurations (isomers), nanị otu onye nke nwere a ndu ọrụ n'ime ụmụ mmadụ. Gbasara ohere nghazi bụ mgbe a isi ihe mere adịghị ike nke ndị ọgwụ ọjọọ eme ihe. Na dị ka a na nkwenye: ọ bụ a mgbanwe nke gbasara ohere conformation nke protein na-akpata prion ọrịa na (spongiform encephalopathy = = ọrịa ehi ara, scrapie , etc ..), Ònye taa amaghị - esi na-emeso. (Prions - protein umu).

All mere ka ụbọchị pharmaceuticals nwere a gbasara ohere Ọdịdị, ya mere ike nke spatially konformirovatsya.

Maka usoro BIMF bụghị mkpa pharmaceuticals isi gbasara ohere Ọdịdị: ọ ga-konformirovana na dị na iche nke ihe banyere mmiri ọgwụ nke organism (ma ọ bụ mkpụrụ ndụ) nke a ndidi.

BIMF usoro pụrụ iche na ya, mmejuputa iwu leghaara ndị na-akpata (etiology) nke ọrịa na usoro nke ọrịa (pathogenesis), dị ka ha bụ nanị na-adịghị mkpa (ma e wezụga n'ihi ketara ọrịa).

The usoro na-eme ka o kwe omume iji gwọọ prion na o doro anya na ụfọdụ ketara mkpụrụ ndụ ihe nketa ka ọrịa, na nke ikpeazụ ikpe - ma ọ bụrụ na ndị nne na nna dị ndụ ma na / ma ọ bụ probands (ụmụnna ọ) nke a ndidi.

Na usoro nke imepụtaghachi BIMF ga-akwagide ndu ozi nile usoro na on dum ọdịnaya nke cell - mara na-amaghị ka ụbọchị.

BIMF na-enye ohere itinye oge dị iche ọmụma si na otu ọrịa ọma gwọọ, n'agbanyeghị mkpụrụ ndụ ihe nketa mgbanwe nke pathogens ma ọ bụ mkpụrụ ndụ (anụ ahụ) nke organism.

BIMF-enye gị ohere na-arụ ọrụ na mkpụrụ ndụ 'nsogbu' ngwa na anụ ahụ: ma iche iche na ọnụ ozugbo - dị ka ọ na-eme n'ahụ. The usoro na-eme ka o kwe omume na-eleghara, ya bụ, ọ bụghị na-emetụ ndị na-akpọ nsogbu nke Hayflick (ịmachi ọnụ ọgụgụ nke mitosis 50 maka somatic sel, telomeres nsogbu telomerase), dị ka iji nweta ihe ndị ha chọrọ n'ihi na usoro technology nwere ike ji mee BIMF mkpụrụ ndụ nanị "na-eto eto" ọgbọ - ie mkpụrụ ndụ si "mbụ, n'oge" mitoses.

Na BIMF anyị ji: Genetic Engineering (ụzọ nke shuffling na site n'usoro nyefe), cloning ntule, radieshon na ndị ọzọ environmentally-emerụ ma ọ bụ unyi technology. Ndu umu anwuru n'ime gburugburu ebe obibi n'oge BIMF tụnyere naanị anwuru si handwashing na ncha ma ọ bụ ozu.

Ụzọ nke eji

bio-ọgwụ onye teknụzụ (BIMF)

maka nzube nke ịkwụsị merela agadi (mgbochi ịka nká), na-enweghị igosipụta etu esi.

Nkenke technology bụ nke a: site a na-eto eto mkpụrụ ndụ na-amịpụtara. Ọ bụrụ na ndị agadi organism, ya na mkpụrụ ndụ, mgbe mmanụ, enịm n'ime a laabu cell omenala vitro ebe ha ba uba na rejuvenated. Site ma ọ bụ ewepụtara dum na-eto eto na mkpụrụ ndụ amịpụtara ndu ọmụma nke na-agafere na-ajụ ebe ọ ba uba (amụba). Mgbe ahụ, ụgbọelu nke a "na-eto eto" ndu ọmụma na ẹkenam ke ngafe na ahu na penetrates n'ime ya niile mkpụrụ ndụ. N'ihi ya, ahụ na-enweta karịa nke ya onwe ya ndu "nwa" ọmụma, nke ga-eduga ọ dịkarịa ala na-akwụsị agadi ma ọ bụ rejuvenation. (Ese ọzọ nkọwa zuru ezu.)

N'ihi ya, mgbe na-eji na dum organism BIMF enweta nditịm onye (ahaziri, onye):

1. agwọ;

2. The mgbochi ịka nká (rejuvenation) ma ọ bụ gwara ndu afọ;

3. onye ọkọlọtọ ahịa ọgwụ na-emepụta ọgwụ ịgba akwụkwọ;

4. biobronya: onye ngụkọta mgbochi (amplification n'oge niile na-echebe ndu Njirimara nke organism).

Na ngwa nke teknụzụ ndị a niile na otu onye, anyị na-enweta otu onye ahụ, ma ọ bụ na a ụzọ ọhụrụ! N'otu oge ahụ, ọ na-anọgide na ya, ya bụ - ga-anọgide na otu onye, otu àgwà, iche.

N'otu aka ahụ, BIMF oru ngo nwere ike kere n'ime otu sub-4, bụ nke a ga-edo ndabere - BIMF. Na, n'ezie, niile anọ ebe ike rụrụ na a otu center BIMF.

Method nke Iji (Method)

bio-ọgwụ onye teknụzụ (BIMF)

maka nzube nke ịkwụsị merela agadi (mgbochi ịka nká), na-enweghị igosipụta etu esi.

Nkenke technology bụ nke a: site a na-eto eto mkpụrụ ndụ na-amịpụtara. Ọ bụrụ na ndị agadi organism, ya na mkpụrụ ndụ, mgbe mmanụ, enịm n'ime a laabu cell omenala vitro ebe ha ba uba na rejuvenated. Site ma ọ bụ ewepụtara dum na-eto eto na mkpụrụ ndụ amịpụtara ndu ọmụma nke na-agafere na-ajụ ebe ọ ba uba (amụba). Mgbe ahụ, ụgbọelu nke a "na-eto eto" ndu ọmụma na ẹkenam ke ngafe na agadi (ochie), na ahu na penetrates n'ime ya niile mkpụrụ ndụ. N'ihi ya, ahụ na-enweta karịa nke ya onwe ya ndu "nwa" ọmụma, nke ga-eduga ọ dịkarịa ala na-akwụsị agadi ma ọ bụ rejuvenation.

Ịza ajụjụ.

Mmịpụta si mkpụrụ ndụ nke organism nwere ike ebu invasive (site na mbepụ, mgbapu) na noninvasive (n'ejighị ọbara) usoro (atụ, iko ma ọ bụ akara na cell akpụcha). Lessons-eto eto na mkpụrụ ndụ ma ọ bụ ewepụtara na-eto eto na mkpụrụ ndụ nwere ike enịm maka safekeeping na Cryobank ruo mgbe ha na-eji. cryo-nchekwa mkpụrụ ndụ na-enye ha na nchekwa umu, ya bụ, fọrọ nke nta - agelessness. Ọ bụrụ na ọ dị mkpa, aru-Ewepụtara ọ bụla mkpụrụ ndụ, gụnyere sighting e si anụ ahụ ma ọ bụ akụkụ, ndị dị otú ahụ dị ka ezigbo oge ohere ma ọ dị mkpa na a ụdi sighting ma ọ bụ mpaghara "rejuvenate" akụkụ ma ọ bụ anụ ahụ. Maka nzube nke BIMF amịpụtara na-eji nkịtị mkpụrụ ndụ nwere a ntọala (eukaryotic) na gbaa a diploid (full, abụọ) set of chromosomes, ya bụ, zuru genome - totipotent mkpụrụ ndụ. Dị ka e kwuru site n'oge a mkpụrụ ndụ ihe nketa, ọ bụ totipotent mkpụrụ ndụ na-ebu zuru ọmụma (gụnyere mkpụrụ ndụ ihe nketa) nke ahụ site na nke ha na-jide: si totipotent mkpụrụ ndụ na-enwe ike ịzụlite a dum organism. Nke ahụ bụ, ihe niile ndu mkpa nke organism dị ka a dum, dị ka a dị ndụ usoro na-nyere ma ọ bụ nwere ike na-nyere potencies (ike) totipotent mkpụrụ ndụ. Ọ bụ ya mere nwere totipotent mkpụrụ ndụ na-eji na BIMF.

Na-eto eto ma ọ bụ rejuvenated mkpụrụ ndụ na a n'ụzọ pụrụ iche (technology) na-mma na omume dị ka a N'ihi nke n'anwụ, dịpụrụ adịpụ na wepụrụ niile dị na nke ọ bụla n'ime ndị a na mkpụrụ ndụ, ma ọ bụ niile ndu ọmụma ndị a na mkpụrụ ndụ. Na nke a, ma ọ bụrụ na ọ dị mkpa, na cell ụdị (anụ ahụ ngwa) mkpụrụ ndụ nwere ike ịnara ma ọ bụ neutralized ma ọ bụ echekwara, ma ọ bụ gbanwetụrụ. Mgbe ahụ dum cellular ọdịnaya, ma ọ bụ ndu ọmụma banyere cellular ọdịnaya amụba (ba uba) a n'ụzọ pụrụ iche, na a pụrụ iche na-ajụ (ụgbọelu).

Ịza ajụjụ.

Nke a bụ isi milestone na BIMF. Mgbe n'imeso mkpụrụ ndụ na a ogbo na-eji dị ka-ahụkarị na mara usoro na technology nakwa dị ka ihe pụrụ iche (ike), n'otu a otu na nkà na ụzụ okirikiri. Mkpụrụ ndụ na / ma ọ bụ ha ọdịnaya na-gụrụ, n'usoro, a chemical Solo-jel technology, micromanipulation, anọ ma ọ bụ na-eto eto na laabu cell omenala agụụ mmetụta, cryotherapy, mmetụta, na iji ahaziri ihe na Micro-nanolayers na pores ... ụfọdụ etinyere ha na ijikọta niile nkebi nke technology.

A pụrụ iche bụrụ na ụdị imepụtaghachi ndu ọmụma taa bụ, ihe atụ, PCR technology (Polymerase Chain Mmeghachi omume), kọwara theoretically na 1971 na ihe amụma na 1983.

Na PCR, dị ka a maara, pụtara multiplexing (multiplication, multiplication, ugboro ugboro Iṅomi, amplification) nke ndu ọmụma n'ụdị DNA (ya iberibe).

The ụgbọelu nwere ọtụtụ n'ime ya ihe onwunwe ndu, bughi ihe ọmụma banyere a-eto eto ike cell, nke na-- na cellular ọdịnaya kwekọrọ ekwekọ na cell ntorobịa - na ẹkenam n'ime ahu nke onye ọrịa (ahịa), na nke ya onwe ya ike somatic mkpụrụ ndụ na-na mbụ napụrụ.

Ịza ajụjụ.

Okwu ahụ bụ "na-eto eto cell" na-ezo aka ọnọdụ na ọdịnaya nke mkpụrụ ndụ kwekọrọ na ya na-eto eto, ya bụ - nke mbụ ya n'oge mitosis. A na-ajụ nwere a biologically-onye ozi, mgbe ndinọ ka a na-ekwe nkwa esịmde na penetrates n'ime niile somatic mkpụrụ ndụ. A ga-esi otú a gụrụ otu ugboro niile somatic mkpụrụ ndụ. Cheta: ngafe biologically-onwe na nkwado nye site na ya multiplication (multiplication). Ka ihe atụ, ndu ọmụma na-amịpụtara si 10 eto eto (ma ọ bụ rejuvenated) mkpụrụ ndụ nwere ike multiplexed ruo ọtụtụ nde mmadụ ma ọ bụ ọtụtụ ijeri. N'ihi ya, ihe na ozi a ga-webatara site n'oru nke ọtụtụ nde mmadụ na ọtụtụ ijeri ndị a na mkpụrụ ndụ!

Napụrụ ike somatic mkpụrụ ndụ na-ekwe nkwa na-apụghị ime nke na mberede nyefe nke ọrịa na rejuvenating ahụ, mmejuputa iwu maka nzube nke ịkwụsị BIMF ịka nká ma ọ bụ rejuvenation.

N'ihi ya, ahụ na-enwe ndidi ga-enweta karịa nke ya (nditịm biologically onye!) Ozi banyere gị na-eto eto na ala - ala nke nwa ya mkpụrụ ndụ. Ngafe eto eto na ndị ozi na-ahụ na-ekwe nkwa iji kwụsị na-aghọ (ndetu) nwesịrị afọ metụtara mgbanwe na Filiks, na-- akwụsị ma ọ bụ rejuvenates nke merela agadi ndidi.

Uru na atụmatụ BIMF

(Bio-onye ọgwụ technology)

kwụsị ịka nká ma ọ bụ rejuvenation.

BIMF bụ onye na-agwakọta ikekwe nile di iche iche nke taa elu teknụzụ - nano-, bio-, cryogenic, agụụ, cell, Sol-jel, pharma, ọla kọpa, mikroinstrumentalnye - dị nnọọ mkpa ka ngwa nke ndụ usoro na n'otu oge ahụ nwere a n'otu - na "ise mmewere". Eji na plasma technology, elu-okpomọkụ agụụ ngwá maka nhazi na n'ichepụta ngwá egwú na laabu glassware.

The technology na-enye ohere rejuvenate dum, na ya iche iche akụkụ na anụ ahụ - na nke kwesịrị ekwesị mgbanwe usoro technology.

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