"Cefoperazone + Sulbactam": ntuziaka maka ojiji, analogs, reviews

Ugbu a, e nwere ndị a na nnukwu ọnụ ọgụgụ na-efe efe, nke fọrọ nke nta-agaghị ekwe omume na-aka n'ejighị ọgwụ nje. Ọ na-achọsi ike na ọgwụ nwere ike inwe mmetụta ọjọọ n'ahụ na a ọnụ ọgụgụ buru ibu nke microorganisms. Ndị a gụnyere ndị a "Cefoperazone + Sulbactam." More maara egosi maka ojiji nke a ọgwụ.

Hapụ ụdị na mejupụtara

The ọgwụ dị ka a powder maka ngwọta. Ọ na-ndinọ intravenously ma ọ bụ intramuscularly. N'ọrụ umi bụ na ego nke ceftazidime 1 g

Drug "Cefoperazone + Sulbactam" (ahia aha - "Sulperazon" ma ọ bụ "Sulperatsef") na ọ bụ nke a ìgwè nke antibacterial ọgwụ ọjọọ.

The pharmacological edinam nke ọgwụ

A ọgwụ bụ nke a jikọtara n'aka. Agwọ ọrịa "Cefoperazone" bụ a sara mbara-ụdịdị dị iche iche ude. O nwere a ezighị ezi mmetụta na kasị aerobic na anaerobic nje ntule.

Nkwadebe "Sulbactam" bụ irreversible inhibitor nke beta-lactamases. Ọ na-egbochi mbibi nke penicillins na cephalosporins, ebe ọ bụ na compound ngosi Synergy na ha.

The agwọ ọrịa "Cefoperazone + Sulbactam" na-akpa ya oghom mmetụta na mkpụrụ ndụ site inhibiting peptidoglycan, nke bụ akụkụ dị mkpa nke bacteria mgbidi.

Drug anyụpụ si n'ahụ banyere 8 awa nke mmamịrị. The ọkara ndụ nke banyere awa abụọ. Ọ bụrụ na onye ọrịa na-anata ọgwụ, na-ata ahụhụ ọrịa imeju, mgbe ọgwụ excretion abawanye.

Usoro JECFA "Cefoperazone + Sulbactam» - 24.42.11.228. Drug emepụta India.

Egosi maka ojiji nke ọgwụ

The ọgwụ na-owụt n'ihi na ọnụnọ nke na-efe efe na-triggered site microorganisms chebaara ifịk umi. Ndị a gụnyere:

• Pharyngitis.
• Tonsillitis.
• Bronchitis.
• mbufụt nke ngụgụ.
• Lung etuto.
• Na-efe efe nke urinary usoro, dị ka cystitis, gonorrhea, prostatitis, vulvovaginal.
• ENT ọrịa.
• Skin ọrịa nke na-efe efe ọdịdị: furunculosis, pyoderma, ahụ etuto na ndị ọzọ.

• Na-efe efe n'ime nkwonkwo.
• Sepsis.
• Meningitis.

The na nkà mmụta ọgwụ na-iwere dị ka a mgbochi ụfọdụ nje na nsogbu mgbe ịwa ahụ.

Nkwadebe "Cefoperazone na Sulbactam Dzhodas" na-na-egosikwa na peritonitis, cholecystitis, cholangitis na ndị ọzọ na intra-abdominal-efe efe. Nzube nke ọgwụ chọpụtara na oge nke ọgwụ na ọgwụgwọ regimens kwesịrị ịdị na-na site dọkịta.

Pụtara "Cefoperazone na Sulbactam Spencer" a na-kenyere maka nzube nke mgbochi.

Onye na-adịghị ike ikwu na-ewere ọgwụ ọjọọ

N'agbanyeghị dịgasị iche iche nke omume, nke a na ngwá ọrụ ike-anabata n'okpuru ụfọdụ ọnọdụ:

• Na ọnụnọ nke hypersensitivity ọgwụ ahụ.
• N'oge ara "Cefoperazone + Sulbactam" a na-contraindicated.
• Gbasara akụrụ hepatic odida na-achọ nnọọ anya ngwa.
• Na ọnụnọ nke afọ na a ọrịa ihe mere eme.

Tupu ịmalite ọgwụgwọ na a ọgwụ ị ga-ijide n'aka na-atụle na dọkịta gị ọnụnọ nke contraindications.

Ekwesighi mmetụta n'oge ọgwụ

Drug "Cefoperazone + Sulbactam" ahia aha bụ "Sulperazon" n'oge ọgwụgwọ nwere ike ime ka mpụta ìhè nke ndị na-esonụ mmetụta:

• Site urinary usoro nwere ike ịzụlite hematuria.
• Obi usoro nwere ike ikwu na a ọnụ ke ọbara mgbali vasculitis.

• Analysis ọbara n'oge ọgwụ ọgwụgwọ mgbe na-egosi a ọnụ nke haemoglobin, belata hematocrit, thrombocytopenia, eosinophilia, leukopenia na ndị ọzọ na abnormalities.
• Belata albumin etoju.
• Bilirubin encephalopathy na ụmụ ọhụrụ nwere ike ịbụ na jaundice.
• Na akụkụ nke eriri afọ tract ike dyspepsia, vomiting, ọgbụgbọ, na pseudomembranous afọ.
• Na akpụkpọ pụrụ iyi ihe ọkụ ọkụ, maculopapular ọkụ ọkụ, na oké itching.
• Laboratory ọmụmụ gosiri nhapụ imeju ọrụ ule.
• The ọgwụ saịtị soreness ọgwụ dị, mgbe ndinọ intravenously site catheter - phlebitis.
• Dịkarịa ala yiri ka na-enwe isi ọwụwa, ahụ ọkụ, na ihe ndị ọzọ anaphylactic Jeremaya mere nke organism.

Na omume nke ọ bụla ekwesighi ngosipụta mkpa atụle nke a nke na dọkịta gị. Ị nwere ike iji tụleghachi na onunu ogwu nke ọgwụ "Cefoperazone na sulbactam" ma ọ bụ kagbuo ya kpam kpam.

Gịnị nwere ike na-atụ anya na ihe ovadozu ọgwụ

Ọ bụrụ na i mee nke a ọgwụ n'okpuru ike nlekọta nke a dibịa, na ovadozu ị na-ekwesịghị iche, ma n'ihi na onwe-ọgwụ bụ mgbe o kwere omume. Ọ bụrụ na ahụ natara ọgwụ ukwuu karịa a chọrọ, e nwere ike ịbụ akwara ozi ọrịa, gụnyere ihe ọdịdọ.

Ọgwụgwọ na nke a na-rụrụ dị na mgbaàmà. Ndị kasị dị irè bụ hemodialysis.

Ọnụọgụ ọgwụ na Ọgwụgwọ Usoro

Ọ bụrụ na họpụtara na nkà mmụta ọgwụ "Cefoperazone + Sulbactam" ntụziaka ntuziaka na-atụ aro na igba ọgwụ intravenously ma ọ bụ intramuscularly. N'ihi na okenye ọrịa a kwa ụbọchị dose na-abụkarị site 2 4 grams nke nọ n'ọrụ mgwa. A ego a ga-kewara abụọ nkebi.

Ọ bụrụ na onye ọrịa nwere a siri ike ọrịa dose nwere ike mụbara ka 8 grams, nke a ga-kewara abụọ doses kwa ụbọchị. Ọ bụrụ na e nweghị ndị yiri adịghị ala ala ọrịa, ọtụtụ ndị ọrịa, na kwa ụbọchị dose na ego nke 12-16 grams anabata enweghị o mmetụta.

Na oge nke ọgwụ kpebisiri ike site dọkịta. Ihe atụ, mgbe na-adịghị mgbagwoju gonococcal urethritis ndinọ otu oge 500 mg nke ọgwụ.

Na ebumnuche nke mgbochi nke nsogbu mgbe a wasịrị nkwadebe ndinọ onye ọrịa 1-2 g intravenously otu awa tupu ọrụ. Nke a dose nwere ike ugboro ugboro mgbe 12 awa. Ọ bụrụ na ịwa ahụ a rụrụ na ụba n'ihe ize ndụ nke nsogbu ndị dị otú ahụ dị ka ọrịa, na prophylactic ochichi na-aga n'ihu 3 ụbọchị mgbe ogbako.

Ọrịa ndị nwere nsogbu na akụrụ, ọgwụ ọjọọ, "Cefoperazone + Sulbactam" e kenyere na a onunu ogwu nke bụghị karịa 4 grams kwa ụbọchị. Ọ bụrụ na e nwere nsogbu na nke imeju, na dose na-ebelata ọbụna okpukpu abụọ.

Ebe ọ bụ na ọgwụ ọjọọ nwere ike ndinọ intravenously na intramuscularly, e nwere ụfọdụ atụmatụ na ya ngwa.

Mgbe ndinọ intravenously ka a mgbaze maka powder ike ga-eji:

• 5% dextrose ngwọta.
• Saline.
• Akpali mmasị mmiri ogwu ogbugba.

Mgbe ndinọ intravenously, na ntụ ntụ na otu mkpọ a ga-etisasịwo ke 10 ml nke a kwesịrị ekwesị mgbaze. Ọ dị mkpa na-eche maka zuru mgbasa na ọgwụ ndinọ nwayọọ nwayọọ 3-5 nkeji.

Ọ bụrụ na ga na-atasị ọgwụ "Cefoperazone + Sulbactam" ntụziaka ntuziaka na-atụ aro 1 gram nke nọ n'ọrụ mgwa. Nke ahụ na-, ọdịnaya nke otu mkpọ a gbazee na 5 ml mmiri maka ọgwụ, wee tinye na infusion ngwọta, na-eweta ịta ka 20-100 mg / ml. Nyere ego nke ihe ngwọta na-atasị, mkpachapụ oge nwere ike ịbụ site 10 ruo 30 nkeji.

Intramuscular ochichi igbari powder ike ga-eji ma mmiri maka ọgwụ ma ọ bụ sodium chloride. The ruru na-eji dị ka ndị a: 0,5 g ngwaahịa buru 2 ml nke mgbaze.

Ebe ọ bụ na mgbe ndinọ ọgwụ ọtụtụ ime ihe mgbu na-agbanye site, ọ na-atụ aro na na nkwadebe ọgwụ ngwọta kwukwara "Lidocaine 2%", ma naanị na ọnọdụ nke onye ọrịa na bụghị anabata ọgwụ.

N'ihi na ọ bụla na-efe efe ọrịa injections inye a mmetụta dị mma bụ ngwa ngwa, otú ahụ ka injections na-ndinọ na "Cefoperazone + Sulbactam." Mbadamba na-ukwuu iji nwayọọ.

Iji nke ọgwụ na ụmụ

Na-amụ ije na-ata ahụhụ site na-efe efe nke ọ bụla ọgwụ nje nnọọ ike ime. The kwa ụbọchị dose nke nọ n'ọrụ umi cefoperazone isi kwesịrị site 50 ruo 200 mg kwa kilogram ahu arọ nke nwa. Ndinọ ọgwụ ga tụnyere akụkụ site kewara n'ime nkebi abụọ.

Desirably, kwa ụbọchị dose adịghị gafere 12 F. Ọ bụrụ na ndị nkà mmụta ọgwụ na-agbara bolus, na unit dose ekwesịghị gafere 50 mg / n'arọ.

Ụmụ ọhụrụ nwekwara ike ga-ndinọ 50-200 mg nke ọgwụ kwa kilogram arọ ahụ, nkerisi ya abụọ nkebi site 12 awa. Dabere na ọtụtụ afọ nke bara uru ngwa nke ngwá ọrụ na ọgwụgwọ nke ụmụ, ọ nwere ike kwuru na doses ruo 300 mg kwa kilogram nke ahu aro kwa ụbọchị na-ọma anabata ụmụaka, ọbụna ọnụnọ nke nje meningitis.

Iji ọgwụ n'oge ime

Medicine na-arụsi ọrụ ike mgwa ceftazidime machibidoro inyom na ọnọdụ naanị mgbe ndị dị otú ahụ na-ekwu, ebe uru n'ihi na nwanyị ọtụtụ ugboro ukwuu karịa ndị nwere ihe ize ndụ nye ndị na-emepe emepe nwa. Ọ bụrụ na ị chọrọ itinye ogwu n'oge ara, dọkịta ga nwere ike ikwu na n'oge a nyefee nwa ha wuru nri.

Mmekọrịta ndị ọzọ ọgwụ ọjọọ eme ihe

Drug "Cefoperazone" na ya pharmacological Njirimara na-adịghị jikọtara na ihe aminoglycoside. Ọ bụrụ na e nwere mkpa na ọgwụ ndị a abụọ dị iche iche nke ọgwụ ọjọọ eme ihe, ha na-ndinọ ke ụdị intermittent ochichi via abụọ dị iche iche catheter.

Co-ochichi nke ọgwụ na a thrombolytic, antiplatelet na NSAIDs enwekwu ihe ize ndụ nke ọbara ọgbụgba.

N'ihi na ọrịa na akụrụ nsogbu na n'ikuku nke a agwọ ọrịa "Cefoperazone Sulbactam" ọnụ na aminoglycosides na diuretics fraught mmepe nke nephrotoxicity.

N'oge ọgwụ na "Cefoperazone" ekwesighi ịṅụ mmanya, ma ọ nwere ike ime ka ndị na-esonụ mgbaàmà:

• Ọgbụgbọ.
• Vomiting.
• Oké isi ọwụwa.
• Tachycardia.
• ẹsụhọde ọbara mgbali.
• Abdominal mgbu.

Tupu ịmalite ọgwụgwọ na a ọgwụ, ị ga-agwa dọkịta gị banyere ihe niile ọgwụ na-iwere na oge.

Gịnị na-eme ma ọ bụrụ na ị na-contraindicated pụtara "Cefoperazone"? Analogs nwere ike dochie ya.

Ụfọdụ nuances nke iji ọgwụ

N'oge ọgwụgwọ na a ọgwụ kwesịrị ịkpachara anya karịsịa ndị ọrịa nwere nfụkasị Jeremaya mere na-emekarị hụrụ. Ihe ize ndụ nke a na ụba uche bụ fraught na ọbụna na-egbu egbu. Ọ bụrụ na n'oge ọgwụ hụrụ ọbụna obere nfụkasị Jeremaya, ọgwụ "Cefoperazone + Sulbactam" ga-ebulikwa ozugbo na-eji dochie ya n'ụzọ ndị ọzọ.

Ọ bụrụ na onye ọrịa nwere a siri ike ruo n'ókè nke mgbochi nke biliary tract, imeju ọrịa akụrụ, ọ na-achọ onye dose ukpụhọde nsogbu. Na ọnụnọ nke gbasara akụrụ na hepatic impairment ga-ahụ mgbe nile nlekota ịta nke nọ n'ọrụ ọgwụ umi ke ọbara. Ọbụna na-enweghị akara dose ekwesịghị gafere 2 grams kwa ụbọchị.

Na ụfọdụ ndị ọrịa n'oge ọgwụgwọ na "Cefoperazone" na-emepe emepe vitamin K erughi Ọtụtụ mgbe, nsogbu a pụtara na ndị nwere a gahiere agahie nri, malabsorption, ma ọ bụ na-ata ahụhụ ruo ogologo oge bụ na igba ogwu n'akwara nri. Ọrịa ndị a na-emeso ya na anticoagulants, mgbe nile mkpa inyocha ihe prothrombin oge, na, ma ọ bụrụ na ọ dị mkpa, inye onye ọzọ na oriri nke vitamin K.

Ọ bụrụ na ị chọrọ a ogologo ọgwụgwọ, "Cefoperazone", ọ bụ omume na-eme ka ọtụtụ ndị Micro-ntule na-adịghị susceptible a agwọ ọrịa. Ọ na-achọ a oge nlekota nke egosi nke ịrụ ọrụ nke akụkụ ahụ ndị ahụ, karịsịa, imeju, akụrụ na hematopoiesis. Nke a dị mkpa karịsịa na ọgwụgwọ nke neonates, ụmụ ọhụrụ na ụmụ ọhụrụ na akaghi aka ụmụ ọhụrụ.

N'oge ọgwụgwọ kwesịrị izere na-akwọ ụgbọala na-arụ ọrụ ndị na-achọ ihe ịta.

ọgwụ analogues

Ọ bụrụ na anyị na-atụle ọ bụla ọgwụ, abụọ iche iche nwere ike kwuru preparations maka ya analogs na synonyms. N'ihi synonyms agụnye ọgwụ na ha mejupụtara nwere otu n'ọrụ mgwa. N'ihi na "Cefoperazone" ọgwụ ọjọọ, ndị a bụ:

• "Bakperazon".
• "Sulzontsef".
• "Sulmomer".
• "Sultsef".
• "Tsebaneks".
• "Paktotsef" na ndị ọzọ.

Ọ bụrụ na anyị na-atụnyere ndị agwọ ọrịa "Cefoperazone" analogs nwere ike nwere ihe ọzọ mmiri, nke na a isi umi nwere ubé dị iche iche mmetụta. Ọ bụ ya mere na oke nke ndị dị otú ahụ ọgwụ ọjọọ eme ihe a ga-bịakwutere akpọrọ na-anabata ha naanị na ndenye ọgwụ.

Ìgwè ndị ọzọ dị analogues bụ ọgwụ na otu pharmacological edinam. Ọ bụrụ na ị na-ọgwụ ọjọọ, "Cefoperazone + Sulbactam" analogues nke otu a bụ:

• Ntụ ntụ "Azaran" maka igba ogwu n'akwara injections.
• "Axons."
• Ntụ ntụ maka ọgwụ "Bestum".
• "Vitsef".
• "Klaforan".

• "Kefoteks".
• "Tsedeks" capsules.
• "Tsemideksor" (mbadamba).
• "Tsefantral" na ọtụtụ ndị ọzọ.

Ọbụna na otu pharmacological mmetụta nke ọgwụ n'ihi na nke dị iche iche-arụ ọrụ bekee nwere ike dị iche iche na mmetụta na-ahụ, n'ihi ya, anaghị na-ahọrọ ha onwe ha na nkà mmụta ọgwụ, nke dabeere na ntuziaka maka ojiji.

nleba

Ndị ọrịa na-adịghị ugboro malitere "Cefoperazone + Sulbactam" ọgwụ maka ọgwụgwọ nke na-efe efe, kwuru na ya elu arụmọrụ. Ọtụtụ na-ekwu na genitourinary na-efe efe pụrụ ịgwọta agwọta ngwa ngwa na-enweghị nsogbu.

Mama anyị ụmụaka na-ahapụ pro ọgwụ "Cefoperazone" pụtara nti reviews. Ha chọpụtara na ụmụaka anabata ọgwụ ọma ọbụna ọnụnọ nke ngalaba-morbidities. Ọ ga-eti na ndị dị otú ahụ ọgwụ ga-rụrụ naanị na a na ụlọ ọgwụ, karịsịa a mụrụ ọhụrụ.

The mbanye nke ọ bụla ọgwụ nje na-achọ ihe anya na-arụ ọrụ nke digestive usoro. Ịnọgide na-enwe nguzozi nke microflora, ọ na-achọsi ike ka n'out oge na-enweta kwesịrị ekwesị ọgwụ, n'ihi na ihe atụ, "Linex". Ajụjụ a nwere ike mgbe niile-atụle na dọkịta gị.