Interstitial nephritis: mgbaàmà na ọgwụgwọ nke akụrụ mbufụt

Interstitsionalny nephritis bụ mkpali ọrịa akụrụ, nke etịbe tumadi na-emetụta ndị n'etiti anụ ahụ na akụrụ tubules.

The ọrịa nwere ike ime n'oge ọgwụgwọ na ọgwụ (ọzọ ọgwụ nje, na a nta diuretics, sulfonamides) nakwa dị ka mgbe ọ gụrụ bacteria, nje, na ọrịa. The daa ọrịa dabeere lymphohistiocytic infiltration eme na etiti gbasara akụrụ anụ ahụ mebiri ruru na mgbe n'okpuru ala akpụkpọ ahụ nke tubules. N'ụdị a dịghịzi okụre na autoantibodies ka akpụkpọ ahụ na-edozi. Dị ka a n'ihi nke ụbụrụ edema na mbufụt nke akụrụ anụ ahụ oyi akwa bụ a n'ibu mkpakọ nke ọbara arịa na tubular, belata gbasara akụrụ ọbara, abawanye mgbali vnutrikanaltsevoy, emecha amalite oliguria.

Mgbe nchoputa nke interstitial nephritis mgbaàmà ndị dị ka ndị. Mmalite nke ọrịa - nnukwu, agafe fever, polyuria, ma ọ bụ hematuria amalite akụrụ odida, e nwere ihe mgbu na ala azụ. The mbụ ihe ịrịba ama nke na onunu ogwu iche nke nnukwu interstitial nephritis protrude ọzọ na-amụba ahu okpomọkụ, nke nwere ike ga-metụtara eosinophilia na akpụkpọ eruptions. N'ihi na ọrịa ji agafeghị oke proteinuria, hematuria, na obere okwu, oliguria.

Nnukwu interstitial nephritis malitere ịrịa forms na-ewe ebe hemorrhagic fever na gbasara akụrụ ọrịa.

Diagnosis nke ọrịa ka na ọrịa akụrụ, nnukwu glomerulonephritis. Ọ bụrụ na-emepe emepe akụrụ odida ga-ekwe ndị ọzọ na-akpata.

Ọ bụ nnọọ ike na mgbe ụfọdụ agaghị ekwe omume iji chọpụta ihe kpatara nke-adịghị ala ala tubulointerstitial nephritis jikọtara ọgwụ ikpughe, ọrịa nje, ọrịa.

Mgbaàmà nke-adịghị ala ala interstitial nephritis iso na tubular ọrịa, ngwa ngwa na-emepe emepe okenye electrolyte disturbances (hyperkalemia, acidosis) Abuse ịta akụrụ ya. Na obere okwu, o kwere omume ọbara mgbali na proteinuria. Na ọkọlọtọ ọnọdụ nephrotic syndrome anọghị, ma ọ bụrụ na ọrịa progression interstitial nephritis fọrọ neolichim nke glomerulonephritis. The kasị dị ize ndụ ọgwụ ọjọọ, na-eduga na a na-adịghị ala ụdị ọrịa ahụ bụ ndị analgesics phenacetin, analgin, aspirin.

Mgbe ụfọdụ, ndị inyom 35-40 afọ, migraine, ịda mbà n'obi, afo ọnyá, kwuru, analgesic interstitial nephritis. Na nke a na-ahụkarị Nchikota na aseptic leukocyturia eguzogide gbasara akụrụ colic ngosipụta na oké njọ hematuria, gbasara akụrụ size Mbelata, polyuria, anaemia.

The ọrịa amalite na njikọ na ọrịa ndị ọzọ, nwere a doro anya dịghịzi pathogenesis (ifịk -adịghị ala ala ịba ọcha n'anya, lupus systemic lupus erythematosus).

Interstitial nephritis na ụmụaka nwere ike mepụtara na dizembriogeneza gbasara akụrụ anụ ahụ, urinary tract anomalies, imebi nke uric acid na calcium oxalate metabolism.

Mbuso ọrịa na-eji etiological ọgwụgwọ nke nje ọnya amalite iwepu na-elekwasị anya nke ibute ọrịa. Mgbe na onunu ogwu ụdị - kwụsị ịṅụ ọgwụ ọjọọ, nye iwu ka a na-eri enriched na vitamin na ịṅụbiga mmanya ókè. Na enweghị ezi ihe kenyere glucocorticoids ịrụ hemodialysis, ewepu na ojiji nke diuretics na mmepe nke nnukwu gbasara akụrụ odida. Ọ dịkwa mkpa izere ụba ojiji nke analgesics na-aṅụ ọzọ.