Medicine "Trimektal": ntuziaka maka ojiji, price, analogs na reviews

"Trimektal", nke bụ ntọala bụ isi trimetazidine ifịk umi bụ ìgwè nke ọgwụ ọjọọ na-emegide hypoxic ihe nke agwa, na-eji tumadi na Cardiology n'ihi nzube nke stabilization nke obi usoro. The agwọ ọrịa a na-emekarị ọrụ dị ka na-akwado / mgbazi pụtara n'ihi na mgbagwoju ọgwụ na site mmetuta nke cellular metabolic usoro na-eme ka n'ozuzu mma nke ọrịa na-arịa.

Hapụ ụdị na mejupụtara

E nwere ọtụtụ ụdị nke na mmepụta "Trimektal" ọgwụ ọjọọ. Ntuziaka maka ojiji na-egosi na nke a nwere ike ịbụ a siri ike gelatin Capsule (10/20 site blisters ma ọ bụ polymeric nkeji nke capacitance mmiri 60 nkeji) na mbadamba shei akpụkpọ ahụ, retarding ntọhapụ nke ndị reagents (blisters na 10/20/30 iberibe. ọ bụla plastic nkwakọ na 60/100/120 PC.). The isi akụrụngwa ma ikpe na-eme nke trimetazidine dihydrochloride. Otú ọ dị, ọdịdị nke ọgwụ, nke bụ pụta ụwa belatara ọnụego nke absorption na metabolism, nwere a dị iche iche ahia aha - "Trimektal CF".

pharmacological mmetụta

Ka antihypoxic nkwadebe "Trimektal" (ntuziaka maka ojiji nke a na-enye a doro anya nhazi ọkwa nke ọgwụ na mesiri ike mkpa ma ya antioxidant Njirimara) nwere a kpọmkwem "ginger" mmetụta na ụbụrụ akwara ozi na cardiomyocytes. N'ihi ya ọgwụ ruru enwekwu ha arụmọrụ. Ọbọ cytoprotective mmetụta - a eke N'ihi nke uto nke ume nwere nke mkpụrụ ndụ na ndabere nke zuru njikarịcha nke oxygen oriri mode.

N'ọrụ umi adịghị ekwe ka asynchronous mkpi nke myocardium site "nchekwaba" nke chọrọ kacha nta nke phosphocreatine. Bụrụ na nke mebiri acid-isi ịha "Trimektal" akara ịta nke calcium na sodium, i.e. ya egbochi oké ìgwè nkwekọrịta ndị a, ndị na cardiomyocytes na n'out oge apụta ihe potassium ion nguzozi na mkpụrụ ndụ. Na-alụ na rịaworo na nkà mmụta ọgwụ-egosipụta onwe ya dị ka a neutralizer mgbọrọgwụ: Mbelata nitrate oriri na-eduga ná eziokwu na mgbe 14 ụbọchị nke ọgwụ na ọrịa na-ahụ ọganihu nke iguzogide ahụ nchegbu (uru nke ọbara mgbali tụlee otú ahụ belata).

Absorption na metabolism

Pharmacological kinetics nke ọgwụ "Trimektal" ntuziaka maka ojiji kọwara na-ele ya ntọhapụ iche-iche. Karịsịa, na ọdịnaya nke Capsule, na-echefu n'ime ahu ngwa ngwa (na fọrọ na full) gbara nkeji gị. Awa abụọ mgbe na-anata kacha hụrụ plasma ịta nke reactants. A otu dose of 20 mg nke nọ n'ọrụ akụrụngwa akowa na 55 and / ml.

N'ihe gbasara ogo nkesa nke ifịk ifịk mmiri, ịkọ ka plasma-edozi, na-emekarị adịghị gafere 16%. Otú ọ dị gistogematicalkie trimetazidine merie ihe mgbochi pụtara mfe. Banyere 60% nke dose ọ na-anyụpụ agbanweghi agbanwe na mmamịrị, na nke mbụ 50% - n'ime 4-5 awa.

N'aka nke ya, "Trimektal CF" (mbadamba ụdị n'ichepụta), ekele pụrụ iche membranes, na-enye kacha ịta na plasma reactants awa atọ. The ọkara ndụ, dabere na afọ nke ọrịa nwere ike ịbụ 7 na 12 awa.

egosi maka

Ikpe nke ọgwụ ọgwụ nlekọta "Trimektal" ntụziaka ntuziaka na-akọwa na-esonụ:

• mgbochi nke rịaworo pectoris (dị ka akụkụ nke mgbagwoju ọgwụgwọ adọ);
• disruptions chorioretinal vaskụla okike;
• dizziness kpasue ọtọ imbalances nke obi usoro;
• ikpe impairment (ngụkọta ischemic Filiks ke vestibular ngwa).

Ke adianade do, dibịa nwere ike ikpebi ma ruo ogologo oge iji ọgwụ na liquidation nke Baịbụl hiwere isi n'ebe erosions nke retina.

The usoro nke na ngwa ma na-atụ aro usoro onunu ogwu

Ọgwụ e ji ọnụ na ozugbo n'oge nri. Duration nke N'ezie atọrọ dọkịta (na ndabere nke a zuru ezu ike nnyocha na-eme nchoputa).

N'ihi na a Capsule ụdị omume nkezi ọnụego nke 40-60 mg / ụbọchị (mkpa ka na-aṅụ 2-3 ugboro).

N'ihe banyere nkwadebe "Trimektal MV" (ntuziaka maka ojiji na a na-ekwu bụ dịtụ iche iche si n'elu na-atụ aro), emekarị nyere otu mbadamba na ụtụtụ na mgbede.

mmetụta

Yana rụọ mmetụta mgbe ụfọdụ etịbe ma mmetụta nke ifịk ifịk mmiri. Banyere omume nfụkasị Jeremaya ka ojiji nke ọgwụ "Trimektal" nkwadebe ntuziaka maka ojiji, ego nke na-eso - ọrịa na-ahụ ike, kwuru, sị:

• na ụfọdụ ndị ọrịa e nwere ike ịbụ obodo iyatesịt nke anụ;
• ruo ogologo oge iji ọgwụ bụ nnọọ obere aghara hụrụ nri usoro (ọgbụgbọ, vomiting);
• mgbe ụfọdụ na-adịghị mma na ya pụta mgbe mbanye kwupụtara na isi ọwụwa na oké isi ọwụwa;
• ọbara akara na obi muscle mgbe ụfọdụ doro oké ibu, nke na-egosi mkpa ọ dị ka usoro onunu ogwu Mbelata.

Dịtụ ọgwụ "Trimektal MV" ntụziaka ntuziaka na-ekwu:

• ịzụlite orthostatic hypotension na guzobe "ime ihiere" na ya ihu bụ eleghi anya (ihe na-erughị otu nhazi ndidi kwa puku);
• ihe ahaghị nhata na digestive tract (abdominal mgbu, afọ ọsịsa, vomiting, wdg ...) - ezi mgbe (ihe karịrị otu narị mmadụ ikpe na-ewere ọgwụ).

Ke adianade do, e nwere ike ịbụ ndapụta ebe ojiji nke mbadamba na gbanwetụrụ ntọhapụ nke reagents pụrụ ịbụ ihe kpatara reversible ike ọgwụgwụ, tremor, akinesia, na urticaria.

Contraindications nhọpụta

Anyị tụlee mgbochi hypoxic pụtara "Trimektal". Ntuziaka maka ojiji, price nke ọgwụ, ọgwụ aha, guzo-ins, nakwa dị ka a dịgasị iche iche nke ọkachamara echiche adade ke akụkọ a iji mara onye nwere mmasị na-ege ntị. A ọgwụ nwere ụfọdụ contraindications dokwara mkpa ka ụdị nile nke ntọhapụ (capsules / mbadamba).

Ọgwụ na-adịghị gosiri ma ọ bụrụ na:

• chọpụtara gbasara akụrụ insufficiency (bụrụhaala na nwechapụ <15 ml / min);
• onye ọrịa nwere mgbaàmà nke ọtọ ọrịa nke imeju;
• onye ọrịa na-adịghị eru afọ iri na asatọ afọ;
• deere nnukwu anabata ọgwụ akụrụngwa.

Tinyere ihe ndị ọzọ contraindications - ime na lactation.

Adọ aka ná ntị na usoro nke iji ọgwụ na mmekọrịta

"Trimektal", ego nke nke dịgasị ọtụtụ (dabere n'ụdị nke na mba nke rụpụta -. 300-1100 rubles), adịghị kpughere otú ụfọdụ dị oké njọ na-adakarị nnyocha na isiokwu nke na nkwukọrịta ndị ọzọ ọgwụ. N'ihi nke a, na-ekwu banyere usoro nke mkpakọrịta mgbagwoju mmetụta nwere ike na-dabere na Nchoputa nwetara dị ka a n'ihi nke laabu ọrụ na trimetazidine - isi akụrụngwa nke kọwara agwọ ọrịa. Ọ na-ahụ kwuru na trimetazidine-arụ ọrụ nke mgbochi ischemic ọrụ nke ampilifaya, nke bụ na ya pụta nke n'ikuku nke ọzọ antianginal ọgwụ ọjọọ. Kpọtụrụ ndị ọzọ ụdị metụtara reagents "Trimektala" enweghị hụrụ.

Special ntuziaka ka nhọpụta nke ọgwụ:

• ike ga-eji na-n'ụbọchị ndị mbụ nke ụlọ ọgwụ, ma ọ bụrụ na na na-chọpụtara na-ejighị n'aka rịaworo (ma ọ bụ ebe na-PIS);
• Relation n'etiti oriri nke capsules (mbadamba) 'Trimektala "na omume nke ọrịa Parkinson, nke a na-egosipụta na amplification / attenuation nke tremor, odi ọzọ nlekota nke onye ọrịa (ya bụ oge nnyocha ọkà mmụta ọrịa akwara);
• maka ọrịa tọrọ afọ 75 nke ọgwụgwọ N'ezie bụ fraught na nsogbu nke akụrụ, n'ihi ya, mkpebi ikpeazụ maka dọkịta;
• mebiri psychomotor Jeremaya mere iwe na trimetazidine, - bụ ntọala iji na-egosipụta na kwesịrị ekwesị ojiji nke ọgwụ n'ebe ndị ọrịa bụ nke ọgwụ, na ya ọkachamara ọrụ e jikọtara ya na iyi egwu nke inweta ọrụ na-unan.

Isi analogues

The kasị substitutions nkwadebe "Trimektal" (analogs ifịk umi bụ nke na-trimetazidine):

• "Trimetazidine-Biocom MV", Russia;
• "Trimetazid", Poland;
• "Trimethyl", India;
• "Antistius", Russia;
• "Medarum 20", Russia;
• "Preductal MV", France;
• "Rimekor MB", Ukraine.

N'agbanyeghị general chemical usoro, ọnyà ihe na ahụ nwere ike ubé dị iche iche karịa mbụ. Ya mere, na oke nke a akpan akpan ọgwụ - ihe ruuru nke dọkịta.

Medicine "Trimektal": echiche na comments

Health nsogbu metụtara ihe iseokwu nke ọbara fibrillation, mgbe mgbe, na amụ thematic mkparịta ụka. M na-achọ ịnụ echiche nke ọrịa na ndị na-ike na-akụziri banyere ọgwụ ọjọọ, "Trimektal" (reviews, onye na-achọkarị mma obi ụda) adịghị enwe ihe isi ike na-achọta ihe ọmụma. Otú ọ dị, ọbụna a elu elu analysis nke echiche na-egosi na lekwasịrị specificity emetụta ziri ezi na-ekwu. Mgbe kwuru ọgwụ ọtụtụ mgbe kenyere "na mgbagwoju," ya bụ, tinyere ndị ọzọ ọgwụ.

Dị ka ihe atụ, a nnọọ nnukwu ìgwè ndị ọrịa, na na Nchikota - na ọrịa ndị na-wara ọgwụgwọ N'ezie na ndabere nke "Trimektala" na ha nyochaa akụkọ converge ke eziokwu na ịrịba ọganihu curbing dị otú ahụ ọrịa dị ka ala ala ọbara mgbali na ịrịa ọrịa obi, ọgwụ na-adịghị nyere .