Ogbenye ọbara clotting.

Taa, a na-agba ọbara aghara nwere ike ịbụ n'ihi a ọnụ ọgụgụ nke ọrịa nke ma ndị ọbara (hemophilia, thrombocytopenia, Villebranta ọrịa, wdg), na vaskụla ọrịa na (iche iche vasculitis).

Gịnị bụ clotting? na ihe mere ọ na-a mebiri ime?

Blood dị ka ahụ ọmụmụ rụrụ bụ isi ọrụ e kenyere ya. Ke akpa itie, ọ bụ nyefe nke oxygen na oriri na-edozi nke anụ ahụ. Iji hụ na kwesịrị ịrụ ọrụ nke ahụ bụ a isi mmezi nke homeostasis. Milieu intérieur agbanwe na n'okpuru nduzi nke dị iche iche na mmetụta ya n'ebe kwekọrọ ekwekọ mgbanwe na ikwado mmegharị na lanarị - nke a bụ homeostasis.

Ogbenye ọbara clotting bụ ihe ọ bụla ọzọ ma a nkwarụ na otu nke homeostatic usoro. Nọmalị, na ahụ mmadụ Filiks nọgidere ime na coagulation egbochi mkpụkọ nke ọbara (thrombi) na ha lysis (mgbasa). Mgbe anụ unan ma ọ bụ ndị ọzọ ahụ anụ ahụ na-adị na-ebighị nke a cascade nke zipụta ha n'usoro Jeremaya mere. Ebe ọ bụ na n'oge e guzobere a ọbara clot na ọnya n'elu metụtara dị iche iche bekee ndị dị otú ahụ dị ka cellular (i.e., ndị nke kewapụrụ akwusila mkpụrụ ndụ, ịgwa coagulation usoro n'ụzọ anụ ahụ ike n'ezi) na acellular (ihe). Adịbeghị anya synthesized isi na imeju nke ya olu, dara ogbenye ọbara clotting mgbe egosi imebi na ịrụ ọrụ nke ahụ a. ọrịa na-ejikarị mere site butere n'aka daa ọrịa agwa ọrịa ndị dị ka ọrịa na haemophilia Villebranta.

Ọtụtụ n'ime ndị ihe nke ọbara coagulation na-synthesized si protein (dị iche iche amino asịd), nke bụ ya mere mgbe ọ bụ erighị nri na-na-emepe emepe ogbenye ọbara clotting.

Ọgwụgwọ nke ọrịa a na akpa ebe, iji na iwepu etiological oge, ya bụ, iwepụ ihe mere nke mere ka ọrịa ahụ. Na enweghị ekwe omume nke ikpughe na etiological njikọ, na-emetụta ndị pathogenic mmetụta nke pụtara utịp ke usoro mmepe nke enweghị nchịkwa ọnọdụ. Otú ọ dị, ọbụna ndị a abụọ variants nke usoro nke ọgwụgwọ mmetụta na-adịghị eme mgbe nile ka ndị ofufe nke mgbaàmà na ogbenye ọbara clotting nọgidekwara. Na ikpe, na-eji ọzọ nhọrọ kama mmetụta na daa ọrịa na na gburugburu ebe obibi njikarịcha (homeostasis) na oge.

Otú ọ dị, mgbe na-ekwu banyere ọrịa a, tinyekwara banyere ndị dị otú ahụ a ọnọdụ, dị ka elu ọbara clotting. Osobo a ọnọdụ nke adịghị ikpeazụ, ma ha na-ekwesịghị ileghara, dị ka ndị na-esi nwere ike ịbụ nnọọ oké njọ. Otu n'ime ihe ndị mere na-eduga ndim na N'ihi mụbaa ọbara clotting, ndị na-esonụ:

- ukwuu ọmụmụ ọnwụ n'ihi polyuria (Ugboro urination), vomiting (mgbe multiple na-achịkwaghị) ma ọ bụ oke Burns (n'ihi propotevanie plasma na ọnya n'elu)

- n'iru ma ọ bụ fermentopathy mbuso agha na-eduga na a mgbanwe AAR

- ime (n'ahụ mgbanwe ọbara rheology)

- imeju ọrịa na (ọrịa njikọ nke enzymes na homonụ)

- akwadebe coagulation syndrome intravascularly

Mụbara clotting pụrụ iduga ọbara stasis na thrombus guzobere n'ime ọbara arịa. Usoro a na-enye ịrị elu thrombosed ischemia nke akụkụ na anụ ahụ. Ọgwụgwọ na nke a na-anọchi anya iwebata ọgwụ ọjọọ na igbari egbochi mkpụkọ nke ọbara (e.g., streptokinase na alteplase) na ọbara thinners. Ọ bụrụ na a ọbara clot kpam kpam nanị ọbara na ahụ, e necrosis.