Ọgwụ "Citalopram": reviews nke dọkịta

Otú ọma a ọgwụ ndị dị otú ahụ dị ka "citalopram"? Nyocha nke dọkịta banyere nke a ọgwụ ngwaahịa atụle ihe ndị a n'isiokwu a. Ọzọkwa, ọ na-enye ihe ọmụma banyere ihe na-akpata mmetụta, kwuru, sị n'aka, otú kụziere ya kwesịrị ekwesị n'ikuku nke ihe pharmacodynamic Njirimara ya nwere.

Mejupụtara, nkọwa nke ọgwụ, ya udi na mbukota

Na ihe ụdị ike ịzụta ọgwụ "Citalopram"? Nleba na-ekwu na ụlọ ahịa ọgwụ yinye bụ ngwá ọrụ na-ere ọgwụ ụdị lenticular na okirikiri udi, kpuchie na a na-acha ọcha film mkpuchi. The cross sectional a na nkà mmụta ọgwụ nwere a ubé acha n'ime oyi akwa.

Ihe e lere "Citalopram" ọgwụ ọjọọ? Ntuziaka, reviews kọrọ na-arụsi ọrụ ike mgwa nke ọgwụ bụ a umi nke otu aha - citalopram, nke na-dị n'ụdị hydrobromide. Banyere inyeaka mmiri, na-eji dị ka microcrystalline cellulose, pregelatinized starch, na magnesium stearate.

Ọ kwesịkwara kwuru na nke a film mkpuchi gị n'ụlọnga esịnede polyvinyl mmanya, Opadry II, macrogol, talc na titanium dioxide.

Na ire ahuta ọgwụ abatakwa ngwe mkpụrụ ndụ mere nke ịkwanyere ma ọ bụ aluminum, nke na-packaged ke a igbe mere nke kaadiboodu.

Pharmacodynamic e ji mara antidepressant

Gịnị bụ ọgwụ "Citalopram"? Nyocha na-ekwu na nke a bụ ihe antidepressant. Ya usoro nke edinam jikọtara suppression nke (nhọrọ) serotonin reuptake ogbugbo ugbu ke synapses nke akwara mkpụrụ ndụ, nakwa dị ka di ntakiri utịp ke reuptake nke neurotransmitters dopamine na nọrepinefrini. Ọ ga-kwuru na ngwá ọrụ na-adịghị na-egosipụta ike na-eme na a dịgasị iche iche nke na-anabata ya (na ụfọdụ serotonin, dopamine, H1-histamine, adrenoceptors, m-cholinergic anabata, Geba anabata na benzodiazepine anabata).

Anyị apụghị ikwu na ọgwụ "citalopram", reviews nke nke na-depụtara n'okpuru ebe a, ọ na-enyere iji melite ọrịa na ọnọdụ, suppresses nchegbu, na-ebelata nchegbu, nchegbu, eliminates dysphoria, na aka chaa. Ke adianade do, ọ fọrọ nke nta mgbe na-akpata a soporific mmetụta.

Dị ka ndị ọkachamara, a ufọk ufene utịp a ọgwụ hụrụ mgbe 7-10 ụbọchị mgbe na-aga n'ihu iji.

Kinetic ike agwọ ọrịa

Gịnị bụ ihe e ji mara nke pharmacokinetics nke ọgwụ "Citalopram"? Ibọrọ kọrọ na ya elu ịta nke nọ n'ọrụ umi ke ọbara pụtara n'ime awa anọ mgbe ingestion. Mgbanwe ndị na ya larịị bụ linear.

The bioavailability nke ọgwụ na-eru nso 80%, na nkekọ na-plasma-edozi bụ 79%.

N'ime ọbara citalopram bụ ugbu ke akpasarade ụdị. Nke a na umi bụ gbanwee site ọxịdashọn, demethylation na deamination. The ọkara ndụ-nke a na akụrụngwa bụ 1.5 ụbọchị. Ọ kpọpụrụ na mmamịrị na site na nsia tract.

Egosi antidepressant ọgwụ

Gịnị mere anyị mkpa a ngwá ọrụ ndị dị ka "citalopram"? Nyocha nke dọkịta na-ekwu na ọgwụ na-egosi na n'ikuku na:

• masịrị aghara;
• dara ya mbà ji nke oké na-agafeghị oke.

Ọ kwesịkwara kwuru na nye iwu a ọgwụ ga-enwe ahụmahụ ọkachamara.

Contraindications ọgwụ designation

N'okpuru ihe ọnọdụ nwere ike iji ọgwụ ọjọọ "Citalopram"?

Nyocha na-egosi ndị na-esonụ contraindications na eji nke a na nkà mmụta ọgwụ:

• obere ọrịa afọ (dị ka akwụkwọ ntuziaka, nchekwa na nrụpụta ọrụ nke ndị a mbadamba nke a afọ na-adịghị a guzosie ike);
• High uche nke onye ọrịa na citalopram, nakwa dị ka ọ bụla nke ya inyeaka bekee;
• mgbe na-anata na inhibitors nke monoamine oxidase tinyere moclobemide, selegiline, linezolid (n'ime izu abụọ mgbe discontinuation nke ha ochichi);
• mgbe na-ewere ọgwụ ọjọọ QT prolonging oge nke ECG (s tinyere pimozide) na congenital ogologo oge nkeji).

Antidepressant "Citalopram": ntuziaka maka ojiji

Ọbịa ọkachamara na-ekwu na echiche ga-enye ọgwụ, dabere na ọrịa na-arịa. "Citalopram" e jikwa ọnụ otu ugboro n'ụbọchị. N'ihi ya mbadamba na-agaghị ata ata ma asa ala na a obere ego nke mmiri mmiri.

Nke a na ọgwụ ike ga-eji n'oge ọ bụla nke ụbọchị n'agbanyeghị nke nri (ọkacha mma n'otu oge).

Mgbe ịda mbà n'obi ọgwụ na-amalite na-anata 20 mg kwa ụbọchị. Dabere na ọrịa onye Jeremaya mere dị ka nke ọma dị ka ogo nke ịda mbà n'obi, na onunu ogwu nwere ike mụbara ka kacha, i.e. na banyere 40 mg kwa ụbọchị.

Dị ka egwu aghara kwesịrị iwere ọgwụ "Citalopram"? Nyocha ọrịa na-ekwu na nke a na-arụsi ọrụ ike iji ọgwụ e nyere na a dose nke 10 mg kwa ụbọchị (1 izu), na mgbe ahụ, ọ na-ụba na 20 mg kwa ụbọchị. N'ihi ya, kwa ụbọchị dose nke ọgwụ nwere ike ịdabere na onye ndidi omume. Ekemende n'elu ego nke ọgwụ nwere ike ụba 40 mg kwa ụbọchị.

Persons tọrọ afọ 65 nke "Citalopram" afọ kenyere na a dose nke 10 mg. Dabere na ogo nke ịda mbà n'obi na onye nzaghachi, ọ nwere ike ụba na a kacha nke 20 mg kwa ụbọchị.

Mgbe isi ọrụ nke akụrụ, gụnyere ala ala gbasara akụrụ odida na-agafeghị oke ọdịdị na ogo nke na-adịghị ike, na ukpụhọde n'aka nke dosing Usoro a chọrọ. N'ihi na ndị na oké gbasara akụrụ insufficiency uwa chọrọ pụrụ iche na-elekọta na nhọrọ nke a ọgwụgwọ dose.

Mgbe isi imeju ọrụ, gụnyere hepatic odida na-agafeghị oke, nke dịkwa nwayọọ, nke mbụ onunu ogwu nke ọgwụ bụ 10 mg kwa (na nke mbụ 2 izu). Dabere na onye Jeremaya mere, ọ nwere ike mụbara ka 20 mg. Persons oké hepatic insufficiency uwa chọrọ pụrụ iche na-elekọta na dose nhọrọ.

Ndị na-a ala ọrụ nke isoenzymes ka CYP2C19, mbụ onunu ogwu bụ 10 mg kwa ụbọchị (2 izu). Dabere na onye omume, ọ nwere ike mụbara ka 20 mg.

Dị ka ntụziaka, na ọgwụgwọ mmetụta mgbe ochichi nke a isiokwu antidepressant bụ ugbua lụchara 2-4 izu. Na nke a, oge nke a N'ezie nke ọgwụ kpebisiri ike site ọnọdụ onye ọrịa na tolerability nke ọgwụgwọ. A, ọgwụ na-atụ aro ka ewe banyere 6 ọnwa.

kagbuo agwọ ọrịa

Ihe ndị mmadụ na-ekwu banyere ihe Jeremaya mere ime na a nkọ kwụsị ịṅụ ọgwụ ọjọọ, "Citalopram" reviews? Ònye were ngwá ọrụ a, ọ na-ekwu na ihe mgbaàmà ịda mgbe mberede cessation nke eji nke a ọgwụ bụ ahụkarị. Ọtụtụ mgbe, ndị ọrịa na-akọ nwayọọ dizziness, agbọ onunu, ike ọgwụgwụ, isi ọwụwa, ehighị ụra nke ọma, paresthesia, ịma jijiji, vomiting na ịma jijiji.

N'ihi ya, na ẹkụre ọgwụgwọ site na ngwá ọrụ kwesịrị kwusi ya nwayọọ nwayọọ, n'elu ọtụtụ izu. Nke a ga-ekwe ka ọrịa na-zere ndọrọ ego mgbaàmà. Dị ka a na-achị, ọ bụ zuru ezu ka izu abụọ, ọ bụ ezie na nke ọ bụla ọ ajụjụ ga-esi kpebie site a dọkịta na n'otu n'otu. Ya mere, n'ihi na ụfọdụ ndị ọ ga-ewe ọnwa 3 ma ọ bụ karịa.

Oghom Jeremaya mere mgbe na-ewere antidepressant

Olee ụdị ndị Jeremaya mere kwesịrị maara nke na-ezighị ezi agwa nke ọrịa, tupu na-ewere ọgwụ "Citalopram"? Nyocha banyere mmetụta na-ekwu na, dị ka n'ihe banyere iji ihe ndị ọzọ ọgwụ SSRI, na ndabere nke "Citalopram" ọrịa na-ahụ kwukwara ekwesighi mmetụta. Otú ọ dị, ọ ga-ahụ kwuru na ha niile bụ nke ukwuu na-adịghị ike na ndị na-akwụsị akwụsị.

N'ozuzu, oghom ihe na-esonụ ochichi nke a isiokwu ọgwụ hụrụ ke akpa izu 2 ọgwụ. N'otu oge ha bụ ọtụtụ na-adịghị ike na mma nke ọrịa na-arịa.

Ya mere, "Citalopram" nwere ike ime ka mmetụta dị otú ahụ dị ka:

• High uche, n'ahụhụ, anaphylactic Jeremaya mere, isi ọwụwa, nchegbu, depersonalization, ebelata libido, obi nchefu;
• ime ihe ike, mebiri orgasm na ndị inyom, Mania, nrọ iju, nchegbu, chee echiche igbu onwe, mgbagwoju anya, dizziness;
• iro ụra, mara jijiji, mkpọchị ịta, n'ahụhụ, ịmụ anya arọ nrọ, ụfụ;
• anuri, extrapyramidal aghara, migraine, hemorrhage, mụbara libido;
• ọgbụgbọ, gynecological agba ọbara, paresthesia, vomiting, palpitations, serotonin syndrome, masịrị ọgụ, nsogbu ihi ụra, bruxism, bloating, lethargy, afọ ọsịsa;

• akathisia, eriri afọ agba ọbara, ọbara mgbali elu, akọrọ ọnụ, tachycardia, dyspnea, afọ ntachi, bradycardia, abdominal mgbu, ụkwara;
• ịkụ na nti, ịba ọcha n'anya, orthostatic hypotension, rhinitis, uto nsogbu, belata ọbara mgbali, visual n'ọgba aghara, arrhythmia, ejaculation aghara, Sinusitis, nsogbu nke ulo, galactorrhea, mmekọahụ dysfunction, ebelata agụụ, hyponatraemia;
• arọ ọnwụ, polyuria, mụbara agụụ, ichihịa, erughị eru secretion nke ADH, mgbanwe na ngwá, anụ ọkụ ọkụ, alopecia, ibu ibu, angioneurotic edema, hypokalemia, na-egbu mgbu urination, itching;
• photosensitivity, mụbara sweating, n'ihe ize ndụ nke unan na fractures, urticaria, pyrexia, purpura, myalgias, yawning, arthralgia na ndị ọzọ.

Ikpe nke ọgwụ ovadozu

Drug "citalopram", analogues nke nke na-depụtara n'okpuru ebe a, nwere ike ime ka ndị na-esonụ mgbaàmà nke ovadozu: mara jijiji, ụfụ, vomiting, tachycardia, iro ụra, dilated ụmụ akwụkwọ, bradycardia, hypotonia, ma ọ bụ ọbara mgbali elu, ọgbụgbọ, anụ cyanosis, serotonin syndrome, ùkwù alaka ngọngọ, n'ahụhụ , dizziness, gbasara obi insufficiency, stupor, hyperventilation, sweating, ventricular arrhythmia, atrial arrhythmia, amaghị onwe ya.

ọgwụ interactions

Weere a n'aka pụtara nke ọma na ndị ọzọ ọgwụ. Ya mere, ya co-ochichi na-contraindicated na-esonụ mmadụ:

• Mao inhibitors (nwere ike ịzụlite oké mmetụta, tinyere serotonin syndrome).
• Drugs ogologo oge QT (pụrụ iduga emeghasịkwa nke obi n'afọ iri na ụma, nke n'ikpeazụ ga-adị na-egbu egbu).
• "Pimozide" (ikekwe amụba QT nkeji).

Ọ kwesịkwara kwuru na ngalaba-nlekọta "Citalopram" na ndị ọzọ ọgwụ ọjọọ nwere ike ibelata ọdịdọ mbata. Ke adianade do, a ọgwụ bụghị na-achọsi ike ikpokọta na serotonergic mmadụ, ọgwụ nwere St. Jọn wort wort, anọ anticoagulants, "warfarin", na mmanya, desipramine.

yiri ọgwụ ọjọọ

Gịnị bụ na-ewere analogues nkà mmụta ọgwụ? Nke dị mma? "Citalopram"? Nyocha na-ekwu na ọgwụ ike-anọchi ndị na-esonụ ọgwụ: "Paxil", "cytological" "Pram", "Sedopram", "Oprah", "Umorap", "Siozam", "Tsitalorin" "Cipramil", "Tsitalek" "Tsitalift", "Tsitalon". All ndị a ego kwesịrị inye naanị ahụmahụ dọkịta.

Nnọọ ọtụtụ ndị ọrịa nwere mmasị na ajụjụ nke ihe dị mma: "Citalopram" na "Paxil"? Nyocha ọkachamara na-akọ na mbụ ọgwụ bụ nnọọ irè karịa nke abụọ. Ọ kwesịkwara kwuru na mmetụta na-erukwa na mgbe ngwa nke "Paxil", ndị ọzọ akpọ. Ya mere, ọtụtụ n'ime ndị dọkịta nwere ike ikwu na-eji ya "Citalopram".

Pregnancy na ara

Sị antidepressant ekwesịghị ndinọ ka ụmụ nwaanyị dị ime na nwa ara na nne. The ojiji nke a ọgwụ na-atọ trimester nwere a na-adịghị mma mmetụta na-emetụta akparamàgwà mmadụ ahụ mmepe nke nwa. Ndị na-esonụ imebi ndị na-ekwe omume: cyanosis, akụkụ okuku ume na nsogbu, hypoglycemia, mkpụmkpụ nke ume, vomiting, ụfụ, tremor, okpomọkụ akwusighi, ịma jijiji, ike nri, ahụ mgbakasị, muscle ọbara mgbali elu, ehighi ura, hyperreflexia, mgbe nile na-eti mkpu, lethargy, iro ụra.

Antidepressant "Citalopram": reviews

Mgbe IBS ọgwụ na-kenyere na oké ịkpachara anya. Nke a bụ n'ihi na eziokwu na ya oru ike exacerbate ndị siri ike na otú ọrịa na-arịa.

Gịnị ka ha na-ekwu banyere onyinye na-eji ọkụ ga-eru? Ọtụtụ ndị ọrịa na-agwa banyere ihe ịga nke ọma ọgwụgwọ pụta "Citalopram" ọgwụ ọjọọ. Mgbe anabatarachara nke ọrịa, ha obi ala mma nnọọ anya. Otú ọ dị, ụfọdụ ndị ọrụ na-ekwu na ọgwụgwọ pụta ha chere, ebe ọ bụ na ọgwụ ọjọọ mere ka mmepe nke a ọnụ ọgụgụ nke mmetụta.

Dị ka ndị dọkịta, ha na-arụ ụka na "Citalopram" antidepressant bụ a nnọọ oru oma na irè n'aka, ma naanị na ọnọdụ ụfọdụ ebe ọ bụ anaghị eme ka mmepe nke mmetụta. Ya mere, ọtụtụ ndị dọkịta na-agbalị nye iwu a ọgwụ naanị na oké njọ na na ntakiri doses. Ọ bụrụ na mbụ izu nke ọgwụgwọ dịghị oghom Jeremaya mere e kwuru na, mgbe ahụ, ọgwụgwọ na a ọgwụ anọgide na ụfọdụ na-abawanye na ya dose (ma ọ bụrụ na ọ dị mkpa).