Ọgwụ maka cholesterol: otú irè ha

Ọ bụ mba na nzuzo na ngafe cholesterol n'ime ọbara-emerụ ahụ ike, karịsịa maka gbasara obi na vaskụla usoro. Mgbe umi amalite ngafe edebe ihe karịrị oge na mgbidi ọbara arịa, kpụrụ cholesteric mbadamba nkume ndị e gbochie ije nke ọbara na-eme ka daa ọrịa nke obi na vaskụla abnormalities.

cholesterol umu

Ọ na-ghọtara na ahụ mkpa ụfọdụ cholesterol, na-enweghị ọ gaghị ekwe omume ịdị adị nke mmadụ. Nke a ihe onwunwe bụ akụkụ nke cell akpụkpọ ahụ, ọ dị mkpa maka ịrụ ọrụ nke ụjọ usoro na ndị ọzọ na akụkụ.

Mgbe ọ na-mụụrụ na ngafe content mmewere na-ezo aka na-akpọ ihe ọjọọ cholesterol, nke a na-ejikọta ya na a protein na-etolite a lipoprotein - a kpam kpam ọhụrụ compound. E nwere ihe abụọ na ụdị lipoproteins: elu na ala njupụta. Ya mere, mụbara ọbara etoju nke ala-njupụta lipoprotein na bụ ihe ize ndụ nye ahụ ike.

Na mbụ nkebi nke ọrịa na-atụ aro na-ekwenye a pụrụ iche nri na-eme omume na-emega ahụ. Ma ndị a jikoro bụ ezughị, na mkpa nhicha arịa si cholesterol ọgwụ.

Ọkà mmụta sayensị ogologo e agbalị ike a ọgwụ na ihe n'ụzọ dị irè lowers cholesterol. Otú ọ dị, a zuru okè ngwọta na-adịghị adị, na ọ bụla otu nke ọgwụ, ebelata cholesterol, ọ nwere ma uru na ọghọm.

The ojiji nke statins

Ka ụbọchị, statins - bụ ihe kasị mma na nkà mmụta ọgwụ cholesterol. Ha na-ume na-na akpa ebe na dị elu larịị nke umi. Ọtụtụ mgbe, ndị dọkịta idepụta ọgwụ mee ndị na-esonụ iche iche:

• simvastatin ( "Zocor", "Vasilip");
• atorvastatin ( "Tulip" "Torvakard" "Lipitor" "Atoris" "Liptonorm");
• rosuvastatin ( "Rozukard", "AKORT" "Crestor", "Roxer").

Na obere okwu, statins na-eji, ndị metụtara mbụ ọgbọ nkà mmụta ọgwụ elu cholesterol. Na otu a na-agụnye fluvastatin ( "Lescol"), lovastatin ( "Mevacor" "Holetar") pravastatin. Onye ọ bụla udi nwere ya ọgwụ nrụpụta na ogo nke lipid-ẹsụhọde edinam. Ndị kasị ike statins na-ugbu a na-ewere rosuvastatin na atorvastatin. The kacha gānagide kwa onunu ogwu nke ìgwè nke mbụ bụ 40 mg, nke abụọ - 80 mg.

-Aṅụ ọgwụ maka cholesterol dị mkpa otu ugboro n'ụbọchị nke ehihie. Nke a bụ n'ihi na ha usoro nke edinam. Statins igbochi imeju enzyme na-akpali e guzobere cholesterol. Ma ebe ọ bụ karịa amụba nke cholesterol hụrụ n'abalị, jiri a statin kwesịrị tupu alakpu ụra. Nke a na-achị bụ karịsịa ọdabara mbụ na nke abụọ ọgbọ nke ọgwụ ọjọọ (simvastatin, lovastatin na pravastatin). Modern rosuvastatin na atorvastatin ogologo wepụrụ si ahụ, ya mere, oge nke ha were dịghị mkpa.

E nwere a echiche na ọgwụgwọ maka cholesterol emerụ imeju. Otú ọ dị, nke a a bụ ezi. Na ụfọdụ imeju ọrịa statins-eme ka rụọ ọrụ ndị ọnọdụ nke ngwa (e.g., ọgwụgwọ nke imeju abụba). Ma oké hepatic pathologies iri statins machibidoro n'ihi na elu ịta nke ọcha n'ime ọbara nwere ike na-eduga mmepe nke dị ize ndụ oghom mmetụta: akụrụ odida, na rhabdomyolysis. N'ihi ya, ọ ga-echeta na statin ọgwụ ndị siri ike, na-eme (adịkarịghị) n'akụkụ Jeremaya mere, ha were bụ nanị kwe omume site prescribing mgbe ọma ọgwụ nnyocha.

Uru nke statins

Drugs adịghị nnọọ ibelata ego nke cholesterol, ma belata Ohere nke na-emepe emepe obi na vaskụla nsogbu. Ha nwere nnukwu ogo nchekwa n'oge ruo ogologo oge iji. Mmetụta nke statins abịa mgbe naanị izu abụọ site na mmalite nke iji.

-adịghị emezi emezi

Ọnụnọ nke iwe nke organism (na obere okwu): muscle mgbu, abdominal mgbu, ọgbụgbọ. N'oge ọgwụgwọ ọ bụla ọnwa isii a chọrọ na- imeju ọrụ ule. Na elu doses nwere ike ime ka mmetụta,-eyi ndụ egwu.

The ojiji nke fibrates

Ọgwụ ndị a na-fibric acid emepụta. The ìgwè nke cholesterol ọgwụ ọjọọ na-agụnye fenofibrate, ciprofibrate, bezafibrate, gemfibrozil na clofibrate. Ndị kasị dị irè ọgwụ ọjọọ eme ihe "Traykor", na-ezo na udi nke fenofibrate.

Fibrates statins bụ usụhọde banyere mmetụta na larịị nke ala njupụta lipoprotein na ngụkọta cholesterol, ma mmetụta na elu-njupụta lipoproteins na triglycerides karịrị ha. Site n'iji fibrates na mkpụrụ ndụ ihe nketa larịị bụ a mgbanwe nke cholesterol iga. Ndị a ọgwụ ọjọọ eme ihe maka cholesterol ọgwụ ndị a abụọ akara na-etinyere mgbe statin ọgwụ maka ọgwụgwọ nke hypercholesterolemia. Formulations na-atụ aro mgbe elu-etoju nke triglycerides, dịpụrụ adịpụ gipoalfaholesterinemii.

cholesterol absorption inhibitors

Taa ke Russia, naanị otu ọgwụ ezetimibe otu. Aha nke na nkà mmụta ọgwụ cholesterol - "Ezetrol '. Kenye nwekwara ọgwụ "Inedzhi", nke na-agwakọta Nchikota simvastatin na ezetimibe. The usoro nke ihe nke a mmadụ bụ mebiri nke cholesterol absorption si nsia tract, si otú mbenata ọbara larịị nke a umi.

The uru na-agụnye elu ezetimibe nchekwa nke ọgwụ, n'ihi na ọgwụ adịghị banye n'ime n'ime n'ọbara. Ha nwere ike iwere ndị mmadụ na ọrịa imeju, nakwa dị ka ọrịa ndị na-dị iche iche ihe na-contraindicated na ojiji nke statins. Nke a na-agwọ ya maka cholesterol (reviews na-ekwu banyere ya) nwere ike ji mee ọnụ na a statin, nke na-enye ohere maka enwekwukwa ọgwụgwọ mmetụta.

The ọghọm nke ezetimibe bụ obere oru oma tụnyere statins, nakwa dị ka elu na-eri.

Bile acid sequestrants

Cholesterol na-eme ka amụba nke bile asịd, nke dị mkpa maka ahụ mgbari. Ngwa sequestrants mmemmem nkịtị bile asịd, ha mgbanwe n'ime unyi anaghị agbasa na ogige na excretion. The ahu, ịmara na a enweghị bile asịd, amalite mụta nwa ha intensively si cholesterol, nke mbelata ọdịnaya. Ojiji ọgwụ omume, ndị a ọgwụ ọjọọ eme ihe maka cholesterol na-eji nnọọ adịkarịghị. Ọ aha abụọ ọgwụ ọjọọ nke na otu nke bile acid sequestrant, - "Colestipol" na "Cholestyramine". Otú ọ dị, ha na-agaghị na-emejuputa atumatu nke dị n'ókèala Russia.

The uru nke ndị a ọgwụ ọjọọ eme ihe bụ ha obodo ihe, ha na-adịghị etinye obi gị dum n'ime n'ọbara. The ọghọm gụnyere wetara uto, oge nke mbanye, disturbances absorbability nke abụba na vitamin. The agwọ ọrịa nwere ike ime ka ubara ọbara ọgbụgba.

Ọgwụ "Niacin"

Vitamin eyi ma ọ bụ nicotinic acid, maara nke ọma na ọtụtụ. Agwọ ọrịa "Niacin" - cholesterol na nkà mmụta ọgwụ - dọkịta nwere ike ikwu na-ewere Ibọrọ na elu doses (kwa ụbọchị olu nke aka 4 grams). The ọdịda nke cholesterol na-ewe ebe a di na nwunye nke ụbọchị nke ojiji nke nicotinic acid. Lipid-ẹsụhọde mmetụta nke ọgwụ ọjọọ, "Niacin" bụ n'ụzọ zuru ezu na-amụ. The na-eme nnyocha na-ekwu na vitamin eyi na-egbochi ndị mgbapụ nke abụba na-ebusa asịd, na-enyere iji belata ọjọọ cholesterol.

The uru nke ọgwụ bụ ngwa ngwa results, ekwe omume nke imekotaotuugbo ojiji nke satin. The ọgwụ mma microcirculation, nwere a vasodilatory mmetụta. Enweghị ọgwụ bụ iji nnukwu doses maka lipid-ẹsụhọde mmetụta, ọnụnọ nke mmetụta ndị dị otú ahụ dị ka reddening ihu.

The ojiji nke Omega-3 polyunsaturated ọdụdụ asịd

Otu a na-anọchi anya n'ọtụtụ ebe dị iche iche ndu ifịk nwekwara na ọgwụ ọjọọ. The kasị mara bụ iyak mmanụ na "Omacor." Ụkpụrụ nke ime ihe dabeere na mbenata amụba na imeju triglycerides ma na-amụba ọnụ ọgụgụ nke ndị na-anabata ya aka na ọdụdụ acid ọxịdashọn. N'ihi bụ a ojuju na ala-na-njupụta lipoproteins. The uru nke ọgwụ ọjọọ dị elu nche, concomitant mgbochi arrhythmic edinam.

Low arụmọrụ, eji nanị dị ka ihe adjunct ka ot omume (fibrates na statins) bụ disadvantageous ọgwụ data.