"Ortanol": ihe na-enyere, ntuziaka maka ojiji, n'ezie na

Gịnị bụ ọgwụ "Ortanol"? Site na ihe na-enyere ndị na nkà mmụta ọgwụ? The azịza ajụjụ ndị a nwere ike ịchọta n'okpuru. Ke adianade do, anyị ugbu price nke sị ngwaahịa, ya contraindications, analogs na ntọhapụ ụdị.

Mbukota ọgwụ, mejupụtara, nkọwa, ụdị

Nkwadebe "Ortanol" e mere n'ụdị ike capsules size № № 1 ma ọ bụ 2. Nke a pụtara nwere a na-acha ọcha na agba, nakwa dị ka ihe e dere «Ome 20» ma ọ bụ «Ome 40 '(dabere na onunu ogwu). Content ọgwụ capsules-anọchi anya odo pellets.

Ahụ na-agụnye ọgwụ "Ortanol"? Nyocha na-atụ aro na ntoala umi a na-ewere ọgwụ omeprazole. Ọzọkwa ya nwere inyeaka mmiri dị ka croscarmellose sodium, ala nnọchianya giproloza, lactose anhydrous, microcrystalline cellulose, hypromellose phthalate, povidone, polysorbate 80, talc na dibutyl sebacate.

The mejupụtara nke Capsule shei bụ: propylene glycol, hypromellose, butanol, carrageenan, ethanol anhydrous, shellac, potassium chloride, anhydrous isopropanol, titanium dioxide, ink e dere na mmiri.

Na ire agwọ ọrịa "Ortanol" (Capsule) abatakwa ọnya, packaged n'ime katọn.

Pharmacological edinam nke ọgwụ

Gịnị bụ a "Ortanol" (site na ihe na-enyere nke a na nkà mmụta ọgwụ, ị ga-amụta n'okpuru)? Dị ka ntụziaka, ọgwụ bụ a proton mgbapụta inhibitor. Ọ na-ebelata acid mmepụta, ie, slows ala ọrụ nke K + -H + -ATPase na afo, ma ọ bụ kama na ya parietal mkpụrụ ndụ. Ọzọkwa Ọ nkanka ikpeazụ ogbo nke gastric acid secretion.

Drug "Ortanol", ego nke nke na-depụtara n'okpuru ebe, bụ a prodrug. Ngwá ọrụ a na-arụ ọrụ na acidic na-ajụ nke tubules (secretory) parietal mkpụrụ ndụ. Ke adianade do, ọ na-ebelata kpaliri na basal secretion n'agbanyeghị ọdịdị nke mkpali.

Antisecretory Njirimara nke agwọ ọrịa ime n'ime akpa 60 nkeji (kacha mgbe 2 awa). Mgbochi nke 50% nke kacha secretion na-aga n'ihu ofụri usen.

A otu dose nke ọgwụ na-enye irè na ngwa ngwa suppression nke ehihie na abalị gastric secretion. Ya kacha ya eruo ihe ndị 4th ụbọchị nke ọgwụgwọ na-akwụsị mgbe ụbọchị atọ mgbe ọgwụgwọ.

Kinetic Njirimara nke ọgwụ ọjọọ

Mgbe e ndị "Ortanol" nkwadebe ya oji elu absorption. Ọnụ ọgụgụ kasị elu ịta nke omeprazole n'ime ọbara hụrụ mgbe 0.5-3 awa. The zuru bioavailability nke ọgwụ bụ 30-40%, na agwọ ọrịa metụtara plasma-edozi - 95%.

Omeprazole metabolism na imeju na-etolite isii pharmacologically-adịghị ejekwa ozi emepụta.

The ọkara ndụ ọgwụ oge bụ 0.5-1 awa. Mmepụta ya dị ka nkwekọrịta site akụrụ (70-76%) na ọnụ na bile (18-24%).

Ndị na-adịghị ala ala imeju ọrịa bioavailability nke ọgwụ na-budata ụba, na plasma ọkara ndụ esịmde 3 awa.

Na ọrịa na-adịghị ala ala ọrịa akụrụ excretion slows ala. Na nke a emee ke hà ka ndị gụnyere ya ná CC.

Agwọ ọrịa "Ortanol": ihe na-enyere?

Weere a ọgwụ gosiri maka ndị na-esonụ ọrịa:

• reflux esophagitis;
• eriri afọ ọnyá afọ ọrịa ozu (gụnyere nlọghachi azụ mgbochi);
• hypersecretory ekwu (nchegbu ọnyá nke eriri afọ, Zollinger-Ellison syndrome, systemic mastocytosis, polyendocrine adenomatosis);
• nditre Helicobacter pylori oria ọrịa na ọnyá ọrịa nke digestive tract (na Nchikota ọgwụ);

• ọgwụgwọ na mgbochi nke eriri afọ mucosal mmebi akụkụ nke na-kpatara NSAID (mucosal ozize, dyspepsia, peptic ọnyá afọ).

Bans na-eji ọgwụ ọjọọ

Gịnị bụ contraindications ọgwụ nwere "Ortanol" (site na ihe na-eme ka ngwá ọrụ a, anyị gwara n'elu)? Dị ka ntụziaka, na-ewere ọgwụ ike ga-eji mgbe:

• lactation;
• na nwata;
• hypersensitivity ọgwụ umi.

Na pụrụ iche ịkpachara anya na-ewere ọgwụ ọjọọ ọgwụ maka gbasara akụrụ na imeju na ọdịda.

Drug "Ortanol": okwu

A ọgwụ na-kenyere naanị n'ime. Ọ na-e tupu a nri (na-emekarị ke usenubọk tupu nri ụtụtụ).

The Capsule na ọgwụ a na-loro na dum na mmiri. Na ikpe, ma ọ bụrụ na onye ọrịa bụ na-enweghị ike iji ọgwụ kpamkpam, na ya nwere ike etisasịwo ke a obere ego bụ nnọọ acidic mmiri mmiri.

The onunu ogwu nke ọgwụ na-adabere na-egosi.

Mgbe onya 12 duodenal ọnyá afọ agwọ ọrịa amịnye 20 mg otu ugboro n'ụbọchị izu abụọ. Ke edinam na mgbe mbụ afọ zuru ezu n'ichihịa adịghị ime, re-họpụtara izu abụọ ọgwụ.

Mgbe ọnyá afọ ọrịa eguzogide ọgwụgwọ, ngwá ọrụ a na-atụ aro na-na a dose nke 40 mg otu ugboro n'ụbọchị. N'ezie nke ọgwụ na a ọgwụ nwere ike ike ịgbatị na izu anọ.

Ọgwụ "Ortanol" na-egosi nke e depụtara n'elu, ọnyá ọnya nke afo na-ewere 20 mg ugboro kwa ụbọchị maka izu anọ. Ọ bụrụ na n'ichihịa adịghị ime mgbe gafere afọ, re-họpụtara izu anọ ọgwụ. Na gastric ọnyá afọ, eguzogide ọgwụ ọgwụgwọ, ọgwụ na-atụ aro ka na-ahụ a dose of 40 mg otu ugboro n'ụbọchị (ọnụego ruo asatọ izu).

Nditre Helicobacter pylori a rụrụ na a Nchikota ọgwụ. Na nke a, na agwọ ọrịa amịnye 20 mg ugboro abụọ n'ụbọchị tupu nri (izu abụọ) na Nchikota na antibacterial mmadụ.

Mgbe reflux esophagitis ọgwụ na-atụ aro iji ke ichekwa 20 mg (otu ugboro) maka izu anọ. Ọ bụrụ na a Usoro ọgwụ a anaghị eme ka mezue ọgwụgwọ ahụ, onye ọrịa na-kenyere a abụọ N'ezie (izu anọ). Na oké reflux esophagitis ọgwụgwọ na ngwá ọrụ a gbasaa ruo asatọ izu.

Mgbe hypersecretory steeti a na-ewere a na nkà mmụta ọgwụ nrekasi obi ndinọ n'otu n'otu. The na-atụ aro na-amalite usoro onunu ogwu n'ihi na ndị okenye bụ 60 mg (otu ugboro), na kacha - 120 mg.

N'ịhọpụta ọgwụ karịa 80 mg kwa ụbọchị, ọ na-ekewa n'ime ọtụtụ nkebi.

Mgbe eriri afọ mucosa ngwa mmebi, nke na-kpatara NSAID, nakwa dị ka ihe mgbochi nke Capsule "Ortanol" nwere ike ikwu na ojiji nke a dose of 20 mg kwa ụbọchị, tupu nri ụtụtụ (maka dum oge nke NSAID ọgwụ).

N'ihi na ndị agadi ndị na ndị mmadụ na oké ọrịa imeju kacha kwa ụbọchị dose bụ 20 mg.

N'ihi na ọrịa na mkpọchị ọrụ nke akụrụ onunu ogwu ukpụhọde a chọrọ.

phenomena n'akụkụ

Gịnị Jeremaya mere ifọnke eme ọgwụ ọjọọ, "Ortanol"? Nyocha sị mmetụta:

• isi ọwụwa, bịara ikiri ọhụụ, dizziness, erythema multiforme, paresthesia;
• iro ụra, ọgbụgbọ, uto nsogbu, afọ ọsịsa, ehighi ura, bloating;
• n'ahụhụ, akọrọ ọnụ, ịda mbà n'obi, ọrịa, reversible uche mgbasasị;
• encephalopathy, gynecomastia, ịba ọcha n'anya, elu edema, vomiting, na photosensitivity;
• abdominal mgbu, thrombocytopenia, afọ ntachi, pancytopenia, mmụba nke alkaline phosphatase ọrụ na imeju na transaminase;
• itchy anụ ahụ, mkpọchị imeju ọrụ, muscle adịghị ike, e guzobere gastric glandular cysts;
• alopecia, eosinophilia, ubara sweating, bronchospasm, agranulocytosis, angioedema;
• leukopenia, myalgia, fever, arthralgia, anaphylactoid Jeremaya mere, urticaria, interstitial nephritis.

Mmetụta na-erukwa na ngwa nke akuko mmadụ dị nwayọọ ma na-akwụsị akwụsị ke uwa.

ikpe nke ovadozu

Mgbe na-ewere ọgwụ maka nrekasi obi na a ọrịa na-esonụ mgbaàmà nwere ike ime: isi ọwụwa, akọrọ ọnụ, tachycardia, iro ụra, ọgbụgbọ, bịara ikiri ọhụụ, vomiting, mgbagwoju anya, ubara sweating.

N'okpuru ọnọdụ ndị dị otú, symptomatic ọgwụ.

ọgwụ interactions

Ọnụ na mbanye omeprazole ubara ọkara ndụ na ubara ịta "Diazepam", "warfarin", "phenytoin", nakwa dị ka ndị ọzọ ọgwụ ọjọọ eme ihe na-metabolized na imeju na isoenzyme CYP2C19.

Absorption n'aka ike na-achị obodo, na bioavailability nke kpebisiri ike site acidity nke gastric ihe ọṅụṅụ (e.g., "Itraconazole" "ketoconazole" esters nke ampicillin "cyanocobalamin" na ígwè salts).

The bioavailability nke digoxin mgbe co-ndinọ na omeprazole bụ ubara site na 10%.

E lee ya anya ọgwụ enhances inhibitory mmetụta na usoro ndị ọzọ hematopoietic ọgwụ ọjọọ.

Ọ dịghị clinically ịrịba ọgwụ mmekọrịta antacid ọgwụ ọjọọ, caffeine, "theophylline", "Quinidine", "propranolol", ethanol, lidocaine na "metoprolol" na-agaghị.

kpọmkwem na-atụ aro

malignancy ga-ekwe tupu ịmalite ọgwụgwọ na omeprazole. Nke a bụ n'ihi na eziokwu na nke a usoro ọgwụ pụrụ ikpuchi ihe mgbaàmà na-egbu oge na-arịa na nkwupụta.

Ugbu a, e nweghị data na mmetụta nke ego na a mmadụ na-ike ịchịkwa usoro na ụgbọala ugbo ala.

Na-eri na analogues

Ego ole ka a mgbochi ọnyá afọ ọgwụ, dị ka "Ortanol"? The price nke a ọgwụ bụ banyere 100-115 rubles. N'ihi na ọtụtụ na-eji ọkụ, na-eri nke a bụ ihe dị mma.

Gịnị nwere ike dochie ọgwụ "Ortanol"? Analogs a nkwadebe na-ọkọnọ n'ụdị "omez", "Loseprazol", "Gaseka", "Omelika", "omeprazole".

Nyocha

Nyocha nke capsules "Ortanol" bụ mma ka ukwuu. Ọrịa na-ekwu na ọgwụ dị irè antiulcer n'ụlọnga. Ọ ngwa ngwa eliminates nrekasi obi na mmetụta nke arọ na-ere ọkụ nke afo.

Ọkachamara na-ekwu na ọgwụ na ajụjụ nwere mmetụta dị mma n'ebe N'ezie nke ọrịa nke digestive tract naanị ma ọ bụrụ na ya n'ikuku, a họpụtara site na a gastroenterologist. Dọkịta na-akọ na ha onwe ha na-a ọgwụ na-aju, dị ka ọ nwere ike mmetụta.

E nwekwara a nke oma n'akụkụ nke a ọgwụ na-agụnye ya nnweta na ala na-eri.