APTT welitere: Ntak emi ẹwọrọde? Dịkwuo APTT n'oge ime

APTT (ọrụ ele mmadụ anya n'ihu thromboplastin oge) - nke a bụ a dị nnọọ mkpa egosi ọbara clotting, nke-enye gị ohere ikpebi ihe ize ndụ egbochi mkpụkọ nke ọbara ma ọ bụ omume nke ọbara ọgbụgba. N'ụzọ ziri ezi adabere na-arụ ọrụ nke coagulation usoro, i nwere ike ikpebi otú oké ọrịa bụ, na-ahọrọ ọgwụgwọ n'ụzọ ziri ezi. Ka anyị kwuo banyere ya.

Olee otú bụ APTT ule?

Nyochara on ọnụego nke ọbara clotting enyere mata systemic abnormalities na-emekarị na-egosi na e nwere imebi nke quantitative na qualitative egosi nke ọbara.

Dị otú ahụ analysis a rụrụ na a kpọmkwem ụkpụrụ. Akpa, ihe-atụle, agbakwunyere na tube nwere anticoagulant nkịtị nke calcium ion, n'ihi na nke ọbara adịghị clot. Emejuputa atumatu oru site centrifugation ikewara plasma si platelet ndị ọzọ ọcha. Mgbe nke ahụ gasịrị, ule tube e kwukwara phospholipids, calcium chloride na ihe activator. Malite na-amata oge na nke a ọbara clot a kpụrụ.

Phospholipids rụọ ọrụ extrinsic ụzọ nke coagulation, na calcium chloride bụ ihe dị mkpa umi na usoro nke coagulation. Dị otú ahụ analysis anaghị n'ụzọ zuru ezu inwale usoro nke thrombus guzobere, ma na-enyere aka iji mata abnormalities na ọnụego, na mgbe ahụ anya n'ihi na ndị na-akpata nke a onu.

Mgbe ụfọdụ, ọ na-enyo na APTT ụba ma ọ bụ mgbada n'usoro. Nke a na-arụtụ aka na ẹdude nsogbu ke idem.

norm

The egosi tụrụ na sekọnd na ike ịdị iche iche ruru ike, afọ nke onye ọrịa ahụ na ọgwụgwọ. APTT Nkịtị okenye mmadụ bụ site 28 ruo 40 sekọnd. A mụrụ ọhụrụ, nke a na ọnụ ọgụgụ dị elu nke 1-3 sekọnd.

Elu ọbara aPTT na-chọpụtara mgbe ọ bụla clotting akpata na-ebelata ma ọ bụ mụbara site karịa 30%. Belata ọnụego mgbe egosi hypercoagulability.

Mkpebi siri ike nke APTT na ndị okenye na ụmụaka na-ẹkenịmde iji chọpụta ihe na-akpata ogbenye egbochi mkpụkọ nke ọbara, nakwa dị ka inwale irè nke ọgwụgwọ na anticoagulants.

Mere amụba APTT

Ọtụtụ nnọọ iwe mgbe ha na-achọpụta na APTT ụba. Gịnị ka ọ pụtara? Nke a na-eme mgbe e nwere ihe ize ndụ nke ọbara ọgbụgba. Ihe mere nwere ike ịbụ:

1. Ezughi oke ego nke vitamin K ke idem. Nke a na-arụtụ aka nsogbu na digestive usoro, n'ihi na nke a vitamin na-akwalite njikọ nke nsia bacteria. Ọ na-dị oké mkpa maka kwesịrị ịrụ ọrụ niile clotting ihe. Ya erughi emee ruru dysbiosis, na eme ihe ike ike na-eri, na-akpata ogologo oge ọgwụgwọ na ọgwụ nje.
2. Genetic abnormalities na na-metụtara ndị mebiri nke qualitative na quantitative kwa ọbara. Na nke a, index APTT ụba nke ukwuu.
3. Ọbara hemorrhage, nnukwu leukemia, DIC.
4. Hemophilia ụdị A, B, C.
5. Ọnụnọ nke-alụso ọrịa ọgụ na ọbara megide ịkpakọba ihe na lupus anticoagulant.
6. Ezighị ezi nkwadebe maka analysis, na mberede ingress nke heparin na sample.

Mụbara APTT, a nwekwara ike nwa ịbụ n'ihi na ihe ndị a.

APTT n'oge ime

N'oge ime, rụọ ọrụ ele mmadụ anya n'ihu thromboplastin oge na-amalite ịgbanwe. Ọ bụrụ na ọnụego maka nkezi onye bụ n'etiti 28 40 sekọnd, na nwanyi di ime na ọ bụ 17-20 sekọnd. Nke a pụtara na ọ na-ebelata. Mgbanwe ndị dị otú akpasu ndị na-esonụ ihe:

• Na oge a tara akpụ na a nwanyi ahu, onye ọzọ na utero-placental mgbasa. Plasenta mejupụtara a plurality arịa. Ọ bụrụgodị na ọ na-ewe ebe a obere detachment, ọbara na ọnwụ nwere ike ịbụ n'ihe. Abụkarị detachment emee ya ruru na ụba eriri akpa nwa ụda.
• N'oge ọmụmụ nwaanyị na-emekarị na-efunari ruo 400 ml ọbara. Nke a na-eme ngwa ngwa, na coagulation usoro ga-adị njikere maka ndị dị otú ahụ a siri ike na ọnwụ nke ọbara, ka egbochi mkpụkọ na-amalite na-kpụrụ ngwa ngwa iji gbochie ọbara na ọnwụ.

Mere APTT elu na ime?

APTT na-ụba ma ọ bụrụ na ndị clotting oge bụ karịa 40 sekọnd. Nke a na-ebelata ikike egbochi mkpụkọ nke ọbara na-etolite, na-akpata ihe ize ndụ nke elu ọbara na ọnwụ.

Nọmalị APTT ụba ma ọ bụrụ na nwaanyị dị ime na-ewere ọgwụ nje, heparin, aspirin na thrombolytic ọgwụ ọjọọ. Tupu na-anwale, o kwesịrị igosi ha dibịa.

The abawanye na APTT egosi a ọnụ ke ọbara nwere ikike clot, ọ pụtara na ndị na-esonụ-enweghị nchịkwa na ọnọdụ:

• Ọrịa imeju yi owụt hepatic ọdịda, tinyere na imeju. Na nke a, e nwere a mebiri nke njikọ nke clotting ihe na ọbara.
• Enweghị vitamin na K, pụtara megide a ndabere nke dysbiosis ke gootu, nakwa dị ka n'ihi na-ezighị ezi nri.
• Arịa ọrịa kansa ọbara.
• Hemophilia ụdị A, B, C. Nke a bụ a butere n'aka ọrịa ji a congenital erughi nke clotting ihe, na-ewetakarị a n'amaghi ọbara ọgbụgba ime.
• Von Willebrand oria.

ọgwụgwụ

Analysis na APTT bụchaghị rụrụ n'ihu forthcoming ọrụ ịchọpụta otú ngwa ngwa ọbara nwere ike clot. A na-abawanye ma ọ bụ ọnụ si norm na-egosi ihe dị iche iche pathologies. Iji zere ihe ize ndụ nke ọbara ọgbụgba, na-emeso ya.