"Indapamide": ogbo. "Indapamide": reviews nke dọkịta

Gịnị bụ a ọgwụ ọjọọ, "Indapamide"? Analogs nke ngwá ọrụ, ya na ndu, na mmetụta na-egosi maka ojiji ga-ọkọnọ n'okpuru. Ke adianade do, ke ibuotikọ emi ị ga-amụta ma ma ọ bụ a ọgwụ contraindications, ihe na-eme bụrụ na ndị ovadozu dị ka o kwesịrị, ma ọ bụ omume na ikpokọta na ọgwụ ọjọọ ndị ọzọ, na ihe ha na-eche banyere ya ọkachamara.

The mejupụtara nke ọgwụ na ya ntọhapụ ụdị

Olee ụdị a ọgwụ bụ maka ire? The ahịa ọgwụ nwere ike hụrụ naanị n'ụdị biconvex mbadamba ntekwasa na-acha ọcha film mkpuchi.

Gịnị bụ n'ọrụ mgwa na-agụnye a agwọ ọrịa "Indapamide"? Analogs nke a gị n'ụlọnga (ọtụtụ n'ime ha) na nkwadebe onwe ya nwere ifịk ifịk mmiri dị ka indapamide. Na-akwanyere inyeaka bekee, mbadamba nkume na-agụnye ndị na-esonụ components: lactose monohydrate, crospovidone, povidone K-30, magnesium stearate, talc na sodium lauryl sulfate.

The pharmacological edinam nke ọgwụ

Gịnị Njirimara nke ọgwụ ọjọọ, "Indapamide", ego nke nke na-egosi na njedebe nke isiokwu a? Nke a na ọgwụ bụ nke antihypertensive n'ụlọnga. Na ọzọ okwu, ọ bụ a mamịrị na vasodilator.

Dị ka ha na pharmacological Njirimara, ọgwụ bụ nnọọ nso na thiazide diuretics na natara mebiri reabsorption nke sodium salts, nke na-emi odude ke cortical nke nke akaghị nke Henle. Ọ bụ ike na-amụba na evolushọn nke chlorine, magnesium ion, sodium na potassium na mmamịrị.

Mere nye iwu ọgwụ "Indapamide"? Analogs nke ngwá ọrụ na ya, si agwọ ọrịa bụ ike nke na igbochi "nwayọọ" calcium ọwa nhọrọ n'ụzọ, dịkwuo ekwedo nke arịa mgbidi na Lower ngụkọta vaskụla eguzogide (elu).

Ikweta na ọgwụ na-ebelata ihe hypertrophy nke obi, ma ọ bụ kama ya ekpe ventricle. Ọ dịghị ihe mmetụta na ego nke lipids na ọbara, nakwa dị ka carbohydrate metabolism, gụnyere ndị mmadụ na ọrịa ndị dị ka ọrịa shuga.

Sị na agwọ ọrịa ebelata uche nke vaskụla mgbidi angiotensin II na nọrepinefrini, anụ ma na-ebelata mmepụta nke oxygen free radicals, akpali njikọ nke prostaglandin E2.

Na etinye ọgwụ hypotensive edinam amalite site na njedebe nke 1st izu nke ọgwụ. Ke idaha ọ na-echekwara maka 25 awa (mgbe a otu onu)

Pharmacokinetics nke ọgwụ

Ebe etinye obi gị dum ọgwụ "Indapamide"? Ntuziaka, kwuru ndị ọkachamara na-ekwu na mgbe na-ewere ọgwụ ọjọọ n'ime ya fọrọ nke nta kpamkpam na-ntabi-etinye obi gị dum na eriri afọ tract. Ka pharmacists ịnọgide na-enwe ya bioavailability bụ 93%. Imekotaotuugbo n'ikuku nke nri slows absorption ọnụego nke a obere, ma adịghị emetụta olu nke dose etinye obi gị dum bụ nke ugbu a mmewere.

The kacha ịta nke nọ n'ọrụ mgwa na plasma a na-enweta mgbe banyere 2 awa mgbe ochichi nke otu mbadamba. The ọkara ndụ nke ọgwụ bụ 14-25 awa. Communication na ọbara na-edozi - banyere 79%.

Nkwadebe a ọma na-aga site na ọbara-anụ mgbochi (gụnyere placental). Ọ na-odụk mmiri ara.

The metabolism nke ọgwụ na imeju. Ọ na-ghọtara akụrụ (dị ka metabolites) ke ichekwa 60-80%, na 20% - by eriri afọ.

Egosi maka ojiji nke agwọ ọrịa

Mgbe ụfọdụ, ọrịa na-kenyere ọgwụ "Indapamide"? Egosi maka ojiji nke ngwá ọrụ a na-agụnye naanị otu enweghị nchịkwa ọnọdụ nke onye ọrịa. Ọ ọbara mgbali. Ọzọkwa, agwọ ọrịa nwere ike na-kenyere na sodium na mmiri njigide ke idem. A, nke a ọnọdụ mgbe hụrụ na ọrịa na-adịghị ala ala obi ọdịda.

Contraindications ojiji nke ọgwụ

Ugbu a na ị maara ihe a pụtara ọgwụ ọjọọ, "Indapamide" (egosi maka ojiji nke ego e adade dị n'elu). Otú ọ dị, ọ ga-kwuru na nke a ọgwụ e nwere contraindications. Ndị a gụnyere ndị na-esonụ ihe:

• lactose anabataghi ọrịa ahụ;
• n'oge ime;
• galactosemia;
• hypokalemia;
• syndrome ọrịa mmiri galactose ma ọ bụ glucose;
• lactation;
• imekotaotuugbo ngwa nke ọgwụ, bụ ndị nwere ike ịgbatị nkeji QT;
• oké gbasara akụrụ odida (ma ọ bụ anuria nzọụkwụ);
• afọ a onye n'okpuru afọ 18 (nchekwa na nrụpụta ọrụ na ọgwụgwọ nke ụmụ bụghị a guzosie ike);
• oké hepatic, gụnyere encephalopathy, ọdịda;
• hypersensitivity ọgwụ na ndị ọzọ na sulfonamide emepụta.

Nlezianya ojiji nke agwọ ọrịa

Ọtụtụ ndị na-eche ma na-azụ "Indapamide" mkpa a ọgwụ ọgwụ? N'eziokwu, tupu iji nke ọ bụla ọgwụ na-atụ aro ka ịkpọ onye dọkịta - a ọkachamara nanị mgbe nnyocha na na ndabere nke ule results nwere ike iru a eru ọgwụgwọ Usoro. Banyere anyị ikpe, anyị mara na atụle ngwá ọrụ na oké ịkpachara anya kenyere ndị na-arịa ọrịa shuga, gout, nakwa dị ka ndị ọrịa bụ onye-asọ sulfonamide emepụta.

Ke adianade do, ọgwụ kwesịrị iwere nke ọma na-anaghị ekwe nke imeju, akụrụ na mmiri-electrolyte ahaghị nhata.

N'oge ọgwụ dọkịta ga mgbe niile nyochaa larịị nke electrolytes n'ime ọbara nke a ọrịa (potassium, sodium, calcium).

Drug "Indapamide": ntuziaka maka ojiji, n'ezie na ọkachamara

Dị ka mmasị ntuziaka, ọgwụ ga-a ọnụ, n'agbanyeghị nri oriri. The mbadamba kwesịrị iwere na a zuru ezu ego nke dị ọcha mmiri.

Olee otú ga-ewere "Indapamide"? Dị ka ọkachamara, a ọgwụ na-mma etinye obi gị dum na eriri afọ tract na n'isi ụtụtụ. Ya mere, ọ na-atụ aro na-na n'oge a nke ụbọchị.

Ọnụọgụ ọgwụ bụ 2,5 mg (i.e., otu mbadamba) kwa ụbọchị. Ọ bụrụ na mgbe 4-8 izu nke ọrịa, ezi mmetụta na a ruru, olu nke ọgwụ adịghị mkpa ntọt (ọ bụ ezie na mgbe dọkịta ime nke). Nke a bụ eziokwu bụ n'ihi na eziokwu na na elu doses enwekwu ihe ize ndụ nke mmetụta. Kama, usoro ọgwụ dị mkpa na-agụnye ndị ọzọ antihypertensive gị n'ụlọnga na-adịghị a mamịrị.

Olee otú ga-ewere "Indapamide" na nke a? Mgbe concomitant ochichi nke abụọ ọgwụ ọjọọ na-atụle site anyị ọgwụ dose-anọgide na-agbanweghi agbanwe, i.e. 2,5 mg kwa ụbọchị (n'isi ụtụtụ).

Ikpe nke ovadozu: Mgbaàmà, Ọgwụgwọ

Gịnị na-eme ma ọ bụrụ na ị na-a ọnụ ọgụgụ buru ibu nke "Indapamide" ọgwụ ọjọọ? Nyocha nke dọkịta na-ekwu na dị otú ahụ ikpe onye ọrịa nwere ọgbụgbọ, n'adịghị ike na vomiting. Ke adianade do, ọrịa bụ na-esogbu na mmiri na electrolyte itule na-arụ ọrụ nke digestive tract. Mgbe ụfọdụ, ọrịa nwere a siri ike gụnyere ya ná ọbara mgbali na akụkụ okuku ume na ịda mbà n'obi. Na ọrịa na imeju nke imeju nwere ike ịbụ hepatic amaghị onwe ya.

Olee otú na-emeso? Bụrụ na nke ovadozu, ọrịa ga-asa na afo, na-agbazi mmiri na electrolyte itule, ma na-eme symptomatic ọgwụ.

Oghom mmetụta mgbe na-anata agwọ ọrịa

oghom Jeremaya mere mgbe na-ewere "Indapamide" ọgwụ e nwere ịdị? Mmetụta nke a ọgwụ bụ. N'ebe a, ha na-now.

• Digestive usoro: gastralgia, ọgbụgbọ, abdominal mgbu, vomiting, anorexia, afọ ntachi, akọrọ ọnụ, pancreatitis, afọ ọsịsa, hepatic encephalopathy.
• Akụkụ okuku ume na usoro: Sinusitis, ụkwara, rhinitis na pharyngitis.
• Ụjọ usoro: ehighi ura, ike ọgwụgwụ, muscle cramps, ịma jijiji, adịghị ike, nchegbu, isi ọwụwa, ike ọgwụgwụ, vertigo, dizziness, ịda mbà n'obi, iro ụra, ahụ mgbakasị, malaise na erughị ala.
• Urinary System: nocturia, ibute ọrịa ugboro ugboro, na polyuria.
• Obi na ọbara arịa: arrhythmia, orthostatic hypotension, obi ọnụego na ECG mgbanwe (ie, hypokalemia).
• Allergy: aṅụ, ihe ọkụ ọkụ, itching na hemorrhagic vasculitis.
• hemopoietic usoro: thrombocytopenia, hemolytic anaemia, leukopenia, ụmị ọkpụkpụ aplasia, na agranulocytosis.
• Laboratory Nchoputa: glycosuria, hyperuricemia, mụbara urea nitrogen n'ime ọbara plasma, hyperglycemia, hypercreatininemia, hypokalemia, hypercalcemia, hyponatremia na hyposalemia.
• Ndị ọzọ: exacerbation nke systemic lupus erythematosus.

Mmekọrịta ndị ọzọ ọgwụ ọjọọ eme ihe

Drug "Indapamide", onye edinam iji na ẹsụhọde nsogbu, ọ na-adịghị na-atụ aro na-na njikọ na gbasara obi glycosides, dị ka ọ na-enwekwu ohere digitalis igbu egbu. Ọ bụrụ na ị na-eji ngwá ọrụ a na calcium preparations na metformin, onye ọrịa nwere ike ịzụlite hypercalcemia na aggravated lactic acidosis.

N'otu oge ochichi nke agwọ ọrịa na corticosteroids, NSAIDs, sympathomimetics na tetrakozaktidom belata hypotensive mmetụta nke mbụ. Banyere n'aka "baclofen", o, on Kama nke ahụ, o sie ike.

The Nchikota nke ọgwụ na potassium-ịhapụ diuretics n'ụzọ dị irè a obere ọnụ ọgụgụ ndị ọrịa. Otú ọ dị, ọ dịghị achị si ekwe omume nke hyper- ma ọ bụ hypokalemia, karịsịa na ọrịa na gbasara akụrụ insufficiency na-arịa ọrịa shuga.

Ace inhibitors nwere ike dịkwuo ize ndụ nke hypotension na nnukwu gbasara akụrụ odida.

Nwere ike akpaghasị akụrụ na-eji iodinated mmadụ na elu doses.

Neuroleptics na antidepressants imipraminovye eme ka ụba hypotensive edinam na n'ihe ize ndụ nke orthostatic hypotension.

Special ntuziaka maka ojiji "Indapamide" ọgwụ

Na ihe ikpe kwesịrị nyochaa ọrịa ọbara na foto a mgbe nhọpụta nke "Indapamide" ọgwụ ọjọọ? Nyocha nke dọkịta na-ekwu na a ọgwụ nwere ike ịgbanwe ego nke creatinine na potassium ion na ndị ọrịa na-laxatives, gbasara obi glycosides, nakwa dị ka na ndị mmadụ n'otu n'otu okenye karịrị afọ 60.

Mgbe na-eji nke a mara mọbụrụ na-atụ aro ọkà n'usoro nyochaa ịta nke sodium ion, potassium na magnesium, n'ime ọbara plasma, ebe ọ bụ na ọrịa nwere ike ịzụlite electrolyte disturbances. Ọ dịkwa mkpa iji nyochaa onye Onyenwe anyị +, ịta nke uric acid, glucose, na mmapụta nitrogen.

Special akara ga-n'okpuru ọrịa na imeju imeju (na ike edema ma ọ bụ ascites), nakwa dị ka obi odida na ischemic ọrịa obi.

Elu-ize ndụ na-agụnye ọrịa na ihe mụbara QT nkeji na ihe ngwá (nwere ike congenital ma ọ bụ ịzụlite na ndabere nke ọ bụla daa ọrịa).

The mbụ n'ihe nke potassium ion ịta n'ime ọbara nke onye ọrịa na-atụ aro na nke mbụ izu nke ọgwụgwọ.

Uche pụrụ iche na-atụ aro ka e nye ọrịa na-arịa ọrịa shuga. Karịsịa, ọ dị mkpa inyocha larịị nke glucose dị n'ọbara, karịsịa ma ọ bụrụ na onye chọpụtara na hypokalemia.

Ọrịa na-ewere nke a ọgwụ, ị kwesịrị ị na chefuo maka ọnwụ nke mmiri site na-eri ọtụtụ oke mmiri a ụbọchị. Ọzọkwa, ná mmalite nke ọrịa, ọ dị mkpa inyocha akụrụ ọrụ.

Anyị apụghị ikwu na ọgwụ "Indapamide", analogues nke na-egosi n'okpuru, nwere ike inye a mma n'ihi n'oge doping akara.

Ọrịa na hyponatremia, na ọbara mgbali elu, maka 3 ụbọchị tupu ojiji nke angiotensin n'ịtụgharị enzyme inhibitors, diuretics ga-kwụsịrị. Ọgwụgwọ nwere ike maliteghachiri mgbe e mesịrị.

N'ịhọpụta ọgwụ "Indapamide" ọkachamara kwesịrị maara na a sulfonamide emepụta nwere ike mfe ime ọrịa ndị dị ka systemic lupus erythematosus.

Ka ụbọchị, na nchekwa na nrụpụta ọrụ nke ọgwụ na ọgwụgwọ nke eto eto ụmụ na-eto eto ka e guzobere.

N'oge ụfọdụ, o kwere omume na onye Jeremaya mere na na-metụtara mgbanwe ọbara mgbali. A, nke a mere ná mmalite nke ọrịa, dị ka nke ọma dị ka iji ọzọ antihypertensive ọgwụ ọjọọ. N'ihi ya, nke a nwere ike ibelata ike ịchịkwa igwe na-arụ ọrụ na ndị ọzọ usoro nke na-achọ pụrụ iche.

Nyocha ọkachamara na ndị ọrịa na ọgwụ

Ugbu a, ị mara na bụ ọgwụ "Indapamide". Nyocha, na price nke ọgwụ ga-ọkọnọ now.

Ọkachamara na-ekwu na nkà mmụta ọgwụ si anagide ọma na ọrụ. Nke a n'ụzọ dị irè na lowers ọbara mgbali, na-eme dị ka a mamịrị.

Nyocha nkwadebe "Indapamide" na-egosi na mgbe ngwa nke ekpe ventricular hypertrophy na-ebelata, na ya antihypertensive mmetụta na-apụta ìhè ọbụna ndị ndị ọrịa hemodialysis.

Ma ihe ndị na-ezighị ezi kwuru, sị n'aka, ọtụtụ ugboro karịa bụghị ha na-metụtara onye ahụ nke a ọnụ ọgụgụ buru ibu nke oghom Jeremaya mere. Otú ọ dị, ọ ga-kwuru na ndị dị otú mmetụta na-hụrụ naanị na ndị karịrị kenyere onunu ogwu nke ọgwụ ma ọ bụ were ya, n'agbanyeghị na ndị na-achị contraindications.

Price na analogues nke ọgwụ

Ego ole ka a ọgwụ ọjọọ, "Indapamide"? The price nke ọgwụ nwere ike ịdị iche (dabere na emeputa na ahịa ọgwụ yinye n'akụkụ peeji). Otú ọ dị, na nkezi ngwá ọrụ a nwere ike zụrụ maka 95-100 Russian rubles (30 mbadamba).

Ma ihe na-eme ma ọ bụrụ na onye ọrịa bụ enweghị ike ịchọpụta a ọgwụ ọjọọ, "Indapamide"? Analogues, ego nke bụ nke na-adịghị elu, na-ere ihe fọrọ nke nta ọ bụla na-ere ọgwụ. Ọgwụ ndị a na-agụnye ndị na-esonụ: "indapamide ghara," "Akripamid", "indapamide-Teva", "CP Indamed", "Akripamid ghara", "Ravel CP", "Akuter-Sanovel", "Retapres", "Arindap "" Lorvas "," Arifon "," Pamid "," Arifon ghara "," Tenzar "," Ipres Long "," Vero indapamide, "" Indipam "," Indap "," Indiur "," indapamide-Verte "" Ionic "," indapamide ghara-Teva "," Indapres "," indapamide Sandoz, "" Ionic ghara "," indapamide-OBL "," indapamide Stada "na na.

Were ego na ya ezi uche na-eji dochie ha ọgwụ "Indapamide" na-nditịm ajuru aju. Ha ga inye naanị a dọkịta, nanị mgbe a ọgwụ nnyocha. Ọzọkwa, tupu ewere ndị ọgwụ kwesịrị maara na mmasị ntuziaka.

Nchekwa ọnọdụ nke nkwadebe na ngafe ụbọchị

Drug ụlọ ahịa dị na a akọrọ na ebe gbara ọchịchịrị, nke bụ keerughi obere ụmụaka. nkwadebe nchekwa okpomọkụ ekwesịghị gafere 25 degrees. Adị ndụ nke 3 afọ. Mgbe oge a, na-agwọ ọrịa bụ nditịm machibidoro iwu.