Levonorgestrel: ihe bụ nke a hormone, na n'ihi na nke ọ bụ ya kpatara ke idem?

Ọtụtụ ndị na-eche, sị: levonorgestrel - ihe bụ nke a hormone? Nke a bụ a sịntetik progestagen na-atọghata endometrium ebenata ovulation inhibiting njikọta oocyte kwadebere. Ọzọkwa, ọ nwere ike mucosal anabata ebelata uche na-enwetara. N'isiokwu a, anyị ga-ele anya na nkwadebe nwere a hormone akpọ.

pharmacology

Ọgwụ "Levonorgestrel" - bụ estrogen, nke na-egbochi ndị ebighị nke spam ruru ntọt imi viscosity Njirimara. The ọgwụ na-eme na mpaghara n'ime akpanwa na fallopian tube, na endometrium, na-anọgidesi nke imi, n'ihi follicle-akpali akpali hormone ebelata ya ọrụ.

Ingestion akpọ ọgwụ ifịk ifịk etinye obi gị dum na eriri afọ tract, Bioindication ruo 100%. Na ọbara, ya mmiri na-lekwasị na kacha n'ikuku razovo 75 ml mgbe 60 - 130 nkeji. E lee ya anya hormone interacts na plasma na globulin nkịtị bụ mkpokọta 50%.

Metabolism na-elekwasị anya na-imeju, na n'ezinụlọ ụdị pharmacologically metaboliks. Isi isoenzyme nke a hormone bụ CYP3A4. The ọkara ndụ oge nwere ike ịdịru ruo 30 awa.

Njirimara

Ná nzaghachi nke ajụjụ bụ "Levonorgestrel - ihe bụ nke a hormone?" ga-eduzi ndị na-ntụziaka nke otu aha ọgwụ na-atụ aro nke ịga dọkịta. Indicators n'ozuzu iche uru nke iji nke 1.0 ml / min. / Kg (na plasma). The hormone na-tutu amama tumadi site ureter, a obere akụkụ a na-ewepụ si stool.

Na ọgwụgwọ nke systemic ọdịdị na-ada na-agba na-egosi na akpanwa bụghị ihe karịrị 20 mg kwa ụbọchị, na mgbe afọ ise ada 11. The nkezi mmepụta ọnụego nke hormone dịgasị gburugburu 14 ug / 24 Ọrụ Nchịkwa. N'ime 50-60 ọnwa.

Intrauterine ọgwụ ekwe n'ihi na ndị inyom na a nnọchi hormone ọgwụgwọ na njikọ na estrogen, progestin na-adịghị gụnyere mejupụtara. Levonorgestrel - a hormone implants na plasma 60 nkeji mgbe ochichi. Oke ịta nime ya ka e dekọrọ mgbe 14 ụbọchị nke ngwa.

na-agba akaebe

The ojiji nke a ọgwụ bụ omume na intrauterine ọgwụ, nakwa dị ka ndị na-esonụ mgbe:

• Mgbawa menorrhagia nghazi.
• Ogologo oge ogwu nchebe.
• Mgbochi maka nnọchi Mbelata na estrogen.
• Emergency mberede igbochi afọ.

The hormone levonorgestrel, mmetụta nke nke nwere n'uju akporo, ndị na-esonụ ga-eme nanị mgbe nkwanye nke a dọkịta.

Iji na onunu ogwu

Weere a ọgwụ ọrụ site intrauterine injection - agbara ndi mmadu n'ime eriri akpa nwa oghere. Eji maka 4 ụbọchị mgbe mmekọahụ na ego nke 0,75 1.5 mg. Emergency igbochi afọ ọkachamara ike gwara ọ bụghị na-eme ihe karịrị otu ugboro ọ bụla ọnwa isii.

Iwepụ ịhụ nsọ okirikiri, ọ dị mkpa iji rube isi na-atụ aro usoro onunu ogwu enweghị re-eji. Unu na-eji na-akọ ọgwụ ọnụ dị ka usoro nke na-adịgide adịgide igbochi afọ, dị ka a na-akpalite anya nke mmetụta na-ebelata ịdị irè nke ọgwụ. N'ihe banyere eriri akpa nwa ọbara guzobere mgbe mberede igbochi afọ ukwuu tụrụ aro usoro maka nnyocha site a ọkachamara n'ọrịa ụmụ nwanyị, na mebiri nke menopause ihe karịrị otu izu dị mkpa ka oge na tụụrụ ime ya.

Naanị mgbe oge na asian mkpebi ọkachamara n'ọrịa ụmụ nwanyị na nkịtị ikpe, ọ na-enye ohere maka ndisịn idem nke ọgwụ maka igbochi afọ na umuaka n'oge mberede.

Mee hormone levonorgestrel?

Olee otú ahụ na-eji mmiri ọgwụ ahụ kọwara, na ihe na-eme iji zere mmetụta? Ya mere ajụjụ na-akpọlite ọtụtụ ndị. Ịgbasochi ka ọkachamara ndụmọdụ, na-akwanyere onunu ogwu ma soro ntuziaka - ya emesi mma ojiji nke ọgwụ.

Tupu were, ị ga-agabiga nnyocha nke Navy ọkachamara n'ọrịa ụmụ nwanyị, gụnyere ego mammary glands, pelvic akụkụ, na-eme cervical iteto.

Re-nnyocha a rụrụ mgbe 30-40 ụbọchị mgbe echichi nke a gburugburu, mgbe ahụ, kwa afọ, na mgbe ọ bụla e nwere ihe presuppositions - ọtụtụ mgbe. Nke a intrauterine ọgwụ bụ irè n'ihi 4 5 afọ. Ya echichi ga-emeso nanị na dọkịta ọkachamara a na ubi ma ọ bụ nwere ahụmahụ na-ewere ụdị ọgwụ.

ize ndụ

Women na-ewere ọgwụ ọjọọ na progestogen, ọ bụ omume na-abawanye nke na venous thrombosis na a dị oké egwu oge. Mgbe ndị dị otú ahụ ihe mgbaàmà bụ mkpa buru ngwa ngwa jikoro maka nchoputa na ọgwụgwọ.

Mgbe na ndọrọ ego nke Navy nke Ịmụ nwa resuscitated mgbe ọnwa isii na ọkara nke ndị inyom na-etinyere mgbe 12 ọnwa - karịrị 96 percent. Ogwu nghazi bụ obere irè n'ihi na ọrịa na ibu oké ibu.

contraindications

Eche "Levonorgestrel - ihe bụ nke a hormone?" kwesịrị ịtụle niile contraindications. N'etiti ha:

• Beyond (hyper) uche, tromboflebitnye guzobere.
• Thromboembolism, mgbanwe akwara.
• Cerebrovascular ọrịa nghazi, ime.
• Banyere ingestion: jaundice (gụnyere akụkọ ihe mere eme), enweghị nchịkwa nsogbu bile mmepụta ma ọ bụ imeju, lactation.
• Mmekọahụ ntozu okè.
• Ọzọkwa, maka IUD - ọnụ urogenital ọrịa ugboro ma ọ bụ ike mbufụt na pelvis, ịṅụ oké ọbara endometritis, nnukwu ọrịa imeju.
• Septic abortifacient aka ke akpatre trimester, dysplastic mgbanwe eriri akpa nwa cervix daa ọrịa na a yiri ọbara ọgbụgba nke na-amaghị si malite, malignancies.
• Bịa ma ọ bụ congenital anomalies ezighị fibroids.
• Progestagenoz (akpụ, gụnyere a kansa ara ọnya).

mgbochi

The na ịmachi na-akpata bụ mgbe mkpa maka ọgwụgwọ aka n'ime akpanwa, ebe na-ọ bụrụ na ị nwere ndị na-esonụ mgbaàmà ma ọ bụ ala ala ọrịa:

• inwe isi ọwụwa, a nkịtị na obodo migraine na bịara ikiri ọhụụ, mgbaàmà ndị ọzọ, lekwasịrị anya ekwe omume nke akwara akwara ọrịa;
• doro anya ọbara mgbali elu direction, jaundice, mgbagwoju ebibi Filiks ke ọbara usoro, gụnyere obi ọgụ ụtarị na;
• -arịa ọrịa shuga mellitus.

Ị ga-ozugbo ịkpọ na Mkpochapu nke Navy n'oge guzobere ma ọ bụ ọnụnọ nke ọ bụla n'ime ndị a na-ekwu.

Pregnancy na lactation oge

N'agbanyeghị eziokwu na levonorgestrel - a nwaanyị hormone, ya na ojiji bụ adịghị anakwere n'oge ime. Ọ bụrụ na ọ bịara, ọ na-atụ aro mkpochapu nke usoro n'ihi na eziokwu na nke ọ bụla intrauterine igbochi afọ enwekwu ihe ize ndụ nke na akaghi aka ịmụ nwa na miscarriages. Iduziri nne N'ịchọpụta usoro ma ọ bụ kpochapụ mgbe ụfọdụ iweta ime ọpụpụ na-ewere ọnọdụ na-enweghị usoro. Ọ na-achọ ọkachamara ndụmọdụ na feasibility nke wuru nchupu nke afọ ime na ikpe nke na-apụghị ime nke ziri ezi ogwu mmịpụta.

Mgbe ọ gaghị ekwe omume iji wepụ intrauterine usoro na ihe ngwa ngwa ọchịchọ ịzọpụta ime onye ọrịa kwesịrị maara nke na o kwere omume nsogbu na ihe ize ndụ nwa ruru ka akaghi aka nwa. N'ọnọdụ dị otú ahụ, ị ga-ijide n'aka anya nyochaa ime. Tupu onye ọrịa ga-eweta ozi na ọ ga-ozugbo-agwa banyere niile ihe mgbaàmà, nke ga-enyere na-atụ aro usoro sikwuoro.

lactation

Mgbe ara na-eji "Levonorgestrel" banyere otu ụzọ n'ụzọ iri nke a ọgwụ abatakwa ahụ nwa ọhụrụ. Ara n'ime n'ihi na mberede igbochi afọ ga-kwụsịrị na 1.5 ụbọchị.

na-atụ aro usoro onunu ogwu maka ọgwụgwọ usoro arụnyere na utero, ka ọ bụla progestogen-na-ogwu usoro, ọ bụ ihe e ji mara na ihe a ọkara ọnwa mgbe amuchara nwa nwere dịghị oghom mmetụta na na mmepe nke nwa ya, ọgwụ yighị ka inwe ihe ize ndụ nke nwa ebu n'afọ .

oghom mgbaàmà

Na-alọta nke ajụjụ bụ "Levonorgestrel" - ihe ọ bụ, "ka anya na o kwere omume mmetụta na contraindications nke ọgwụ Ha nwere ike ime na dị iche iche na usoro nke ahụ ahụ na ndị na-esonụ mgbaàmà :.

1. Site ụjọ usoro: ike ọgwụgwụ, ịda mbà n'obi, isi ọwụwa, na ọnọdụ swings.
2. GIT. Vomiting, afọ mgbu, cramps, bloating.
3. Genito-urinary akụkụ. Agba ọbara, nkewa, ihe mgbu, candidiasis, ihe gbasara nke puru nke guzobere nke ịza na benign etuto ahụ.
4. Skin rashes, ngosipụta nke eczema, itching, ọkụ ọkụ, otutu.
5. Ndị ọzọ: ọzịza, nkwonkwo mgbu, mgbali surges, sepsis.

Na obere okwu ọdịdọ nke Akwụkwụ na-adọ, cramps na-ada mbà.

Nchikota na ndị ọzọ ọgwụ ọjọọ eme ihe

Amụ "Levonorgestrel" (ihe ụdị hormone), ọ dị mkpa banyere ekwe omume nke Nchikota na ndị ọzọ ọgwụ ọjọọ na organic ọgwụ ọjọọ. N'ihe banyere nke umi na ajụjụ na inducers nke cytochrome P450 isoenzymes nwere ike ibelata arụmọrụ n'ihi na nke na-abawanye na ya metabolic n'ibu.

Ndị na-esonụ ọgwụ ọjọọ nwere ike belata mmetụta nke "Levonorgestrel":

• Group barbiturates, "Tretinoin", "carbamazepine" ikwọ nwere St. Jọn wort na ya komponatsiyu.
• Ebelata ịdị irè nke anticoagulants, hypoglycemic, anticonvulsant ọgwụ ọjọọ.
• "Levonorgestrel" enwekwu ike nke glucocorticoids na ọbara, na nwekwara ike akpaghasị metabolism.
• N'ihi suppression mmekọahụ Steroid recirculation, n'ihi na reorganization nke nsia na osisi, mụbara ịhụ nsọ ọbara ọgbụgba nwere ike ime mgbe mgbagwoju ngwa nke ọgwụ ụfọdụ.

Otu onye nwere ike ma tinye, na-ekwu banyere otú e si eme "Levonorgestrel" na nke a usọbọ na-akpata na-abawanye na n'akụkụ mmetụta nke ọgwụ ndị ọzọ, ihe ngwọta na ọ bụghị. Bụrụ na nke ovadozu achọ symptomatic ọgwụgwọ.