Sinaflana ude - Ngwa aro

Ude sinaflana bụ otu nke Nde corticosteroids. Isi nọ n'ọrụ mgwa na Nwa bụ fluocinolone acetonide. Nke a ihe onwunwe na-akwadebe synthetically, o nwere pharmacological ọrụ, bụ nke yiri glucocorticosteroids. Ude sinaflana, kpọmkwem onye ọ bụla nke ya molekul agụnye ọzọ nwere ihe abụọ fluorine atọm, ekele a gụnyere ya ná obodo absorption na enwekwukwa ya mgbochi mkpali mmetụta. Isi nọ n'ọrụ mgwa nke ọgwụ nwere nnukwu glucocorticoid ọrụ na fọrọ nke nta ka ọ dịghị mineralocorticoid edinam. Na Nde ngwa nke manu-otite sinaflana nwere antiallergic, antiinflammatory na antipruritic mmetụta, ke adianade do, ọgwụ activates obodo vasodilation.

The ọrụ nke agwọ ọrịa bụ usoro maka inhibiting phospholipase A2. Ọ na-adị mgbochi ọrụ nke a nyere enzyme, ma si otú na-egbochi na ntughari nke arachidonic acid n'ime a pharmacologically ifịk ụdị. N'ihi kwuru mmetụta, mbelata ego nke leukotrienes na prostaglandins, nke bụ isi ndị ogbugbo nke mbufụt.

N'ihi na eziokwu na histamine ntọhapụ na-ebelata, sinaflana ude akpata mgbochi nke hypersensitivity Jeremaya mere. Mgbe n'itinye sinaflana budata mbelata ihe ize ndụ nke mmepe nke exudative Jeremaya mere na n'ihi na a na ibelata nke vaskụla lumen. Ọzọkwa, a ọgwụ na-ebelata protein njikọ na collagen deposition.

Ude na-etinyere topically, ọ penetrates ọma site stratum corneum nke epidermis na-agbakọ dermis. Sị na nkwadebe bụ bụghị biotransformed na akpụkpọ. Ọ ga-kwuru na systemic absorption na-eto eto na ụmụ dị nnọọ elu karịa ndị okenye.

Sinaflana ude - ntuziaka maka ojiji

Jiri nke nkwadebe na-atụ aro dị iche iche akpụkpọ ọrịa ebe ọ dị mkpa na-eduzi ọgwụ eji glucocorticoids. Ndị a bụ ọrịa:

• discoid lupus erythematosus, lichen planus;
• psoriasis na seborrhea nke anụ;
• ọnụnọ nke mgbanwe degrees nke eczematous ọnya;
• atopic dermatitis na anabata akpụkpọ Jeremaya mere, nakwa dị ka pruritus;
• omume nke mbụ ogo Burns, gụnyere ntachu;
• ata aru nke dị iche iche ụmụ ahụhụ.

Ude sinaflana (ntuziaka maka ojiji nke kwuru Nwa kama mfe) na-etinyere na otụk ebe ugboro atọ n'ụbọchị. Buru n'uche na na etinye ude ọ ga-ubé ụlọ akwụkwọ ji agwụ n'ime otụk ebe. Ọgwụgwọ na a ọgwụ na-ẹkenịmde maka 5-10 ụbọchị, ma ọ bụrụ na ọ dị mkpa na ọ ga-aka iso ruo ụbọchị 25. Ngwa nke manu-otite na-mwute na nnukwu ebe nke anụ adịghị atụ aro.

Ekwe Omume mmetụta

Ọ bụrụ na mmanụ otite na-eji maka a ogologo oge, onye ọrịa nwere ike atrophy nke anụ, na ọbụna ịzụlite necrosis. Ọ bụrụ na ị na-etinye ya ibu ma ọ bụ mwute ebe nke anụ ahụ, ọ nwere ike na-emere hypoadrenalism.

Protivopokazaniyak ojiji nke ọgwụ:

• ọnụnọ ke a ndidi nke onye hypersensitivity na mmiri nke ọgwụ;
• na-efe efe ọrịa akpụkpọ nke dị iche iche etiology;
• Ọ na-adịghị emetụta ude na akpụkpọ saịtị ebe e nwere ọnyá ọnya, nwekwara ike ide ude na-emeghe ọnyá;
• Ọ machibidoro ojiji nke a gị n'ụlọnga ke ime na ụkwara nta anụ.

Ebe ọ bụ na agwọ ọrịa na-etinyere topically, ọ na-apụghị ovadozu.

Nọgidenụ na-ude sinaflana n'ebe kpọmkwem ìhè anyanwụ na a akọrọ ụlọ na ihere okpomọkụ ekwesịghị gafere 30 degrees.

Cheta na ihe ndị a ọgwụ ọjọọ eme ihe ga-kpọkwasịwo a oge na a dọkịta.